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Most cited papers from Asan Medical Center

What are the most cited papers from Asan Medical Center?

The most cited paper from Asan Medical Center is "Trastuzumab in combination with chemotherapy versus chemotherapy alone for treatment of HER2-positive advanced gastric or gastro-oesophageal junction cancer (ToGA): a phase 3, open-label, randomised controlled trial" (Yung‐Jue Bang, Eric Van Cutsem, Andrea Feyereislova et al., 2010), with 7,405 citations. Next come "Comprehensive molecular characterization of gastric adenocarcinoma" (6,680) and "Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)" (6,023).

Showing 50 of 59 papers. Every paper with more than 1,192 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 Trastuzumab in combination with chemotherapy versus chemotherapy alone for treatment of HER2-positive advanced gastric or gastro-oesophageal junction cancer (ToGA): a phase 3, open-label, randomised controlled trial Yung‐Jue Bang, Eric Van Cutsem, Andrea Feyereislova et al. · The Lancet Open access Aug 2010 7,405
2 Comprehensive molecular characterization of gastric adenocarcinoma Adam Joel Bass et al. · Nature Open access258 authors 23 Jul 2014 6,680
3 Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) Daniel J. Klionsky et al. · Autophagy Open access2,467 authors 2 Jan 2016 6,023
4 Efficacy and safety of sorafenib in patients in the Asia-Pacific region with advanced hepatocellular carcinoma: a phase III randomised, double-blind, placebo-controlled trial Ann‐Lii Cheng et al. · The Lancet Oncology 18 Dec 2008 5,881
5 Detection of Circulating Tumor DNA in Early- and Late-Stage Human Malignancies Chetan Bettegowda et al. · Science Translational Medicine Open access 19 Feb 2014 5,211
6 Genetic effects on gene expression across human tissues François Aguet et al. · Nature Open access250 authors 10 Oct 2017 4,762
7 Efficacy and Safety of Nintedanib in Idiopathic Pulmonary Fibrosis Luca Richeldi et al. · New England Journal of Medicine Open access 18 May 2014 4,731
8 Nivolumab in patients with advanced hepatocellular carcinoma (CheckMate 040): an open-label, non-comparative, phase 1/2 dose escalation and expansion trial Anthony B. El-Khoueiry et al. · The Lancet Open access 20 Apr 2017 4,384
9 The repertoire of mutational signatures in human cancer Ludmil B. Alexandrov et al. · Nature Open access1,384 authors 5 Feb 2020 3,854
10 Pembrolizumab as Second-Line Therapy for Advanced Urothelial Carcinoma Joaquim Bellmunt, Ronald de Wit, David J. Vaughn et al. · New England Journal of Medicine Open access 17 Feb 2017 3,457
11 Pan-cancer analysis of whole genomes Lauri A. Aaltonen et al. · Nature Open access1,324 authors 5 Feb 2020 3,360
12 Pembrolizumab in Microsatellite-Instability–High Advanced Colorectal Cancer Thierry André et al. · New England Journal of Medicine Open access 2 Dec 2020 3,130
13 Enzalutamide in Metastatic Prostate Cancer before Chemotherapy Tomasz M. Beer et al. · New England Journal of Medicine Open access Jun 2014 3,076
14 Nivolumab plus Ipilimumab in Advanced Non–Small-Cell Lung Cancer Matthew David Hellmann et al. · New England Journal of Medicine Open access 28 Sep 2019 2,901
15 Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations Jimmy Z. Liu et al. · Nature Genetics Open access 20 Jul 2015 2,805
16 Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition) 1 Daniel J. Klionsky et al. · Autophagy Open access2,930 authors 2 Jan 2021 2,743
17 Trastuzumab Deruxtecan in Previously Treated HER2-Low Advanced Breast Cancer Shanu Modi et al. · New England Journal of Medicine Open access 5 Jun 2022 2,702
18 Asian-Pacific clinical practice guidelines on the management of hepatitis B: a 2015 update Shiv Kumar Sarin et al. · Hepatology International Open access 13 Nov 2015 2,603
19 Avelumab plus Axitinib versus Sunitinib for Advanced Renal-Cell Carcinoma Robert John Motzer et al. · New England Journal of Medicine Open access 16 Feb 2019 2,590
20 Pertuzumab plus Trastuzumab plus Docetaxel for Metastatic Breast Cancer José Baselga, Javier Cortés, Sung‐Bae Kim et al. · New England Journal of Medicine Open access 7 Dec 2011 2,559
21 Comprehensive genomic profiles of small cell lung cancer Julie George et al. · Nature Open access 10 Jul 2015 2,448
22 Landscape of somatic mutations in 560 breast cancer whole-genome sequences Serena Nik‐Zainal et al. · Nature Open access 29 Apr 2016 2,395
23 Cabozantinib in Patients with Advanced and Progressing Hepatocellular Carcinoma Ghassan K. Abou‐Alfa et al. · New England Journal of Medicine Open access 4 Jul 2018 2,386
24 Nivolumab in patients with advanced gastric or gastro-oesophageal junction cancer refractory to, or intolerant of, at least two previous chemotherapy regimens (ONO-4538-12, ATTRACTION-2): a randomised, double-blind, placebo-controlled, phase 3 trial Yoon‐Koo Kang et al. · The Lancet Open access 12 Oct 2017 2,317
25 Surviving Sepsis Campaign: guidelines on the management of critically ill adults with Coronavirus Disease 2019 (COVID-19) Waleed A. Alhazzani et al. · Intensive Care Medicine Open access 28 Mar 2020 2,204
26 Pertuzumab, Trastuzumab, and Docetaxel in HER2-Positive Metastatic Breast Cancer Sandra M. Swain, José Baselga, Sung‐Bae Kim et al. · New England Journal of Medicine Open access 18 Feb 2015 2,183
27 AZD9291 in EGFR Inhibitor–Resistant Non–Small-Cell Lung Cancer Pasi Antero Janne, James Chih‐Hsin Yang, Dong‐Wan Kim et al. · New England Journal of Medicine Open access 29 Apr 2015 2,135
28 Lenvatinib versus Placebo in Radioiodine-Refractory Thyroid Cancer Martin Jean Schlumberger, Makoto Tahara, Lori J. Wirth et al. · New England Journal of Medicine Open access 11 Feb 2015 2,109
29 Trastuzumab Deruxtecan in Previously Treated HER2-Positive Breast Cancer Shanu Modi et al. · New England Journal of Medicine Open access 11 Dec 2019 2,026
30 Adjuvant Capecitabine for Breast Cancer after Preoperative Chemotherapy Norikazu Masuda et al. · New England Journal of Medicine Open access 31 May 2017 1,947
31 Pembrolizumab As Second-Line Therapy in Patients With Advanced Hepatocellular Carcinoma in KEYNOTE-240: A Randomized, Double-Blind, Phase III Trial Richard S. Finn et al. · Journal of Clinical Oncology 2 Dec 2019 1,842
32 Osimertinib in Resected EGFR -Mutated Non–Small-Cell Lung Cancer Yi-Long Lung Cancer Wu et al. · New England Journal of Medicine Open access 19 Sep 2020 1,809
33 KRAS G12C Inhibition with Sotorasib in Advanced Solid Tumors David S. Hong et al. · New England Journal of Medicine Open access 20 Sep 2020 1,743
34 The Effectiveness and Risks of Bariatric Surgery Su‐Hsin Chang, Carolyn R. T. Stoll, Ji‐Hyun Song et al. · JAMA Surgery Open access 18 Dec 2013 1,688
35 Ramucirumab after sorafenib in patients with advanced hepatocellular carcinoma and increased α-fetoprotein concentrations (REACH-2): a randomised, double-blind, placebo-controlled, phase 3 trial Andrew Xiuxuan Zhu et al. · The Lancet Oncology 18 Jan 2019 1,680
36 Pembrolizumab plus chemotherapy versus chemotherapy alone for first-line treatment of advanced oesophageal cancer (KEYNOTE-590): a randomised, placebo-controlled, phase 3 study Jong‐Mu Sun et al. · The Lancet Open access Aug 2021 1,679
37 Sorafenib in radioactive iodine-refractory, locally advanced or metastatic differentiated thyroid cancer: a randomised, double-blind, phase 3 trial Marcia S. Brose, Christopher M. Nutting, Barbara Jarząb et al. · The Lancet Open access 23 Apr 2014 1,665
38 Hepatic steatosis index: A simple screening tool reflecting nonalcoholic fatty liver disease Jeong‐Hoon Lee, Donghee Kim, Hwa Jung Kim et al. · Digestive and Liver Disease 19 Sep 2009 1,664
39 Association analysis identifies 65 new breast cancer risk loci Kyriaki Michailidou et al. · Nature Open access362 authors 20 Oct 2017 1,602
40 Intensive care management of coronavirus disease 2019 (COVID-19): challenges and recommendations Jason Phua, Li Weng, Lowell Ling et al. · The Lancet Respiratory Medicine Open access 6 Apr 2020 1,580
41 Tremelimumab plus Durvalumab in Unresectable Hepatocellular Carcinoma Ghassan K. Abou‐Alfa et al. · NEJM Evidence Open access 6 Jun 2022 1,534
42 International Consensus Diagnostic Criteria for Autoimmune Pancreatitis Tooru Shimosegawa, Suresh T. Chari, Luca Frulloni et al. · Pancreas 16 Mar 2011 1,529
43 Encorafenib, Binimetinib, and Cetuximab in BRAF V600E–Mutated Colorectal Cancer Scott Kopetz et al. · New England Journal of Medicine Open access 30 Sep 2019 1,500
44 Diagnostic Performance of Noninvasive Fractional Flow Reserve Derived From Coronary Computed Tomography Angiography in Suspected Coronary Artery Disease Bjarne Linde Nørgaard, Jonathon A Leipsic, Sara Gaur et al. · Journal of the American College of Cardiology Open access 31 Jan 2014 1,498
45 Outcomes associated with drug-eluting and bare-metal stents: a collaborative network meta-analysis Christoph David Stettler et al. · The Lancet Sep 2007 1,432
46 Efficacy and safety of regorafenib for advanced gastrointestinal stromal tumours after failure of imatinib and sunitinib (GRID): an international, multicentre, randomised, placebo-controlled, phase 3 trial George D. Demetri et al. · The Lancet Open access 21 Nov 2012 1,428
47 Trastuzumab Deruxtecan in Previously Treated HER2-Positive Gastric Cancer Kohei Shitara, Yung‐Jue Bang, Satoru Iwasa et al. · New England Journal of Medicine Open access 29 May 2020 1,352
48 Pembrolizumab versus paclitaxel for previously treated, advanced gastric or gastro-oesophageal junction cancer (KEYNOTE-061): a randomised, open-label, controlled, phase 3 trial Kohei Shitara et al. · The Lancet Open access158 authors 4 Jun 2018 1,338
49 Deep Learning in Medical Imaging: General Overview June‐Goo Lee, Sanghoon Jun, Young-Won Cho et al. · Korean Journal of Radiology Open access 2017 1,298
50 Intertumoral Heterogeneity within Medulloblastoma Subgroups Florence M.G. Cavalli et al. · Cancer Cell Open access Jun 2017 1,290

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.