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Institution · Ariadne Diagnostics (United States)

Most cited papers from Ariadne Diagnostics (United States)

Ariadne Diagnostics (United States)

What are the most cited papers from Ariadne Diagnostics (United States)?

The most cited paper from Ariadne Diagnostics (United States) is "Global Surgery 2030: evidence and solutions for achieving health, welfare, and economic development" (John Gerard Meara et al., 2015), with 3,853 citations. Next come "Integrins and Signal Transduction Pathways: the Road Taken" (2,983) and "CELLULAR FUNCTIONS REGULATED BY SRC FAMILY KINASES" (2,512).

Showing 50 of 57 papers. Every paper with more than 162 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 Global Surgery 2030: evidence and solutions for achieving health, welfare, and economic development John Gerard Meara et al. · The Lancet Open access 26 Apr 2015 3,853
2 Integrins and Signal Transduction Pathways: the Road Taken Edwin A. Clark, Joan S. Brugge · Science 14 Apr 1995 2,983
3 CELLULAR FUNCTIONS REGULATED BY SRC FAMILY KINASES Sheila M. Thomas, Joan S. Brugge · Annual Review of Cell and Developmental Biology Review Nov 1997 2,512
4 AP24534, a Pan-BCR-ABL Inhibitor for Chronic Myeloid Leukemia, Potently Inhibits the T315I Mutant and Overcomes Mutation-Based Resistance Thomas O’Hare et al. · Cancer Cell Open access Nov 2009 1,265
5 Cloning the Soil Metagenome: a Strategy for Accessing the Genetic and Functional Diversity of Uncultured Microorganisms Michelle R. Rondon, Paul R. August, Alan D. Bettermann et al. · Applied and Environmental Microbiology Open access Jun 2000 1,250
6 Structural basis for the binding of proline-rich peptides to SH3 domains Hongtao Yu, James Chen, Sibo Feng et al. · Cell Mar 1994 1,020
7 Association of the Shc and Grb2/Sem5 SH2-containing proteins is implicated in activation of the Ras pathway by tyrosine kinases Maria Rozakis-Adcock, Jane C. McGlade, Geraldine Mbamalu et al. · Nature Dec 1992 996
8 Estimate of the global volume of surgery in 2012: an assessment supporting improved health outcomes Thomas G. Weiser, Alex Bernard Haynes, George Molina et al. · The Lancet Open access Apr 2015 984
9 DNA hypomethylation leads to elevated mutation rates Richard Z. Chen, Ulf Pettersson, Caroline Beard et al. · Nature Sep 1998 962
10 Ponatinib in Refractory Philadelphia Chromosome–Positive Leukemias Jörge E. Cortes, Hagop M. Kantarjian, Neil P. Shah et al. · New England Journal of Medicine Open access 28 Nov 2012 780
11 Pathway studio—the analysis and navigation of molecular networks Alexander P. Nikitin, Sergei Egorov, Nikolai Daraselia et al. · Bioinformatics Open access Nov 2003 684
12 Relationship Between Cesarean Delivery Rate and Maternal and Neonatal Mortality George Molina, Thomas G. Weiser, Stuart R. Lipsitz et al. · JAMA Open access Dec 2015 637
13 Methane oxidation by an extremely acidophilic bacterium of the phylum Verrucomicrobia Peter F. Dunfield, Anton Yuryev, Pavel Senin et al. · Nature 14 Nov 2007 603
14 Hypoxic induction of human vascular endothelial growth factor expression through c-Src activation Debabrata Mukhopadhyay, Leonidas Tsiokas, Xiao-Mai Zhou et al. · Nature Jun 1995 598
15 A humanized system for pharmacologic control of gene expression Victor M. Rivera, Tim Clackson, Sridaran Natesan et al. · Nature Medicine Sep 1996 549
16 Therapeutic strategies to overcome crizotinib resistance in non-small cell lung cancers harboring the fusion oncogene EML4-ALK Ryohei Katayama, Tahsin M. Khan, Cyril H. Benes et al. · Proceedings of the National Academy of Sciences Open access 18 Apr 2011 543
17 Phosphatidylinositol 3-Kinase Is Required for Integrin-Stimulated AKT and Raf-1/Mitogen-Activated Protein Kinase Pathway Activation Warren G. King, Mark D. Mattaliano, Tung O. Chan et al. · Molecular and Cellular Biology Open access Aug 1997 431
18 Insulin Stimulates Adipogenesis through the Akt-TSC2-mTORC1 Pathway Huihui Zhang, Jingxiang Huang, Katrin Düvel et al. · PLoS ONE Open access 9 Jul 2009 405
19 Noninvasive prenatal detection and selective analysis of cell-free DNA obtained from maternal blood: evaluation for trisomy 21 and trisomy 18 Andrew B. Sparks, Craig A. Struble, Eric T. Wang et al. · American Journal of Obstetrics and Gynecology 26 Jan 2012 396
20 Controlled Dimerization of ErbB Receptors Provides Evidence for Differential Signaling by Homo- and Heterodimers Senthil K. Muthuswamy, Michael Gilman, Joan S. Brugge · Molecular and Cellular Biology Open access Oct 1999 367
21 Discovery of 3-[2-(Imidazo[1,2-b]pyridazin-3-yl)ethynyl]-4-methyl-N-{4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl}benzamide (AP24534), a Potent, Orally Active Pan-Inhibitor of Breakpoint Cluster Region-Abelson (BCR-ABL) Kinase Including the T315I Gatekeeper Mutant Wei‐Sheng Huang et al. · Journal of Medicinal Chemistry Open access Jun 2010 366
22 Activity and safety of brigatinib in ALK-rearranged non-small-cell lung cancer and other malignancies: a single-arm, open-label, phase 1/2 trial Scott N. Gettinger, Lyudmila A. Bazhenova, Corey Jay Langer et al. · The Lancet Oncology 8 Nov 2016 355
23 Molecular basis for interaction of the protein tyrosine kinase ZAP-70 with the T-cell receptor Marcos H. Hatada, Xiaode Lu, Ellen R. Laird et al. · Nature 7 Sep 1995 353
24 Regulation of Protein Secretion Through Controlled Aggregation in the Endoplasmic Reticulum Victor M. Rivera, Xiurong Wang, Scott Wardwell et al. · Science 4 Feb 2000 351
25 The Potent ALK Inhibitor Brigatinib (AP26113) Overcomes Mechanisms of Resistance to First- and Second-Generation ALK Inhibitors in Preclinical Models Sen Zhang et al. · Clinical Cancer Research Open access 25 Oct 2016 332
26 Ponatinib (AP24534), a Multitargeted Pan-FGFR Inhibitor with Activity in Multiple FGFR-Amplified or Mutated Cancer Models Joseph M. Gozgit, Matthew J. Wong, Lauren E. Moran et al. · Molecular Cancer Therapeutics Open access 12 Jan 2012 324
27 Managing COVID-19 in Surgical Systems Mary Elizabeth Brindle, Atul A. Gawande · Annals of Surgery Open access 27 Mar 2020 322
28 Achieving Goal-Concordant Care: A Conceptual Model and Approach to Measuring Serious Illness Communication and Its Impact Justin J. Sanders, J. Randall Curtis, James A. Tulsky · Journal of Palliative Medicine Open access Nov 2017 318
29 Draft genome sequence of the rubber tree Hevea brasiliensis Ahmad Yamin Abdul Rahman et al. · BMC Genomics Open access 2 Feb 2013 282
30 Accurate whole-genome sequencing and haplotyping from 10 to 20 human cells Brock A. Peters et al. · Nature Open access Jul 2012 279
31 Selective analysis of cell‐free DNA in maternal blood for evaluation of fetal trisomy Andrew B. Sparks, Eric T. Wang, Craig A. Struble et al. · Prenatal Diagnosis Open access 2012 267
32 Ponatinib versus imatinib for newly diagnosed chronic myeloid leukaemia: an international, randomised, open-label, phase 3 trial Jeffrey Howard Lipton et al. · The Lancet Oncology 12 Apr 2016 264
33 mTOR-Raptor Binds and Activates SGK1 to Regulate p27 Phosphorylation Feng Hong, Michelle D. Larrea, Cheryl A. Doughty et al. · Molecular Cell Open access Jun 2008 264
34 Calcium influx induces neurite growth through a Src-Ras signaling cassette Gabriel Rusanescu, Haiqing Qi, Sheila M. Thomas et al. · Neuron Open access Dec 1995 261
35 Identification of Src, Fyn, Lyn, PI3K and Abl SH3 domain ligands using phage display libraries. Richard J. Rickles, Martyn C. Botfield, Zhigang Weng et al. · The EMBO Journal Open access Dec 1994 259
36 Measurement of the binding of tyrosyl phosphopeptides to SH2 domains: a reappraisal. John Edward Ladbury, Mark A. Lemmon, M Zhou et al. · Proceedings of the National Academy of Sciences Open access 11 Apr 1995 254
37 Platelet-Derived Growth Factor Induces Phosphorylation of Multiple JAK Family Kinases and STAT Proteins Marie‐Luce Vignais, Henry B. Sadowski, Diane Watling et al. · Molecular and Cellular Biology Open access Apr 1996 249
38 Phase II Study of the Mammalian Target of Rapamycin Inhibitor Ridaforolimus in Patients With Advanced Bone and Soft Tissue Sarcomas Sant P. Chawla, Arthur P. Staddon, Laurence H. Baker et al. · Journal of Clinical Oncology Open access 8 Nov 2011 248
39 MedScan, a natural language processing engine for MEDLINE abstracts Svetlana Novichkova, Sergei Egorov, Nikolai Daraselia · Bioinformatics Open access Sep 2003 244
40 Extracting human protein interactions from MEDLINE using a full-sentence parser Nikolai Daraselia, Anton Yuryev, Sergei Egorov et al. · Bioinformatics Open access 22 Jan 2004 242
41 Tandem SH2 Domains Confer High Specificity in Tyrosine Kinase Signaling Elizabeth A. Ottinger, Martyn C. Botfield, Steven E. Shoelson · Journal of Biological Chemistry Open access 1998 237
42 Identification of Src, Fyn, and Lyn SH3-binding proteins: implications for a function of SH3 domains. Zhen Weng, Sheila M. Thomas, Richard J. Rickles et al. · Molecular and Cellular Biology Open access Jul 1994 235
43 Frequency of Germline Mutations in Cancer Susceptibility Genes in Malignant Mesothelioma Vasiliki Panou et al. · Journal of Clinical Oncology Open access 16 Aug 2018 232
44 Detection of Src homology 3-binding proteins, including paxillin, in normal and v-Src-transformed Balb/c 3T3 cells Zhigang Weng, Jacqueline A. Taylor, Christopher E. Turner et al. · Journal of Biological Chemistry Open access Jul 1993 219
45 Development of a clinical polygenic risk score assay and reporting workflow Limin Hao, Peter Kraft, Gabriel F. Berriz et al. · Nature Medicine Open access 18 Apr 2022 207
46 Syk Is Activated by Phosphotyrosine-containing Peptides Representing the Tyrosine-based Activation Motifs of the High Affinity Receptor for IgE Lily Shiue, Mark J. Zoller, Joan S. Brugge · Journal of Biological Chemistry Open access May 1995 202
47 Inhibition of wild-type and mutant Bcr-Abl by AP23464, a potent ATP-based oncogenic protein kinase inhibitor: implications for CML Thomas O’Hare, Roy M. Pollock, Eric P. Stoffregen et al. · Blood Open access 16 Jul 2004 201
48 A Fas-based suicide switch in human T cells for the treatment of graft-versus-host disease Daniel C. Thomis · Blood Mar 2001 200
49 Polygenic risk scores in the clinic: new perspectives needed on familiar ethical issues Anna C. F. Lewis, Robert C. Green · Genome Medicine Open access 28 Jan 2021 192
50 Phage display selection of ligand residues important for Src homology 3 domain binding specificity. Richard J. Rickles, Martyn C. Botfield, Xiaoming Zhou et al. · Proceedings of the National Academy of Sciences Open access 21 Nov 1995 189

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.