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24 Jun 2013 |
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A Senescence Program Controlled by p53 and p16INK4a Contributes to the Outcome of Cancer Therapy
Clemens A. Schmitt, Jordan S. Fridman, Meng Yang et al. · Cell
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May 2002 |
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Tumour-infiltrating regulatory T cells stimulate mammary cancer metastasis through RANKL–RANK signalling
Wei Phin Tan, Weizhou Zhang, Amy Strasner et al. · Nature
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Feb 2011 |
649 |
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The multiple uses of fluorescent proteins to visualize cancer in vivo
Robert M. Hoffman · Nature reviews. Cancer
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30 Sep 2005 |
617 |
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Orthotopic Metastatic Mouse Models for Anticancer Drug Discovery and Evaluation: a Bridge to the Clinic
Robert M. Hoffman · Investigational New Drugs
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Nov 1999 |
559 |
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Transdifferentiation of glioblastoma cells into vascular endothelial cells
Yasushi Soda, Tomotoshi Marumoto, Dinorah Friedmann‐Morvinski et al. · Proceedings of the National Academy of Sciences
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24 Jan 2011 |
520 |
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Whole-body optical imaging of green fluorescent protein-expressing tumors and metastases
Meng Yang, Eugene A. Baranov, Ping Jiang et al. · Proceedings of the National Academy of Sciences
Open access |
Feb 2000 |
516 |
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Tumor-targeting bacterial therapy with amino acid auxotrophs of GFP-expressing Salmonella typhimurium
Ming Dan Zhao, Meng Yang, Xiaoming Li et al. · Proceedings of the National Academy of Sciences
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11 Jan 2005 |
490 |
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Dissecting p53 tumor suppressor functions in vivo
Clemens A. Schmitt, Jordan S. Fridman, Meng Yang et al. · Cancer Cell
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Apr 2002 |
488 |
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Identification of Liver Cancer Progenitors Whose Malignant Progression Depends on Autocrine IL-6 Signaling
Guobin He, Debanjan Dhar, Hayato Nakagawa et al. · Cell
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Oct 2013 |
485 |
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Biomimetic amplification of nanoparticle homing to tumors
Dmitri Simberg, Tasmia Duza, Ji Ho Park et al. · Proceedings of the National Academy of Sciences
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10 Jan 2007 |
470 |
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Gene expression profiling predicts clinical outcome of prostate cancer
Gennadi V. Glinsky, Anna B. Glinskii, Andrew J. Stephenson et al. · Journal of Clinical Investigation
Open access |
15 Mar 2004 |
467 |
| 13 |
Patient-derived orthotopic xenografts: better mimic of metastasis than subcutaneous xenografts
Robert M. Hoffman · Nature reviews. Cancer
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18 Jun 2015 |
432 |
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Multipotent nestin-positive, keratin-negative hair-follicle bulge stem cells can form neurons
Yasuyuki Amoh, Lingna Li, Kensei Katsuoka et al. · Proceedings of the National Academy of Sciences
Open access |
31 Mar 2005 |
430 |
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A metastatic nude-mouse model of human pancreatic cancer constructed orthotopically with histologically intact patient specimens.
Xinyu Fu, Fiorella Guadagni, Robert M. Hoffman · Proceedings of the National Academy of Sciences
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15 Jun 1992 |
381 |
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Glioma Tumor Stem-Like Cells Promote Tumor Angiogenesis and Vasculogenesis via Vascular Endothelial Growth Factor and Stromal-Derived Factor 1
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8 Sep 2009 |
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Models of human metastatic colon cancer in nude mice orthotopically constructed by using histologically intact patient specimens.
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15 Oct 1991 |
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Implanted hair follicle stem cells form Schwann cells that support repair of severed peripheral nerves
Yasuyuki Amoh, Lingna Li, Raul Campillo et al. · Proceedings of the National Academy of Sciences
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28 Nov 2005 |
326 |
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Imaging exosome transfer from breast cancer cells to stroma at metastatic sites in orthotopic nude-mouse models
Atsushi Suetsugu, Kimi Honma, Shigetoyo Saji et al. · Advanced Drug Delivery Reviews
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17 Aug 2012 |
318 |
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Targeted Therapy with aSalmonella TyphimuriumLeucine-Arginine Auxotroph Cures Orthotopic Human Breast Tumors in Nude Mice
Ming Dan Zhao, Meng Yang, Huaiyu Ma et al. · Cancer Research
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Aug 2006 |
305 |
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Antitumor activity of a homing peptide that targets tumor lymphatics and tumor cells
Pirjo Maarit Laakkonen, Maria E. Åkerman, Hector Biliran et al. · Proceedings of the National Academy of Sciences
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14 Jun 2004 |
279 |
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Development of Real-time Subcellular Dynamic Multicolor Imaging of Cancer-Cell Trafficking in Live Mice with a Variable-Magnification Whole-Mouse Imaging System
Kensuke Yamauchi, Meng Yang, Ping Jiang et al. · Cancer Research
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15 Apr 2006 |
248 |
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Monotherapy with a tumor-targeting mutant of Salmonella typhimurium cures orthotopic metastatic mouse models of human prostate cancer
Ming Dan Zhao, Jack Geller, Huaiyu Ma et al. · Proceedings of the National Academy of Sciences
Open access |
4 Jun 2007 |
245 |
| 24 |
Green fluorescent protein imaging of tumour growth, metastasis, and angiogenesis in mouse models
Robert M. Hoffman · The Lancet Oncology
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Sep 2002 |
244 |
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Potent and Highly Selective Hypoxia-Activated Achiral Phosphoramidate Mustards as Anticancer Drugs
Jian-Xin Duan, Hailong Jiao, Jacob A. Kaizerman et al. · Journal of Medicinal Chemistry
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8 Feb 2008 |
241 |
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Increased Expression of Apoptosis Inhibitor Protein XIAP Contributes to Anoikis Resistance of Circulating Human Prostate Cancer Metastasis Precursor Cells
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15 Mar 2005 |
232 |
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Nascent blood vessels in the skin arise from nestin-expressing hair-follicle cells
Yasuyuki Amoh, Lingna Li, Meng Yang et al. · Proceedings of the National Academy of Sciences
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26 Aug 2004 |
216 |
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Cellular expression of green fluorescent protein, coupled with high-resolution in vivo videomicroscopy, to monitor steps in tumor metastasis
George N. Naumov, Sylvia M. Wilson, Ian C. MacDonald et al. · Journal of Cell Science
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15 Jun 1999 |
214 |
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Whole-body imaging with fluorescent proteins
Robert M. Hoffman, Meng Yang · Nature Protocols
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207 |
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Drug repositioning and repurposing for Alzheimer disease
Clive G. Ballard, Dag Aarsland, Jeffrey L. Cummings et al. · Nature Reviews Neurology
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16 Sep 2020 |
202 |
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The feasibility of targeted selective gene therapy of the hair follicle
Lingna Li, Robert M. Hoffman · Nature Medicine
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Dual-color fluorescence imaging distinguishes tumor cells from induced host angiogenic vessels and stromal cells
Meng Yang, Lingna Li, Ping Jiang et al. · Proceedings of the National Academy of Sciences
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12 Nov 2003 |
198 |
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Development of recombinant methioninase to target the general cancer-specific metabolic defect of methionine dependence: a 40-year odyssey
Robert M. Hoffman · Expert Opinion on Biological Therapy
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2 Dec 2014 |
195 |
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A fluorescent orthotopic bone metastasis model of human prostate cancer.
Meng Yang, Ping X. Jiang, F X Sun et al. · PubMed
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15 Feb 1999 |
194 |
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Human ovarian carcinoma metastatic models constructed in nude mice by orthotopic transplantation of histologically-intact patient specimens.
Xinyu Fu, Richard M. Hoffman · PubMed
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Overexpression and Large-Scale Production of Recombinantl-Methionine-α-deamino-γ-mercaptomethane-lyase for Novel Anticancer Therapy
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4 Jan 2019 |
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Subcellular imaging in the live mouse
Robert M. Hoffman, Meng Yang · Nature Protocols
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Direct external imaging of nascent cancer, tumor progression, angiogenesis, and metastasis on internal organs in the fluorescent orthotopic model
Meng Yang, Eugene A. Baranov, Jinwei Wang et al. · Proceedings of the National Academy of Sciences
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12 Mar 2002 |
184 |
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Color-coded fluorescence imaging of tumor-host interactions
Robert M. Hoffman, Meng Yang · Nature Protocols
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Visualizing gene expression by whole-body fluorescence imaging
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24 Oct 2000 |
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Role of connexins in metastatic breast cancer and melanoma brain colonization
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