Most cited papers from Aptinyx (United States)

Aptinyx (United States)

What are the most cited papers from Aptinyx (United States)?

The most cited paper from Aptinyx (United States) is "Disentangling the Role of Astrocytes in Alcohol Use Disorder" (Louise Adermark, M. Scott Bowers, 2016), with 102 citations. Next come "Idiopathic distal sensory polyneuropathy" (88) and "Autologous CD34 + Cell Therapy for Refractory Angina: 2-Year Outcomes from the ACT34-CMI Study" (68).

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Showing 38 of 38 papers. Every paper is listed.

Most cited papers, sortable by citations and release date
#	Paper
1	Disentangling the Role of Astrocytes in Alcohol Use Disorder Louise Adermark, M. Scott Bowers · Alcoholism Clinical and Experimental Research Open access	Aug 2016	102
2	Idiopathic distal sensory polyneuropathy Roy L. Freeman et al. · Neurology Open access	14 Oct 2020	88
3	Autologous CD34 + Cell Therapy for Refractory Angina: 2-Year Outcomes from the ACT34-CMI Study Timothy D. Henry, Gary L. Schaer, Jay H. Traverse et al. · Cell Transplantation Open access	5 May 2016	68
4	NYX-2925 Is a Novel NMDA Receptor-Specific Spirocyclic-β-Lactam That Modulates Synaptic Plasticity Processes Associated with Learning and Memory M. Amin Khan, David R. Houck, Amanda L. Gross et al. · The International Journal of Neuropsychopharmacology Open access	17 Oct 2017	54
5	Early onset of depression and treatment outcome in patients with major depressive disorder David P. Herzog, Stefanie Wagner, Jan Engelmann et al. · Journal of Psychiatric Research	23 May 2021	53
6	Positive N-Methyl-D-Aspartate Receptor Modulation by Rapastinel Promotes Rapid and Sustained Antidepressant-Like Effects John E. Donello, Pradeep Banerjee, Yong‐Xin Li et al. · The International Journal of Neuropsychopharmacology Open access	13 Jan 2018	51
7	Differential Rearrangement of Excitatory Inputs to the Medial Prefrontal Cortex in Chronic Pain Models Taylor S. Jefferson, Crystle J. Kelly, Marco Martina · Frontiers in Neural Circuits Open access	24 Dec 2021	43
8	Neurovascular plasticity of the hippocampus one week after a single dose of ketamine in genetic rat model of depression Maryam Ardalan, Gregers Wegener, Benedetta Polsinelli et al. · Hippocampus	11 Jul 2016	37
9	Mitochondria Are Critical for BDNF-Mediated Synaptic and Vascular Plasticity of Hippocampus following Repeated Electroconvulsive Seizures Fenghua Chen, Maryam Ardalan, Betina Elfving et al. · The International Journal of Neuropsychopharmacology Open access	5 Dec 2017	32
10	NYX‐458 Improves Cognitive Performance in a Primate Parkinson's Disease Model A Barth, Jay S. Schneider, Tom H. Johnston et al. · Movement Disorders	22 Jan 2020	31
11	NMDAR activation regulates the daily rhythms of sleep and mood Jeffrey S. Burgdorf, Martha Hotz Vitaterna, Christopher J Olker et al. · SLEEP Open access	Aug 2019	30
12	NYX-2925 Is a Novel N-Methyl-d-Aspartate Receptor Modulator that Induces Rapid and Long-Lasting Analgesia in Rat Models of Neuropathic Pain Nayereh S Ghoreishi-Haack, Jessica M. Priebe, Jacqueline D. Aguado et al. · Journal of Pharmacology and Experimental Therapeutics Open access	9 Jul 2018	30
13	Substituted Indazoles as Nav1.7 Blockers for the Treatment of Pain Jennifer M. Frost, David A. DeGoey, Lei Shi et al. · Journal of Medicinal Chemistry Open access	25 Mar 2016	27
14	IGFBP2 Produces Rapid-Acting and Long-Lasting Effects in Rat Models of Posttraumatic Stress Disorder via a Novel Mechanism Associated with Structural Plasticity Jeffrey S. Burgdorf, Elizabeth M. Colechio, Nayereh S Ghoreishi-Haack et al. · The International Journal of Neuropsychopharmacology Open access	30 Jan 2017	26
15	NYX ‐2925, A Novel N‐methyl‐D‐aspartate Receptor Modulator: A First‐in‐Human, Randomized, Double‐blind Study of Safety and Pharmacokinetics in Adults David R. Houck, Laurel Sindelar, Carlos R. Sanabria et al. · Clinical and Translational Science Open access	22 Sep 2018	22
16	A translational EEG-based approach to assess modulation of long-lasting NMDAR-dependent synaptic plasticity Jeffrey S. Burgdorf, Edward P. Christian, Lars Schiøtt Sørensen et al. · Psychopharmacology Open access	7 Aug 2019	21
17	Rat ultrasonic vocalizations as a measure of the emotional component of chronic pain Jeffrey S. Burgdorf, Nayereh S Ghoreishi-Haack, Cassia N. Cearley et al. · Neuroreport	2 Aug 2019	17
18	Rough-and-tumble play induces resilience to stress in rats Jeffrey S. Burgdorf, Roger A. Kroes, Joseph R. Moskal · Neuroreport	28 Sep 2017	16
19	Combinatorial Preconditioning of Rat Brain Cultures with Subprotective Ethanol and Resveratrol Concentrations Promotes Synergistic Neuroprotection Nastaran Khodaie, Nuzhath F. Tajuddin, Robert M. Mitchell et al. · Neurotoxicity Research	12 Mar 2018	15
20	Routinely accessible parameters of mineralocorticoid receptor function, depression subtypes and response prediction: a post-hoc analysis from the early medication change trial in major depressive disorder Jan Engelmann, Harald Murck, Stefanie Wagner et al. · The World Journal of Biological Psychiatry	5 Jan 2022	9
21	NYX‐2925 induces metabotropic N ‐methyl‐ d ‐aspartate receptor (NMDAR) signaling that enhances synaptic NMDAR and α‐amino‐3‐hydroxy‐5‐methyl‐4‐isoxazolepropionic acid receptor M. Scott Bowers, Luisa P. Cacheaux, Srishti U. Sahu et al. · Journal of Neurochemistry Open access	3 Aug 2019	9
22	Are There Reasons to Fear Anxiety Screening? Murray B. Stein, Linda L. Hill · JAMA	20 Jun 2023	6
23	Impact of a G-CSF Policy to Reduce Low-Value Care on Guideline Adherence and Mortality Chinelo Orji, Carolyn M. Brown, John Russell Hoverman et al. · JCO Oncology Practice Open access	14 Apr 2021	5
24	NYX-2925, A NOVEL, NON-OPIOID, SMALL-MOLECULE MODULATOR OF THE N-METHYL-d-ASPARTATE RECEPTOR (NMDAR), DEMONSTRATES POTENTIAL TO TREAT CHRONIC, SUPRASPINAL CENTRALIZED PAIN CONDITIONS Jessica Marie Gajda, Marina N. Asiedu, Gladys Morrison et al. · Medicine in Drug Discovery Open access	25 Nov 2020	5
25	The NMDAR modulator NYX-2925 alleviates neuropathic pain via a Src-dependent mechanism in the mPFC Gladys Morrison, Marina N. Asiedu, Jessica M. Priebe et al. · Neurobiology of Pain Open access	3 Dec 2019	5
26	Rat 22-kHz Ultrasonic Vocalizations as a Measure of Emotional Set Point During Social Interactions Jeffrey S. Burgdorf, Jaak Panksepp, Joseph R. Moskal · Handbook of behavioral neuroscience Book chapter	2018	5
27	Effects of Rapastinel (Formerly GLYX-13) on Serum Brain-Derived Neurotrophic Factor in Obsessive-Compulsive Disorder Omer Linkovski, Hanyang Shen, Jordana Zwerling et al. · The Journal of Clinical Psychiatry Open access	20 Feb 2018	5
28	853. Effect of a Novel NMDA Receptor Modulator, Rapastinel (formerly GLYX-13) in OCD: Proof-Of-Concept Carolyn I. Rodriguez, Jordana Zwerling, Eyal Kalanthroff et al. · Biological Psychiatry	29 Apr 2017	4
29	Towards the Molecular Foundations of Glutamatergic-targeted Antidepressants Roger A. Kroes, Carol L. Nilsson · Current Neuropharmacology Open access	10 Mar 2016	4
30	The Neurobiology of Childhood Trauma - Aldosterone and Blood Pressure Changes in a Community Sample Jan Terock, Anke Hannemann, Johanna Klinger-Koenig et al. · Biological Psychiatry	28 Apr 2022	3
31	(409) A Double-Blind, Placebo-Controlled, Phase 2 Study to Assess the Safety and Efficacy of NYX-2925 in Subjects with Painful Diabetic Peripheral Neuropathy Sarah A. Torri, Stephen M. Sainati, Mustafa Burak et al. · Journal of Pain Open access	21 Mar 2019	3
32	NYX-783, A Novel Positive Allosteric Modulator of the N-Methyl D-Aspartate Receptor, Increases NMDAR-Mediated Signaling in the Infralimbic Prefrontal Cortex to Facilitate Extinction Learning in PTSD-Relevant Rodent Models A Barth · Biological Psychiatry	28 Apr 2022	2
33	NYX-2925, a novel N-methyl-D-aspartate Receptor Positive Allosteric-Modulator, showed antinociceptive Activity in functional Neuroimaging evaluations correlated with improved Patient reported Pain and Fibromyalgia Symptoms (P1-4.001) Harald Murck, Steven E. Harte, Tony E. Larkin et al. · Neurology	3 May 2022	1
34	Rationale for Quantification in Nursing Services Using the International Council of Nurses Nurse-Patient Summary Edward J. Halloran, Welton John, Bastin H. Lee et al. · Studies in health technology and informatics Book chapter	2016	1
35	Insights from system dynamics that support experimental research: an exemplar of the NMDA receptor Crystle J. Kelly, James R. Rogers, Edward J. Gallaher · System Dynamics Review	Apr 2021	0
36	A Randomized, Placebo-Controlled, Double-Blind Study of NYX-783 in Patients With Post-traumatic Stress Disorder Lori L. Davis, Murray B. Stein, Lesley M. Arnold et al. · Biological Psychiatry	27 Apr 2021	0
37	NYX-2925, a NMDA receptor modulator, shows efficacy in the rat taxol chemotherapy-induced peripheral neuropathy model Nayereh S Ghoreishi-Haack, J. Priebe, Jacqueline D. Aguado et al. · Journal of Pain Open access	13 Feb 2018	0
38	(198) NYX-2925, a NMDA receptor glycine site functional partial agonist, shows efficacy in neuropathic pain that is NMDA and AMPA receptor dependent and appears to be driven through brain, but not spinal, circuitry Nayereh S Ghoreishi-Haack, Elizabeth M. Colechio, J. Priebe et al. · Journal of Pain Open access	31 Mar 2017	0

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.