Science Explorer Back to mapMap
Discussion
Institution · Adaptimmune (United Kingdom)

Most cited papers from Adaptimmune (United Kingdom)

Adaptimmune (United Kingdom)

What are the most cited papers from Adaptimmune (United Kingdom)?

The most cited paper from Adaptimmune (United Kingdom) is "Cardiovascular toxicity and titin cross-reactivity of affinity-enhanced T cells in myeloma and melanoma" (Gerald P. Linette et al., 2013), with 1,200 citations. Next come "NY-ESO-1–specific TCR–engineered T cells mediate sustained antigen-specific antitumor effects in myeloma" (863) and "Identification of a Titin-Derived HLA-A1–Presented Peptide as a Cross-Reactive Target for Engineered MAGE A3–Directed T Cells" (700).

Showing 50 of 60 papers. Every paper with more than 19 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 Cardiovascular toxicity and titin cross-reactivity of affinity-enhanced T cells in myeloma and melanoma Gerald P. Linette et al. · Blood Open access 14 Jun 2013 1,200
2 NY-ESO-1–specific TCR–engineered T cells mediate sustained antigen-specific antitumor effects in myeloma Aaron P. Rapoport et al. · Nature Medicine Open access 20 Jul 2015 863
3 Identification of a Titin-Derived HLA-A1–Presented Peptide as a Cross-Reactive Target for Engineered MAGE A3–Directed T Cells Brian Cameron et al. · Science Translational Medicine Open access 7 Aug 2013 700
4 Safety and Clinical Activity of Pembrolizumab and Multisite Stereotactic Body Radiotherapy in Patients With Advanced Solid Tumors Jason J. Luke, Jeffrey M. Lemons, Theodore G Karrison et al. · Journal of Clinical Oncology Open access 13 Feb 2018 597
5 Antitumor Activity Associated with Prolonged Persistence of Adoptively Transferred NY-ESO-1 c259T Cells in Synovial Sarcoma Sandra P. D’Angelo et al. · Cancer Discovery Open access 11 Jun 2018 444
6 Afamitresgene autoleucel for advanced synovial sarcoma and myxoid round cell liposarcoma (SPEARHEAD-1): an international, open-label, phase 2 trial Sandra P. D’Angelo et al. · The Lancet Open access 27 Mar 2024 290
7 Tebentafusp, A TCR/Anti-CD3 Bispecific Fusion Protein Targeting gp100, Potently Activated Antitumor Immune Responses in Patients with Metastatic Melanoma Mark Ross Middleton, Cheryl McAlpine, Victoria K. Woodcock et al. · Clinical Cancer Research Open access 18 Aug 2020 282
8 Control of HIV-1 immune escape by CD8 T cells expressing enhanced T-cell receptor Angel Varela‐Rohena, Peter E. Molloy, Steven Mark Dunn et al. · Nature Medicine Open access 9 Nov 2008 244
9 Incidence, Prevalence, and Survival of Patients with Idiopathic Pulmonary Fibrosis in the UK Helen Strongman, Imran Kausar, Toby M. Maher · Advances in Therapy Open access 11 Apr 2018 240
10 The SCAR‐3 study: 5‐year adhesion‐related readmission risk following lower abdominal surgical procedures Mike C. Parker, Malcolm S. Wilson, Donald Menzies et al. · Colorectal Disease Jul 2005 221
11 Autologous T cell therapy for MAGE-A4+ solid cancers in HLA-A*02+ patients: a phase 1 trial David S. Hong et al. · Nature Medicine Open access 2023 206
12 Current Concepts and New Trends in the Diagnosis and Management of Recurrent Miscarriage Jaume Alijotas‐Reig, Carmen Garrido‐Giménez · Obstetrical & Gynecological Survey 23 May 2013 187
13 Systemic and local immunity following adoptive transfer of NY-ESO-1 SPEAR T cells in synovial sarcoma Indu Ramachandran et al. · Journal for ImmunoTherapy of Cancer Open access 24 Oct 2019 147
14 T cell receptor binding affinity governs the functional profile of cancer-specific CD8+ T cells Maw Pin Tan, Andrew B. Gerry, Jared Brewer et al. · Clinical & Experimental Immunology Open access 15 Dec 2014 139
15 Single-cell multiplexed cytokine profiling of CD19 CAR-T cells reveals a diverse landscape of polyfunctional antigen-specific response Qiong Xue, Emily Bettini, Patrick Paczkowski et al. · Journal for ImmunoTherapy of Cancer Open access 24 Oct 2017 131
16 Preclinical evaluation of an affinity-enhanced MAGE-A4-specific T-cell receptor for adoptive T-cell therapy Joseph P. Sanderson, Darragh Crowley, Guy E. Wiedermann et al. · OncoImmunology Open access 24 Nov 2019 97
17 Efficacy of N-Acetylcysteine in the Treatment of Nicotine Dependence: A Double-Blind Placebo-Controlled Pilot Study Lianne Schmaal, Lotte Berk, Kai P. Hulstijn et al. · European Addiction Research Open access 2011 95
18 Colorectal surgery: the risk and burden of adhesion‐related complications Mike Parker, Malcolm S. Wilson, Don Menzies et al. · Colorectal Disease Nov 2004 92
19 Long-term safety and activity of NY-ESO-1 SPEAR T cells after autologous stem cell transplant for myeloma Edward Allen Stadtmauer, Thomas H. Faitg, Daniel E. Lowther et al. · Blood Advances Open access 9 Jul 2019 91
20 Fludarabine and neurotoxicity in engineered T-cell therapy Kate L. Lowe, Crystal Lee Mackall, Elliot Norry et al. · Gene Therapy Open access 7 May 2018 87
21 An approved in vitro approach to preclinical safety and efficacy evaluation of engineered T cell receptor anti-CD3 bispecific (ImmTAC) molecules Jane V. Harper et al. · PLoS ONE Open access 15 Oct 2018 84
22 The MEK inhibitor selumetinib complements CTLA-4 blockade by reprogramming the tumor immune microenvironment Edmund Poon, Stefanie Mullins, Amanda Watkins et al. · Journal for ImmunoTherapy of Cancer Open access 24 Jul 2017 77
23 Genetic programming of macrophages generates an in vitro model for the human erythroid island niche Martha Lopez‐Yrigoyen, Cheng-Tao Yang, A Fidanza et al. · Nature Communications Open access 20 Feb 2019 69
24 Affinity-enhanced T-cell receptors for adoptive T-cell therapy targeting MAGE-A10: strategy for selection of an optimal candidate E.C. Border, Joseph P. Sanderson, Thomas Weissensteiner et al. · OncoImmunology Open access 20 Nov 2018 69
25 Cardiac toxicity secondary to long term treatment with chloroquine Álvaro Cervera, G ESPINOSA, R CERVERA et al. · Annals of the Rheumatic Diseases Open access Mar 2001 64
26 A Randomized Trial of Concurrent Smoking-Cessation and Substance Use Disorder Treatment in Stimulant-Dependent Smokers Theresa M. Winhusen et al. · The Journal of Clinical Psychiatry Open access 9 Dec 2013 64
27 β-Lactam Antibiotics Form Distinct Haptenic Structures on Albumin and Activate Drug-Specific T-Lymphocyte Responses in Multiallergic Patients with Cystic Fibrosis Rosalind E. Jenkins, Fiazia S. Yaseen, Manal M. Monshi et al. · Chemical Research in Toxicology 14 May 2013 56
28 Examining the presentation of tumor-associated antigens on peptide-pulsed T2 cells Giovanna Bossi, Andrew B. Gerry, Samantha J. Paston et al. · OncoImmunology Open access Nov 2013 56
29 Phase I clinical trial evaluating the safety and efficacy of ADP-A2M10 SPEAR T cells in patients with MAGE-A10+ advanced non-small cell lung cancer George R. Blumenschein et al. · Journal for ImmunoTherapy of Cancer Open access 2022 55
30 TCR affinity and specificity requirements for human regulatory T-cell function Gabriela Plesa, Lingjie Zheng, Andrew R. Medvec et al. · Blood Open access 8 Feb 2012 54
31 Tuning T‐Cell Receptor Affinity to Optimize Clinical Risk‐Benefit When Targeting Alpha‐Fetoprotein–Positive Liver Cancer Roslin Y. Docta, Tiago Ferronha, Joseph P. Sanderson et al. · Hepatology Open access 18 Dec 2018 53
32 Histone Deacetylase Inhibitors Enhance CD4 T Cell Susceptibility to NK Cell Killing but Reduce NK Cell Function Matthew J. Pace, James P. Williams, Ayako Kurioka et al. · PLoS Pathogens Open access 16 Aug 2016 52
33 Replicative aging is associated with loss of genetic heterogeneity from extrachromosomal circular DNA in Saccharomyces cerevisiae Iñigo Prada-Luengo, Henrik Devitt Møller, Rasmus Amund Henriksen et al. · Nucleic Acids Research Open access 17 Jun 2020 50
34 The diagnostic work-up of cancer-associated myositis Albert Selva-O’Callaghan, Xavier Martínez‐Gómez, Ernesto Trallero Araguás et al. · Current Opinion in Rheumatology Open access 30 Jun 2018 50
35 T cells targeting NY-ESO-1 demonstrate efficacy against disseminated neuroblastoma Nathan Singh, Irina M. Kulikovskaya, David M. Barrett et al. · OncoImmunology Open access 12 Aug 2015 45
36 Development of thermo-responsive polycaprolactone macrocarriers conjugated with Poly(N-isopropyl acrylamide) for cell culture Linh T. B. Nguyen, Akinlolu Oyekunle Oluseun Odeleye, Chih–Yao Chui et al. · Scientific Reports Open access 5 Mar 2019 38
37 Oral Delivery of Biologics via the Intestine Roger R. C. New · Pharmaceutics Open access 24 Dec 2020 36
38 Short-term administration of JAK2 inhibitors reduces splenomegaly in mouse models of β-thalassemia intermedia and major Carla Casu, Vania Lo Presti, Paraskevi Rea Oikonomidou et al. · Haematologica Open access 2 Nov 2017 36
39 Reverse micelle-encapsulated recombinant baculovirus as an oral vaccine against H5N1 infection in mice Mookkan Prabakaran, Selvaraj Madhan, Nayana Prabhu et al. · Antiviral Research 13 Feb 2010 36
40 Human leucocyte antigen class I-redirected anti-tumour CD4+ T cells require a higher T cell receptor binding affinity for optimal activity than CD8+ T cells Maw Pin Tan, Garry M. Dolton, Andrew B. Gerry et al. · Clinical & Experimental Immunology Open access 21 Jun 2016 34
41 Squalene-adjuvanted H7N9 virus vaccine induces robust humoral immune response against H7N9 and H7N7 viruses Chia-Ying Wu, Ching‐Yuan Chang, Hsiu‐Hua Ma et al. · Vaccine Open access 21 Jun 2014 33
42 Structural and Functional Changes of the Invariant NKT Clonal Repertoire in Early Rheumatoid Arthritis Salah Mansour, Anna S. Tocheva, Joseph P. Sanderson et al. · The Journal of Immunology Open access 10 Nov 2015 33
43 A Report from a Workshop of the International Stem Cell Banking Initiative, Held in Collaboration of Global Alliance for iPSC Therapies and the Harvard Stem Cell Institute, Boston, 2017 Jung‐Hyun Kim et al. · Stem Cells Open access 25 Apr 2019 29
44 The Tumor Targeted Superantigen ABR-217620 Selectively Engages TRBV7-9 and Exploits TCR-pMHC Affinity Mimicry in Mediating T Cell Cytotoxicity Gunnar Hedlund, Helena Eriksson, Anette Sundstedt et al. · PLoS ONE Open access 23 Oct 2013 29
45 Quantum wavefront shaping with a 48-element programmable phase plate for electrons Chu-Ping Yu, Francisco Vega Ibáñez, Armand Béché et al. · SciPost Physics Open access 4 Dec 2023 28
46 Increased serum levels of soluble l -selectin (CD62L) in patients with active systemic lupus erythematosus (SLE) Josep Font, P Pizcueta, Manuel Ramos‐Casals et al. · Clinical & Experimental Immunology Open access 2000 27
47 Crowdsourced Protein Design: Lessons From the Adaptyv EGFR Binder Competition Tudor‐Stefan Cotet et al. · bioRxiv (Cold Spring Harbor Laboratory) PreprintOpen access 23 Apr 2025 26
48 Specific support needs and experiences of carers of people with frontotemporal dementia: A systematic review Sara Tookey, Caroline V. Greaves, Jonathan Daniel Rohrer et al. · Dementia ReviewOpen access 11 Jun 2021 26
49 Inhibition of HIV Virus by Neutralizing Vhh Attached to Dual Functional Liposomes Encapsulating Dapivirine Scarlet Xiaoyan Wang, Johan Míchiels, Kevin K. Ariën et al. · Nanoscale Research Letters Open access 27 Jul 2016 26
50 Reduced ADAMTS13 activity is associated with thrombotic risk in systemic lupus erythematosus Susana Martin‐Rodriguez, Joan Carles Reverter, Dolors Tàssies et al. · Lupus 29 Mar 2015 26

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.