| 1 |
A map of human genome variation from population-scale sequencing
Richard M. Durbin et al. · Nature
Open access337 authors |
26 Oct 2010 |
8,156 |
| 2 |
A cross-platform toolkit for mass spectrometry and proteomics
Matthew Chambers et al. · Nature Biotechnology
Open access |
Oct 2012 |
4,457 |
| 3 |
The RIN: an RNA integrity number for assigning integrity values to RNA measurements
Andreas Schröeder, Odilo Mueller, Susanne Stocker et al. · BMC Molecular Biology
Open access |
31 Jan 2006 |
2,717 |
| 4 |
Integration of biological networks and gene expression data using Cytoscape
Melissa Cline et al. · Nature Protocols
Open access |
27 Sep 2007 |
2,601 |
| 5 |
The MicroArray Quality Control (MAQC) project shows inter- and intraplatform reproducibility of gene expression measurements
Leming M. Shi et al. · Nature Biotechnology
Open access138 authors |
Sep 2006 |
2,178 |
| 6 |
Targeted capture and massively parallel sequencing of 12 human exomes
Sarah Boon Hsi Ng, Emily H. Turner, Peggy D. Robertson et al. · Nature
Open access |
16 Aug 2009 |
2,073 |
| 7 |
lincRNAs act in the circuitry controlling pluripotency and differentiation
Mitchell Guttman, Julie Donaghey, Bryce W. Carey et al. · Nature
Open access |
26 Aug 2011 |
1,913 |
| 8 |
The genome sequence of the rice blast fungus Magnaporthe grisea
Ralph A. Dean et al. · Nature
Open access |
Apr 2005 |
1,707 |
| 9 |
Solution hybrid selection with ultra-long oligonucleotides for massively parallel targeted sequencing
Andreas Gnirke, Alexandre Melnikov, Jared Maguire et al. · Nature Biotechnology
Open access |
Feb 2009 |
1,530 |
| 10 |
Expression profiling using microarrays fabricated by an ink-jet oligonucleotide synthesizer
Timothy R. Hughes et al. · Nature Biotechnology
|
Apr 2001 |
1,301 |
| 11 |
PD-L1 Immunohistochemistry Assays for Lung Cancer: Results from Phase 1 of the Blueprint PD-L1 IHC Assay Comparison Project
Fred R. Hirsch et al. · Journal of Thoracic Oncology
Open access |
29 Nov 2016 |
1,274 |
| 12 |
Towards practical, high-capacity, low-maintenance information storage in synthesized DNA
Nick Goldman, Paul Bertone, Siyuan Chen et al. · Nature
Open access |
22 Jan 2013 |
1,260 |
| 13 |
The DNA-encoded nucleosome organization of a eukaryotic genome
Noam Kaplan, Irene K. Moore, Yvonne N. Fondufe‐Mittendorf et al. · Nature
Open access |
17 Dec 2008 |
1,260 |
| 14 |
Polycomb-mediated methylation on Lys27 of histone H3 pre-marks genes for de novo methylation in cancer
Yeshayahu Schlesinger, Ravid Straussman, Ilana Keshet et al. · Nature Genetics
|
31 Dec 2006 |
1,245 |
| 15 |
Chemically modified guide RNAs enhance CRISPR-Cas genome editing in human primary cells
Ayal Hendel, Rasmus Otkjær Bak, Joseph T. Clark et al. · Nature Biotechnology
Open access |
29 Jun 2015 |
1,159 |
| 16 |
Mapping and sequencing of structural variation from eight human genomes
Jeffrey M. Kidd et al. · Nature
Open access |
30 Apr 2008 |
1,157 |
| 17 |
Targeted and genome-scale strategies reveal gene-body methylation signatures in human cells
Mad Price Ball, Jin Billy Li, Yuan Gao et al. · Nature Biotechnology
Open access |
29 Mar 2009 |
1,124 |
| 18 |
Mapping long-range promoter contacts in human cells with high-resolution capture Hi-C
Borbála Mifsud, Filipe Tavares-Cadete, Alice Young et al. · Nature Genetics
|
4 May 2015 |
1,101 |
| 19 |
Etch rates for micromachining processing-part II
K.R. Williams, Kapil Gupta, Matthew Wasilik · Journal of Microelectromechanical Systems
|
Dec 2003 |
1,030 |
| 20 |
Promiscuous Mutations Activate the Noncanonical NF-κB Pathway in Multiple Myeloma
Jonathan J. Keats et al. · Cancer Cell
Open access |
Aug 2007 |
991 |
| 21 |
An inhibitor of oxidative phosphorylation exploits cancer vulnerability
Jennifer R. Molina et al. · Nature Medicine
Open access |
8 Jun 2018 |
981 |
| 22 |
In-plane heterostructures of graphene and hexagonal boron nitride with controlled domain sizes
Zheng Liu, Lulu Ma, Gang Shi et al. · Nature Nanotechnology
|
27 Jan 2013 |
936 |
| 23 |
3′ UTR seed matches, but not overall identity, are associated with RNAi off-targets
Amanda Birmingham, Emily M. Anderson, Angela Reynolds et al. · Nature Methods
|
17 Feb 2006 |
925 |
| 24 |
The MicroArray Quality Control (MAQC)-II study of common practices for the development and validation of microarray-based predictive models
Leming M. Shi et al. · Nature Biotechnology
Open access201 authors |
30 Jul 2010 |
922 |
| 25 |
mzML—a Community Standard for Mass Spectrometry Data
Lennart Martens, Matthew Chambers, Marc Sturm et al. · Molecular & Cellular Proteomics
Open access |
17 Aug 2010 |
804 |
| 26 |
Discovering Motifs in Ranked Lists of DNA Sequences
Eran Eden, Doron Lipson, Sivan Yogev et al. · PLoS Computational Biology
Open access |
21 Mar 2007 |
771 |
| 27 |
Image classification for content-based indexing
Aditya Vailaya, Mário A. T. Figueiredo, Anil Kumar Jain et al. · IEEE Transactions on Image Processing
|
2001 |
762 |
| 28 |
Tissue Classification with Gene Expression Profiles
Amir Ben‐Dor, Laurakay Bruhn, Nir Friedman et al. · Journal of Computational Biology
|
Aug 2000 |
745 |
| 29 |
Imaging the body with diffuse optical tomography
David A. Boas, Dana H. Brooks, Eric L. Miller et al. · IEEE Signal Processing Magazine
|
2001 |
725 |
| 30 |
Ultrathin high-temperature oxidation-resistant coatings of hexagonal boron nitride
Zheng Liu, Yongji Gong, Wu Zhou et al. · Nature Communications
Open access |
4 Oct 2013 |
723 |
| 31 |
Diversity of Human Copy Number Variation and Multicopy Genes
Peter H. Sudmant, Jacob Otto Kitzman, Francesca Antonacci et al. · Science
Open access |
28 Oct 2010 |
720 |
| 32 |
Fate Tracing Reveals the Endothelial Origin of Hematopoietic Stem Cells
Ann C. Zovein, Jennifer J. Hofmann, Maureen R. Lynch et al. · Cell stem cell
Open access |
Dec 2008 |
707 |
| 33 |
IEEE 1588 standard for a precision clock synchronization protocol for networked measurement and control systems
John C. Eidson, Kang Lee
Conference paper |
2002 |
705 |
| 34 |
Evaluation of quantitative miRNA expression platforms in the microRNA quality control (miRQC) study
Pieter Mestdagh et al. · Nature Methods
|
29 Jun 2014 |
657 |
| 35 |
Gene expression analysis reveals matrilysin as a key regulator of pulmonary fibrosis in mice and humans
Fengrong Zuo, Naftali Kaminski, Elsie M. Eugui et al. · Proceedings of the National Academy of Sciences
Open access |
30 Apr 2002 |
634 |
| 36 |
Short interfering RNAs can induce unexpected and divergent changes in the levels of untargeted proteins in mammalian cells
Peter C. Scacheri, Orit Rozenblatt–Rosen, Natasha J. Caplen et al. · Proceedings of the National Academy of Sciences
Open access |
9 Feb 2004 |
614 |
| 37 |
26 Tbit s−1 line-rate super-channel transmission utilizing all-optical fast Fourier transform processing
D. Hillerkuss et al. · Nature Photonics
|
22 May 2011 |
587 |
| 38 |
An Interlaboratory Evaluation of Drift Tube Ion Mobility–Mass Spectrometry Collision Cross Section Measurements
Sarah M. Stow, Tim J. Causon, Xueyun Zheng et al. · Analytical Chemistry
Open access |
Aug 2017 |
563 |
| 39 |
Modified Butterworth-Van Dyke circuit for FBAR resonators and automated measurement system
John D. Larson, Paul D. Bradley, Scott A. Wartenberg et al.
Conference paper |
2000 |
562 |
| 40 |
Large Expression Differences in Genes for Iron and Zinc Homeostasis, Stress Response, and Lignin Biosynthesis Distinguish Roots of Arabidopsis thaliana and the Related Metal Hyperaccumulator Thlaspi caerulescens
Judith E. van de Mortel, Laia Almar Villanueva, Henk Schat et al. · PLANT PHYSIOLOGY
Open access |
22 Sep 2006 |
550 |
| 41 |
Discovering Local Structure in Gene Expression Data: The Order-Preserving Submatrix Problem
Amir Ben‐Dor, Benny Chor, Richard M. Karp et al. · Journal of Computational Biology
|
Jun 2003 |
546 |
| 42 |
Genome-Wide Identification of Human RNA Editing Sites by Parallel DNA Capturing and Sequencing
Jin Billy Li, Erez Y. Levanon, Jung-Ki Yoon et al. · Science
|
28 May 2009 |
540 |
| 43 |
Inferring gene regulatory logic from high-throughput measurements of thousands of systematically designed promoters
Eilon Sharon, Yael Kalma, Ayala Sharp et al. · Nature Biotechnology
Open access |
20 May 2012 |
532 |
| 44 |
Amino Acid Analysis by Capillary Electrophoresis Electrospray Ionization Mass Spectrometry
Tomoyoshi Soga, David N. Heiger · Analytical Chemistry
|
18 Feb 2000 |
529 |
| 45 |
TCR–peptide–MHC interactions in situ show accelerated kinetics and increased affinity
Johannes B. Huppa, Markus Axmann, Manuel A. Mörtelmaier et al. · Nature
Open access |
Feb 2010 |
525 |
| 46 |
The pluripotent regulatory circuitry connecting promoters to their long-range interacting elements
Stefan Schoenfelder et al. · Genome Research
Open access |
9 Mar 2015 |
519 |
| 47 |
An Investigation of the Mechanisms of Electronic Sensing of Protein Adsorption on Carbon Nanotube Devices
Robert Jeenchen Chen, Hee Cheul Choi, Sarunya Bangsaruntip et al. · Journal of the American Chemical Society
|
15 Jan 2004 |
519 |
| 48 |
Performance comparison of one-color and two-color platforms within the Microarray Quality Control (MAQC) project
Tucker A. Patterson, Edward K. Lobenhofer, Stephanie Fulmer-Smentek et al. · Nature Biotechnology
|
Sep 2006 |
515 |
| 49 |
Global proteomic profiling of phosphopeptides using electron transfer dissociation tandem mass spectrometry
Henrik Molina, David M. Horn, Ning Tang et al. · Proceedings of the National Academy of Sciences
Open access |
7 Feb 2007 |
508 |
| 50 |
Cyclops
Mohammad Hossein Rahimi, Rick Baer, Obimdinachi I. Iroezi et al.
Conference paper |
2 Nov 2005 |
507 |