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Most cited papers from Arrien Pharmaceuticals (United States)

What are the most cited papers from Arrien Pharmaceuticals (United States)?

The most cited paper from Arrien Pharmaceuticals (United States) is "Towards the sustainable discovery and development of new antibiotics" (Marcus Miethke et al., 2021), with 1,192 citations. Next come "Calcimimetics with potent and selective activity on the parathyroid calcium receptor" (616) and "Molecular Cloning and Functional Expression of Human Parathyroid Calcium Receptor cDNAs" (504).

Showing 50 of 60 papers. Every paper with more than 56 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 Towards the sustainable discovery and development of new antibiotics Marcus Miethke et al. · Nature Reviews Chemistry ReviewOpen access 19 Aug 2021 1,192
2 Calcimimetics with potent and selective activity on the parathyroid calcium receptor Edward F. Nemeth, Michael E. Steffey, Lance G. Hammerland et al. · Proceedings of the National Academy of Sciences Open access 31 Mar 1998 616
3 Molecular Cloning and Functional Expression of Human Parathyroid Calcium Receptor cDNAs James E. Garrett, Irene V. Capuano, Lance G. Hammerland et al. · Journal of Biological Chemistry Open access May 1995 504
4 Expression and Characterization of Inactivating and Activating Mutations in the Human Ca2+-sensing Receptor Mei Bai, Steven J. Quinn, Sunita Trivedi et al. · Journal of Biological Chemistry Open access Aug 1996 430
5 Controlled Dimerization of ErbB Receptors Provides Evidence for Differential Signaling by Homo- and Heterodimers Senthil K. Muthuswamy, Michael Gilman, Joan S. Brugge · Molecular and Cellular Biology Open access Oct 1999 367
6 Identification of a Peptide Toxin fromGrammostola spatulataSpider Venom That Blocks Cation-Selective Stretch-Activated Channels Thomas M. Suchyna, JANICE H. JOHNSON, Katherine Hamer et al. · The Journal of General Physiology Open access May 2000 352
7 Antagonizing the parathyroid calcium receptor stimulates parathyroid hormone secretion and bone formation in osteopenic rats Maxine Gowen, George B. Stroup, Robert A. Dodds et al. · Journal of Clinical Investigation Open access Jun 2000 282
8 Short-Term Inhibition of Parathyroid Hormone Secretion by a Calcium-Receptor Agonist in Patients with Primary Hyperparathyroidism Shonni J. Silverberg, Henry G. Bone, Thomas B. Marriott et al. · New England Journal of Medicine 20 Nov 1997 260
9 Platelet-Derived Growth Factor Induces Phosphorylation of Multiple JAK Family Kinases and STAT Proteins Marie‐Luce Vignais, Henry B. Sadowski, Diane Watling et al. · Molecular and Cellular Biology Open access Apr 1996 249
10 Calcilytic Compounds: Potent and Selective Ca2+Receptor Antagonists That Stimulate Secretion of Parathyroid Hormone Edward F. Nemeth, Eric G. DelMar, William L. Heaton et al. · Journal of Pharmacology and Experimental Therapeutics Oct 2001 238
11 Identification and localization of extracellular Ca2+-sensing receptor in rat intestine Naibedya Chattopadhyay, Ivan Cheng, KIMBERLY V. ROGERS et al. · American Journal of Physiology-Gastrointestinal and Liver Physiology 1998 220
12 Efficacy and Safety of Human Parathyroid Hormone-(1–84) in Increasing Bone Mineral Density in Postmenopausal Osteoporosis Anthony B. Hodsman, David A. Hanley, Mark P. Ettinger et al. · The Journal of Clinical Endocrinology & Metabolism Open access Nov 2003 205
13 Heteropodatoxins: Peptides Isolated from Spider Venom that Block Kv4.2 Potassium Channels Michael C. Sanguinetti, JANICE H. JOHNSON, Lance G. Hammerland et al. · Molecular Pharmacology Mar 1997 197
14 Strategy for Identifying Repurposed Drugs for the Treatment of Cerebral Cavernous Malformation Christopher C. Gibson, Weiquan Zhu, Chadwick T. Davis et al. · Circulation Open access 9 Dec 2014 186
15 The calcium-sensing receptor regulates mammary gland parathyroid hormone–related protein production and calcium transport Joshua N. VanHouten, Pamela R. Dann, Grace McGeoch et al. · Journal of Clinical Investigation 14 Feb 2004 185
16 NPS R-568 halts or reverses osteitis fibrosa in uremic rats Michihito Wada, Hiromi Ishii, Yoshihiro FURUYA et al. · Kidney International Open access Feb 1998 151
17 Functional Consequences of Posttranslational Isomerization of Ser 46 in a Calcium Channel Toxin Steven D. Heck, Chester J. Siok, Karen J. Krapcho et al. · Science 11 Nov 1994 147
18 Regulation of murine fetal-placental calcium metabolism by the calcium-sensing receptor. Christopher S. Kovács, Chrystal L. Ho‐Pao, Joy L. Hunzelman et al. · Journal of Clinical Investigation Open access 15 Jun 1998 143
19 Defining a Noncarcinogenic Dose of Recombinant Human Parathyroid Hormone 1–84 in a 2-Year Study in Fischer 344 Rats Jacquelin Jolette, Clynn E. Wilker, Susan Y. Smith et al. · Toxicologic Pathology Dec 2006 142
20 β1 integrins and osteoclast function: Involvement in collagen recognition and bone resorption Miep Helfrich, Stephen A. Nesbitt, Päivi T. Lakkakorpi et al. · Bone Oct 1996 138
21 Calcimimetic NPS R-568 prevents parathyroid hyperplasia in rats with severe secondary hyperparathyroidism Michihito Wada, Nobuo Nagano, Yoshihiro FURUYA et al. · Kidney International Open access 2000 135
22 MPC-6827: A Small-Molecule Inhibitor of Microtubule Formation That Is Not a Substrate for Multidrug Resistance Pumps Shailaja Kasibhatla, Vijay R. Baichwal, Sui Xiong Cai et al. · Cancer Research 15 Jun 2007 130
23 Structure-Function Analysis of SH3 Domains: SH3 Binding Specificity Altered by Single Amino Acid Substitutions Zhigang Weng, Richard J. Rickles, Sibo Feng et al. · Molecular and Cellular Biology Open access Oct 1995 125
24 Amyloid-? proteins activate Ca2+-permeable channels through calcium-sensing receptors Chianping Ye, Chrystal L. Ho‐Pao, Marie Kanazirska et al. · Journal of Neuroscience Research Mar 1997 125
25 Expression of an extracellular calcium-sensing receptor in rat stomach Ivan Cheng, Imtiaz Qureshi, Naibedya Chattopadhyay et al. · Gastroenterology Open access 1999 124
26 Allosteric Activation of the Ca2+ Receptor Expressed in Xenopus laevis Oocytes by NPS 467 or NPS 568 Lance G. Hammerland, James E. Garrett, Benjamin C.P. Hung et al. · Molecular Pharmacology Jun 1998 123
27 Domains Determining Ligand Specificity for Ca2+ Receptors Lance G. Hammerland, Karen J. Krapcho, James E. Garrett et al. · Molecular Pharmacology Apr 1999 122
28 A pesticide and iPSC dopaminergic neuron screen identifies and classifies Parkinson-relevant pesticides Kimberly C. Paul, Richard C. Krolewski, Edinson Lucumi Moreno et al. · Nature Communications Open access 16 May 2023 117
29 NPS R-568: A Type II Calcimimetic Compound that Acts on Parathyroid Cell Calcium Receptor of Rats to Reduce Plasma Levels of Parathyroid Hormone and Calcium John Fox, Stacey H. Lowe, Barbara A. Petty et al. · Journal of Pharmacology and Experimental Therapeutics Aug 1999 113
30 Calcimimetic Compounds: a Direct Approach to Controlling Plasma Levels of Parathyroid Hormone in Hyperparathyroidism Edward F. Nemeth, John Fox · Trends in Endocrinology and Metabolism Review Mar 1999 106
31 The Venus Fly Trap Domain of the Extracellular Ca2+-sensing Receptor Is Required for l-Amino Acid Sensing Hee‐Chang Mun, Alison H. Franks, Emma L. Culverston et al. · Journal of Biological Chemistry Open access Sep 2004 103
32 Coupling of Calcium Receptors to Inositol Phosphate and Cyclic AMP Generation in Mammalian Cells and Xenopus laevis Oocytes and Immunodetection of Receptor Protein by Region-Specific Antipeptide Antisera Wenhan Chang, Stacy A. Pratt, Tsui‐Hua Chen et al. · Journal of Bone and Mineral Research Apr 1998 95
33 Activation of the Calcium Receptor by a Calcimimetic Compound Halts the Progression of Secondary Hyperparathyroidism in Uremic Rats JI CHIN, Scott C. Miller, Michihito Wada et al. · Journal of the American Society of Nephrology May 2000 95
34 Enhanced Sensitivity to the HER1/Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor Erlotinib Hydrochloride in Chemotherapy-Resistant Tumor Cell Lines Qun Dai, Yi‐He Ling, Marie Lia et al. · Clinical Cancer Research Open access 15 Feb 2005 91
35 Dietary Vitamin D and Its Metabolites Non-Genomically Stabilize the Endothelium Christopher C. Gibson, Chadwick T. Davis, Weiquan Zhu et al. · PLoS ONE Open access 15 Oct 2015 87
36 YY1 Facilitates the Association of Serum Response Factor with the c- fos Serum Response Element Sridaran Natesan, Michael Gilman · Molecular and Cellular Biology Open access Nov 1995 86
37 N-Linked Glycosylation of the Human Ca2+Receptor Is Essential for Its Expression at the Cell Surface Gaofeng Fan, Paul K. Goldsmith, Regina M. Collins et al. · Endocrinology May 1997 86
38 Agonists of the Ca2+-Sensing Receptor (CaR) Activate Nonselective Cation Channels in HEK293 Cells Stably Transfected with the Human CaR Chianping Ye, KIMBERLY V. ROGERS, Mei Bai et al. · Biochemical and Biophysical Research Communications Sep 1996 84
39 Genetic ancestry analysis on >93,000 individuals undergoing expanded carrier screening reveals limitations of ethnicity-based medical guidelines Kristjan Eerik Kaseniit, Imran S. Haque, James D. Goldberg et al. · Genetics in Medicine Open access 28 Jun 2020 82
40 Disparate effects of mild, moderate, and severe secondary hyperparathyroidism on cancellous and cortical bone in rats with chronic renal insufficiency Michael A. Miller, JI CHIN, Scott C. Miller et al. · Bone Sep 1998 82
41 Cloning and Characterization of a Calcium-Sensing Receptor from the Hypercalcemic New Zealand White Rabbit Reveals Unaltered Responsiveness to Extracellular Calcium Robert R. Butters, Naibedya Chattopadhyay, Palle Kjaerulff Nielsen et al. · Journal of Bone and Mineral Research Open access Apr 1997 82
42 Aurora‐A over‐expression in high‐grade PIN lesions and prostate cancer Holly McKlveen Buschhorn, Robert R. Klein, Susan M. Chambers et al. · The Prostate 7 Mar 2005 81
43 An orally active calcium-sensing receptor antagonist that transiently increases plasma concentrations of PTH and stimulates bone formation Sanjay Kumar et al. · Bone 27 Sep 2009 80
44 A Novel Compound ARN-3236 Inhibits Salt-Inducible Kinase 2 and Sensitizes Ovarian Cancer Cell Lines and Xenografts to Paclitaxel Jinhua Zhou, Albandri Alfraidi, Shu Zhang et al. · Clinical Cancer Research Open access 27 Sep 2016 78
45 Calcimimetic Compound NPS R-568 Stimulates Calcitonin Secretion But Selectively Targets Parathyroid Gland Ca2+ Receptor in Rats John Fox, Stacey H. Lowe, Rebecca L. Conklin et al. · Journal of Pharmacology and Experimental Therapeutics Aug 1999 77
46 Expression, Purification, and Biochemical Characterization of the Amino-terminal Extracellular Domain of the Human Calcium Receptor Paul K. Goldsmith, Gao-Feng Fan, Kausik Kumar Ray et al. · Journal of Biological Chemistry Open access Apr 1999 76
47 Daily intermittent decreases in serum levels of parathyroid hormone have an anabolic-like action on the bones of uremic rats with low-turnover bone and osteomalacia Hiromi Ishii, M. Wada, Y Furuya et al. · Bone Feb 2000 72
48 Clustering of Syk Is Sufficient To Induce Tyrosine Phosphorylation and Release of Allergic Mediators from Rat Basophilic Leukemia Cells Victor M. Rivera, Joan S. Brugge · Molecular and Cellular Biology Open access Mar 1995 70
49 Effects of daily treatment with parathyroid hormone 1–84 for 16 months on density, architecture and biomechanical properties of cortical bone in adult ovariectomized rhesus monkeys Jack J. Fox, Michael A. Miller, M. K. Newman et al. · Bone 15 May 2007 69
50 Characterization and cloning of insecticidal peptides from the primitive weaving spider Diguetia canities Karen J. Krapcho, Robert M. Kral, Bradford C. VanWagenen et al. · Insect Biochemistry and Molecular Biology Oct 1995 68

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.