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Most cited papers from Altimmune (United States)

What are the most cited papers from Altimmune (United States)?

The most cited paper from Altimmune (United States) is "New use of BCG for recombinant vaccines" (C. Kendall Stover, Vidal F. de la Cruz, Thomas R. Fuerst et al., 1991), with 1,513 citations. Next come "Targeting interleukin-6 in inflammatory autoimmune diseases and cancers" (674) and "Development of a Humanized Monoclonal Antibody (MEDI‐493) with Potent In Vitro and In Vivo Activity against Respiratory Syncytial Virus" (647).

Showing 50 of 61 papers. Every paper with more than 99 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 New use of BCG for recombinant vaccines C. Kendall Stover, Vidal F. de la Cruz, Thomas R. Fuerst et al. · Nature 6 Jun 1991 1,513
2 Targeting interleukin-6 in inflammatory autoimmune diseases and cancers Xin Yao, Jiaqi Huang, Haihong Zhong et al. · Pharmacology & Therapeutics 27 Sep 2013 674
3 Development of a Humanized Monoclonal Antibody (MEDI‐493) with Potent In Vitro and In Vivo Activity against Respiratory Syncytial Virus Syd Johnson, Cynthia N. Oliver, Gregory A. Prince et al. · The Journal of Infectious Diseases Open access Nov 1997 647
4 Host expression of PD-L1 determines efficacy of PD-L1 pathway blockade–mediated tumor regression Heng Lin, Shuang Wei, Elaine M. Hurt et al. · Journal of Clinical Investigation Open access 15 Jan 2018 610
5 CD38-Mediated Immunosuppression as a Mechanism of Tumor Cell Escape from PD-1/PD-L1 Blockade Limo Chen et al. · Cancer Discovery Open access 16 Jul 2018 481
6 Rational Selection of Syngeneic Preclinical Tumor Models for Immunotherapeutic Drug Discovery Suzanne I.S. Mosely et al. · Cancer Immunology Research 6 Dec 2016 439
7 Recent trends in severe respiratory syncytial virus (RSV) among US infants, 1997 to 2000 Shelah Leader, Kimmie F. Kohlhase · The Journal of Pediatrics Nov 2003 431
8 Severe Human Lower Respiratory Tract Illness Caused by Respiratory Syncytial Virus and Influenza Virus Is Characterized by the Absence of Pulmonary Cytotoxic Lymphocyte Responses Timothy P. Welliver, Roberto P. Garofalo, Yashoda Madaiah Hosakote et al. · The Journal of Infectious Diseases Open access 15 Mar 2007 426
9 Identification and Characterization of MEDI4736, an Antagonistic Anti–PD-L1 Monoclonal Antibody Ross A. Stewart et al. · Cancer Immunology Research 6 May 2015 416
10 The Immunoscore: Colon Cancer and Beyond Helen K. Angell, Daniela Bruni, J. Carl Barrett et al. · Clinical Cancer Research 14 Aug 2019 411
11 Transfer of HIV-1-specific cytotoxic T lymphocytes to an AIDS patient leads to selection for mutant HIV variants and subsequent disease progression Scott Koenig, Anthony J. Conley, Yambasu A. Brewah et al. · Nature Medicine Apr 1995 382
12 A highly potent extended half-life antibody as a potential RSV vaccine surrogate for all infants Qing Zhu, Jason S. McLellan, Nicole L. Kallewaard et al. · Science Translational Medicine 3 May 2017 374
13 TP53, STK11 , and EGFR Mutations Predict Tumor Immune Profile and the Response to Anti–PD-1 in Lung Adenocarcinoma Jérôme Biton, Audrey Mansuet‐Lupo, Nicolas Pécuchet et al. · Clinical Cancer Research 15 May 2018 372
14 Biosynthesis and processing of endogenous BDNF: CNS neurons store and secrete BDNF, not pro-BDNF Tomoya Matsumoto, Stefanie Rauskolb, Martin Polack et al. · Nature Neuroscience 20 Jan 2008 362
15 Type I interferon–inducible gene expression in blood is present and reflects disease activity in dermatomyositis and polymyositis Ronan J. Walsh, Sek Won Kong, Yihong Yao et al. · Arthritis & Rheumatism Open access 29 Oct 2007 308
16 Targeting CD73 in the tumor microenvironment with MEDI9447 Carl M. Hay, Erin Sult, Qihui Huang et al. · OncoImmunology Open access 11 Jul 2016 292
17 Interleukin-6 Stimulates Defective Angiogenesis Ganga Gopinathan, Carla S. Milagre, Oliver M.T. Pearce et al. · Cancer Research Open access 16 Jun 2015 255
18 Hypoxia‐induced production of stromal cell–derived factor 1 (CXCL12) and vascular endothelial growth factor by synovial fibroblasts Carol Ann Hitchon, Keng Wong, Guoping Ma et al. · Arthritis & Rheumatism Oct 2002 253
19 Robust anti‐obesity and metabolic effects of a dual GLP ‐1/glucagon receptor peptide agonist in rodents and non‐human primates Susan J Henderson et al. · Diabetes Obesity and Metabolism Open access 5 Jul 2016 239
20 Predictive value of the EphA2 receptor tyrosine kinase in lung cancer recurrence and survival. Michael S. Kinch, Mary-Beth H Moore, David H. Harpole · PubMed Feb 2003 239
21 Persistence of Morbidity and Cost Differences Between Late-Preterm and Term Infants During the First Year of Life Kimmie K. McLaurin, Caroline Breese Hall, Elizabeth Anne Jackson et al. · PEDIATRICS 26 Jan 2009 234
22 Molecular and clinical rationale for therapeutic targeting of interleukin‐5 and its receptor Néstor A. Molfino, David L. Gossage, R. Kolbeck et al. · Clinical & Experimental Allergy 23 Sep 2011 216
23 A randomized trial of benralizumab, an antiinterleukin 5 receptor α monoclonal antibody, after acute asthma Richard M. Nowak, Joseph M. Parker, Robert A. Silverman et al. · The American Journal of Emergency Medicine 5 Oct 2014 208
24 Self-reactive IgE exacerbates interferon responses associated with autoimmunity Jill Hénault, Jeffrey M. Riggs, Jodi L. Karnell et al. · Nature Immunology Open access 21 Dec 2015 188
25 Adhesins as Targets for Vaccine Development Theresa M. Wizemann, John E. Adamou, Solomon Langermann · Emerging infectious diseases Open access Jun 1999 182
26 A phase 1b clinical trial evaluating sifalimumab, an anti-IFN-α monoclonal antibody, shows target neutralisation of a type I IFN signature in blood of dermatomyositis and polymyositis patients Brandon W. Higgs, Wei Zhu, Chris Morehouse et al. · Annals of the Rheumatic Diseases Open access 24 Feb 2013 170
27 Identification of a Single Tryptophan Residue as Critical for Binding Activity in a Humanized Monoclonal Antibody against Respiratory Syncytial Virus Ziping Wei, Jinhua Feng, Hung‐Yu Lin et al. · Analytical Chemistry 24 Feb 2007 170
28 Respiratory Syncytial Virus (RSV) Immune Globulin Intravenous Therapy for RSV Lower Respiratory Tract Infection in Infants and Young Children at High Risk for Severe RSV Infections William J. Rodriguez, William C. Gruber, Charles Welliver et al. · PEDIATRICS Mar 1997 170
29 IL ‐33 drives airway hyper‐responsiveness through IL ‐13‐mediated mast cell: airway smooth muscle crosstalk Davinder Kaur, E. Gomez, Camille Doe et al. · Allergy Open access 13 Feb 2015 167
30 Systemic and mucosal immunity induced by BCG vector expressing outer-surface protein A of Borrelia burgdorferi Solomon Langermann, Susan Palaszynski, A Sădziene et al. · Nature Open access 8 Dec 1994 167
31 Effect of pemvidutide, a GLP-1/glucagon dual receptor agonist, on MASLD: A randomized, double-blind, placebo-controlled study Stephen A. Harrison, Sarah Browne, John J. Suschak et al. · Journal of Hepatology Open access 11 Jul 2024 166
32 Concurrent PD-1 Blockade Negates the Effects of OX40 Agonist Antibody in Combination Immunotherapy through Inducing T-cell Apoptosis Rajeev Kumar Shrimali, Shamim Ahmad, Vivek Verma et al. · Cancer Immunology Research 28 Aug 2017 160
33 Idiopathic Pulmonary Fibrosis in United States Automated Claims: Incidence, Prevalence, and Algorithm Validation Daina B. Esposito, Stephan Lanes, Macarius M. Donneyong et al. · American Journal of Respiratory and Critical Care Medicine 4 Aug 2015 157
34 Improving target cell specificity using a novel monovalent bispecific IgG design Yariv Mazor, Vaheh Oganesyan, Chunning Yang et al. · mAbs Open access 26 Jan 2015 154
35 A First-Time-in-Human Study of GSK2636771, a Phosphoinositide 3 Kinase Beta-Selective Inhibitor, in Patients with Advanced Solid Tumors Joaquı́n Mateo et al. · Clinical Cancer Research Open access 23 Jun 2017 149
36 Immunotherapy Targeting HPV16/18 Generates Potent Immune Responses in HPV-Associated Head and Neck Cancer Charu Aggarwal et al. · Clinical Cancer Research Open access 21 Sep 2018 147
37 MiR-125a targets effector programs to stabilize Treg-mediated immune homeostasis Wen Qi Pan et al. · Nature Communications Open access 12 May 2015 147
38 Genetically Encoded Azide Containing Amino Acid in Mammalian Cells Enables Site-Specific Antibody–Drug Conjugates Using Click Cycloaddition Chemistry Michael Pete VanBrunt, Kurt D. Shanebeck, Zachary Caldwell et al. · Bioconjugate Chemistry 2 Sep 2015 144
39 Overexpression and functional alterations of the EphA2 tyrosine kinase in cancer Michael S. Kinch, Kelly Carles‐Kinch · Clinical & Experimental Metastasis Feb 2003 137
40 Activation of the EphA2 tyrosine kinase stimulates the MAP/ERK kinase signaling cascade Rebecca L. Pratt, Michael S. Kinch · Oncogene 25 Oct 2002 136
41 Synovial fibroblasts self‐direct multicellular lining architecture and synthetic function in three‐dimensional organ culture Hans Peter Kiener, Gerald F. Watts, Yajun Cui et al. · Arthritis & Rheumatism 7 Jan 2010 135
42 Neuromyelitis optica spectrum disorder Janine B. Beekman, Aysha Keisler, Omar Pedraza et al. · Neurology Neuroimmunology & Neuroinflammation Open access 21 Jun 2019 134
43 Angiopoietin 2 regulates the transformation and integrity of lymphatic endothelial cell junctions Wei Zheng, Harri J. Nurmi, Sila Appak‐Baskoy et al. · Genes & Development Open access 15 Jul 2014 134
44 Single-Dose Intranasal Administration of AdCOVID Elicits Systemic and Mucosal Immunity against SARS-CoV-2 and Fully Protects Mice from Lethal Challenge Rodney Glenn King et al. · Vaccines Open access 9 Aug 2021 125
45 Role of B Cell–Activating Factor in Chronic Obstructive Pulmonary Disease Leen Seys, Anne Verhamme, Anja Schinwald et al. · American Journal of Respiratory and Critical Care Medicine 12 Aug 2015 124
46 Burden of paediatric influenza in Western Europe: a systematic review Evgeniya N. Antonova, Catherine E. Rycroft, Christopher S. Ambrose et al. · BMC Public Health ReviewOpen access 12 Nov 2012 119
47 Role of CXCL13 in Cigarette Smoke–induced Lymphoid Follicle Formation and Chronic Obstructive Pulmonary Disease Ken R. Bracke, Anne Verhamme, Leen Seys et al. · American Journal of Respiratory and Critical Care Medicine 6 Jun 2013 117
48 A high density of tertiary lymphoid structure B cells in lung tumors is associated with increased CD4+T cell receptor repertoire clonality Wei Zhu, Claire Germain, Zheng Liu et al. · OncoImmunology Open access Jun 2015 116
49 Inhibition of CD73 AMP hydrolysis by a therapeutic antibody with a dual, non-competitive mechanism of action James C. Geoghegan, Gundo Diedrich, Xiaojun Lu et al. · mAbs Open access 8 Feb 2016 114
50 B-cell targeted therapeutics in clinical development Stephan Blüml, Kathleen McKeever, Rachel Ettinger et al. · Arthritis Research & Therapy Open access Mar 2013 110

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.