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Institution · Amyris (United States)

Most cited papers from Amyris (United States)

What are the most cited papers from Amyris (United States)?

The most cited paper from Amyris (United States) is "Production of the antimalarial drug precursor artemisinic acid in engineered yeast" (Dae‐Kyun Ro, Eric M. Paradise, Mario Ouellet et al., 2006), with 2,875 citations. Next come "High-level semi-synthetic production of the potent antimalarial artemisinin" (2,122) and "Rewriting yeast central carbon metabolism for industrial isoprenoid production" (741).

Showing 50 of 60 papers. Every paper with more than 30 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 Production of the antimalarial drug precursor artemisinic acid in engineered yeast Dae‐Kyun Ro, Eric M. Paradise, Mario Ouellet et al. · Nature 13 Apr 2006 2,875
2 High-level semi-synthetic production of the potent antimalarial artemisinin Christopher J. Paddon et al. · Nature Open access Apr 2013 2,122
3 Rewriting yeast central carbon metabolism for industrial isoprenoid production Adam L. Meadows et al. · Nature Sep 2016 741
4 Production of amorphadiene in yeast, and its conversion to dihydroartemisinic acid, precursor to the antimalarial agent artemisinin Patrick J. Westfall, Douglas J. Pitera, Jacob R. Lenihan et al. · Proceedings of the National Academy of Sciences Open access 12 Jan 2012 739
5 Semi-synthetic artemisinin: a model for the use of synthetic biology in pharmaceutical development Christopher J. Paddon, Jay D. Keasling · Nature Reviews Microbiology Review Apr 2014 689
6 High-throughput injection with microfluidics using picoinjectors Adam R. Abate, Tony Hung, Pascaline Mary et al. · Proceedings of the National Academy of Sciences Open access 20 Oct 2010 508
7 Balancing a heterologous mevalonate pathway for improved isoprenoid production in Escherichia coli Douglas J. Pitera, Christopher J. Paddon, Jack D. Newman et al. · Metabolic Engineering 29 Nov 2006 451
8 Complete Reconstitution of a Highly Reducing Iterative Polyketide Synthase Magali Suzanne, Jesse W.-H. Li, Jin Wook Choi et al. · Science Open access 22 Oct 2009 393
9 High-Level Production of Amorpha-4,11-Diene, a Precursor of the Antimalarial Agent Artemisinin, in Escherichia coli Hiroko Tsuruta, Christopher J. Paddon, Diana G. Eng et al. · PLoS ONE Open access 14 Feb 2009 370
10 Methylerythritol Phosphate Pathway of Isoprenoid Biosynthesis Lishan Zhao, Wei‐chen Chang, Youli Xiao et al. · Annual Review of Biochemistry ReviewOpen access 2 Jun 2013 359
11 Efficient Multiplexed Integration of Synergistic Alleles and Metabolic Pathways in Yeasts via CRISPR-Cas Andrew A. Horwitz, Jessica M. Walter, Max G. Schubert et al. · Cell Systems Open access 12 Mar 2015 311
12 De novo sequencing, assembly and analysis of the genome of the laboratory strain Saccharomyces cerevisiae CEN.PK113-7D, a model for modern industrial biotechnology Jurgen F. Nijkamp, Marcel van den Broek, Erwin Datema et al. · Microbial Cell Factories Open access 26 Mar 2012 304
13 Sugarcane (Saccharum X officinarum): A Reference Study for the Regulation of Genetically Modified Cultivars in Brazil Adriana Cheavegatti-Gianotto et al. · Tropical Plant Biology Open access 21 Feb 2011 301
14 Optimization of the mevalonate-based isoprenoid biosynthetic pathway in Escherichia coli for production of the anti-malarial drug precursor amorpha-4,11-diene Jennifer R. Anthony, Larry C. Anthony, Farnaz F. Nowroozi et al. · Metabolic Engineering 13 Aug 2008 295
15 Rapid and Reliable DNA Assembly via Ligase Cycling Reaction Stefan de Kok, Leslie H. Stanton, Todd Slaby et al. · ACS Synthetic Biology 9 Jan 2014 256
16 Investigation of inter- and intraspecies variation through genome sequencing of Aspergillus section Nigri Tammi Vesth et al. · Nature Genetics Open access 17 Oct 2018 239
17 Recent advances in synthetic biology for engineering isoprenoid production in yeast Claudia E. Vickers, Thomas C. Williams, Bingyin Peng et al. · Current Opinion in Chemical Biology Review 15 Jun 2017 209
18 Induction of multiple pleiotropic drug resistance genes in yeast engineered to produce an increased level of anti-malarial drug precursor, artemisinic acid Dae‐Kyun Ro, Mario Ouellet, Eric M. Paradise et al. · BMC Biotechnology Open access 4 Nov 2008 202
19 Identification of Isopentenol Biosynthetic Genes from Bacillus subtilis by a Screening Method Based on Isoprenoid Precursor Toxicity Sydnor T. Withers, Shayin S. Gottlieb, Bonny Lieu et al. · Applied and Environmental Microbiology Open access 11 Aug 2007 194
20 A Novel Semi-biosynthetic Route for Artemisinin Production Using Engineered Substrate-Promiscuous P450 BM3 Jeffrey A. Dietrich, Yasuo Yoshikuni, Karl J. Fisher et al. · ACS Chemical Biology Open access 9 Mar 2009 187
21 De novo genome sequence assembly of a filamentous fungus using Sanger, 454 and Illumina sequence data Scott DiGuistini, Nancy Liao, Darren Platt et al. · Genome biology Open access 11 Sep 2009 159
22 Grand Research Challenges for Sustainable Industrial Biotechnology Adrie J. J. Straathof, A. Wahl, Kirsten R. Benjamin et al. · Trends in biotechnology ReviewOpen access May 2019 153
23 Developing fermentative terpenoid production for commercial usage Michael D. Leavell, Derek J. McPhee, Christopher J. Paddon · Current Opinion in Biotechnology Review 23 Dec 2015 129
24 Microbial production of isoprenoids Sunil S. Chandran, James T. Kealey, Christopher D. Reeves · Process Biochemistry 13 Jun 2011 127
25 Evolutionary instability of CUG-Leu in the genetic code of budding yeasts Tadeusz Krassowski, Aisling Y. Coughlan, Xing‐Xing Shen et al. · Nature Communications Open access 8 May 2018 116
26 Engineering Acetyl Coenzyme A Supply: Functional Expression of a Bacterial Pyruvate Dehydrogenase Complex in the Cytosol of Saccharomyces cerevisiae Barbara U. Kozak, Harmen M. van Rossum, Marijke A. H. Luttik et al. · mBio Open access 22 Oct 2014 113
27 Replacement of the Saccharomyces cerevisiae acetyl-CoA synthetases by alternative pathways for cytosolic acetyl-CoA synthesis Barbara U. Kozak, Harmen M. van Rossum, Kirsten R. Benjamin et al. · Metabolic Engineering Open access 21 Nov 2013 104
28 Approaches and Recent Developments for the Commercial Production of Semi-synthetic Artemisinin Stephanie H. Kung, Sean Lund, Abhishek Murarka et al. · Frontiers in Plant Science Open access 31 Jan 2018 100
29 Determination of the extent of phosphopantetheinylation of polyketide synthases expressed in Escherichia coli and Saccharomyces cerevisiae Ka Kit Michael Lee, Nancy A. Da Silva, James T. Kealey · Analytical Biochemistry 12 Jul 2009 97
30 A self-amplifying RNA vaccine against COVID-19 with long-term room-temperature stability Emily A. Voigt, Alana Gerhardt, Derek Hanson et al. · npj Vaccines Open access 2 Nov 2022 92
31 Sharing Structure and Function in Biological Design with SBOL 2.0 Nicholas Roehner, Jacob Beal, Kevin P. Clancy et al. · ACS Synthetic Biology 25 Apr 2016 89
32 Developing an industrial artemisinic acid fermentation process to support the cost‐effective production of antimalarial artemisinin‐based combination therapies Jacob R. Lenihan, Hiroko Tsuruta, Don Diola et al. · Biotechnology Progress Sep 2008 85
33 High-throughput screening for improved microbial cell factories, perspective and promise Michael D. Leavell, Amoolya H. Singh, Benjamin Kaufmann-Malaga · Current Opinion in Biotechnology ReviewOpen access 9 Sep 2019 79
34 Free mycolic acid accumulation in the cell wall of the mce1 operon mutant strain of Mycobacterium tuberculosis Sally A. Cantrell, Michael D. Leavell, Olivera Marjanovic et al. · The Journal of Microbiology 14 Sep 2013 74
35 Industrial fermentation of renewable diesel fuels Patrick J. Westfall, Timothy S. Gardner · Current Opinion in Biotechnology Review 26 May 2011 71
36 Pat1 promotes processing body assembly by enhancing the phase separation of the DEAD-box ATPase Dhh1 and RNA Ruchika Sachdev, Maria Hondele, Miriam Linsenmeier et al. · eLife Open access 16 Jan 2019 70
37 Use of pantothenate as a metabolic switch increases the genetic stability of farnesene producing Saccharomyces cerevisiae Celeste M. Sandoval, Marites Ayson, Nathan A. Moss et al. · Metabolic Engineering 27 Jul 2014 68
38 Synthetic Biology Open Language Visual (SBOL Visual) Version 2.0 Robert Sidney Cox et al. · Berichte aus der medizinischen Informatik und Bioinformatik/Journal of integrative bioinformatics Open access 19 Mar 2018 68
39 Engineering a functional 1-deoxy-D-xylulose 5-phosphate (DXP) pathway in Saccharomyces cerevisiae James Kirby, Kevin Dietzel, Gale Wichmann et al. · Metabolic Engineering Open access 27 Oct 2016 67
40 Low-Cost, High-Throughput Sequencing of DNA Assemblies Using a Highly Multiplexed Nextera Process Elaine B. Shapland, Victor F. Holmes, Christopher D. Reeves et al. · ACS Synthetic Biology 26 Apr 2015 65
41 High-throughput screening for high-efficiency small-molecule biosynthesis Matthew Rienzo, Shaina J. Jackson, Lawrence K. Chao et al. · Metabolic Engineering Open access 2 Oct 2020 54
42 Developing Commercial Production of Semi-Synthetic Artemisinin, and of β-Farnesene, an Isoprenoid Produced by Fermentation of Brazilian Sugar Kirsten R. Benjamin, Iris R. Silva, João P. Cherubim et al. · Journal of the Brazilian Chemical Society Open access 2016 50
43 Metabolic flux analysis of Shewanella spp. reveals evolutionary robustness in central carbon metabolism Yinjie Tang, Héctor García Martín, Paramvir Dehal et al. · Biotechnology and Bioengineering 24 Sep 2008 49
44 The automated Galaxy-SynBioCAD pipeline for synthetic biology design and engineering Joan Hérisson, Thomas Duigou, Melchior Du et al. · Nature Communications Open access 29 Aug 2022 48
45 Synthetic biology: from hype to impact Timothy S. Gardner · Trends in biotechnology 16 Feb 2013 47
46 Thermal stability of ionic liquids in nitrogen and air environments Yong Ping Huang, Zhichao Chen, Jacob M. Crosthwaite et al. · The Journal of Chemical Thermodynamics Open access 25 Jun 2021 44
47 Comparative study on oxidative treatments of NAPL containing chlorinated ethanes and ethenes using hydrogen peroxide and persulfate in soils Saebom Ko, Michelle L. Crimi, Bruce K. Marvin et al. · Journal of Environmental Management 30 May 2012 44
48 Communicating Structure and Function in Synthetic Biology Diagrams Jacob Beal et al. · ACS Synthetic Biology Open access 26 Jul 2019 43
49 Effective carbon partitioning driven by exotic phloem-specific regulatory elements fused to the Arabidopsis thaliana AtSUC2 sucrose-proton symporter gene Avinash C. Srivastava, Savita Ganesan, Ihab O. Ismail et al. · BMC Plant Biology Open access 20 Jan 2009 43
50 Uncovering secondary metabolite evolution and biosynthesis using gene cluster networks and genetic dereplication Sebastian Theobald, Tammi Vesth, Jakob K. H. Rendsvig et al. · Scientific Reports Open access 12 Dec 2018 42

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.