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Most cited papers from Acumen Pharmaceuticals (United States)

What are the most cited papers from Acumen Pharmaceuticals (United States)?

The most cited paper from Acumen Pharmaceuticals (United States) is "Revised criteria for diagnosis and staging of Alzheimer's disease: Alzheimer's Association Workgroup" (Clifford R. Jack, Jeffrey Scott Andrews, Thomas G. Beach et al., 2024), with 2,670 citations. Next come "Early role of vascular dysregulation on late-onset Alzheimer’s disease based on multifactorial data-driven analysis" (1,244) and "Alzheimer's disease-affected brain: Presence of oligomeric Aβ ligands (ADDLs) suggests a molecular basis for reversible memory loss" (1,069).

Showing 50 of 89 papers. Every paper is listed.

Most cited papers, sortable by citations and release date
#Paper
1 Revised criteria for diagnosis and staging of Alzheimer's disease: Alzheimer's Association Workgroup Clifford R. Jack, Jeffrey Scott Andrews, Thomas G. Beach et al. · Alzheimer s & Dementia Open access 27 Jun 2024 2,670
2 Early role of vascular dysregulation on late-onset Alzheimer’s disease based on multifactorial data-driven analysis Yasser Iturria‐Medina et al. · Nature Communications Open access316 authors 21 Jun 2016 1,244
3 Alzheimer's disease-affected brain: Presence of oligomeric Aβ ligands (ADDLs) suggests a molecular basis for reversible memory loss Yuesong Gong, Lei Chang, Kirsten L. Viola et al. · Proceedings of the National Academy of Sciences Open access 18 Aug 2003 1,069
4 Synaptic Targeting by Alzheimer's-Related Amyloid β Oligomers Pascale N. Lacor, Maria C. F. Buniel, Lei Chang et al. · Journal of Neuroscience Open access 10 Nov 2004 964
5 Uncovering the heterogeneity and temporal complexity of neurodegenerative diseases with Subtype and Stage Inference Alexandra L. Young et al. · Nature Communications Open access380 authors 9 Oct 2018 613
6 Amyloid beta oligomers induce impairment of neuronal insulin receptors Weiqin Zhao, Fernanda G. De Felice, Sara J. Fernandez et al. · The FASEB Journal 24 Aug 2007 591
7 Self-Assembly of Aβ 1 - 42 into Globular Neurotoxins Brett A. Chromy, Richard J. Nowak, Mary P. Lambert et al. · Biochemistry 17 Oct 2003 530
8 Alzheimer's disease-type neuronal tau hyperphosphorylation induced by Aβ oligomers Fernanda G. De Felice, Diana Wu, Mary P. Lambert et al. · Neurobiology of Aging Open access 25 Apr 2007 429
9 Predicting Alzheimer’s disease progression using multi-modal deep learning approach Garam Lee et al. · Scientific Reports Open access315 authors 13 Feb 2019 415
10 Basal forebrain degeneration precedes and predicts the cortical spread of Alzheimer’s pathology Taylor W. Schmitz et al. · Nature Communications Open access313 authors 4 Nov 2016 365
11 Ferritin levels in the cerebrospinal fluid predict Alzheimer’s disease outcomes and are regulated by APOE Scott Ayton et al. · Nature Communications Open access314 authors 19 May 2015 332
12 Monoclonal antibodies that target pathological assemblies of Aβ Mary P. Lambert, Pauline T. Velasco, Lei Chang et al. · Journal of Neurochemistry 21 Aug 2006 316
13 Targeting the proper amyloid-beta neuronal toxins: a path forward for Alzheimer’s disease immunotherapeutics William F. Goure, Grant A. Krafft, Jasna Jerecı̀ć et al. · Alzheimer s Research & Therapy Open access 9 Jul 2014 196
14 Recommendations From the International Consensus Conference on Anemia Management in Surgical Patients (ICCAMS) Aryeh Shander et al. · Annals of Surgery Open access 21 Sep 2022 191
15 Revised criteria for the diagnosis and staging of Alzheimer’s disease Clifford R. Jack, Scott J. Andrews, Thomas G. Beach et al. · Nature Medicine Open access 28 Jun 2024 185
16 Insulin Receptor Dysfunction Impairs Cellular Clearance of Neurotoxic Oligomeric Aβ Wei-Qin Zhao, Pascale N. Lacor, Hui Chen et al. · Journal of Biological Chemistry Open access May 2009 159
17 Days to criterion as an indicator of toxicity associated with human Alzheimer amyloid‐β oligomers Sam Gandy, Adam J. Simon, John Steele et al. · Annals of Neurology Open access 14 Apr 2010 140
18 Challenges and Opportunities with Causal Discovery Algorithms: Application to Alzheimer’s Pathophysiology Xinpeng Shen et al. · Scientific Reports Open access309 authors 19 Feb 2020 137
19 A highly sensitive novel immunoassay specifically detects low levels of soluble Aβ oligomers in human cerebrospinal fluid Ting Yang, Tiernan T. O’Malley, Daniel Kanmert et al. · Alzheimer s Research & Therapy Open access 3 Feb 2015 127
20 Non-coding variability at the APOE locus contributes to the Alzheimer’s risk Xiaopu Zhou et al. · Nature Communications Open access319 authors 25 Jul 2019 125
21 The case for soluble Aβ oligomers as a drug target in Alzheimer's disease Franz F. Hefti, William F. Goure, Jasna Jerecı̀ć et al. · Trends in Pharmacological Sciences Review 10 Apr 2013 120
22 The BIN1 rs744373 SNP is associated with increased tau-PET levels and impaired memory Nicolai Franzmeier et al. · Nature Communications Open access308 authors 16 Apr 2019 118
23 ADDLs and the signaling web that leads to Alzheimer’s disease Grant A. Krafft, William L. Klein · Neuropharmacology 21 Jul 2010 109
24 Predicting Short-term MCI-to-AD Progression Using Imaging, CSF, Genetic Factors, Cognitive Resilience, and Demographics Yogatheesan Varatharajah et al. · Scientific Reports Open access309 authors 19 Feb 2019 104
25 Deep learning-based polygenic risk analysis for Alzheimer’s disease prediction Xiaopu Zhou et al. · Communications Medicine Open access327 authors 6 Apr 2023 72
26 Multiple Sclerosis Performance Test: Technical Development and Usability Jane Rhodes, David Schindler, Stephen M. Rao et al. · Advances in Therapy Open access 3 May 2019 64
27 Advancing Alzheimer's disease diagnosis, treatment, and care: Recommendations from the Ware Invitational Summit Mary Duffin Naylor et al. · Alzheimer s & Dementia Open access Sep 2012 57
28 ACU193: An Immunotherapeutic Poised to Test the Amyloid β Oligomer Hypothesis of Alzheimer’s Disease Grant A. Krafft, Jasna Jerecı̀ć, Eric Siemers et al. · Frontiers in Neuroscience Open access 26 Apr 2022 53
29 An IL1RL1 genetic variant lowers soluble ST2 levels and the risk effects of APOE-ε4 in female patients with Alzheimer’s disease Yuanbing Jiang et al. · Nature Aging Open access333 authors 15 Jul 2022 51
30 Multimodal Hippocampal Subfield Grading For Alzheimer’s Disease Classification Kilian Hett et al. · Scientific Reports Open access317 authors 25 Sep 2019 47
31 The novel α7 nicotinic acetylcholine receptor agonist EVP-6124 enhances dopamine, acetylcholine, and glutamate efflux in rat cortex and nucleus accumbens Mei Huang, Anna R. Felix, Dorothy G. Flood et al. · Psychopharmacology 8 May 2014 47
32 The trend of disruption in the functional brain network topology of Alzheimer’s disease Alireza Fathian et al. · Scientific Reports Open access319 authors 2 Sep 2022 43
33 Multiplexed high content screening assays create a systems cell biology approach to drug discovery D. Lansing Taylor, Kenneth A. Giuliano · Drug Discovery Today Technologies Jun 2005 43
34 A Personal Perspective on High-Content Screening (HCS): From the Beginning D. Lansing Taylor · SLAS DISCOVERY Open access 16 Jul 2010 42
35 Simulating oligomerization at experimental concentrations and long timescales: A Markov state model approach Nicholas W. Kelley, Vaibhav Vishal, Grant A. Krafft et al. · The Journal of Chemical Physics Open access 4 Dec 2008 41
36 Large-scale genomics unveil polygenic architecture of human cortical surface area Chi‐Hua Chen et al. · Nature Communications Open access108 authors 20 Jul 2015 36
37 An acute functional screen identifies an effective antibody targeting amyloid-β oligomers based on calcium imaging Xueying Wang, Ksenia V. Kastanenka, Michal Arbel‐Ornath et al. · Scientific Reports Open access 9 Mar 2018 34
38 FAM222A encodes a protein which accumulates in plaques in Alzheimer’s disease Tingxiang Yan et al. · Nature Communications Open access346 authors 21 Jan 2020 33
39 Characterization of Human Coronary Sinus Valves by Direct Visualization during Biventricular Pacemaker Implantation Daejoon Anh, Christian S. Eversull, Henry A. Chen et al. · Pacing and Clinical Electrophysiology 20 Dec 2007 33
40 Correlation between Alzheimer’s disease and type 2 diabetes using non-negative matrix factorization Yeonwoo Chung et al. · Scientific Reports Open access312 authors 27 Jul 2021 32
41 Genetic studies of plasma analytes identify novel potential biomarkers for several complex traits Yuetiva K. Deming et al. · Scientific Reports Open access351 authors 4 Jan 2016 32
42 A Novel Joint Brain Network Analysis Using Longitudinal Alzheimer’s Disease Data Suprateek Kundu et al. · Scientific Reports Open access320 authors 20 Dec 2019 27
43 ACU193, a Monoclonal Antibody that Selectively Binds Soluble Aβ Oligomers: Development Rationale, Phase 1 Trial Design, and Clinical Development Plan Eric Siemers, J. Hitchcock, Karen L Sundell et al. · The Journal of Prevention of Alzheimer s Disease Open access 19 Oct 2022 26
44 Benefits and risks of FDA‐approved amyloid‐targeting antibodies for treatment of early Alzheimer's disease: Navigating clinician‐patient engagement Dorene M. Rentz, Paul S. S. Aisen, Alireza Atri et al. · Alzheimer s & Dementia Open access 22 Sep 2024 25
45 Discovery of ADDL-Targeting Small Molecule Drugs for Alzheimers Disease Gary C. Look, Jasna Jerecı̀ć, Diana Cherbavaz et al. · Current Alzheimer Research Dec 2007 23
46 Early human experience with use of a deflectable fiberoptic endocardial visualization catheter to facilitate coronary sinus cannulation Daejoon Anh, Henry A. Chen, Christian S. Eversull et al. · Heart Rhythm 6 May 2006 21
47 A telescope GWAS analysis strategy, based on SNPs-genes-pathways ensamble and on multivariate algorithms, to characterize late onset Alzheimer’s disease Margherita Squillario et al. · Scientific Reports Open access316 authors 21 Jul 2020 20
48 Applications of Cellular Systems Biology in Breast Cancer Patient Stratification and Diagnostics Rebecca J. Critchley-Thorne, Steven V. Miller, D. Lansing Taylor et al. · Combinatorial Chemistry & High Throughput Screening 19 Sep 2009 16
49 A semi-mechanism approach based on MRI and proteomics for prediction of conversion from mild cognitive impairment to Alzheimer’s disease Haochen Liu et al. · Scientific Reports Open access316 authors 7 Jun 2016 15
50 Pattern Discovery in Brain Imaging Genetics via SCCA Modeling with a Generic Non-convex Penalty Lei Du et al. · Scientific Reports Open access314 authors 19 Oct 2017 12

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.