Most cited papers from Aptuit (Italy)

Aptuit (Italy)

What are the most cited papers from Aptuit (Italy)?

The most cited paper from Aptuit (Italy) is "A novel antibiotic class targeting the lipopolysaccharide transporter" (Claudia Zampaloni et al., 2024), with 310 citations. Next come "The Ca V 3.3 calcium channel is the major sleep spindle pacemaker in thalamus" (218) and "Recognition and Alleviation of Pain in Laboratory Animals" (201).

Published TypeFieldAccessCitations

Showing 50 of 61 papers. Every paper with more than 25 citations is listed.

Most cited papers, sortable by citations and release date
#	Paper
1	A novel antibiotic class targeting the lipopolysaccharide transporter Claudia Zampaloni et al. · Nature Open access	3 Jan 2024	310
2	The Ca V 3.3 calcium channel is the major sleep spindle pacemaker in thalamus Simone Astori, Ralf Dieter Wimmer, Haydn M. Prosser et al. · Proceedings of the National Academy of Sciences Open access	Aug 2011	218
3	Recognition and Alleviation of Pain in Laboratory Animals Ana Criado · Laboratory Animals	25 Aug 2010	201
4	Bisdemethylcurcumin and structurally related hispolon analogues of curcumin exhibit enhanced prooxidant, anti-proliferative and anti-inflammatory activities in vitro Jayaraj Ravindran, Gottumukkala Venkata Subbaraju, Modukuri V. Ramani et al. · Biochemical Pharmacology Open access	5 Feb 2010	114
5	Cross-disease analysis of Alzheimer’s disease and type-2 Diabetes highlights the role of autophagy in the pathophysiology of two highly comorbid diseases Laura Caberlotto, Thanh-Phuong Nguyen, Mario Lauria et al. · Scientific Reports Open access	8 Mar 2019	96
6	Classification and reporting of severity experienced by animals used in scientific procedures: FELASA/ECLAM/ESLAV Working Group report David W. Smith, David Anderson, Anne‐Dominique A. Y. Degryse et al. · Laboratory Animals Open access	23 Jan 2018	89
7	Thiophene antibacterials that allosterically stabilize DNA-cleavage complexes with DNA gyrase Pan F. Chan, Thomas RM Germe, B.D. Bax et al. · Proceedings of the National Academy of Sciences Open access	15 May 2017	86
8	Molecular Insights into Function and Competitive Inhibition of Pseudomonas aeruginosa Multiple Virulence Factor Regulator Tomoe Kitao, Francois L. Lepine, Seda Babloudi et al. · mBio Open access	15 Jan 2018	80
9	Tuft cell-derived acetylcholine promotes epithelial chloride secretion and intestinal helminth clearance Tyler E. Billipp, Connie Fung, Lily M. Webeck et al. · Immunity Open access	13 May 2024	72
10	Social defeat and isolation induce clear signs of a depression-like state, but modest cardiac alterations in wild-type rats Luca Carnevali, Francesca Mastorci, Gallia Graiani et al. · Physiology & Behavior	7 Feb 2012	69
11	A Novel Modulator of Kv3 Potassium Channels Regulates the Firing of Parvalbumin-Positive Cortical Interneurons Marcelo D. Rosato‐Siri, Erika Zambello, Chiara Mutinelli et al. · Journal of Pharmacology and Experimental Therapeutics	17 Jun 2015	69
12	Asymmetric Palladium‐Catalyzed Allylic Alkylation Using Dialkylzinc Reagents: A Remarkable Ligand Effect Antonio Misale, Supaporn Niyomchon, Marco Luparia et al. · Angewandte Chemie International Edition	28 May 2014	68
13	Interlaboratory study for the evaluation of three microtiter plate-based biofilm quantification methods Jontana Allkja, Frits van Charante, Juliana Aizawa et al. · Scientific Reports Open access	2 Jul 2021	65
14	MPX-004 and MPX-007: New Pharmacological Tools to Study the Physiology of NMDA Receptors Containing the GluN2A Subunit Robert A. Volkmann, Christopher M. Fanger, David R. Anderson et al. · PLoS ONE Open access	Feb 2016	65
15	The mGluR2/3 Agonist LY379268 Induced Anti-Reinstatement Effects in Rats Exhibiting Addiction-like Behavior Nazzareno Cannella, Briac Halbout, Stefanie Uhrig et al. · Neuropsychopharmacology Open access	29 Apr 2013	64
16	Polyphenols and Their Formulations Ortensia Ilaria Parisi, Francesco Puoci, Donatella Restuccia et al. · Polyphenols in Human Health and Disease Book chapter	Nov 2013	62
17	Impact ofSLCO1B1(OATP1B1) andABCG2(BCRP) genetic polymorphisms and inhibition on LDL-C lowering and myopathy of statins Grant T. Generaux, Fiorenza M. Bonomo, Marta Johnson et al. · Xenobiotica	22 Mar 2011	61
18	Inhibition of the Casein-Kinase-1-Epsilon/Delta Prevents Relapse-Like Alcohol Drinking Stéphanie Perreau‐Lenz, Valentina Vengeliene, Hamid R. Noori et al. · Neuropsychopharmacology Open access	2 May 2012	60
19	Transcriptomic Profiling Discloses Molecular and Cellular Events Related to Neuronal Differentiation in SH-SY5Y Neuroblastoma Cells Francesco Pezzini, Laura Bettinetti, Francesca Di Leva et al. · Cellular and Molecular Neurobiology Open access	15 Jul 2016	57
20	Familial Alzheimer’s disease-linked presenilin mutants and intracellular Ca2+ handling: A single-organelle, FRET-based analysis Elisa Greotti, Paola Capitanio, Andrea Wong et al. · Cell Calcium Open access	25 Feb 2019	55
21	pH-responsive chitosan based hydrogels affect the release of dapsone: Design, set-up, and physicochemical characterization Luíse Lopes Chaves, Alessandro Silveri, Alexandre C.C. Vieira et al. · International Journal of Biological Macromolecules	26 Apr 2019	54
22	Selective Inhibitors of G2019S-LRRK2 Kinase Activity Albert William Garofalo et al. · Journal of Medicinal Chemistry Open access	16 Nov 2020	48
23	Tackling recalcitrant Pseudomonas aeruginosa infections in critical illness via anti-virulence monotherapy Vijay Kumar Singh, Marianna Almpani, Damien Maura et al. · Nature Communications Open access	30 Aug 2022	47
24	Recent Advances in the Development of Dopamine D 3 Receptor Antagonists: a Medicinal Chemistry Perspective Fabrizio Micheli · ChemMedChem	18 Mar 2011	46
25	Design, synthesis and evaluation of benzothiazole derivatives as multifunctional agents Ernestine Nicaise Djuidje, Sabrina Sciabica, Raissa Buzzi et al. · Bioorganic Chemistry Open access	2 Jun 2020	43
26	Pharmacokinetics-Pharmacodynamics of Enmetazobactam Combined with Cefepime in a Neutropenic Murine Thigh Infection Model Fabian Bernhard, Rajesh Odedra, Sylvie Sordello et al. · Antimicrobial Agents and Chemotherapy Open access	2 Apr 2020	43
27	Polypharmacology Approaches against the Pseudomonas aeruginosa MvfR Regulon and Their Application in Blocking Virulence and Antibiotic Tolerance Damien Maura, Steffen Lorenz Drees, Arunava Bandyopadhaya et al. · ACS Chemical Biology Open access	5 Apr 2017	43
28	Spontaneous Cardiomyopathy in Young Sprague-Dawley Rats Franck Jacques-Antoine Chanut, Carie Kimbrough, Rick Hailey et al. · Toxicologic Pathology Open access	7 Mar 2013	43
29	Dopamine D3 receptor antagonists: a patent review (2007 – 2012) Fabrizio Micheli, Christian A. Heidbreder · Expert Opinion on Therapeutic Patents	3 Jan 2013	43
30	Pharmacodynamics of Cefepime Combined with the Novel Extended-Spectrum-β-Lactamase (ESBL) Inhibitor Enmetazobactam for Murine Pneumonia Caused by ESBL-Producing Klebsiella pneumoniae Adam J. Johnson, Laura McEntee, Nicola Farrington et al. · Antimicrobial Agents and Chemotherapy Open access	2 Apr 2020	41
31	OMN6 a novel bioengineered peptide for the treatment of multidrug resistant Gram negative bacteria Shira Mandel, Janna Michaeli, Noa Nur et al. · Scientific Reports Open access	23 Mar 2021	40
32	Predictive Elution Window Stretching and Shifting as a Generic Search Strategy for Automated Method Development for Liquid Chromatography Eva Tyteca, Anuschka Liekens, David Clicq et al. · Analytical Chemistry Open access	20 Aug 2012	40
33	In Vitro Measurement of Drug Efficiency Index to Aid Early Lead Optimization Klara Livia Valko, Elisabetta Chiarparin, Shenaz Nunhuck et al. · Journal of Pharmaceutical Sciences	28 Aug 2012	40
34	Design, synthesis and biological evaluation of novel vicinal diaryl-substituted 1H-Pyrazole analogues of combretastatin A-4 as highly potent tubulin polymerization inhibitors Romeo Romagnoli, Paola Oliva, María Kimatrai Salvador et al. · European Journal of Medicinal Chemistry Open access	Aug 2019	38
35	Plasma protein binding and blood-free concentrations: which studies are needed to develop a drug? Mario Pellegatti, Sabrina Pagliarusco, Lara Solazzo et al. · Expert Opinion on Drug Metabolism & Toxicology	2 Jun 2011	38
36	Mouse pneumonia model by Acinetobacter baumannii multidrug resistant strains: Comparison between intranasal inoculation, intratracheal instillation and oropharyngeal aspiration techniques Gabriella Bergamini, Maria Elisa Perico, Stefano Di Palma et al. · PLoS ONE Open access	2 Dec 2021	37
37	New Tools to Study Astrocyte Ca2+ Signal Dynamics in Brain Networks In Vivo Gabriele Losi, Letizia Mariotti, Michele Sessolo et al. · Frontiers in Cellular Neuroscience Open access	9 May 2017	37
38	Intrapulmonary Pharmacokinetics of Cefepime and Enmetazobactam in Healthy Volunteers: Towards New Treatments for Nosocomial Pneumonia Shampa Das, Richard J. Fitzgerald, Asad Ullah et al. · Antimicrobial Agents and Chemotherapy Open access	20 Oct 2020	36
39	Antimanic Efficacy of a Novel Kv3 Potassium Channel Modulator Puja K. Parekh, Michelle M. Sidor, Andrea G. Gillman et al. · Neuropsychopharmacology Open access	31 Aug 2017	35
40	The perils with the misuse of predictive power Nigel S. Dallow, Paolo Fina · Pharmaceutical Statistics	20 Oct 2010	34
41	Highly Pluripotent Adipose-Derived Stem Cell–Enriched Nanofat: A Novel Translational System in Stem Cell Therapy Lindsey Alejandra Quintero Sierra, Reetuparna Biswas, Anita Conti et al. · Cell Transplantation Open access	2023	33
42	Folding intermediate states of the parallel human telomeric G-quadruplex DNA explored using Well-Tempered Metadynamics Roberta Rocca, Ferruccio Palazzesi, Jussara Amato et al. · Scientific Reports Open access	21 Feb 2020	33
43	The Use Of N-Methylpyrrolidone as a Cosolvent and Oxidant in Pharmaceutical Stress Testing Dan W. Reynolds, Marina Galvani, Simon R. Hicks et al. · Journal of Pharmaceutical Sciences	15 Nov 2011	33
44	Stable expression and functional characterization of a human nicotinic acetylcholine receptor with α6β2 properties: discovery of selective antagonists Anna Maria Capelli, Laura Castelletti, Yu Hua Chen et al. · British Journal of Pharmacology Open access	14 Jan 2011	33
45	Characterization of three diaminopyrimidines as potent and selective antagonists of P2X3 and P2X2/3 receptors within vivoefficacy in a pain model Elisa Ballini, Caterina Virginio, SJ Medhurst et al. · British Journal of Pharmacology Open access	15 Mar 2011	32
46	Esmethadone-HCl (REL-1017): a promising rapid antidepressant Maurizio Fava, Stephen M. Stahl, Sara De Martin et al. · European Archives of Psychiatry and Clinical Neuroscience Open access	8 Mar 2023	31
47	Review on Canine Oral Melanoma: An Undervalued Authentic Genetic Model of Human Oral Melanoma? Stefano Di Palma, Ashleigh McConnell, Sara Verganti et al. · Veterinary Pathology	9 Mar 2021	31
48	Development of the first in vivo GPR17 ligand through an iterative drug discovery pipeline: A novel disease-modifying strategy for multiple sclerosis Chiara Parravicini, Davide Lecca, Davide Marangon et al. · PLoS ONE Open access	22 Apr 2020	31
49	A Contribution to the Harmonization of Non-targeted NMR Methods for Data-Driven Food Authenticity Assessment Vito Leonardo Gallo et al. · Food Analytical Methods Open access	26 Nov 2019	31
50	Bifidobacterium aesculapii sp. nov., from the faeces of the baby common marmoset (Callithrix jacchus) Monica Modesto, Samanta Michelini, Ilaria Stefanini et al. · INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY	28 May 2014	31

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.