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Most cited papers from Affymax (United States)

What are the most cited papers from Affymax (United States)?

The most cited paper from Affymax (United States) is "Initial sequencing and comparative analysis of the mouse genome" (Asif T. Chinwalla et al., 2002), with 7,343 citations. Next come "Light-Directed, Spatially Addressable Parallel Chemical Synthesis" (2,705) and "RNA Maps Reveal New RNA Classes and a Possible Function for Pervasive Transcription" (2,615).

Showing 50 of 60 papers. Every paper with more than 119 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 Initial sequencing and comparative analysis of the mouse genome Asif T. Chinwalla et al. · Nature Open access223 authors Dec 2002 7,343
2 Light-Directed, Spatially Addressable Parallel Chemical Synthesis Stephen P. A. Fodor, Jill Read, Michael C. Pirrung et al. · Science 15 Feb 1991 2,705
3 RNA Maps Reveal New RNA Classes and a Possible Function for Pervasive Transcription Philipp Kapranov et al. · Science 18 May 2007 2,615
4 Rapid evolution of a protein in vitro by DNA shuffling Willem P.C. Stemmer · Nature Aug 1994 1,949
5 DNA shuffling by random fragmentation and reassembly: in vitro recombination for molecular evolution. Willem PC Stemmer · Proceedings of the National Academy of Sciences Open access 25 Oct 1994 1,298
6 Improved Green Fluorescent Protein by Molecular Evolution Using DNA Shuffling Andreas Crameri, Erik A. Whitehorn, Emily H. Tate et al. · Nature Biotechnology Mar 1996 1,207
7 Applications of Combinatorial Technologies to Drug Discovery. 2. Combinatorial Organic Synthesis, Library Screening Strategies, and Future Directions Eric M. Gordon, Ronald W. Barrett, William J. Dower et al. · Journal of Medicinal Chemistry May 1994 1,147
8 Applications of Combinatorial Technologies to Drug Discovery. 1. Background and Peptide Combinatorial Libraries Mark A. Gallop, Ronald W. Barrett, William J. Dower et al. · Journal of Medicinal Chemistry Open access Apr 1994 1,136
9 Peroxisome Proliferator-activated Receptors α and γ Are Activated by Indomethacin and Other Non-steroidal Anti-inflammatory Drugs Jürgen M. Lehmann, James M. Lenhard, Beverly B. Oliver et al. · Journal of Biological Chemistry Open access Feb 1997 1,115
10 Cloning the P. falciparum gene encoding PfEMP1, a malarial variant antigen and adherence receptor on the surface of parasitized human erythrocytes Dror I. Baruch, Britten L. Pasloske, Hardeep B. Singh et al. · Cell Open access Jul 1995 1,058
11 MDCK (Madin-Darby Canine Kidney) Cells: A Tool for Membrane Permeability Screening Jennifer D. Irvine, Lori H. Takahashi, Karen Lockhart et al. · Journal of Pharmaceutical Sciences 1999 988
12 Peptides on phage: a vast library of peptides for identifying ligands. Steven E. Cwirla, Elizabeth A. Peters, Ronald W. Barrett et al. · Proceedings of the National Academy of Sciences Open access Aug 1990 934
13 A minimal peptide substrate in biotin holoenzyme synthetase‐catalyzed biotinylation Dorothy Beckett, Elena G. Kovaleva, Peter J. Schatz · Protein Science Open access 1999 759
14 Single-step assembly of a gene and entire plasmid from large numbers of oligodeoxyribonucleotides Willem P.C. Stemmer, Andreas Crameri, Kim D. Ha et al. · Gene Oct 1995 738
15 Multiplexed biochemical assays with biological chips Stephen P. A. Fodor, Richard P. Rava, Xiaohua C. Huang et al. · Nature Aug 1993 737
16 Functional Mimicry of a Protein Hormone by a Peptide Agonist: The EPO Receptor Complex at 2.8 Å Oded Livnah, Enrico Adriano Stura, Dana L. Johnson et al. · Science 26 Jul 1996 593
17 Use of Peptide Libraries to Map the Substrate Specificity of a Peptide-Modifying Enzyme: A 13 Residue Consensus Peptide Specifies Biotinylation in Escherichia coli Peter J. Schatz · Nature Biotechnology Oct 1993 592
18 Recombination-mediated PCR-directed plasmid construction in vivo in yeast Kevin R. Oldenburg · Nucleic Acids Research Open access 15 Jan 1997 540
19 Novel RNAs Identified From an In-Depth Analysis of the Transcriptome of Human Chromosomes 21 and 22 Dione Kampa, Jill Cheng, Philipp Kapranov et al. · Genome Research Open access Mar 2004 528
20 An in vitro polysome display system for identifying ligands from very large peptide libraries. Larry C. Mattheakis, Ramesh R. Bhatt, William J. Dower · Proceedings of the National Academy of Sciences Open access 13 Sep 1994 514
21 Plasmodium falciparum erythrocyte membrane protein 1 is a parasitized erythrocyte receptor for adherence to CD36, thrombospondin, and intercellular adhesion molecule 1. Dror I. Baruch, J A Gormely, C Ma et al. · Proceedings of the National Academy of Sciences Open access 16 Apr 1996 411
22 The interplay of matrix metalloproteinases, morphogens and growth factors is necessary for branching of mammary epithelial cells Marina Simian, Yohei Hirai, Marc Navre et al. · Development Open access 15 Aug 2001 395
23 Prediction of Human Intestinal Absorption of Drug Compounds from Molecular Structure Matthew D. Wessel, Peter C. Jurs, John W. Tolan et al. · Journal of Chemical Information and Computer Sciences 19 Jun 1998 367
24 An Unnatural Biopolymer Charles Y. Cho, Edmund J. Moran, Sara R. Cherry et al. · Science 3 Sep 1993 365
25 Light-dependent herbicides: an overview F. Dan Hess · Weed Science Mar 2000 362
26 Generation and screening of an oligonucleotide-encoded synthetic peptide library. Michael C. Needels, David Gareth Jones, Emily H. Tate et al. · Proceedings of the National Academy of Sciences Open access 15 Nov 1993 344
27 Toward cell–targeting gene therapy vectors: Selection of cell–binding peptides from random peptide–presenting phage libraries Michael A. Barry, William J. Dower, Stephen Albert Johnston · Nature Medicine Mar 1996 342
28 A peroxisome proliferator-activated receptor γ ligand inhibits adipocyte differentiation Jennifer L. Oberfield, Jon L. Collins, Christopher P. Holmes et al. · Proceedings of the National Academy of Sciences Open access 25 May 1999 320
29 Peptide ligands for a sugar-binding protein isolated from a random peptide library. Kevin R. Oldenburg, Duraikkannu Loganathan, Irwin Goldstein et al. · Proceedings of the National Academy of Sciences Open access 15 Jun 1992 281
30 Peptide binding consensus of the NHE‐RF‐PDZ1 domain matches the C‐terminal sequence of cystic fibrosis transmembrane conductance regulator (CFTR) Shusheng Wang, Ronald W. Raab, Peter J. Schatz et al. · FEBS Letters Open access May 1998 279
31 Directed evolution of a fucosidase from a galactosidase by DNA shuffling and screening Ji-Hu Zhang, Glenn N. Dawes, Willem P.C. Stemmer · Proceedings of the National Academy of Sciences Open access 29 Apr 1997 276
32 Strategy and Tactics in Combinatorial Organic Synthesis. Applications to Drug Discovery Eric M. Gordon, Mark A. Gallop, Dinesh V. Patel · Accounts of Chemical Research Open access 13 Mar 1996 269
33 PDZ domain of neuronal nitric oxide synthase recognizes novel C-terminal peptide sequences Nicole L. Stricker, Karen S. Christopherson, B. Alexander Yi et al. · Nature Biotechnology Apr 1997 259
34 Model Studies for Newo-Nitrobenzyl Photolabile Linkers: Substituent Effects on the Rates of Photochemical Cleavage Christopher P. Holmes · The Journal of Organic Chemistry Apr 1997 253
35 Identification of a Region of PfEMP1 That Mediates Adherence of Plasmodium falciparum Infected Erythrocytes to CD36: Conserved Function With Variant Sequence Dror I. Baruch, Xin C. Ma, Hardeep B. Singh et al. · Blood Nov 1997 252
36 Approaches to Combinatorial Synthesis of Heterocycles: A Solid-Phase Synthesis of 1,4-Dihydropyridines Mikhail Fedorovich Gordeev, Dinesh V. Patel, Eric M. Gordon · The Journal of Organic Chemistry 1996 251
37 A new cytokine-receptor binding mode revealed by the crystal structure of the IL-1 receptor with an antagonist Herman Schreuder, Chantal Tardif, Susanne Trump-Kallmeyer et al. · Nature Mar 1997 249
38 Global Transcriptional Response of Bacillus subtilis to Heat Shock John D. Helmann, Ming‐Fang Wu, Phil A. Kobel et al. · Journal of Bacteriology 15 Dec 2001 242
39 The Global Transcriptional Response ofBacillus subtilisto Peroxide Stress Is Coordinated by Three Transcription Factors John D. Helmann, Ming‐Fang Wu, Ahmed Gaballa et al. · Journal of Bacteriology Open access 16 Dec 2002 236
40 Development and preliminary evaluation of a 90 K Axiom® SNP array for the allo-octoploid cultivated strawberry Fragaria × ananassa Nahla Victor Bassil et al. · BMC Genomics Open access 5 Mar 2015 207
41 Dynamic model based algorithms for screening and genotyping over 100K SNPs on oligonucleotide microarrays X. Di, Hideo Matsuzaki, T. A. Webster et al. · Computer applications in the biosciences Open access 18 Jan 2005 194
42 Defining the Bacillus subtilis σW regulon: a comparative analysis of promoter consensus search, run-off transcription/macroarray analysis (ROMA), and transcriptional profiling approaches Min Cao, Phil A. Kobel, Maud M Morshedi et al. · Journal of Molecular Biology Feb 2002 191
43 Pharmacophore Fingerprinting. 1. Application to QSAR and Focused Library Design Malcolm J. McGregor, Steven M. Muskal · Journal of Chemical Information and Computer Sciences 19 Mar 1999 187
44 TNFα-Mediated Inhibition and Reversal of Adipocyte Differentiation Is Accompanied by Suppressed Expression of PPARγ without Effects on Pref-1 Expression* Hong Yun Xing, Jeffrey P. Northrop, Jeffrey Grove et al. · Endocrinology Jul 1997 187
45 Molecular evolution of an arsenate detoxification pathway by DNA shuffling Andreas Crameri, Glenn N. Dawes, Emilio Rodrı́guez et al. · Nature Biotechnology May 1997 179
46 Screening for receptor ligands using large libraries of peptides linked to the C terminus of the lac repressor. Millard G. Cull, Jeff F. Miller, Peter J. Schatz · Proceedings of the National Academy of Sciences Open access Mar 1992 177
47 A New Series of Estrogen Receptor Modulators That Display Selectivity for Estrogen Receptor β Brad R. Henke, Thomas G. Consler, Ning Fei Go et al. · Journal of Medicinal Chemistry Open access 26 Oct 2002 161
48 Solid-Supported Combinatorial Synthesis of Structurally Diverse β-Lactams Béatrice Ruhland, Ashok Bhandari, Eric M. Gordon et al. · Journal of the American Chemical Society 1996 161
49 A Peptide-Based Erythropoietin-Receptor Agonist for Pure Red-Cell Aplasia Iain C. Macdougall, Jérôme Rossert, Nicole Casadevall et al. · New England Journal of Medicine Open access 4 Nov 2009 157
50 Potent Peptide Analogues of a G Protein Receptor-binding Region Obtained with a Combinatorial Library Edith L. Martin, Stephanie Rens‐Domiano, Peter J. Schatz et al. · Journal of Biological Chemistry Open access 1996 157

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.