| 1 |
Orally administered L. lactis secreting an anti-TNF Nanobody demonstrate efficacy in chronic colitis
Klaas Vandenbroucke, Hans de Haard, Els Beirnaert et al. · Mucosal Immunology
Open access |
30 Sep 2009 |
291 |
| 2 |
Lactocepin Secreted By Lactobacillus Exerts Anti-Inflammatory Effects By Selectively Degrading Proinflammatory Chemokines
Marie‐Anne von Schillde, Gabriele Hörmannsperger, Monika Weiher et al. · Cell Host & Microbe
Open access |
Apr 2012 |
240 |
| 3 |
Reversal of autoimmune diabetes by restoration of antigen-specific tolerance using genetically modified Lactococcus lactis in mice
Tatiana Takiishi, Hannelie Korf, Tom L. Van Belle et al. · Journal of Clinical Investigation
Open access |
9 Apr 2012 |
201 |
| 4 |
Engineering lactococci and lactobacilli for human health
Luis G. Bermúdez‐Humarán, Camille Aubry, Jean‐Paul Motta et al. · Current Opinion in Microbiology
Review |
Jun 2013 |
166 |
| 5 |
Role of the 5-HT7 Receptor in the Central Nervous System: from Current Status to Future Perspectives
Anne Matthys, Guy Haegeman, Kathleen Van Craenenbroeck et al. · Molecular Neurobiology
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21 Mar 2011 |
160 |
| 6 |
Oral Delivery of Glutamic Acid Decarboxylase (GAD)-65 and IL10 byLactococcus lactisReverses Diabetes in Recent-Onset NOD Mice
Sofie Robert, Conny A. Gysemans, Tatiana Takiishi et al. · Diabetes
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28 Mar 2014 |
159 |
| 7 |
Surface area assessment of the murine intestinal tract as a prerequisite for oral dose translation from mouse to man
Christophe R. Casteleyn, Anamaria Rekecki, A Van Der Aa et al. · Laboratory Animals
Open access |
10 Dec 2009 |
149 |
| 8 |
Phase 1b, multicenter, single blinded, placebo‐controlled, sequential dose escalation study to assess the safety and tolerability of topically applied AG013 in subjects with locally advanced head and neck cancer receiving induction chemotherapy
Sewanti Atul Limaye, Robert I. Haddad, Fiona Cilli et al. · Cancer
Open access |
24 Sep 2013 |
131 |
| 9 |
AG013, a mouth rinse formulation of Lactococcus lactis secreting human Trefoil Factor 1, provides a safe and efficacious therapeutic tool for treating oral mucositis
Silvia Caluwaerts, Klaas Vandenbroucke, Lothar Steidler et al. · Oral Oncology
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10 Jun 2010 |
129 |
| 10 |
Induction of Antigen-Specific Tolerance by Oral Administration of Lactococcus lactis Delivered Immunodominant DQ8-Restricted Gliadin Peptide in Sensitized Nonobese Diabetic Ab° Dq8 Transgenic Mice
Inge L. Huibregtse, Eric Vincent Marietta, Shadi Rashtak et al. · The Journal of Immunology
Open access |
28 Jul 2009 |
87 |
| 11 |
Reversible changes in serum immunoglobulin galactosylation during the immune response and treatment of inflammatory autoimmune arthritis
Katrien Van Beneden, Ken T. Coppieters, Wouter Laroy et al. · Annals of the Rheumatic Diseases
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4 Sep 2008 |
51 |
| 12 |
Actobiotics™ as a Novel Method for Cytokine Delivery
Lothar Steidler, Pieter Rottiers, Bernard J. Coulie · Annals of the New York Academy of Sciences
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Dec 2009 |
39 |
| 13 |
Modulation of Gut-Associated Lymphoid Tissue Functions with Genetically ModifiedLactococcus lactis
Pieter Rottiers, Tim De Smedt, Lothar Steidler · International Reviews of Immunology
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10 Nov 2009 |
28 |
| 14 |
Immunomodulation by genetically engineered lactic acid bacteria
Karolien Van Huynegem · Frontiers in bioscience
Open access |
2009 |
27 |
| 15 |
Genetically Engineered Lactococcus lactis Secreting Murine IL‐10 Modulates the Functions of Bone Marrow‐Derived Dendritic Cells in the Presence of LPS
Michael Loos, E. Remaut, Pieter Rottiers et al. · Scandinavian Journal of Immunology
Open access |
31 Dec 2008 |
12 |
| 16 |
Expression of galectins‐1, ‐3 and ‐4 varies with strain and type of experimental colitis in mice
Anne Mathieu, Nathalie Nagy, Christine Decaestecker et al. · International Journal of Experimental Pathology
Open access |
5 Nov 2008 |
12 |
| 17 |
Trimming of two major type 1 diabetes driving antigens, GAD65 and IA-2, allows for successful expression in Lactococcus lactis
Samuel Robert, Karolien Van Huynegem, Conny A. Gysemans et al. · Beneficial Microbes
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10 Jan 2015 |
11 |
| 18 |
Biochemical and pharmacological study of N‐linked glycosylation of the human serotonin 5‐HT7(a) receptor
Evelien Gellynck, Kjetil Wessel Andressen, Béatrice Lintermans et al. · FEBS Journal
Open access |
27 Mar 2012 |
9 |
| 19 |
PTU-103 Intra-luminal Interleukin (il)-27 Is A Potential Future Therapeutic For Inflammatory Bowel Disease
MH McLean, ML Hanson, Bert Gold et al. · Gut
Open access |
Jun 2014 |
2 |
| 20 |
112
Miranda L. Hanson, Julie A. Hixon, Wenqing Li et al. · Cytokine
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14 Aug 2013 |
1 |
| 21 |
Clinical development of lactocepin: a novel bacterial biologic?
Karolien Van Huynegem, Lothar Steidler · Expert Review of Clinical Immunology
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Sep 2012 |
1 |
| 22 |
Antigen-Specific Therapy With Human Proinsulin and IL10 in Combination With Short-Course Monoclonal CD3 Antibody in Preclinical Models of Islet Transplant.
Monteiro J. Carvalho Mori da, Tatiana Takiishi, Tom Van Belle et al. · Transplantation
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Jul 2014 |
0 |
| 23 |
Mucosal Delivery of IL-27 Attenuates Murine Enterocolitis via T Cell-Derived IL-10
Scott Kenneth Durum, Julie A. Hixon, Wenqing Li et al. · Inflammatory Bowel Diseases
Open access |
Dec 2012 |
0 |
| 24 |
OR.71. Combination Therapy of Short-term Low-dose Anti-CD3 and Oral Administration of Genetically-modified Lactococcus Lactis Secreting Insulin and IL-10 Enhances Remission in New-onset Diabetic NOD Mice
Tatiana Takiishi, Conny A. Gysemans, Veerle Snoeck et al. · Clinical Immunology
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2009 |
0 |
| 25 |
SS1-1 Lactococcus lactis expressing IL-27: Therapeutic promise in inflammatory bowel disease
Scott Kenneth Durum, Wenqing Li, Julie A. Hixon et al. · Cytokine
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6 Sep 2010 |
0 |
| 26 |
PS1-27 Lactococcus lactis expressing IL-27: A potential therapeutic for inflammatory bowel disease
Miranda L. Hanson, Julie A. Hixon, Wenqing Li et al. · Cytokine
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6 Sep 2010 |
0 |