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Bortezomib, thalidomide, and dexamethasone with or without daratumumab before and after autologous stem-cell transplantation for newly diagnosed multiple myeloma (CASSIOPEIA): a randomised, open-label, phase 3 study
Philippe Moreau et al. · The Lancet
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3 Jun 2019 |
973 |
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Vertebroplasty versus conservative treatment in acute osteoporotic vertebral compression fractures (Vertos II): an open-label randomised trial
Caroline A. H. Klazen et al. · The Lancet
Open access |
10 Aug 2010 |
911 |
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Association Between Administration of IL-6 Antagonists and Mortality Among Patients Hospitalized for COVID-19
The WHO Rapid Evidence Appraisal for COVID-19 Therapies (REACT) Working Group et al. · JAMA
Open access353 authors |
6 Jul 2021 |
732 |
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A prospective validation of the HEART score for chest pain patients at the emergency department
Barbra E. Backus, A. Jacob Six, Johannes C. Kelder et al. · International Journal of Cardiology
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7 Mar 2013 |
590 |
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Active Surveillance for Low-Risk Prostate Cancer Worldwide: The PRIAS Study
Meelan Bul, Xiaoye Zhu, R. Valdagni et al. · European Urology
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12 Nov 2012 |
545 |
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Association of Axial Length With Risk of Uncorrectable Visual Impairment for Europeans With Myopia
J. Willem L. Tideman, Margaretha C. C. Snabel, Milly S. Tedja et al. · JAMA Ophthalmology
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20 Oct 2016 |
441 |
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Autologous haematopoietic stem-cell transplantation versus bortezomib–melphalan–prednisone, with or without bortezomib–lenalidomide–dexamethasone consolidation therapy, and lenalidomide maintenance for newly diagnosed multiple myeloma (EMN02/HO95): a multicentre, randomised, open-label, phase 3 study
Michèle Cavo et al. · The Lancet Haematology
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30 Apr 2020 |
387 |
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Exhaled Breath Profiling Enables Discrimination of Chronic Obstructive Pulmonary Disease and Asthma
Niki Fens, Aeilko Having Zwinderman, Marc P. van der Schee et al. · American Journal of Respiratory and Critical Care Medicine
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27 Aug 2009 |
365 |
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The Preventive Antibiotics in Stroke Study (PASS): a pragmatic randomised open-label masked endpoint clinical trial
Willeke F. Westendorp et al. · The Lancet
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19 Jan 2015 |
339 |
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Randomized clinical trial of observational versus antibiotic treatment for a first episode of CT-proven uncomplicated acute diverticulitis
Lidewine Daniels et al. · British journal of surgery
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30 Sep 2016 |
329 |
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Preoperative MRI and surgical management in patients with nonpalpable breast cancer: The MONET – Randomised controlled trial
Nicky H. G. M. Peters, Stijn van Esser, Maurice A. A. J. van den Bosch et al. · European Journal of Cancer
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31 Dec 2010 |
325 |
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Bisoprolol and Fluvastatin for the Reduction of Perioperative Cardiac Mortality and Myocardial Infarction in Intermediate-Risk Patients Undergoing Noncardiovascular Surgery
Martin Dunkelgrün, Eric H. Boersma, Olaf Schouten et al. · Annals of Surgery
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Jun 2009 |
307 |
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Prehospital antibiotics in the ambulance for sepsis: a multicentre, open label, randomised trial
Nadia Alam et al. · The Lancet Respiratory Medicine
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29 Nov 2017 |
293 |
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Thin-cap fibroatheroma predicts clinical events in diabetic patients with normal fractional flow reserve: the COMBINE OCT–FFR trial
Elvin Kedhi et al. · European Heart Journal
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25 Jun 2021 |
288 |
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Procalcitonin-guided decision making for duration of antibiotic therapy in neonates with suspected early-onset sepsis: a multicentre, randomised controlled trial (NeoPIns)
Martin Stocker et al. · The Lancet
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13 Jul 2017 |
279 |
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A randomized phase 3 study on the effect of thalidomide combined with adriamycin, dexamethasone, and high-dose melphalan, followed by thalidomide maintenance in patients with multiple myeloma
Henk M. Lokhorst et al. · Blood
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30 Oct 2009 |
279 |
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COVID-19 severity and mortality in patients with chronic lymphocytic leukemia: a joint study by ERIC, the European Research Initiative on CLL, and CLL Campus
Lydia Scarfò et al. · Leukemia
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9 Jul 2020 |
276 |
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Daratumumab plus bortezomib and dexamethasone versus bortezomib and dexamethasone in relapsed or refractory multiple myeloma: updated analysis of CASTOR
Andrew G Spencer et al. · Haematologica
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20 Sep 2018 |
262 |
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Endovascular treatment versus no endovascular treatment after 6–24 h in patients with ischaemic stroke and collateral flow on CT angiography (MR CLEAN-LATE) in the Netherlands: a multicentre, open-label, blinded-endpoint, randomised, controlled, phase 3 trial
Susanne G. H. Olthuis et al. · The Lancet
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29 Mar 2023 |
258 |
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Risk of recurrent high-grade cervical intraepithelial neoplasia after successful treatment: a long-term multi-cohort study
Mariëlle Kocken, Theo J.M. Helmerhorst, Johannes Hans Berkhof et al. · The Lancet Oncology
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30 Apr 2011 |
254 |
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Dysbiosis of upper respiratory tract microbiota in elderly pneumonia patients
Wouter A. A. de Steenhuijsen Piters, Elisabeth G. W. Huijskens, Anne L. Wyllie et al. · The ISME Journal
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7 Jul 2015 |
253 |
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Very thin strut biodegradable polymer everolimus-eluting and sirolimus-eluting stents versus durable polymer zotarolimus-eluting stents in allcomers with coronary artery disease (BIO-RESORT): a three-arm, randomised, non-inferiority trial
Clemens von Birgelen, Marlies M. Kok, Liefke C. van der Heijden et al. · The Lancet
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30 Oct 2016 |
251 |
| 23 |
Remote haemodynamic monitoring of pulmonary artery pressures in patients with chronic heart failure (MONITOR-HF): a randomised clinical trial
Jasper Jan Brugts et al. · The Lancet
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20 May 2023 |
248 |
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European Guideline on IgG4‐related digestive disease – UEG and SGF evidence‐based recommendations
Matthias J. Löhr et al. · United European Gastroenterology Journal
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18 Jun 2020 |
248 |
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A comparison of hemiarthroplasty with total hip replacement for displaced intracapsular fracture of the femoral neck
Michel P.J. van den Bekerom, E. F. Hilverdink, Inger Nicoline Sierevelt et al. · Journal of Bone and Joint Surgery - British Volume
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30 Sep 2010 |
248 |
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Idiopathic Retroperitoneal Fibrosis
Eric F.H. van Bommel, Inger Jansen, Tadek R. Hendriksz et al. · Medicine
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243 |
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Fixed-Duration Ibrutinib-Venetoclax in Patients with Chronic Lymphocytic Leukemia and Comorbidities
Arnon Philip Kater et al. · NEJM Evidence
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13 May 2022 |
240 |
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Vertebroplasty versus sham procedure for painful acute osteoporotic vertebral compression fractures (VERTOS IV): randomised sham controlled clinical trial
Cristina E. Firanescu, Jolanda De Vries, Paul Lodder et al. · BMJ
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9 May 2018 |
239 |
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The Prevalence and Prognostic Value of Low Muscle Mass in Cancer Patients: A Review of the Literature
Hánah N. Rier, Agnes Jager, Stefan Sleijfer et al. · The Oncologist
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13 Jul 2016 |
228 |
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Ecological Effects of Selective Decontamination on Resistant Gram-negative Bacterial Colonization
Evelien A. N. Oostdijk, Anne Marie G. A. de Smet, Hetty E. M. Blok et al. · American Journal of Respiratory and Critical Care Medicine
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3 Dec 2009 |
226 |
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Hypertrophic cardiomyopathy in a large community-based population: clinical outcome and identification of risk factors for sudden cardiac death and clinical deterioration
Marcel J.M. Kofflard, Folkert J. ten Cate, Chris van der Lee et al. · Journal of the American College of Cardiology
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Mar 2003 |
220 |
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Hartmann's procedure versus sigmoidectomy with primary anastomosis for perforated diverticulitis with purulent or faecal peritonitis (LADIES): a multicentre, parallel-group, randomised, open-label, superiority trial
Daniël P. V. Lambrichts et al. · The Lancet. Gastroenterology & hepatology
Open access178 authors |
7 Jun 2019 |
216 |
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A randomized controlled, non-inferiority trial of modified natural versus artificial cycle for cryo-thawed embryo transfer
Eva R. Groenewoud et al. · Human Reproduction
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13 May 2016 |
216 |
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Concentrations of Blood Components in Commercial Platelet-Rich Plasma Separation Systems: A Review of the Literature
Bart W. Oudelaar, Joost C. Peerbooms, Rianne Huis in ‘t Veld et al. · The American Journal of Sports Medicine
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16 Jan 2018 |
212 |
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Successful Transfer of Umbilical Cord Blood CD34+ Hematopoietic Stem and Progenitor-derived NK Cells in Older Acute Myeloid Leukemia Patients
Harry Dolstra et al. · Clinical Cancer Research
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9 Mar 2017 |
212 |
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Comparison of eight prehospital stroke scales to detect intracranial large-vessel occlusion in suspected stroke (PRESTO): a prospective observational study
Martijne H.C. Duvekot et al. · The Lancet Neurology
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9 Jan 2021 |
210 |
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Induction of Labor versus Expectant Management in Women with Preterm Prelabor Rupture of Membranes between 34 and 37 Weeks: A Randomized Controlled Trial
David P. van der Ham et al. · PLoS Medicine
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24 Apr 2012 |
207 |
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Optimal Duration of Extended Adjuvant Endocrine Therapy for Early Breast Cancer; Results of the IDEAL Trial (BOOG 2006-05)
Erik J. Blok, Judith R. Kroep, Elma Meershoek‐Klein Kranenbarg et al. · JNCI Journal of the National Cancer Institute
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30 May 2017 |
203 |
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Condom use promotes regression of cervical intraepithelial neoplasia and clearance of human papillomavirus: A randomized clinical trial
Cornelis J.A. Hogewoning, Maaike C.G. Bleeker, Adriaan J. C. van den Brule et al. · International Journal of Cancer
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12 Sep 2003 |
203 |
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Fosfomycin: Pharmacological, Clinical and Future Perspectives
Anneke C. Dijkmans, Natalia V. Ortiz Zacarı́as, Jacobus Burggraaf et al. · Antibiotics
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31 Oct 2017 |
200 |
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Management of late-preterm premature rupture of membranes: the PPROMEXIL-2 trial
David P. van der Ham, Jantien L. van der Heyden, Brent C. Opmeer et al. · American Journal of Obstetrics and Gynecology
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20 Jul 2012 |
200 |
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Mesh versus suture repair of umbilical hernia in adults: a randomised, double-blind, controlled, multicentre trial
Ruth Kaufmann, Jens Anthony Halm, Hasan Huseyin Eker et al. · The Lancet
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17 Feb 2018 |
195 |
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Digital morphology analyzers in hematology: ICSH review and recommendations
Alexander F. Kratz, Szu‐Hee Lee, Gina Zini et al. · International Journal of Laboratory Hematology
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2 May 2019 |
192 |
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Chronic lymphocytic leukemia cells impair mitochondrial fitness in CD8+ T cells and impede CAR T-cell efficacy
Jaco A. C. van Bruggen, Anne W. J. Martens, Joseph A. Fraietta et al. · Blood
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10 May 2019 |
192 |
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Ten‐year recurrence rates for breast cancer subtypes in the Netherlands: A large population‐based study
Marissa Corine van Maaren, Linda de Munck, Luc J. A. Strobbe et al. · International Journal of Cancer
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28 Oct 2018 |
189 |
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Selective digestive tract decontamination and selective oropharyngeal decontamination and antibiotic resistance in patients in intensive-care units: an open-label, clustered group-randomised, crossover study
Anne Marie G. A. de Smet, Jan A. J. W. Kluytmans, Hetty E. M. Blok et al. · The Lancet Infectious Diseases
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30 Apr 2011 |
187 |
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Maintenance with daratumumab or observation following treatment with bortezomib, thalidomide, and dexamethasone with or without daratumumab and autologous stem-cell transplant in patients with newly diagnosed multiple myeloma (CASSIOPEIA): an open-label, randomised, phase 3 trial
Philippe Moreau et al. · The Lancet Oncology
Open access |
13 Sep 2021 |
180 |
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Morbidly Obese Human Subjects Have Increased Peripheral Blood CD4+ T Cells With Skewing Toward a Treg- and Th2-Dominated Phenotype
Kim van der Weerd, Willem A. Dik, Benjamin Schrijver et al. · Diabetes
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7 Jan 2012 |
179 |
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Randomized clinical trial of non-mesh versus mesh repair of primary inguinal hernia
W. W. Vrijland, M. Petrousjka van den Tol, Roland W. Luijendijk et al. · British journal of surgery
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177 |
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Stimulation of osteogenic differentiation in human osteoprogenitor cells by pulsed electromagnetic fields: an in vitro study
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23 Aug 2010 |
176 |