| 1 |
Bremelanotide for the Treatment of Hypoactive Sexual Desire Disorder
Sheryl A. Kingsberg, Anita H. Clayton, David Jay Portman et al. · Obstetrics and Gynecology
Open access |
10 Oct 2019 |
296 |
| 2 |
Ferumoxytol for Treating Iron Deficiency Anemia in CKD
Bruce Spinowitz, Annamaria T. Kausz, Jovanna Baptista et al. · Journal of the American Society of Nephrology
Open access |
4 Jun 2008 |
260 |
| 3 |
17-OHPC to Prevent Recurrent Preterm Birth in Singleton Gestations (PROLONG Study): A Multicenter, International, Randomized Double-Blind Trial
Sean C. Blackwell et al. · American Journal of Perinatology
Open access |
25 Oct 2019 |
236 |
| 4 |
Female Sexual Health: Barriers to Optimal Outcomes and a Roadmap for Improved Patient–Clinician Communications
Sheryl A. Kingsberg, Jonathan Schaffir, Brooke M. Faught et al. · Journal of Women s Health
Open access |
4 Feb 2019 |
224 |
| 5 |
Microneedle-based device for the one-step painless collection of capillary blood samples
Timothy M. Blicharz, Ping Gong, Bernard M Bunner et al. · Nature Biomedical Engineering
|
16 Feb 2018 |
224 |
| 6 |
Long-Term Safety and Efficacy of Bremelanotide for Hypoactive Sexual Desire Disorder
James A. Simon, Sheryl A. Kingsberg, David Jay Portman et al. · Obstetrics and Gynecology
Open access |
10 Oct 2019 |
198 |
| 7 |
Randomized trial of intravenous iron-induced hypophosphatemia
Myles Selig Wolf, Glenn Matthew Chertow, Iain C. Macdougall et al. · JCI Insight
Open access |
5 Dec 2018 |
196 |
| 8 |
Physicochemical properties of ferumoxytol, a new intravenous iron preparation
V.S. Balakrishnan, Madhumathi Rao, Annamaria T. Kausz et al. · European Journal of Clinical Investigation
|
23 Apr 2009 |
145 |
| 9 |
Safety of Ferumoxytol in Patients With Anemia and CKD
Ajay Singh, Tejas V. Patel, Joachim Hertel et al. · American Journal of Kidney Diseases
|
29 Sep 2008 |
145 |
| 10 |
Comparative safety of intravenous ferumoxytol versus ferric carboxymaltose in iron deficiency anemia: A randomized trial
N. Franklin Adkinson, William Strauss, Iain C. Macdougall et al. · American Journal of Hematology
Open access |
8 Feb 2018 |
129 |
| 11 |
Encoded Library Synthesis Using Chemical Ligation and the Discovery of sEH Inhibitors from a 334-Million Member Library
Alexander Litovchick, Christoph E. Dumelin, Sevan Habeshian et al. · Scientific Reports
Open access |
10 Jun 2015 |
104 |
| 12 |
A Randomized Comparison of Ferumoxytol and Iron Sucrose for Treating Iron Deficiency Anemia in Patients with CKD
Iain C. Macdougall, William Strauss, Justin McLaughlin et al. · Clinical Journal of the American Society of Nephrology
Open access |
23 Jan 2014 |
101 |
| 13 |
Qualitative and quantitative validation of the FACIT-fatigue scale in iron deficiency anemia
Sarah Acaster, Rene Dickerhoof, Kendra P.A. DeBusk et al. · Health and Quality of Life Outcomes
Open access |
16 May 2015 |
98 |
| 14 |
Isoform-Selective ATAD2 Chemical Probe with Novel Chemical Structure and Unusual Mode of Action
Amaury E. Fernández‐Montalván et al. · ACS Chemical Biology
Open access |
18 Oct 2017 |
90 |
| 15 |
Hypophosphatemia Associated with Intravenous Iron Therapies for Iron Deficiency Anemia: A Systematic Literature Review
John A. Glaspy, Michelle Z. Lim-Watson, Michael Libre et al. · Therapeutics and Clinical Risk Management
ReviewOpen access |
Apr 2020 |
86 |
| 16 |
Discovery of a Potent BTK Inhibitor with a Novel Binding Mode by Using Parallel Selections with a DNA‐Encoded Chemical Library
John W. Cuozzo, Diana Gikunju, Sevan Habeshian et al. · ChemBioChem
Open access |
5 Jan 2017 |
80 |
| 17 |
A Phase III, randomized, open‐label trial of ferumoxytol compared with iron sucrose for the treatment of iron deficiency anemia in patients with a history of unsatisfactory oral iron therapy
David J. Hetzel, William Strauss, Kristine E. Bernard et al. · American Journal of Hematology
Open access |
18 Mar 2014 |
79 |
| 18 |
Efficacy and safety of IV ferumoxytol for adults with iron deficiency anemia previously unresponsive to or unable to tolerate oral iron
Saroj Vadhan‐Raj, William Strauss, David C. Ford et al. · American Journal of Hematology
Open access |
26 Aug 2013 |
77 |
| 19 |
Evaluation of Dexamethasone Phosphate Delivered by Ocular Iontophoresis for Treating Noninfectious Anterior Uveitis
Amy E. Cohen, Carol Assang, Michael A. Patane et al. · Ophthalmology
|
24 Nov 2011 |
77 |
| 20 |
Safety and efficacy of total dose infusion of 1,020 mg of ferumoxytol administered over 15 min
Michael Auerbach, William Strauss, Sarah A Auerbach et al. · American Journal of Hematology
Open access |
5 Jul 2013 |
76 |
| 21 |
Ciraparantag, an anticoagulant reversal drug: mechanism of action, pharmacokinetics, and reversal of anticoagulants
Jack Ansell, Bryan Laulicht, Sasha Bakhru et al. · Blood
|
18 Nov 2020 |
68 |
| 22 |
Health-related quality of life in patients with iron deficiency anemia: impact of treatment with intravenous iron
William Strauss, Michael Auerbach · Patient Related Outcome Measures
Open access |
Aug 2018 |
64 |
| 23 |
Structure Based Design of Non-Natural Peptidic Macrocyclic Mcl-1 Inhibitors
Jeffrey W. Johannes et al. · ACS Medicinal Chemistry Letters
Open access |
27 Dec 2016 |
61 |
| 24 |
Ophthalmic Drug Delivery Using Iontophoresis: Recent Clinical Applications
Victor L. Perez, Barbara M. Wirostko, Michael S. Korenfeld et al. · Journal of Ocular Pharmacology and Therapeutics
|
22 Nov 2019 |
58 |
| 25 |
Trans-scleral iontophoretic delivery of low molecular weight therapeutics
Sevgi Güngör, Maria Begoña Delgado-Charro, Begoña Ruiz‐Perez et al. · Journal of Controlled Release
Open access |
24 Jul 2010 |
57 |
| 26 |
Discovery of cofactor-specific, bactericidal Mycobacterium tuberculosis InhA inhibitors using DNA-encoded library technology
Holly H. Soutter, Matthew Clark, John W. Cuozzo et al. · Proceedings of the National Academy of Sciences
Open access |
18 Nov 2016 |
55 |
| 27 |
Intravenous Iron-Induced Hypophosphatemia: An Emerging Syndrome
John A. Glaspy, Myles Selig Wolf, William Strauss · Advances in Therapy
Open access |
30 May 2021 |
52 |
| 28 |
Ciraparantag reverses the anticoagulant activity of apixaban and rivaroxaban in healthy elderly subjects
Jack Ansell, Sasha Bakhru, Bryan Laulicht et al. · European Heart Journal
Open access |
8 Sep 2021 |
50 |
| 29 |
Agonists and Antagonists of Protease-Activated Receptor 2 Discovered within a DNA-Encoded Chemical Library Using Mutational Stabilization of the Target
Dean G. Brown et al. · SLAS DISCOVERY
Open access |
12 Jan 2018 |
48 |
| 30 |
KDOQI US Commentary on the KDIGO Clinical Practice Guideline for the Prevention, Diagnosis, Evaluation, and Treatment of Hepatitis C in CKD
Craig E. Gordon, Ethan M. Balk, Bryan N. Becker et al. · American Journal of Kidney Diseases
Open access |
Nov 2008 |
47 |
| 31 |
Aptamer BAX 499 mediates inhibition of tissue factor pathway inhibitor via interaction with multiple domains of the protein
Emily K. Waters, Ryan M. J. Genga, Heather A. Thomson et al. · Journal of Thrombosis and Haemostasis
Open access |
25 Mar 2013 |
45 |
| 32 |
Role of Prohepcidin, Inflammatory Markers and Iron Status in Resistance to rhEPO Therapy in Hemodialysis Patients
Elisio M. Costa, Brian J.G. Pereira, Petronila Rocha‐Pereira et al. · American Journal of Nephrology
|
2008 |
39 |
| 33 |
Reduction of liver fibrosis by rationally designed macromolecular telmisartan prodrugs
Matthew R. Golder et al. · Nature Biomedical Engineering
Open access |
13 Aug 2018 |
37 |
| 34 |
Plasma Pharmacokinetics of Two Consecutive Doses of Ferumoxytol in Healthy Subjects
Amy Barton Pai, Jace C. Nielsen, Annamaria Kausz et al. · Clinical Pharmacology & Therapeutics
|
30 Jun 2010 |
34 |
| 35 |
Ferumoxytol for the treatment of iron deficiency and iron-deficiency anemia of pregnancy
Jesse Gerb, William Strauss, Richard J. Derman et al. · Therapeutic Advances in Hematology
Open access |
2021 |
33 |
| 36 |
Novel Nucleic Acid Binding Small Molecules Discovered Using DNA-Encoded Chemistry
Alexander Litovchick, Tian Xia, Michael I. Monteiro et al. · Molecules
Open access |
27 May 2019 |
33 |
| 37 |
Mode of injection and treatment adherence: results of a survey characterizing the perspectives of health care providers and US women 18–45 years old
David L. Gandell, E. Jay Bienen, Jennifer Gudeman · Patient Preference and Adherence
Open access |
Feb 2019 |
31 |
| 38 |
The neurobiology of bremelanotide for the treatment of hypoactive sexual desire disorder in premenopausal women
James G. Pfaus, Amama Sadiq, Carl Spana et al. · CNS Spectrums
|
18 Jan 2021 |
29 |
| 39 |
Suppression of inflammation and structural damage in experimental arthritis through molecular targeted therapy with PPI‐2458
Gerhard Hannig, Sylvie G. Bernier, Jennifer G. Hoyt et al. · Arthritis & Rheumatism
|
27 Feb 2007 |
29 |
| 40 |
Ferumoxytol versus iron sucrose treatment: a post-hoc analysis of randomized controlled trials in patients with varying renal function and iron deficiency anemia
William Strauss, Naomi V. Dahl, Zhu Li et al. · BMC Hematology
Open access |
26 Jul 2016 |
28 |
| 41 |
Differential responses in CBF and CBV to cocaine as measured by fMRI: Implications for pharmacological MRI signals derived oxygen metabolism assessment
Feng Roger Luo, Karl F. Schmidt, Gerard B. Fox et al. · Journal of Psychiatric Research
|
9 Jan 2009 |
28 |
| 42 |
Evaluation of Ocular and General Safety Following Repeated Dosing of Dexamethasone Phosphate Delivered by Transscleral Iontophoresis in Rabbits
Michael A. Patane, William Schubert, Thomas Richard Sanford et al. · Journal of Ocular Pharmacology and Therapeutics
|
11 Jul 2013 |
28 |
| 43 |
DISC1 regulates N-methyl-D-aspartate receptor dynamics: abnormalities induced by a Disc1 mutation modelling a translocation linked to major mental illness
Elise L.V. Malavasi et al. · Translational Psychiatry
Open access |
6 Sep 2018 |
27 |
| 44 |
Ocular translational science: A review of development steps and paths
Brenda K. Mann, Darren Lars Stirland, Hee‐Kyoung Lee et al. · Advanced Drug Delivery Reviews
Review |
Feb 2018 |
26 |
| 45 |
Requirements for multi-level systems pharmacology models to reach end-usage: the case of type 2 diabetes
Elin Nyman, Yvonne J.W. Wesseling-Rozendaal, Gabriel Helmlinger et al. · Interface Focus
Open access |
19 Feb 2016 |
25 |
| 46 |
Universal strategies for the DNA-encoding of libraries of small molecules using the chemical ligation of oligonucleotide tags
Alexander Litovchick, Matthew Clark, Anthony D. Keefe · Artificial DNA PNA & XNA
Open access |
22 Jan 2014 |
25 |
| 47 |
Chemical ligation methods for the tagging of DNA-encoded chemical libraries
Anthony D. Keefe, Matthew Clark, Christopher D. Hupp et al. · Current Opinion in Chemical Biology
Review |
7 Mar 2015 |
23 |
| 48 |
Ferumoxytol for iron deficiency anemia in patients undergoing hemodialysis. The FACT randomized controlled trial
Iain C. Macdougall, William Strauss, Naomi V. Dahl et al. · Clinical Nephrology
Open access |
25 Feb 2019 |
21 |
| 49 |
Application of a Substrate-Mediated Selection with c-Src Tyrosine Kinase to a DNA-Encoded Chemical Library
Dongwook Kim, Yixing Sun, Dan Xie et al. · Molecules
Open access |
30 Jul 2019 |
19 |
| 50 |
The pharmacokinetics of the lymphotropic nanoparticle MRI contrast agent ferumoxtran-10
Tina Islam, Gerald L Wolf · Cancer Biomarkers
Open access |
2 Mar 2009 |
19 |