Most cited papers from Advanced Pharma

Advanced Pharma

What are the most cited papers from Advanced Pharma?

The most cited paper from Advanced Pharma is "A Randomized, Placebo-Controlled Trial of Zoledronic Acid in Patients With Hormone-Refractory Metastatic Prostate Carcinoma" (Fred Saad, Donald M. Gleason, Robin M. Murray et al., 2002), with 1,663 citations. Next come "Activated Ras requires autophagy to maintain oxidative metabolism and tumorigenesis" (1,337) and "Long-term management of moderate-to-severe atopic dermatitis with dupilumab and concomitant topical corticosteroids (LIBERTY AD CHRONOS): a 1-year, randomised, double-blinded, placebo-controlled, phase 3 trial" (1,269).

Published TypeFieldAccessCitations

Showing 50 of 60 papers. Every paper with more than 124 citations is listed.

Most cited papers, sortable by citations and release date
#	Paper
1	A Randomized, Placebo-Controlled Trial of Zoledronic Acid in Patients With Hormone-Refractory Metastatic Prostate Carcinoma Fred Saad, Donald M. Gleason, Robin M. Murray et al. · JNCI Journal of the National Cancer Institute	Oct 2002	1,663
2	Activated Ras requires autophagy to maintain oxidative metabolism and tumorigenesis Jessie Yanxiang Guo, Hsin-Yi Chen, Robin Mathew et al. · Genes & Development Open access	11 Feb 2011	1,337
3	Long-term management of moderate-to-severe atopic dermatitis with dupilumab and concomitant topical corticosteroids (LIBERTY AD CHRONOS): a 1-year, randomised, double-blinded, placebo-controlled, phase 3 trial Andrew Blauvelt et al. · The Lancet Open access	4 May 2017	1,269
4	4th ESO–ESMO International Consensus Guidelines for Advanced Breast Cancer (ABC 4) Fátima Cardoso et al. · Annals of Oncology Open access	23 May 2018	1,202
5	Factors Affecting Open-Set Word Recognition in Adults With Cochlear Implants Laura K. Holden, Charles C. Finley, Jill B. Firszt et al. · Ear and Hearing Open access	24 Jan 2013	990
6	Identification of HE1 as the Second Gene of Niemann-Pick C Disease Saule Naureckiene, David E. Sleat, Henry Lackland et al. · Science	22 Dec 2000	834
7	The Rel/NF-κB Family Directly Activates Expression of the Apoptosis Inhibitor Bcl-x L Cailin Chen, Leonard C. Edelstein, Céline Gélinas · Molecular and Cellular Biology Open access	Apr 2000	759
8	A luminal epithelial stem cell that is a cell of origin for prostate cancer Xi Wang, Marianna Kruithof‐de Julio, Kyriakos D. Economides et al. · Nature Open access	Sep 2009	748
9	To be, or not to be: NF-κB is the answer – role of Rel/NF-κB in the regulation of apoptosis Jérôme Kucharczak, Matthew J Simmons, Yongjun Fan et al. · Oncogene	8 Dec 2003	746
10	Crystal structure of HIV‐1 reverse transcriptase in complex with a polypurine tract RNA:DNA Stefan G. Sarafianos, Kalyan Kumar Das, Chris Tantillo et al. · The EMBO Journal Open access	15 Mar 2001	410
11	High-resolution structures of HIV-1 reverse transcriptase/TMC278 complexes: Strategic flexibility explains potency against resistance mutations Kalyan Kumar Das, Joseph D. Bauman, Arthur D. Clark et al. · Proceedings of the National Academy of Sciences Open access	30 Jan 2008	342
12	ESO-ESMO 2nd international consensus guidelines for advanced breast cancer (ABC2) Fátima Cardoso et al. · The Breast Open access	20 Sep 2014	339
13	An efficient triple resonance experiment using carbon-13 isotropic mixing for determining sequence-specific resonance assignments of isotopically-enriched proteins Gaetano Thomas Montelione, Barbara A. Lyons, S. Donald Emerson et al. · Journal of the American Chemical Society	Dec 1992	320
14	DNA damage response and MCL-1 destruction initiate apoptosis in adenovirus-infected cells Andrea Cuconati, Chandreyee Mukherjee, Denise Perez et al. · Genes & Development Open access	2003	315
15	Plasticity in patterns of histone modifications and chromosomal proteins in Drosophila heterochromatin Nicole C. Riddle, Aki Minoda, Peter V. Kharchenko et al. · Genome Research Open access	22 Dec 2010	303
16	Suppression of NF-κB and NF-κB-regulated gene expression by sulforaphane and PEITC through IκBα, IKK pathway in human prostate cancer PC-3 cells Changjiang Xu, Guoxiang Shen, Chi Chen et al. · Oncogene	18 Apr 2005	301
17	Structure of HIV-1 RT/TIBO R 86183 complex reveals similarity in the binding of diverse nonnucleoside inhibitors Jianping Ding, Kalyan Kumar Das, Henri Moereels et al. · Nature Structural & Molecular Biology	May 1995	299
18	Structure of unliganded HIV-1 reverse transcriptase at 2.7 å resolution: implications of conformational changes for polymerization and inhibition mechanisms Y. Hsiou, Jianping Ding, Kalyan Kumar Das et al. · Structure Open access	Jul 1996	287
19	Deep learning-based survival prediction for multiple cancer types using histopathology images Ellery Wulczyn, David F. Steiner, Zhaoyang Xu et al. · PLoS ONE Open access	17 Jun 2020	280
20	The Hepatitis B Virus Polymerase Mutation rtV173L Is Selected during Lamivudine Therapy and Enhances Viral Replication In Vitro William E. Delaney, Huiling Yang, Christopher E. Westland et al. · Journal of Virology Open access	13 Oct 2003	261
21	3rd ESO–ESMO international consensus guidelines for Advanced Breast Cancer (ABC 3) Fátima Cardoso et al. · The Breast Open access	5 Dec 2016	234
22	Btf, a Novel Death-Promoting Transcriptional Repressor That Interacts with Bcl-2-Related Proteins Gary M. Kasof, Lakshmi Goyal, Eileen White · Molecular and Cellular Biology Open access	Jun 1999	233
23	Association of Bax and Bak Homo-oligomers in Mitochondria Valery M. Mikhailov, Margarita Mikhailova, Kurt Degenhardt et al. · Journal of Biological Chemistry Open access	Feb 2003	226
24	Structural basis for suppression of a host antiviral response by influenza A virus Kalyan Kumar Das, Li-Chung Ma, Rong Xiao et al. · Proceedings of the National Academy of Sciences Open access	25 Aug 2008	223
25	Dual Roles of Cripto as a Ligand and Coreceptor in the Nodal Signaling Pathway Yu‐Ting Yan, Jan-Jan Liu, Yi Luo et al. · Molecular and Cellular Biology Open access	Jul 2002	214
26	Human hepatocytes: Isolation, cryopreservation and applications in drug development Albert P. Li · Chemico-Biological Interactions	10 Jan 2007	204
27	Modulation of p53-Mediated Transcriptional Repression and Apoptosis by the Adenovirus E1B 19K Protein Peter Sabbatini, Shiun‐Kwei Chiou, Lakshmi Rao et al. · Molecular and Cellular Biology Open access	Feb 1995	191
28	Clinical effectiveness of an acellular dermal regenerative tissue matrix compared to standard wound management in healing diabetic foot ulcers: a prospective, randomised, multicentre study Alexander M. Reyzelman, Ryan T. Crews, John Christopher Moore et al. · International Wound Journal Open access	2 Apr 2009	189
29	Structure of HIV-1 reverse transcriptase/DNA complex at 7 Å resolution showing active site locations Eddy Arnold, Alfredo Jacobo‐Molina, Raymond G. Nanni et al. · Nature	May 1992	187
30	Influence of remaining coronal tooth structure location on the fracture resistance of restored endodontically treated anterior teeth Clarisse C. H. Ng, Herman B. Dumbrigue, Manal I. Al‐Bayat et al. · Journal of Prosthetic Dentistry	Apr 2006	176
31	The COVID-19 pandemic and research shutdown: staying safe and productive M. Bishr Omary, Jeetendra R. Eswaraka, S. David Kimball et al. · Journal of Clinical Investigation Open access	3 Apr 2020	172
32	An overview of recent progress in dental applications of zinc oxide nanoparticles Hedaiat Moradpoor, Mohsen Safaei, Hamid Reza Mozaffari et al. · RSC Advances Open access	2021	171
33	Intracranial Delivery of CLN2 Reduces Brain Pathology in a Mouse Model of Classical Late Infantile Neuronal Ceroid Lipofuscinosis Marco A. Passini, James C. Dodge, Jie Bu et al. · Journal of Neuroscience Open access	Feb 2006	171
34	A randomized trial of short-course ciprofloxacin, ofloxacin, or trimethoprim/sulfamethoxazole for the treatment of acute urinary tract infection in women James M McCarty, George J. Richard, Werner Huck et al. · The American Journal of Medicine	Mar 1999	169
35	Targeting Brd4 for cancer therapy: inhibitors and degraders Ying‐Chao Duan, Yuanyuan Guan, Wenping Qin et al. · MedChemComm Open access	2018	167
36	Model Appropriateness and Population Pharmacokinetic Modeling Ene Ette, Paul J. Williams, Yong Ho Kim et al. · The Journal of Clinical Pharmacology	Jun 2003	166
37	All Brn3 genes can promote retinal ganglion cell differentiation in the chick Wei Liu, Suvarna L. Khare, Xuelian Liang et al. · Development	Aug 2000	164
38	Insights into DNA Polymerization Mechanisms from Structure and Function Analysis of HIV-1 Reverse Transcriptase Premal H. Patel, Alfredo Jacobo‐Molina, Jianping Ding et al. · Biochemistry	25 Apr 1995	164
39	Structures of HIV-1 RT–DNA complexes before and after incorporation of the anti-AIDS drug tenofovir Steve Tuske, Stefan G. Sarafianos, Arthur D. Clark et al. · Nature Structural & Molecular Biology	21 Apr 2004	162
40	Current Profile of Adults Presenting for Preoperative Cochlear Implant Evaluation Jourdan Taylor Holder, Susan M. Reynolds, Linsey W. Sunderhaus et al. · Trends in Hearing Open access	2018	158
41	Loss-of-Function of Nkx3.1 Promotes Increased Oxidative Damage in Prostate Carcinogenesis Xuesong Ouyang, Theodore L. DeWeese, William G. Nelson et al. · Cancer Research	Aug 2005	155
42	A Mouse Model of Classical Late-Infantile Neuronal Ceroid Lipofuscinosis Based on Targeted Disruption of the CLN2 Gene Results in a Loss of Tripeptidyl-Peptidase I Activity and Progressive Neurodegeneration David E. Sleat, Jennifer A. Wiseman, Mukarram El-Banna et al. · Journal of Neuroscience Open access	13 Oct 2004	150
43	Design of potent selective zinc-mediated serine protease inhibitors Bradley A. Katz, James Matthew Clark, Janet Sue Finer-Moore et al. · Nature Open access	Feb 1998	150
44	c-Myc induces apoptosis in epithelial cells by both p53-dependent and p53-independent mechanisms. Daitoku Sakamuro, Valerie T. Eviner, Katherine J. Elliott et al. · PubMed	7 Dec 1995	148
45	Activator Protein-1 Transcription Factors Are Associated with Progression and Recurrence of Prostate Cancer Xuesong Ouyang, Walter J. Jessen, Hikmat A Al‐Ahmadie et al. · Cancer Research	Apr 2008	145
46	Transforming Growth Factor-β-inducible Phosphorylation of Smad3 Guannan Wang, Isao Matsuura, Dongming He et al. · Journal of Biological Chemistry Open access	14 Feb 2009	145
47	Human homologues of yeast helicase Jian Lu, Janet R. Mullen, Steven J. Brill et al. · Nature	Oct 1996	142
48	Explaining Variability in Tacrolimus Pharmacokinetics to Optimize Early Exposure in Adult Kidney Transplant Recipients Rogier R. Press, Bart A. Ploeger, Jan den Hartigh et al. · Therapeutic Drug Monitoring	Apr 2009	142
49	Combinatorial activities of Akt and B-Raf/Erk signaling in a mouse model of androgen-independent prostate cancer Hui Gao, Xuesong Ouyang, Whitney A Banach-Petrosky et al. · Proceedings of the National Academy of Sciences Open access	14 Sep 2006	139
50	Genetic Basis for Activity Differences Between Vancomycin and Glycolipid Derivatives of Vancomycin Ulrike Eggert, Natividad Ruiz, Brian V. Falcone et al. · Science	12 Oct 2001	139

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.