Institution · ActiveSite Pharmaceuticals (United States)

Most cited papers from ActiveSite Pharmaceuticals (United States)

ActiveSite Pharmaceuticals (United States)

What are the most cited papers from ActiveSite Pharmaceuticals (United States)?

The most cited paper from ActiveSite Pharmaceuticals (United States) is "Activation of the β2-Adrenergic Receptor Involves Disruption of an Ionic Lock between the Cytoplasmic Ends of Transmembrane Segments 3 and 6" (Juan Antonio Ballesteros‐Cánovas, Anne Dam Jensen, George Liapakis et al., 2001), with 622 citations. Next come "Structural Mimicry in G Protein-Coupled Receptors: Implications of the High-Resolution Structure of Rhodopsin for Structure-Function Analysis of Rhodopsin-Like Receptors" (440) and "β2 Adrenergic Receptor Activation" (429).

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Showing 27 of 27 papers. Every paper is listed.

Most cited papers, sortable by citations and release date
#	Paper
1	Activation of the β2-Adrenergic Receptor Involves Disruption of an Ionic Lock between the Cytoplasmic Ends of Transmembrane Segments 3 and 6 Juan Antonio Ballesteros‐Cánovas, Anne Dam Jensen, George Liapakis et al. · Journal of Biological Chemistry Open access	Aug 2001	622
2	Structural Mimicry in G Protein-Coupled Receptors: Implications of the High-Resolution Structure of Rhodopsin for Structure-Function Analysis of Rhodopsin-Like Receptors Juan Antonio Ballesteros‐Cánovas, Lei Shi, Jonathan A. Javitch · Molecular Pharmacology	Jul 2001	440
3	β2 Adrenergic Receptor Activation Lei Shi, George Liapakis, Rui Xu et al. · Journal of Biological Chemistry Open access	Oct 2002	429
4	Regulation of vertebrate eye development by Rx genes Travis J. Bailey, Heithem M. El‐Hodiri, Li Zhang et al. · The International Journal of Developmental Biology Open access	2004	177
5	Agonist-induced Conformational Changes at the Cytoplasmic Side of Transmembrane Segment 6 in the β2 Adrenergic Receptor Mapped by Site-selective Fluorescent Labeling Anne Dam Jensen, Frank Guarnieri, Søren G. F. Rasmussen et al. · Journal of Biological Chemistry Open access	Mar 2001	144
6	Hyperglycemia-induced cerebral hematoma expansion is mediated by plasma kallikrein Jia Liu, Benbo Gao, Allen C. Clermont et al. · Nature Medicine Open access	23 Jan 2011	142
7	G protein-coupled receptor drug discovery: implications from the crystal structure of rhodopsin. J. Ballesteros, Krzysztof Palczewski · PubMed Open access	Sep 2001	122
8	Simultaneous Measurements of Mitochondrial NADH and Ca2+ during Increased Work in Intact Rat Heart Trabeculae Ralf Peter Brandes, Donald M. Bers · Biophysical Journal Open access	Aug 2002	114
9	BACE1 gene deletion: Impact on behavioral function in a model of Alzheimer's disease Dione T. Kobayashi, Michelle Zeller, Tracy A. Cole et al. · Neurobiology of Aging	Mar 2007	111
10	Characterization of retinal guanylate cyclase‐activating protein 3 (GCAP3) from zebrafish to man Yoshikazu Imanishi, Ning Li, Izabela Sokal et al. · European Journal of Neuroscience Open access	2002	98
11	Plasma Kallikrein Mediates Retinal Vascular Dysfunction and Induces Retinal Thickening in Diabetic Rats Allen C. Clermont, Tamie J. Chilcote, Takeshi Kita et al. · Diabetes Open access	28 Mar 2011	96
12	Ser and Thr Residues Modulate the Conformation of Pro-Kinked Transmembrane α-Helices Xavier Deupí, Mireia Olivella, Cédric Govaerts et al. · Biophysical Journal Open access	2004	93
13	Linking agonist binding to histamine H1 receptor activation Aldo Jongejan, Martijn W.P. Bruysters, Juan Antonio Ballesteros‐Cánovas et al. · Nature Chemical Biology Open access	19 Jun 2005	93
14	The First Transmembrane Segment of the Dopamine D2 Receptor: Accessibility in the Binding-Site Crevice and Position in the Transmembrane Bundle Lei Shi, Merrill M. Simpson, Juan Antonio Ballesteros‐Cánovas et al. · Biochemistry	22 Sep 2001	71
15	Selectin Antagonists Suzanne J. Romano · Treatments in Respiratory Medicine Open access	2005	70
16	Plasma Kallikrein Mediates Angiotensin II Type 1 Receptor–Stimulated Retinal Vascular Permeability Joanna A. Phipps, Allen C. Clermont, Sukanto Sinha et al. · Hypertension Open access	6 Jan 2009	69
17	β‐Amyloid peptide in regulated secretory vesicles of chromaffin cells: evidence for multiple cysteine proteolytic activities in distinct pathways for β‐secretase activity in chromaffin vesicles VIVIAN Y. H. HOOK, Thomas Toneff, Wade H. Aaron et al. · Journal of Neurochemistry	Apr 2002	57
18	Improvements in G protein-coupled receptor purification yield light stable rhodopsin crystals David Salom, Isolde Le Trong, Ehmke Pohl et al. · Journal of Structural Biology	3 Jun 2006	53
19	Structural motifs as functional microdomains in G‐protein‐coupled receptors: Energetic considerations in the mechanism of activation of the serotonin 5‐HT2A receptor by disruption of the ionic lock of the arginine cage* Irache Visiers, Barbara Jones Ebersole, Stella M. Dracheva et al. · International Journal of Quantum Chemistry	2002	49
20	Crystal packing analysis of Rhodopsin crystals David T. Lodowski, David Salom, Isolde Le Trong et al. · Journal of Structural Biology Open access	10 Feb 2007	41
21	Increased Perioperative B-type Natriuretic Peptide Associates with Heart Failure Hospitalization or Heart Failure Death after Coronary Artery Bypass Graft Surgery Amanda A. Fox, Luigino Nascimben, Simon C. Body et al. · Anesthesiology Open access	21 May 2013	37
22	Expression of Functional G Protein-Coupled Receptors in Photoreceptors of TransgenicXenopus laevis Li Zhang, David Salom, Jianhua He et al. · Biochemistry	14 Oct 2005	29
23	Lead optimization and structure-based design of potent and bioavailable deoxycytidine kinase inhibitors Theodore C. Jessop et al. · Bioorganic & Medicinal Chemistry Letters Open access	26 Sep 2009	10
24	Reprint of “Crystal packing analysis of Rhodopsin crystals” [J. Struct. Biol. 158 (2007) 455–462]☆ David T. Lodowski, David Salom, Isolde Le Trong et al. · Journal of Structural Biology	27 Jul 2007	5
25	Product Application Focus: Stable Luciferase Reporter Cell Lines for Signal Transduction Pathway Readout Using GAL4 Fusion Transactivators Lisa E. Hexdall, Chaofeng Zheng · BioTechniques Open access	May 2001	4
26	Conformational Plasticity of GPCR Binding Sites Xavier Deupí, Cédric Govaerts, Lei Shi et al. · Contemporary clinical neuroscience Book chapter	2005	3
27	Effects of Plasma Kallikrein on Retinal Vascular Functions in Diabetes Allen C. Clermont, J. Liu, Paola Riva et al. · Investigative Ophthalmology & Visual Science	17 Apr 2010	0

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.