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Most cited papers from ActoGeniX (Belgium)

What are the most cited papers from ActoGeniX (Belgium)?

The most cited paper from ActoGeniX (Belgium) is "Orally administered L. lactis secreting an anti-TNF Nanobody demonstrate efficacy in chronic colitis" (Klaas Vandenbroucke, Hans de Haard, Els Beirnaert et al., 2009), with 291 citations. Next come "Lactocepin Secreted By Lactobacillus Exerts Anti-Inflammatory Effects By Selectively Degrading Proinflammatory Chemokines" (240) and "Reversal of autoimmune diabetes by restoration of antigen-specific tolerance using genetically modified Lactococcus lactis in mice" (201).

Showing 26 of 26 papers. Every paper is listed.

Most cited papers, sortable by citations and release date
#Paper
1 Orally administered L. lactis secreting an anti-TNF Nanobody demonstrate efficacy in chronic colitis Klaas Vandenbroucke, Hans de Haard, Els Beirnaert et al. · Mucosal Immunology Open access 30 Sep 2009 291
2 Lactocepin Secreted By Lactobacillus Exerts Anti-Inflammatory Effects By Selectively Degrading Proinflammatory Chemokines Marie‐Anne von Schillde, Gabriele Hörmannsperger, Monika Weiher et al. · Cell Host & Microbe Open access Apr 2012 240
3 Reversal of autoimmune diabetes by restoration of antigen-specific tolerance using genetically modified Lactococcus lactis in mice Tatiana Takiishi, Hannelie Korf, Tom L. Van Belle et al. · Journal of Clinical Investigation Open access 9 Apr 2012 201
4 Engineering lactococci and lactobacilli for human health Luis G. Bermúdez‐Humarán, Camille Aubry, Jean‐Paul Motta et al. · Current Opinion in Microbiology Review Jun 2013 166
5 Role of the 5-HT7 Receptor in the Central Nervous System: from Current Status to Future Perspectives Anne Matthys, Guy Haegeman, Kathleen Van Craenenbroeck et al. · Molecular Neurobiology 21 Mar 2011 160
6 Oral Delivery of Glutamic Acid Decarboxylase (GAD)-65 and IL10 byLactococcus lactisReverses Diabetes in Recent-Onset NOD Mice Sofie Robert, Conny A. Gysemans, Tatiana Takiishi et al. · Diabetes 28 Mar 2014 159
7 Surface area assessment of the murine intestinal tract as a prerequisite for oral dose translation from mouse to man Christophe R. Casteleyn, Anamaria Rekecki, A Van Der Aa et al. · Laboratory Animals Open access 10 Dec 2009 149
8 Phase 1b, multicenter, single blinded, placebo‐controlled, sequential dose escalation study to assess the safety and tolerability of topically applied AG013 in subjects with locally advanced head and neck cancer receiving induction chemotherapy Sewanti Atul Limaye, Robert I. Haddad, Fiona Cilli et al. · Cancer Open access 24 Sep 2013 131
9 AG013, a mouth rinse formulation of Lactococcus lactis secreting human Trefoil Factor 1, provides a safe and efficacious therapeutic tool for treating oral mucositis Silvia Caluwaerts, Klaas Vandenbroucke, Lothar Steidler et al. · Oral Oncology 10 Jun 2010 129
10 Induction of Antigen-Specific Tolerance by Oral Administration of Lactococcus lactis Delivered Immunodominant DQ8-Restricted Gliadin Peptide in Sensitized Nonobese Diabetic Ab° Dq8 Transgenic Mice Inge L. Huibregtse, Eric Vincent Marietta, Shadi Rashtak et al. · The Journal of Immunology Open access 28 Jul 2009 87
11 Reversible changes in serum immunoglobulin galactosylation during the immune response and treatment of inflammatory autoimmune arthritis Katrien Van Beneden, Ken T. Coppieters, Wouter Laroy et al. · Annals of the Rheumatic Diseases 4 Sep 2008 51
12 Actobiotics™ as a Novel Method for Cytokine Delivery Lothar Steidler, Pieter Rottiers, Bernard J. Coulie · Annals of the New York Academy of Sciences Dec 2009 39
13 Modulation of Gut-Associated Lymphoid Tissue Functions with Genetically ModifiedLactococcus lactis Pieter Rottiers, Tim De Smedt, Lothar Steidler · International Reviews of Immunology 10 Nov 2009 28
14 Immunomodulation by genetically engineered lactic acid bacteria Karolien Van Huynegem · Frontiers in bioscience Open access 2009 27
15 Genetically Engineered Lactococcus lactis Secreting Murine IL‐10 Modulates the Functions of Bone Marrow‐Derived Dendritic Cells in the Presence of LPS Michael Loos, E. Remaut, Pieter Rottiers et al. · Scandinavian Journal of Immunology Open access 31 Dec 2008 12
16 Expression of galectins‐1, ‐3 and ‐4 varies with strain and type of experimental colitis in mice Anne Mathieu, Nathalie Nagy, Christine Decaestecker et al. · International Journal of Experimental Pathology Open access 5 Nov 2008 12
17 Trimming of two major type 1 diabetes driving antigens, GAD65 and IA-2, allows for successful expression in Lactococcus lactis Samuel Robert, Karolien Van Huynegem, Conny A. Gysemans et al. · Beneficial Microbes 10 Jan 2015 11
18 Biochemical and pharmacological study of N‐linked glycosylation of the human serotonin 5‐HT7(a) receptor Evelien Gellynck, Kjetil Wessel Andressen, Béatrice Lintermans et al. · FEBS Journal Open access 27 Mar 2012 9
19 PTU-103 Intra-luminal Interleukin (il)-27 Is A Potential Future Therapeutic For Inflammatory Bowel Disease MH McLean, ML Hanson, Bert Gold et al. · Gut Open access Jun 2014 2
20 112 Miranda L. Hanson, Julie A. Hixon, Wenqing Li et al. · Cytokine 14 Aug 2013 1
21 Clinical development of lactocepin: a novel bacterial biologic? Karolien Van Huynegem, Lothar Steidler · Expert Review of Clinical Immunology Sep 2012 1
22 Antigen-Specific Therapy With Human Proinsulin and IL10 in Combination With Short-Course Monoclonal CD3 Antibody in Preclinical Models of Islet Transplant. Monteiro J. Carvalho Mori da, Tatiana Takiishi, Tom Van Belle et al. · Transplantation Jul 2014 0
23 Mucosal Delivery of IL-27 Attenuates Murine Enterocolitis via T Cell-Derived IL-10 Scott Kenneth Durum, Julie A. Hixon, Wenqing Li et al. · Inflammatory Bowel Diseases Open access Dec 2012 0
24 OR.71. Combination Therapy of Short-term Low-dose Anti-CD3 and Oral Administration of Genetically-modified Lactococcus Lactis Secreting Insulin and IL-10 Enhances Remission in New-onset Diabetic NOD Mice Tatiana Takiishi, Conny A. Gysemans, Veerle Snoeck et al. · Clinical Immunology 2009 0
25 SS1-1 Lactococcus lactis expressing IL-27: Therapeutic promise in inflammatory bowel disease Scott Kenneth Durum, Wenqing Li, Julie A. Hixon et al. · Cytokine 6 Sep 2010 0
26 PS1-27 Lactococcus lactis expressing IL-27: A potential therapeutic for inflammatory bowel disease Miranda L. Hanson, Julie A. Hixon, Wenqing Li et al. · Cytokine 6 Sep 2010 0

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.