Most cited papers from AiCuris (Germany)

AiCuris (Germany)

What are the most cited papers from AiCuris (Germany)?

The most cited paper from AiCuris (Germany) is "Letermovir for Cytomegalovirus Prophylaxis in Hematopoietic-Cell Transplantation" (Roy F. Chemaly, Andrew J. Ullmann, Susanne Stoelben et al., 2014), with 375 citations. Next come "The Novel Anticytomegalovirus Compound AIC246 (Letermovir) Inhibits Human Cytomegalovirus Replication through a Specific Antiviral Mechanism That Involves the Viral Terminase" (344) and "Definitions of Resistant and Refractory Cytomegalovirus Infection and Disease in Transplant Recipients for Use in Clinical Trials" (247).

Published TypeFieldAccessCitations

Showing 50 of 61 papers. Every paper with more than 36 citations is listed.

Most cited papers, sortable by citations and release date
#	Paper
1	Letermovir for Cytomegalovirus Prophylaxis in Hematopoietic-Cell Transplantation Roy F. Chemaly, Andrew J. Ullmann, Susanne Stoelben et al. · New England Journal of Medicine Open access	7 May 2014	375
2	The Novel Anticytomegalovirus Compound AIC246 (Letermovir) Inhibits Human Cytomegalovirus Replication through a Specific Antiviral Mechanism That Involves the Viral Terminase Thomas Goldner, Guy Hewlett, Nicole Ettischer et al. · Journal of Virology Open access	13 Jul 2011	344
3	Definitions of Resistant and Refractory Cytomegalovirus Infection and Disease in Transplant Recipients for Use in Clinical Trials Roy F. Chemaly, Sunwen Chou, Hermann Einsele et al. · Clinical Infectious Diseases Open access	17 Aug 2018	247
4	In Vitro and In Vivo Activities of the Novel Anticytomegalovirus Compound AIC246 Peter Lischka, Guy Hewlett, Tobias Wunberg et al. · Antimicrobial Agents and Chemotherapy Open access	5 Jan 2010	241
5	Structures of ClpP in complex with acyldepsipeptide antibiotics reveal its activation mechanism Byung‐Gil Lee, Eun Young Park, Kyung-Eun Lee et al. · Nature Structural & Molecular Biology	19 Mar 2010	235
6	The antibiotic ADEP reprogrammes ClpP, switching it from a regulated to an uncontrolled protease Janine Kirstein, Anja Hoffmann, Hauke Lilie et al. · EMBO Molecular Medicine Open access	26 Mar 2009	233
7	Antibiotic acyldepsipeptides activate ClpP peptidase to degrade the cell division protein FtsZ Peter Saß, Michaele Josten, Kirsten Famulla et al. · Proceedings of the National Academy of Sciences Open access	3 Oct 2011	197
8	Helicase–Primase Inhibitor Pritelivir for HSV-2 Infection Anna Wald, Lawrence Corey, Burkhard Timmler et al. · New England Journal of Medicine	15 Jan 2014	173
9	No Association of Abacavir Use With Myocardial Infarction Xiao Xia Ding, Eugenio Andraca‐Carrera, Charles K. Cooper et al. · JAIDS Journal of Acquired Immune Deficiency Syndromes	Dec 2012	161
10	First Report of Successful Treatment of Multidrug-Resistant Cytomegalovirus Disease with the Novel Anti-CMV Compound AIC246 Daniel R. Kaul, Susanne Stoelben, Eric Cober et al. · American Journal of Transplantation Open access	26 Apr 2011	161
11	Systematic Identification of Selective Essential Genes in Helicobacter pylori by Genome Prioritization and Allelic Replacement Mutagenesis Alison F. Chalker, Heather W. Minehart, Nicky J. Hughes et al. · Journal of Bacteriology Open access	15 Feb 2001	157
12	Analysis of the Mechanism of Action of Potent Antibacterial Hetero-tri-organometallic Compounds: A Structurally New Class of Antibiotics Michaela Wenzel, Malay Patra, Christoph Helmut Rudi Senges et al. · ACS Chemical Biology	11 Apr 2013	155
13	AAA+ chaperones and acyldepsipeptides activate the ClpP protease via conformational control Malte Gersch, Kirsten Famulla, Maria Dahmen et al. · Nature Communications Open access	19 Feb 2015	145
14	Oncocin (VDKPPYLPRPRPPRRIYNR-NH2): A Novel Antibacterial Peptide Optimized against Gram-Negative Human Pathogens Daniel Knappe, Stefania Piantavigna, Anne Maria Kaldal Hansen et al. · Journal of Medicinal Chemistry	21 Jun 2010	139
15	Preemptive treatment of Cytomegalovirus infection in kidney transplant recipients with letermovir: results of a Phase 2a study Susanne Stoelben, Wolfgang Arns, Lutz Renders et al. · Transplant International	24 Oct 2013	137
16	The Innovative Medicines Initiative's New Drugs for Bad Bugs programme: European public–private partnerships for the development of new strategies to tackle antibiotic resistance Tomislav Kostyanev, Marc J. M. Bonten, Seamus O’Brien et al. · Journal of Antimicrobial Chemotherapy Open access	15 Nov 2015	129
17	Crossing the barrier: Evolution and spread of a major class of mosaic pbp2x in Streptococcus pneumoniae, S. mitis and S. oralis Chi Fang, Oliver Nolte, Carina Bergmann et al. · International Journal of Medical Microbiology	25 Apr 2007	129
18	How many modes of action should an antibiotic have? Heike Brötz‐Oesterhelt, Nina A. Brunner · Current Opinion in Pharmacology	31 Jul 2008	126
19	Structural variations of the cell wall precursor lipid II in Gram-positive bacteria — Impact on binding and efficacy of antimicrobial peptides Daniela Münch, Hans‐Georg Sahl · Biochimica et Biophysica Acta (BBA) - Biomembranes Open access	2 May 2015	124
20	Characterization of Cytomegalovirus Breakthrough Events in a Phase 2 Prophylaxis Trial of Letermovir (AIC246, MK 8228) Peter Lischka, Detlef Michel, Holger Zimmermann · The Journal of Infectious Diseases	25 Jun 2015	116
21	In Vitro Evaluation of the Activities of the Novel Anticytomegalovirus Compound AIC246 (Letermovir) against Herpesviruses and Other Human Pathogenic Viruses Manfred Marschall, Thomas Stamminger, Andreas Urban et al. · Antimicrobial Agents and Chemotherapy Open access	22 Nov 2011	116
22	HSV antivirals – current and future treatment options Alexander Birkmann, Holger Zimmermann · Current Opinion in Virology Review	19 Feb 2016	115
23	Api88 Is a Novel Antibacterial Designer Peptide To Treat Systemic Infections with Multidrug-Resistant Gram-Negative Pathogens Patricia Czihal, Daniel Knappe, Stefanie Fritsche et al. · ACS Chemical Biology	17 May 2012	112
24	Effect of Pritelivir Compared With Valacyclovir on Genital HSV-2 Shedding in Patients With Frequent Recurrences Anna Wald, Burkhard Timmler, Amalia Magaret et al. · JAMA Open access	20 Dec 2016	109
25	The intrinsic resistome ofPseudomonas aeruginosato β-lactams Carolina Alvarez‐Ortega, Irith Wiegand, Jorge Olivares‐Pacheco et al. · Virulence Open access	Mar 2011	109
26	Geno- and Phenotypic Characterization of Human Cytomegalovirus Mutants Selected In Vitro after Letermovir (AIC246) Exposure Thomas Goldner, Christine Hempel, Helga Ruebsamen‐Schaeff et al. · Antimicrobial Agents and Chemotherapy Open access	4 Nov 2013	108
27	Vascular and pharmacokinetic effects of EndoTAG-1 in patients with advanced cancer and liver metastasis Ulrike Fasol, Annette Frost, Martin Büchert et al. · Annals of Oncology Open access	22 Jun 2011	104
28	Novel Apidaecin 1b Analogs with Superior Serum Stabilities for Treatment of Infections by Gram-Negative Pathogens Nicole Berthold, Patricia Czihal, Stefanie Fritsche et al. · Antimicrobial Agents and Chemotherapy Open access	Nov 2012	103
29	Acyldepsipeptide antibiotics kill mycobacteria by preventing the physiological functions of the ClpP1P2 protease Kirsten Famulla, Peter Saß, Imran T. Malik et al. · Molecular Microbiology Open access	26 Feb 2016	93
30	Medicinal Chemistry Optimization of Acyldepsipeptides of the Enopeptin Class Antibiotics Berthold Hinzen, Siegfried Raddatz, Holger Paulsen et al. · ChemMedChem	14 Jun 2006	91
31	Rational Design of Oncocin Derivatives with Superior Protease Stabilities and Antibacterial Activities Based on the High‐Resolution Structure of the Oncocin‐DnaK Complex Daniel Knappe, Michael Zahn, Ute Sauer et al. · ChemBioChem	8 Mar 2011	89
32	Pharmacokinetics and Safety of Letermovir Coadministered With Cyclosporine A or Tacrolimus in Healthy Subjects Dirk Kropeit, Oliver von Richter, Hans‐Peter Stobernack et al. · Clinical Pharmacology in Drug Development	2 Oct 2017	83
33	Investigational drugs to treat methicillin-resistantStaphylococcus aureus Cuong Vuong, Anthony J. Yeh, Gordon Y. C. Cheung et al. · Expert Opinion on Investigational Drugs Open access	4 Nov 2015	80
34	Risk Factors for Treatment Failure and Mortality Among Hospitalized Patients With Complicated Urinary Tract Infection: A Multicenter Retrospective Cohort Study (RESCUING Study Group) Noa Eliakim‐Raz et al. · Clinical Infectious Diseases Open access	11 May 2018	77
35	Towards early inclusion of children in tuberculosis drugs trials: a consensus statement Sharon Nachman et al. · The Lancet Infectious Diseases Open access	6 May 2015	77
36	Predictive factors for multidrug-resistant gram-negative bacteria among hospitalised patients with complicated urinary tract infections Aina Gomila Grange, Evelyn Shaw, Jordi Carratalà et al. · Antimicrobial Resistance and Infection Control Open access	14 Sep 2018	76
37	Cost of hospitalised patients due to complicated urinary tract infections: a retrospective observational study in countries with high prevalence of multidrug-resistant Gram-negative bacteria: the COMBACTE-MAGNET, RESCUING study Laura Vallejo‐Torres, Miquel Pujol, Evelyn Shaw et al. · BMJ Open Open access	Apr 2018	76
38	Antiviral strategies to combat cytomegalovirus infections in transplant recipients Peter Lischka, H.-J. Zimmermann · Current Opinion in Pharmacology	26 Aug 2008	75
39	A novel screening strategy to identify ABCB1 substrates and inhibitors Oliver von Richter, Hristos Glavinas, Péter Krajcsi et al. · Naunyn-Schmiedeberg s Archives of Pharmacology	28 Aug 2008	69
40	The designer proline-rich antibacterial peptide A3-APO is effective against systemic Escherichia coli infections in different mouse models Dóra Szabó, Eszter Ostorházi, Annegret Binas et al. · International Journal of Antimicrobial Agents	24 Dec 2009	67
41	Discovery, Chemistry, and Preclinical Development of Pritelivir, a Novel Treatment Option for Acyclovir-Resistant Herpes Simplex Virus Infections Alexander Birkmann, Susanne Bonsmann, Dirk Kropeit et al. · Journal of Medicinal Chemistry Open access	6 Oct 2022	55
42	Clinical outcomes of hospitalised patients with catheter-associated urinary tract infection in countries with a high rate of multidrug-resistance: the COMBACTE-MAGNET RESCUING study on behalf of RESCUING Study Group and Study Sites, Aina Gomila Grange, Jordi Carratalà et al. · Antimicrobial Resistance and Infection Control Open access	Dec 2019	55
43	Risk factors and prognosis of complicated urinary tract infections caused by Pseudomonas aeruginosa in hospitalized patients: a retrospective multicenter cohort study A Gomila, Jordi Carratalà, Noa Eliakim‐Raz et al. · Infection and Drug Resistance Open access	Dec 2018	53
44	Mutual Interplay between the Human Cytomegalovirus Terminase Subunits pUL51, pUL56, and pUL89 Promotes Terminase Complex Formation Sebastian Neuber, Karen M Wagner, Thomas Goldner et al. · Journal of Virology Open access	30 Mar 2017	52
45	Superior Efficacy of Helicase-Primase Inhibitor BAY 57–1293 for Herpes Infection and Latency in the Guinea Pig Model of Human Genital Herpes Disease Judith Baumeister, Ruediger Fischer, Peter Eckenberg et al. · Antiviral chemistry & chemotherapy	Feb 2007	52
46	Mandatory surveillance and outbreaks reporting of the WHO priority pathogens for research & discovery of new antibiotics in European countries Nithya Babu Rajendran, Nico T. Mutters, Giuseppe Marasca et al. · Clinical Microbiology and Infection Open access	5 Dec 2019	50
47	Novel non-heteroarylpyrimidine (HAP) capsid assembly modifiers have a different mode of action from HAPs in vitro Angelica Corcuera, Katharina Stolle, Stefan Hillmer et al. · Antiviral Research Open access	20 Jul 2018	50
48	Structure and Total Synthesis of Lysobactin (Katanosin B) Franz von Nussbaum, Sonja Anlauf, Jordi Benet‐Buchholz et al. · Angewandte Chemie International Edition	9 Jan 2007	50
49	Inhibition of protein kinase C phosphorylation of hepatitis B virus capsids inhibits virion formation and causes intracellular capsid accumulation Linda Wittkop, Alexandra Schwarz, Aurélia Cassany et al. · Cellular Microbiology Open access	26 Jan 2010	50
50	Expression of the transporter encoded by the cefT gene of Acremonium chrysogenum increases cephalosporin production in Penicillium chrysogenum Jeroen G. Nijland, Andriy Kovalchuk, Marco A. van den Berg et al. · Fungal Genetics and Biology	23 Jul 2008	49

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.