Science Explorer Back to mapMap

Most cited papers from Advanced Cancer Therapeutics

What are the most cited papers from Advanced Cancer Therapeutics?

The most cited paper from Advanced Cancer Therapeutics is "Phase II Trial of Curcumin in Patients with Advanced Pancreatic Cancer" (Navneet Kaur Dhillon, Bharat Bhushan Aggarwal, Robert Alan Newman et al., 2008), with 1,333 citations. Next come "Autophagy as a target for anticancer therapy" (816) and "Rapid Akt activation by nicotine and a tobacco carcinogen modulates the phenotype of normal human airway epithelial cells" (511).

Showing 50 of 59 papers. Every paper with more than 53 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 Phase II Trial of Curcumin in Patients with Advanced Pancreatic Cancer Navneet Kaur Dhillon, Bharat Bhushan Aggarwal, Robert Alan Newman et al. · Clinical Cancer Research 15 Jul 2008 1,333
2 Autophagy as a target for anticancer therapy Filip Jankú, David James McConkey, David S. Hong et al. · Nature Reviews Clinical Oncology Review 17 May 2011 816
3 Rapid Akt activation by nicotine and a tobacco carcinogen modulates the phenotype of normal human airway epithelial cells Kip A. West, John Brognard, Amy Sanders Clark et al. · Journal of Clinical Investigation Open access 2003 511
4 Curcumin (diferuloylmethane) alters the expression profiles of microRNAs in human pancreatic cancer cells Michael G. Sun, Zeev E. Estrov, Yuan Ji et al. · Molecular Cancer Therapeutics Open access Mar 2008 412
5 Phase II Study of Taxol, Merbarone, and Piroxantrone in Stage IV Non-Small-Cell Lung Cancer: The Eastern Cooperative Oncology Group Results Alex Y. C. Chang, K. Kim, John H. Glick et al. · JNCI Journal of the National Cancer Institute 3 Mar 1993 339
6 The PTEN/MMAC1/TEP tumor suppressor gene decreases cell growth and induces apoptosis and anoikis in breast cancer cells Yiling Lu, Yue-Zhen Lin, Ruth LaPushin et al. · Oncogene 25 Nov 1999 338
7 Randomized Phase III Intergroup Trial of Isotretinoin to Prevent Second Primary Tumors in Stage I Non-Small-Cell Lung Cancer Scott Michael Lippman, J. J. Lee, Daniel D. Karp et al. · JNCI Journal of the National Cancer Institute 18 Apr 2001 321
8 Eye Injuries Associated with Anesthesia A Closed Claims Analysis William M. Gild, Karen L. Posner, Robert A. Caplan et al. · Anesthesiology Open access Feb 1992 291
9 Targeting 6-Phosphofructo-2-Kinase (PFKFB3) as a Therapeutic Strategy against Cancer Brian F. Clem, Julie O’Neal, Gilles H. Tapolsky et al. · Molecular Cancer Therapeutics Open access 15 May 2013 279
10 Richter syndrome Apostolia Maria Tsimberidou, Michael J. Keating · Cancer Open access Dec 2004 276
11 Characterizing the patterns of clonal selection in circulating tumor DNA from patients with colorectal cancer refractory to anti-EGFR treatment Maria Pia Morelli, Michael James Overman, Arvind N. Dasari et al. · Annals of Oncology Open access 28 Jan 2015 256
12 Targeted therapy in non-small-cell lung cancer—is it becoming a reality? Filip Jankú, David J. Stewart, Razelle Kurzrock · Nature Reviews Clinical Oncology Review 15 Jun 2010 251
13 Clinical Development of 17-Allylamino, 17-Demethoxygeldanamycin Edward A. Sausville, Joseph E. Tomaszewski, Percy S. Ivy · Current Cancer Drug Targets Oct 2003 226
14 PIK3CA Mutations Frequently Coexist with RAS and BRAF Mutations in Patients with Advanced Cancers Filip Jankú, J. Jack Lee, Apostolia Maria Tsimberidou et al. · PLoS ONE Open access 29 Jul 2011 204
15 Phase II trial of docetaxel (Taxotere) in patients with adenocarcinoma of the upper gastrointestinal tract previously untreated with cytotoxic chemotherapy: the Eastern Cooperative Oncology Group (ECOG) Results of Protocol E1293 Avi I. Einzig, Donna S Neuberg, Scot C. Remick et al. · Medical Oncology Jun 1996 197
16 Differentiation patterns in the blastic phase of chronic myeloid leukemia. James D. Griffin, Robert F. Todd, Jerome Ritz et al. · PubMed 1983 196
17 A Novel, Macrophage Migration Inhibitory Factor Suicide Substrate Inhibits Motility and Growth of Lung Cancer Cells Millicent G. Winner, Jason B. Meier, Swen Zierow et al. · Cancer Research Open access 14 Sep 2008 168
18 Phase I Study of Epigenetic Modulation with 5-Azacytidine and Valproic Acid in Patients with Advanced Cancers Fadi Braiteh, Andres O. Soriano, Guillermo Garcia‐Manero et al. · Clinical Cancer Research Open access 30 Sep 2008 166
19 The Dose Response of Caudal Morphine in Children Elliot J. Krane, Donald C. Tyler, Lawrence Jacobson · Anesthesiology Open access Jul 1989 158
20 Therapeutic targeting of PFKFB3 with a novel glycolytic inhibitor PFK158 promotes lipophagy and chemosensitivity in gynecologic cancers Susmita Mondal, Debarshi Roy, Sayantani Sarkar Bhattacharya et al. · International Journal of Cancer Open access 18 Sep 2018 156
21 Effect of Equiosmolar Solutions of Mannitol versus Hypertonic Saline on Intraoperative Brain Relaxation and Electrolyte Balance Irene Rozet, Nuj Tontisirin, Saipin L. Muangman et al. · Anesthesiology Nov 2007 151
22 Tumor-infiltrating lymphocytes, breast cancer subtypes and therapeutic efficacy Sherene Loi · OncoImmunology Open access Jul 2013 146
23 Liposomal vincristine in relapsed non-Hodgkin's lymphomas: Early results of an ongoing phase II trial A H Sarris, Frederick B. Hagemeister, Jorge Enrique Romaguera et al. · Annals of Oncology Open access 2000 143
24 Deciphering the molecular and biologic processes that mediate histone deacetylase inhibitor–induced thrombocytopenia Mark J. Bishton, Simon James Harrison, Benjamin P. Martin et al. · Blood Open access 4 Feb 2011 139
25 Activity of Docetaxel in Platinum-Treated Non–Small-Cell Lung Cancer: Results of a Phase II Multicenter Trial David R. Gandara, Everett E. Vokes, Mark A. Green et al. · Journal of Clinical Oncology 2000 135
26 Regulation of PRMT5–MDM4 axis is critical in the response to CDK4/6 inhibitors in melanoma Shatha AbuHammad et al. · Proceedings of the National Academy of Sciences Open access 22 Aug 2019 129
27 Eradication of solid tumors using histone deacetylase inhibitors combined with immune-stimulating antibodies Ailsa J. Christiansen, Alison C. West, Kellie-Marie Banks et al. · Proceedings of the National Academy of Sciences Open access 22 Feb 2011 116
28 Single-Nucleotide Polymorphism (SNP) Analysis in the ABC Half-Transporter ABCG2 (MXR/BCRP/ABCP1) Yasumasa Honjo, Kuniaki Morisaki, Lyn Mickley Huff et al. · Cancer Biology & Therapy Open access Nov 2002 116
29 The natural history of fludarabine-refractory chronic lymphocytic leukemia patients who fail alemtuzumab or have bulky lymphadenopathy Constantine Si Lun Tam, Susan Mary O'Brien, Susan A. Lerner et al. · Leukemia & lymphoma/Leukemia and lymphoma 2007 98
30 Body Composition, Symptoms, and Survival in Advanced Cancer Patients Referred to a Phase I Service Henrique Afonseca Parsons, Vickie Elaine Baracos, Navjot Dhillon et al. · PLoS ONE Open access 3 Jan 2012 97
31 Prognostic Indicators and Treatment Outcome in 94 Cases of Fibrolamellar Hepatocellular Carcinoma Ahmed Omar Kaseb, Mohamed Shama, İbrahim Halil Şahin et al. · Oncology Open access 2013 96
32 BRAF Mutations in Advanced Cancers: Clinical Characteristics and Outcomes Hazem Edmond El-Osta, Gerald Steven Falchook, Apostolia Maria Tsimberidou et al. · PLoS ONE Open access 19 Oct 2011 94
33 Safety of Chronic Intrathecal Morphine Infusion in a Sheep Model Tamara Lee Gradert, Wallace B. Baze, William C. Satterfield et al. · Anesthesiology Jul 2003 89
34 Immunoneutralization of gonadotropin-releasing hormone type-III suppresses male reproductive behavior of cichlids Satoshi Ogawa, Go Akiyama, Shumei Kato et al. · Neuroscience Letters 20 Jun 2006 88
35 The ubiquitin-specific protease USP2a enhances tumor progression by targeting cyclin A1 in bladder cancer Jayoung Kim, Wun‐Jae Kim, Zhiqian Liu et al. · Cell Cycle Open access 15 Mar 2012 87
36 The anticancer effects of HDAC inhibitors require the immune system Alison C. West, Mark John Smyth, Ricky W. Johnstone · OncoImmunology Open access 2014 87
37 RET Fusion as a Novel Driver of Medullary Thyroid Carcinoma Elizabeth Gardner Grubbs, Patrick Kwok‐Shing Ng, Jacquelin H. Bui et al. · The Journal of Clinical Endocrinology & Metabolism Open access 29 Dec 2014 83
38 Phase I Trial of a Combination of the Multikinase Inhibitor Sorafenib and the Farnesyltransferase Inhibitor Tipifarnib in Advanced Malignancies David S. Hong, Saı̈d M. Sebti, Robert Alan Newman et al. · Clinical Cancer Research Open access 11 Nov 2009 81
39 Richter’s Transformation in Chronic Lymphocytic Leukemia Apostolia Maria Tsimberidou, Michael J. Keating · Seminars in Oncology Apr 2006 79
40 Enhanced shedding of extracellular vesicles from amoeboid prostate cancer cells Jayoung Kim, Samantha Morley, Minh T. N. Le et al. · Cancer Biology & Therapy Open access 14 Jan 2014 79
41 Evolving role of ribonucleoside reductase inhibitors in hematologic malignancies Apostolia Maria Tsimberidou, Yesid Alvarado, Francis Joseph Giles · Expert Review of Anticancer Therapy Aug 2002 77
42 Microbial contamination of hematopoietic progenitor cell grafts—incidence, clinical outcome, and cost‐effectiveness: an analysis of 735 grafts Rammurti T. Kamble, Shubham Pant, George Basil Selby et al. · Transfusion 31 May 2005 75
43 Survival of patients in a Phase 1 clinic Jennifer J. Wheler, Apostolia Maria Tsimberidou, David S. Hong et al. · Cancer Open access 22 Jan 2009 75
44 C-Met Inhibitor MK-8003 Radiosensitizes c-Met–Expressing Non–Small-Cell Lung Cancer Cells With Radiation-Induced c-Met–Expression Vikas Bhardwaj, Yanai Zhan, María Angélica Cortez et al. · Journal of Thoracic Oncology Open access 22 May 2012 73
45 β1 integrin Grant A. Howe, Christina Addison · Cell Adhesion & Migration Open access Mar 2012 68
46 Pediatric Therapy-related Myelodysplastic Syndrome/Acute Myeloid Leukemia Dolly G. Aguilera, Christos Vaklavas, Apostolia Maria Tsimberidou et al. · Journal of Pediatric Hematology/Oncology 29 Oct 2009 64
47 Comprehensive Genomic Profiling of Clinically Advanced Medullary Thyroid Carcinoma Andreas M. F. Heilmann et al. · Oncology Open access 2016 63
48 An Association Between the Risk of Cancer and Mutations in the HRAS1 Minisatellite Locus Theodore G. Krontiris, Bernie Devlin, Daniel D. Karp · Diagnostic Molecular Pathology Sep 1994 63
49 Evidence of a role for the novel zinc-finger transcription factor ZKSCAN3 in modulating Cyclin D2 expression in multiple myeloma Lin Yang, H. Wang, Steven Mitchell Kornblau et al. · Oncogene Open access 8 Nov 2010 63
50 Functional Differences Between Monocyte Chemotactic Protein-1 Receptor A and Monocyte Chemotactic Protein-1 Receptor B Expressed in a Jurkat T Cell Sheila K. Sanders, Sheila M. Crean, Peter A. Boxer et al. · The Journal of Immunology Nov 2000 60

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.