| 1 |
Targeting Tumor-Associated Macrophages and Inhibition of MCP-1 Reduce Angiogenesis and Tumor Growth in a Human Melanoma Xenograft
Silvina Gazzaniga, Alicia Bravo, Angelo Guglielmotti et al. · Journal of Investigative Dermatology
Open access |
26 Apr 2007 |
302 |
| 2 |
Inhibition of Monocyte Chemotactic Protein-1 Synthesis by Statins
Maria Rosaria Romano, Luisa Diomede, Marina Sironi et al. · Laboratory Investigation
Open access |
Jul 2000 |
299 |
| 3 |
The human microglial HMC3 cell line: where do we stand? A systematic literature review
Cinzia Dello Russo, Natalia Cappoli, Isabella Coletta et al. · Journal of Neuroinflammation
ReviewOpen access |
10 Sep 2018 |
279 |
| 4 |
Rediscovering Trazodone for the Treatment of Major Depressive Disorder
Andrea M. Fagiolini, Alessandro Comandini, Mario Catena Dell’Osso et al. · CNS Drugs
Open access |
13 Oct 2012 |
232 |
| 5 |
Morphological, histochemical and biochemical studies on germ cell mitochondria of normal rats
Cesare De Martino, Aristide Floridi, Maria Luisa Marcante et al. · Cell and Tissue Research
|
1979 |
167 |
| 6 |
New epilepsy therapies in development
Pavel Klein, Rafal M. Kaminski, Matthias J. Koepp et al. · Nature Reviews Drug Discovery
ReviewOpen access |
22 Jul 2024 |
155 |
| 7 |
Protection From Arthritis and Myositis in a Mouse Model of Acute Chikungunya Virus Disease by Bindarit, an Inhibitor of Monocyte Chemotactic Protein-1 Synthesis
Nestor E. Rulli, Michael S. Rolph, Anon Srikiatkhachorn et al. · The Journal of Infectious Diseases
Open access |
Sep 2011 |
145 |
| 8 |
The Chemokine CCL2 Mediates the Seizure-enhancing Effects of Systemic Inflammation
Chiara Cerri, Sacha Genovesi, Manuela Allegra et al. · Journal of Neuroscience
Open access |
30 Mar 2016 |
136 |
| 9 |
Synthesis and anti-ulcer activity of new derivatives of glycyrrhetic, oleanolic and ursolic acids
Carlo Farina, Mario Pinza, GIORGIO PIFFERI · Il Farmaco
|
1998 |
110 |
| 10 |
Targeting monocyte chemotactic protein-1 synthesis with bindarit induces tumor regression in prostate and breast cancer animal models
Massimo Zollo, Valeria Di Dato, Daniela Spano et al. · Clinical & Experimental Metastasis
Open access |
6 Apr 2012 |
109 |
| 11 |
Protein Biomarker Quantification by Immunoaffinity Liquid Chromatography–Tandem Mass Spectrometry: Current State and Future Vision
Hendrik Neubert, Christopher M. Shuford, Timothy V. Olah et al. · Clinical Chemistry
Open access |
16 Jan 2020 |
106 |
| 12 |
Role of MCP-1 in endotoxemia and sepsis
Raina Devi Ramnath, Siaw Wei Ng, Angelo Guglielmotti et al. · International Immunopharmacology
|
21 Mar 2008 |
100 |
| 13 |
Amelioration of alphavirus‐induced arthritis and myositis in a mouse model by treatment with bindarit, an inhibitor of monocyte chemotactic proteins
Nestor E. Rulli, Angelo Guglielmotti, Giorgina Mangano et al. · Arthritis & Rheumatism
|
30 Jul 2009 |
98 |
| 14 |
2019 White Paper on Recent Issues in Bioanalysis: FDA Immunogenicity Guidance, Gene Therapy, Critical Reagents, Biomarkers and Flow Cytometry Validation (Part 3 – Recommendations on 2019 FDA Immunogenicity Guidance, Gene Therapy Bioanalytical Challenges, Strategies for Critical Reagent Management, Biomarker Assay Validation, Flow Cytometry Validation & CLSI H62)
Steven P. Piccoli et al. · Bioanalysis
Open access |
Dec 2019 |
97 |
| 15 |
Practitioner Review: Treatment of chronic insomnia in children and adolescents with neurodevelopmental disabilities
Oliviero Bruni, Marco Angriman, Fabrizio Calisti et al. · Journal of Child Psychology and Psychiatry
|
18 Sep 2017 |
86 |
| 16 |
Saliva from Lutzomyia longipalpis Induces CC Chemokine Ligand 2/Monocyte Chemoattractant Protein-1 Expression and Macrophage Recruitment
Clarissa Teixeira, Maria Jânia Teixeira, Régis Gomes et al. · The Journal of Immunology
|
Dec 2005 |
79 |
| 17 |
Autoradiographic distribution of brain neurokinin-1/substance P receptors using a highly selective ligand [3H]-[Sar9,Met(O2)11]-substance P
Than-Vinh Dam, Biancangela Martinelli, Rémi Quirion · Brain Research
|
Oct 1990 |
77 |
| 18 |
2015 White Paper on Recent Issues in Bioanalysis: Focus on New Technologies and Biomarkers (Part 3 – Lba, Biomarkers and Immunogenicity)
Lakshmi S. Amaravadi et al. · Bioanalysis
Open access |
Dec 2015 |
74 |
| 19 |
Acetaminophen protects hippocampal neurons and PC12 cultures from amyloid β-peptides induced oxidative stress and reduces NF-κB activation
Michela Bisaglia, Valentina Venezia, Patrizia Piccioli et al. · Neurochemistry International
|
Jul 2002 |
71 |
| 20 |
The chemokine monocyte chemoattractant protein-1 contributes to renal dysfunction in swine renovascular hypertension
Xiang-Yang Zhu, Alejandro Chade, James D. Krier et al. · Journal of Hypertension
Open access |
Oct 2009 |
71 |
| 21 |
A Cd/Fe/Zn-Responsive Phytochelatin Synthase is Constitutively Present in the Ancient Liverwort Lunularia cruciata (L.) Dumort
Francesca Degola, Maria De Benedictis, Alessandro Petraglia et al. · Plant and Cell Physiology
Open access |
3 Sep 2014 |
70 |
| 22 |
Pharmacological properties of AF 1161, a new psychotropic drug
Bruno Silvestrini, V. M. Cioli, S Burberi et al. · International Journal of Neuropharmacology
|
Nov 1968 |
70 |
| 23 |
2017 White Paper on Recent Issues in Bioanalysis: A Global Perspective on Immunogenicity Guidelines & Biomarker Assay Performance (Part 3 – Lba: Immunogenicity, Biomarkers and PK Assays)
Shalini Gupta et al. · Bioanalysis
Open access |
Dec 2017 |
69 |
| 24 |
Amelioration of rat adjuvant arthritis by therapeutic treatment with bindarit, an inhibitor of MCP-1 and TNF-α production
Angelo Guglielmotti, E. D’Onofrio, Isabella Coletta et al. · Inflammation Research
|
May 2002 |
69 |
| 25 |
The CCL2 synthesis inhibitor bindarit targets cells of the neurovascular unit, and suppresses experimental autoimmune encephalomyelitis
Shujun Ge, Bandana Shrestha, Debayon Paul et al. · Journal of Neuroinflammation
Open access |
12 Jul 2012 |
64 |
| 26 |
Impact of the anti-inflammatory agent bindarit on the chemokinome: selective inhibition of the monocyte chemotactic proteins.
Massimiliano Mirolo, Marco Fabbri, Marina Sironi et al. · PubMed
|
Sep 2008 |
63 |
| 27 |
Lower Success Rate of Débridement and Implant Retention in Late Acute versus Early Acute Periprosthetic Joint Infection Caused by Staphylococcus spp. Results from a Matched Cohort Study
Marjan Wouthuyzen‐Bakker, Marine Sebillotte, Kaisa Huotari et al. · Clinical Orthopaedics and Related Research
Open access |
25 Feb 2020 |
59 |
| 28 |
Preactivated thiolated glycogen as mucoadhesive polymer for drug delivery
Mara Perrone, Antonio Lopalco, Angela Assunta Lopedota et al. · European Journal of Pharmaceutics and Biopharmaceutics
Open access |
11 Jun 2017 |
59 |
| 29 |
2016 White Paper on Recent Issues in Bioanalysis: Focus on Biomarker Assay Validation (BAV): (Part 3 – Lba, Biomarkers and Immunogenicity)
Susan M. Richards et al. · Bioanalysis
Open access |
18 Nov 2016 |
59 |
| 30 |
Mechanism of the inhibitory effect of melatonin on tumor necrosis factor production in vivo and in vitro
Silvano Sacco, Luciano Aquilini, Pietro Ghezzi et al. · European Journal of Pharmacology
|
Feb 1998 |
59 |
| 31 |
3 Lonidamine and Related Compounds
Bruno Silvestrini, Giuseppe Palazzo, Mauro De Gregorio · Progress in medicinal chemistry
Book chapter |
1985 |
59 |
| 32 |
The anti-inflammatory agent bindarit inhibits neointima formation in both rats and hyperlipidaemic mice
Gianluca Grassia, M. Maddaluno, Angelo Guglielmotti et al. · Cardiovascular Research
Open access |
10 Jul 2009 |
58 |
| 33 |
Identification of Novel Triazole-Based Nicotinamide Phosphoribosyltransferase (NAMPT) Inhibitors Endowed with Antiproliferative and Antiinflammatory Activity
Cristina Travelli et al. · Journal of Medicinal Chemistry
Open access |
6 Feb 2017 |
57 |
| 34 |
2015 White Paper on Recent Issues in Bioanalysis: Focus on New Technologies and Biomarkers (Part 2 – Hybrid LBA/LCMS and Input from Regulatory Agencies)
Brad Ackermann et al. · Bioanalysis
Open access |
Dec 2015 |
56 |
| 35 |
Synthesis, Properties, and Reactions of 1H-Indazol-3-ols and 1,2-Dihydro-3H-indazol-3-ones
Leandro Baiocchi, Giorgio Corsi, Giuseppe Palazzo · Synthesis
|
1978 |
56 |
| 36 |
2018 White Paper on Recent Issues in Bioanalysis: Focus on Flow Cytometry, Gene Therapy, Cut Points and Key Clarifications on Bav (Part 3 – Lba/Cell-Based Assays: Immunogenicity, Biomarkers and Pk Assays)
Lauren F. Stevenson et al. · Bioanalysis
|
29 Nov 2018 |
55 |
| 37 |
New anti-viral drugs for the treatment of the common cold
Caterina Maugeri, Maria Alessandra Alisi, Claudia Apicella et al. · Bioorganic & Medicinal Chemistry
|
9 Jan 2008 |
54 |
| 38 |
INHIBITION OF INFLAMMATORY CYTOKINE PRODUCTION AND PROTECTION AGAINST ENDOTOXIN TOXICITY BY BENZIDAMINE
Marina Sironi, Pietro Pozzi, Nadia Polentarutti et al. · Cytokine
|
Sep 1996 |
54 |
| 39 |
Regulation of the microsomal prostaglandin E synthase-1 in polarized mononuclear phagocytes and its constitutive expression in neutrophils
Michela Mosca, Nadia Polentarutti, Giorgina Mangano et al. · Journal of Leukocyte Biology
|
15 May 2007 |
53 |
| 40 |
Effects of AF3442 [N-(9-ethyl-9H-carbazol-3-yl)-2-(trifluoromethyl)benzamide], a novel inhibitor of human microsomal prostaglandin E synthase-1, on prostanoid biosynthesis in human monocytes in vitro
Annalisa Bruno, Luigia Di Francesco, Isabella Coletta et al. · Biochemical Pharmacology
Open access |
18 Nov 2009 |
52 |
| 41 |
A comparative, randomised, double-blind study of trazodone prolonged-release and paroxetine in the treatment of patients with major depressive disorder
Siegfried F. Kasper, L. Olivieri, Giorgio Di Loreto et al. · Current Medical Research and Opinion
|
17 Jun 2005 |
52 |
| 42 |
Antiproteinuric Effect of Chemokine C-C Motif Ligand 2 Inhibition in Subjects with Acute Proliferative Lupus Nephritis
Alessandro Blè, Marta Mosca, Giorgio Di Loreto et al. · American Journal of Nephrology
Open access |
2011 |
52 |
| 43 |
Selective Induction of MCP-1 in Human Mesangial Cells by the IL-6/sIL-6R Complex
Isabella Coletta, Lucia Soldo, Nadia Polentarutti et al. · Nephron Experimental Nephrology
|
14 Jan 2000 |
51 |
| 44 |
Alpha-Tocopheryl Succinate Inhibits Autophagic Survival of Prostate Cancer Cells Induced by Vitamin K3 and Ascorbate to Trigger Cell Death
Marco Tomasetti, Linda Nocchi, Jiřı́ Neužil et al. · PLoS ONE
Open access |
18 Dec 2012 |
50 |
| 45 |
Effects of MCP-1 Inhibition by Bindarit Therapy in a Rat Model of Polycystic Kidney Disease
Carla Zoja, Daniela Corna, Monica Locatelli et al. · The Nephron journals/Nephron journals
|
17 Dec 2014 |
50 |
| 46 |
A comparative, randomized, double-blind study of trazodone prolonged-release and sertraline in the treatment of major depressive disorder
Carmine Munizza, L. Olivieri, Giorgio Di Loreto et al. · Current Medical Research and Opinion
|
27 Jul 2006 |
50 |
| 47 |
Benzydamine inhibits the release of tumor necrosis factor-α and monocyte chemotactic protein-1 byCandida albicans-stimulated human peripheral blood cells
Marina Sironi, Claudio Milanese, A. Vecchi et al. · International Journal of Clinical & Laboratory Research
|
Dec 1997 |
50 |
| 48 |
Antispermatogenic activity of 1-p. Chlorobenzyl-1H indazol-3-carboxylic acid (AF ) in rats
Cesare De Martino, Mario Stefanini, A. Agrestini et al. · Experimental and Molecular Pathology
|
Oct 1975 |
50 |
| 49 |
Intravenous paracetamol in comparison with ibuprofen for the treatment of patent ductus arteriosus in preterm infants: a randomized controlled trial
Carlo Dani, Gianluca Lista, Silvia Bianchi et al. · European Journal of Pediatrics
Open access |
4 Sep 2020 |
49 |
| 50 |
Lonidamine: A Hyperthermic Sensitizer of HeLa Cells in Culture and of the Meth-A Tumor in vivo
J.H. Kim, Sang Hie Kim, Alan A. Alfieri et al. · Oncology
|
17 Jun 2009 |
49 |