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Institution · Amgen (United States)

Most cited papers from Amgen (United States)

What are the most cited papers from Amgen (United States)?

The most cited paper from Amgen (United States) is "2010 Rheumatoid arthritis classification criteria: An American College of Rheumatology/European League Against Rheumatism collaborative initiative" (Daniel Aletaha et al., 2010), with 9,731 citations. Next come "Osteoclast differentiation and activation" (6,707) and "Evolocumab and Clinical Outcomes in Patients with Cardiovascular Disease" (6,185).

Showing 50 of 60 papers. Every paper with more than 1,412 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 2010 Rheumatoid arthritis classification criteria: An American College of Rheumatology/European League Against Rheumatism collaborative initiative Daniel Aletaha et al. · Arthritis & Rheumatism Open access 10 Aug 2010 9,731
2 Osteoclast differentiation and activation William J. Boyle, W. Scott Simonet, David L. Lacey · Nature May 2003 6,707
3 Evolocumab and Clinical Outcomes in Patients with Cardiovascular Disease Marc Steven Sabatine, Robert Patrick Giugliano, ANTHONY C. KEECH et al. · New England Journal of Medicine Open access 17 Mar 2017 6,185
4 Osteoprotegerin Ligand Is a Cytokine that Regulates Osteoclast Differentiation and Activation David L. Lacey et al. · Cell Open access Apr 1998 5,491
5 Detection of Circulating Tumor DNA in Early- and Late-Stage Human Malignancies Chetan Bettegowda et al. · Science Translational Medicine Open access 19 Feb 2014 5,211
6 Osteoprotegerin: A Novel Secreted Protein Involved in the Regulation of Bone Density W. Scott Simonet et al. · Cell Open access Apr 1997 5,161
7 Genetic studies of body mass index yield new insights for obesity biology The LifeLines Cohort Study et al. · Nature Open access487 authors 10 Feb 2015 4,954
8 Molecular characterization of mitochondrial apoptosis-inducing factor Santos A. Susín, Hans Kristian Lorenzo, Naoufal Zamzami et al. · Nature Feb 1999 4,082
9 Effects of the obese Gene Product on Body Weight Regulation in ob / ob Mice Mary Ann Pelleymounter, Mary Jane Cullen, Mary Beth Baker et al. · Science 28 Jul 1995 4,035
10 β-Secretase Cleavage of Alzheimer's Amyloid Precursor Protein by the Transmembrane Aspartic Protease BACE Robert J. Vassar et al. · Science Open access 22 Oct 1999 3,870
11 Biological, clinical and population relevance of 95 loci for blood lipids Tanya M. Teslovich et al. · Nature Open access209 authors Aug 2010 3,706
12 Denosumab for Prevention of Fractures in Postmenopausal Women with Osteoporosis Steven Ron Cummings, Javier San Martín, Michael R. McClung et al. · New England Journal of Medicine Open access 11 Aug 2009 3,503
13 OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesis Young‐Yun Kong, Hiroki Yoshida, Ildiko Sarosi et al. · Nature 1999 3,385
14 The ALSFRS-R: a revised ALS functional rating scale that incorporates assessments of respiratory function Jesse M. Cedarbaum, Nancy Stambler, Errol Malta et al. · Journal of the Neurological Sciences Oct 1999 3,349
15 Wild-Type KRAS Is Required for Panitumumab Efficacy in Patients With Metastatic Colorectal Cancer Rafael G. Amado, Michael Wolf, Marc Peeters et al. · Journal of Clinical Oncology Open access 3 Mar 2008 3,175
16 A Knowledge-Based Approach in Designing Combinatorial or Medicinal Chemistry Libraries for Drug Discovery. 1. A Qualitative and Quantitative Characterization of Known Drug Databases Arup K. Ghose, Vellarkad N. Viswanadhan, John J. Wendoloski · Journal of Combinatorial Chemistry 18 Dec 1998 3,107
17 Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index MAGIC et al. · Nature Genetics Open access376 authors 10 Oct 2010 2,999
18 Raise standards for preclinical cancer research C. Glenn Begley, Lee M. Ellis · Nature Open access 27 Mar 2012 2,968
19 2013 classification criteria for systemic sclerosis: an American college of rheumatology/European league against rheumatism collaborative initiative Frank H J van den Hoogen et al. · Annals of the Rheumatic Diseases 3 Oct 2013 2,941
20 Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition) 1 Daniel J. Klionsky et al. · Autophagy Open access2,930 authors 2 Jan 2021 2,743
21 Mineral Metabolism, Mortality, and Morbidity in Maintenance Hemodialysis Geoffrey A. Block, Preston Klassen, J. Michael Lazarus et al. · Journal of the American Society of Nephrology Aug 2004 2,697
22 Talimogene Laherparepvec Improves Durable Response Rate in Patients With Advanced Melanoma Robert H.I. Andtbacka et al. · Journal of Clinical Oncology 27 May 2015 2,662
23 Functional siRNAs and miRNAs Exhibit Strand Bias Anastasia Khvorova, Angela Reynolds, Sumedha D. Jayasena · Cell Open access Oct 2003 2,649
24 Negative Regulation of PKB/Akt-Dependent Cell Survival by the Tumor Suppressor PTEN Vuk Stambolic, Akira Suzuki, José Luís de la Pompa et al. · Cell Open access Oct 1998 2,587
25 osteoprotegerin-deficient mice develop early onset osteoporosis and arterial calcification Nathan Bucay, Ildiko Sarosi, Colin Robert Dunstan et al. · Genes & Development Open access May 1998 2,498
26 The clinical KRAS(G12C) inhibitor AMG 510 drives anti-tumour immunity Jude R. Canon et al. · Nature 30 Oct 2019 2,329
27 Landscape of Infiltrating T Cells in Liver Cancer Revealed by Single-Cell Sequencing Chunhong Zheng, Liangtao Zheng, Jae‐Kwang Yoo et al. · Cell Open access Jun 2017 2,300
28 Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk Georg Ehret et al. · Nature Open access346 authors 9 Sep 2011 2,085
29 Hundreds of variants clustered in genomic loci and biological pathways affect human height Hana Lango Allen et al. · Nature Open access293 authors 29 Sep 2010 2,063
30 Effects of Recombinant Leptin Therapy in a Child with Congenital Leptin Deficiency I. Sadaf Farooqi, Susan Ann Jebb, Gill Langmack et al. · New England Journal of Medicine Open access 16 Sep 1999 2,022
31 Denosumab versus zoledronic acid for treatment of bone metastases in men with castration-resistant prostate cancer: a randomised, double-blind study Karim S. Fizazi, Michael Anthony Carducci, Matthew R. Smith et al. · The Lancet Open access 26 Feb 2011 1,981
32 Analyzing Learned Molecular Representations for Property Prediction Kevin Yang, Kyle Swanson, Wengong Jin et al. · Journal of Chemical Information and Modeling Open access 30 Jul 2019 1,959
33 The Effects of Normal as Compared with Low Hematocrit Values in Patients with Cardiac Disease Who Are Receiving Hemodialysis and Epoetin Anatole Besarab, Warren Kline Bolton, Jeffrey K. Browne et al. · New England Journal of Medicine Open access 27 Aug 1998 1,947
34 The 2017 international classification of the Ehlers–Danlos syndromes Fransiska Malfait et al. · American Journal of Medical Genetics Part C Seminars in Medical Genetics Open access Mar 2017 1,940
35 Activated T cells regulate bone loss and joint destruction in adjuvant arthritis through osteoprotegerin ligand Young‐Yun Kong et al. · Nature Nov 1999 1,873
36 Sotorasib for Lung Cancers with KRAS p.G12C Mutation Ferdinandos Skoulidis et al. · New England Journal of Medicine Open access 4 Jun 2021 1,862
37 Romosozumab Treatment in Postmenopausal Women with Osteoporosis Felicia Cosman, Daria B. Crittenden, Jonathan Derrick Adachi et al. · New England Journal of Medicine Open access 18 Sep 2016 1,797
38 Angiotensin-converting enzyme 2 is an essential regulator of heart function Michael A. Crackower, Renu Sarao, Gavin Y. Oudit et al. · Nature Jun 2002 1,775
39 The molecular evolution of acquired resistance to targeted EGFR blockade in colorectal cancers Luis Alberto Diaz, Richard Thomas Williams, Jian Wu et al. · Nature Open access Jun 2012 1,760
40 PI3K and cancer: lessons, challenges and opportunities David A. Fruman, Christian Rommel · Nature Reviews Drug Discovery ReviewOpen access 31 Jan 2014 1,760
41 KRAS G12C Inhibition with Sotorasib in Advanced Solid Tumors David S. Hong et al. · New England Journal of Medicine Open access 20 Sep 2020 1,743
42 New genetic loci link adipose and insulin biology to body fat distribution Dmitry Shungin et al. · Nature Open access410 authors 10 Feb 2015 1,726
43 Plasma proteomic associations with genetics and health in the UK Biobank Benjamin B. Sun et al. · Nature Open access 4 Oct 2023 1,716
44 Single-Cell Analyses Inform Mechanisms of Myeloid-Targeted Therapies in Colon Cancer Lei Zhang et al. · Cell Open access Apr 2020 1,715
45 BCL-2, BCL-XL Sequester BH3 Domain-Only Molecules Preventing BAX- and BAK-Mediated Mitochondrial Apoptosis Emily H. Cheng, Michael C. Wei, Solly Weiler et al. · Molecular Cell Open access Sep 2001 1,712
46 Regulation of mouse sterol regulatory element-binding protein-1c gene (SREBP-1c) by oxysterol receptors, LXRα and LXRβ Joyce J. Repa, Guosheng Liang, Jiafu Ou et al. · Genes & Development Open access 15 Nov 2000 1,712
47 Tumor necrosis factor receptor family member RANK mediates osteoclast differentiation and activation induced by osteoprotegerin ligand Hailing Hsu et al. · Proceedings of the National Academy of Sciences Open access 30 Mar 1999 1,648
48 Reflecting on 25 years with MYC Natalie Meyer, Linda Z. Penn · Nature reviews. Cancer Review 24 Nov 2008 1,633
49 Prodrugs: design and clinical applications Jarkko Rautio, Hanna Kumpulainen, Tycho Heimbach et al. · Nature Reviews Drug Discovery Review 25 Jan 2008 1,626
50 Lineage tracking reveals dynamic relationships of T cells in colorectal cancer Lei Zhang, Xin Yu, Liangtao Zheng et al. · Nature 24 Oct 2018 1,624

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.