Institution · Alexander Fleming Biomedical Sciences Research Center
Most cited papers from Alexander Fleming Biomedical Sciences Research Center
What are the most cited papers from Alexander Fleming Biomedical Sciences Research Center?
The most cited paper from Alexander Fleming Biomedical Sciences Research Center is "Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes" (Andrew Paul Morris et al., 2012), with 2,021 citations. Next come "Onset and Progression in Inherited ALS Determined by Motor Neurons and Microglia" (1,629) and "DIANA-microT web server v5.0: service integration into miRNA functional analysis workflows" (1,209).
Showing 50 of 60 papers. Every paper with more than 251 citations is listed.
| # | Paper | ||
|---|---|---|---|
| 1 | Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes Andrew Paul Morris et al. · Nature Genetics | 12 Aug 2012 | 2,021 |
| 2 | Onset and Progression in Inherited ALS Determined by Motor Neurons and Microglia Séverine Boillée, Koji Yamanaka, Christian S. Lobsiger et al. · Science | Jun 2006 | 1,629 |
| 3 | DIANA-microT web server v5.0: service integration into miRNA functional analysis workflows Maria D. Paraskevopoulou, Georgios K. Georgakilas, Nikos Kostoulas et al. · Nucleic Acids Research | 16 May 2013 | 1,209 |
| 4 | Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility Anubha Mahajan et al. · Nature Genetics | 9 Feb 2014 | 1,085 |
| 5 | CXCR4-activated astrocyte glutamate release via TNFα: amplification by microglia triggers neurotoxicity Paola Bezzi, Marı́a Domercq, Liliana Brambilla et al. · Nature Neuroscience | Jul 2001 | 1,080 |
| 6 | Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition) Andrea Cossarizza et al. · European Journal of Immunology | Oct 2019 | 1,014 |
| 7 | CYLD is a deubiquitinating enzyme that negatively regulates NF-κB activation by TNFR family members Eirini Trompouki, Eudoxia Hatzivassiliou, Theodore Tsichritzis et al. · Nature | Aug 2003 | 972 |
| 8 | Human C-reactive protein: expression, structure, and function John E. Volanakis · Molecular Immunology | Aug 2001 | 936 |
| 9 | Five-Vertebrate ChIP-seq Reveals the Evolutionary Dynamics of Transcription Factor Binding Dominic Schmidt, Michael D. Wilson, Benoît Ballester et al. · Science | 8 Apr 2010 | 746 |
| 10 | Deciphering the Transcriptional Histone Acetylation Code for a Human Gene Theodora Agalioti, Guoying Chen, Dimitris Thanos · Cell | Nov 2002 | 638 |
| 11 | Fibroblasts as immune regulators in infection, inflammation and cancer Sarah Davidson, Mark Christopher Coles, Tom R Thomas et al. · Nature reviews. Immunology | 28 Apr 2021 | 627 |
| 12 | DIANA-microT web server: elucidating microRNA functions through target prediction Manolis Maragkakis, Martin Reczko, Victor A. Simossis et al. · Nucleic Acids Research | 30 Apr 2009 | 573 |
| 13 | DIANA miRPath v.2.0: investigating the combinatorial effect of microRNAs in pathways Ioannis S. Vlachos, Nikos Kostoulas, Thanasis Vergoulis et al. · Nucleic Acids Research | 30 May 2012 | 537 |
| 14 | Genomic and epigenetic alterations deregulate microRNA expression in human epithelial ovarian cancer Lin Zhang et al. · Proceedings of the National Academy of Sciences | 5 May 2008 | 524 |
| 15 | A role for Dicer in immune regulation Bradley S. Cobb, Arnulf Hertweck, James C. Smith et al. · The Journal of Experimental Medicine | 23 Oct 2006 | 523 |
| 16 | Osteoclasts are essential for TNF-α–mediated joint destruction Kurt Redlich, Silvia Hayer, Roméo Ricci et al. · Journal of Clinical Investigation | 15 Nov 2002 | 474 |
| 17 | Sex-stratified Genome-wide Association Studies Including 270,000 Individuals Show Sexual Dimorphism in Genetic Loci for Anthropometric Traits Joshua C. Randall et al. · PLoS Genetics | 6 Jun 2013 | 462 |
| 18 | Proof of concept: enthesitis and new bone formation in spondyloarthritis are driven by mechanical strain and stromal cells Peggy Jacques, Stijn Lambrecht, Eveline Verheugen et al. · Annals of the Rheumatic Diseases | 7 Aug 2013 | 437 |
| 19 | Interaction of Akt-Phosphorylated Ataxin-1 with 14-3-3 Mediates Neurodegeneration in Spinocerebellar Ataxia Type 1 Hung-Kai Chen, Pedro Fernández-Fúnez, Summer F. Acevedo et al. · Cell | May 2003 | 417 |
| 20 | The database of experimentally supported targets: a functional update of TarBase Giorgio Lucio Papadopoulos, Martin Reczko, Victor A. Simossis et al. · Nucleic Acids Research | 29 Oct 2008 | 409 |
| 21 | Three DNA Polymerases, Recruited by Different Mechanisms, Carry Out NER Repair Synthesis in Human Cells Tomoo Ogi, Siripan Limsirichaikul, René Overmeer et al. · Molecular Cell | Mar 2010 | 395 |
| 22 | Endothelial Cell-Specific NF-κB Inhibition Protects Mice from Atherosclerosis Ralph Gareus, Elena Kotsaki, Sofia Xanthoulea et al. · Cell Metabolism | Nov 2008 | 388 |
| 23 | Impact of Type 2 Diabetes Susceptibility Variants on Quantitative Glycemic Traits Reveals Mechanistic Heterogeneity Antigone S. Dimas et al. · Diabetes | 3 Dec 2013 | 385 |
| 24 | Thyroid hormone inhibits lung fibrosis in mice by improving epithelial mitochondrial function Guoying Yu et al. · Nature Medicine | 4 Dec 2017 | 374 |
| 25 | Mesenchymal cell targeting by TNF as a common pathogenic principle in chronic inflammatory joint and intestinal diseases Maria Armaka, Maria D. Apostolaki, Peggy Jacques et al. · The Journal of Experimental Medicine | 4 Feb 2008 | 374 |
| 26 | Genetic evidence of assortative mating in humans Matthew R. Robinson et al. · Nature Human Behaviour | 9 Jan 2017 | 371 |
| 27 | Advances in De Novo Drug Design: From Conventional to Machine Learning Methods Varnavas D. Mouchlis, Antreas Afantitis, Angela Serra et al. · International Journal of Molecular Sciences | 7 Feb 2021 | 364 |
| 28 | Blockade of TNF-α rapidly inhibits pain responses in the central nervous system Andreas Heß, Roland Axmann, Jürgen Rech et al. · Proceedings of the National Academy of Sciences | 18 Jan 2011 | 360 |
| 29 | Lysine Methylation Regulates E2F1-Induced Cell Death Haroula Kontaki, Iannis Talianidis · Molecular Cell | Jul 2010 | 359 |
| 30 | DIANA-LncBase: experimentally verified and computationally predicted microRNA targets on long non-coding RNAs Maria D. Paraskevopoulou, Georgios K. Georgakilas, Nikos Kostoulas et al. · Nucleic Acids Research | 27 Nov 2012 | 351 |
| 31 | Neuroinflammatory TNFα Impairs Memory via Astrocyte Signaling Samia Habbas, Mirko Santello, Denise Becker et al. · Cell | Dec 2015 | 349 |
| 32 | STAT3 activation through IL-6/IL-11 in cancer-associated fibroblasts promotes colorectal tumour development and correlates with poor prognosis Christina Heichler et al. · Gut | 4 Nov 2019 | 339 |
| 33 | Accurate microRNA target prediction correlates with protein repression levels Manolis Maragkakis, Panagiotis Alexiou, Giorgio Lucio Papadopoulos et al. · BMC Bioinformatics | 18 Sep 2009 | 339 |
| 34 | Uncoupling the Proinflammatory from the Immunosuppressive Properties of Tumor Necrosis Factor (Tnf) at the P55 TNF Receptor Level George Kassiotis, George Kollias · The Journal of Experimental Medicine | 12 Feb 2001 | 337 |
| 35 | The tumor-promoting actions of TNF-α involve TNFR1 and IL-17 in ovarian cancer in mice and humans Kellie A. Charles, Hagen Kulbe, Robin Soper et al. · Journal of Clinical Investigation | 9 Sep 2009 | 337 |
| 36 | Frequency and fate of microRNA editing in human brain Yukio Kawahara, Molly S. Megraw, Edward F. Kreider et al. · Nucleic Acids Research | 6 Aug 2008 | 334 |
| 37 | Exploring Animal Models That Resemble Idiopathic Pulmonary Fibrosis Jun Tashiro, Gustavo A. Rubio, Andrew H. Limper et al. · Frontiers in Medicine | 28 Jul 2017 | 331 |
| 38 | Lost in translation: an assessment and perspective for computational microRNA target identification Panagiotis Alexiou, Manolis Maragkakis, Giorgio Lucio Papadopoulos et al. · Computer applications in the biosciences | 29 Sep 2009 | 327 |
| 39 | MAP kinase phosphatases. Aspasia Theodosiou, Alan Ashworth · Genome biology | 2002 | 327 |
| 40 | Characterization of Flavonoid Subgroups and Hydroxy Substitution by HPLC-MS/MS Dimitrios Tsimogiannis, Martina K. Samiotaki, George Panayotou et al. · Molecules | 21 Mar 2007 | 324 |
| 41 | Tumor hypoxia induces nuclear paraspeckle formation through HIF-2α dependent transcriptional activation of NEAT1 leading to cancer cell survival Hani Choudhry, Ashwag Albukhari, Matteo Morotti et al. · Oncogene | 24 Nov 2014 | 318 |
| 42 | Modeling pulmonary fibrosis with bleomycin Marios Angelos Mouratis, Vassilis Aidinis · Current Opinion in Pulmonary Medicine | Sep 2011 | 317 |
| 43 | RANKL inhibition improves muscle strength and insulin sensitivity and restores bone mass Nicolas Bonnet, Lucie Bourgoin, Emmanuel Biver et al. · Journal of Clinical Investigation | 23 May 2019 | 315 |
| 44 | Paracrine orchestration of intestinal tumorigenesis by a mesenchymal niche Manolis Roulis et al. · Nature | Apr 2020 | 312 |
| 45 | Single and combined inhibition of tumor necrosis factor, interleukin‐1, and RANKL pathways in tumor necrosis factor–induced arthritis: Effects on synovial inflammation, bone erosion, and cartilage destruction Jochen Zwerina, Silvia Hayer, Makiyeh Tohidast-Akrad et al. · Arthritis & Rheumatism | 2004 | 310 |
| 46 | Inducible Transgenic Mice Reveal Resting Dendritic Cells as Potent Inducers of CD8+ T Cell Tolerance Hans Christian Probst, Jacques Lagnel, George Kollias et al. · Immunity | May 2003 | 306 |
| 47 | Symbionts Commonly Provide Broad Spectrum Resistance to Viruses in Insects: A Comparative Analysis of Wolbachia Strains Julien Martinez, Ben Longdon, Simone Bauer et al. · PLoS Pathogens | 18 Sep 2014 | 305 |
| 48 | A Guide to Conquer the Biological Network Era Using Graph Theory Mikaela Koutrouli, Evangelos Karatzas, David Páez-Espino et al. · Frontiers in Bioengineering and Biotechnology | 30 Jan 2020 | 287 |
| 49 | UV-sensitive syndrome protein UVSSA recruits USP7 to regulate transcription-coupled repair Petra Schwertman, Anna Lagarou, Dick H. W. Dekkers et al. · Nature Genetics | Apr 2012 | 281 |
| 50 | Ascl2 Acts as an R-spondin/Wnt-Responsive Switch to Control Stemness in Intestinal Crypts Jurian Schuijers, Jan Philipp Junker, Michal Mokrý et al. · Cell stem cell | 22 Jan 2015 | 280 |
Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.