| 1 |
Global estimates of mortality associated with long-term exposure to outdoor fine particulate matter
Richard T. Burnett et al. · Proceedings of the National Academy of Sciences
Open access |
4 Sep 2018 |
2,561 |
| 2 |
Efficacy of HPV-based screening for prevention of invasive cervical cancer: follow-up of four European randomised controlled trials
Guglielmo Ronco, Joakim Dillner, K. Miriam Elfström et al. · The Lancet
Open access |
2 Nov 2013 |
1,845 |
| 3 |
Physical Frailty: ICFSR International Clinical Practice Guidelines for Identification and Management
Elsa Dent et al. · The journal of nutrition health & aging
Open access |
3 Oct 2019 |
1,087 |
| 4 |
New evidences on the altered gut microbiota in autism spectrum disorders
Francesco Strati, Duccio Cavalieri, Davide Albanese et al. · Microbiome
Open access |
21 Feb 2017 |
1,072 |
| 5 |
Prevalence and Clinical Manifestations of Primary Aldosteronism Encountered in Primary Care Practice
Silvia Monticone, Jacopo Burrello, Davide Tizzani et al. · Journal of the American College of Cardiology
Open access |
Apr 2017 |
884 |
| 6 |
Once-Only Sigmoidoscopy in Colorectal Cancer Screening: Follow-up Findings of the Italian Randomized Controlled Trial--SCORE
Nereo Segnan et al. · JNCI Journal of the National Cancer Institute
|
18 Aug 2011 |
626 |
| 7 |
Trastuzumab containing regimens for early breast cancer
Lorenzo Moja, Ludovica Tagliabue, Sara Balduzzi et al. · Cochrane Database of Systematic Reviews
Open access |
12 Apr 2012 |
612 |
| 8 |
Truncating FLNC Mutations Are Associated With High-Risk Dilated and Arrhythmogenic Cardiomyopathies
Martín Ortiz-Genga et al. · Journal of the American College of Cardiology
Open access |
28 Nov 2016 |
491 |
| 9 |
European position paper on the management of patients with patent foramen ovale. General approach and left circulation thromboembolism
Christian Pristipino et al. · European Heart Journal
Open access |
28 Sep 2018 |
445 |
| 10 |
Estimation of daily PM10 and PM2.5 concentrations in Italy, 2013–2015, using a spatiotemporal land-use random-forest model
Massimo Stafoggia, Tom Bellander, Simone Bucci et al. · Environment International
Open access |
14 Jan 2019 |
419 |
| 11 |
Understanding the Complex of Suicide in Depression: from Research to Clinics
Laura Orsolini, Roberto Latini, Maurizio Pompili et al. · Psychiatry Investigation
Open access |
22 Mar 2020 |
411 |
| 12 |
Autologous haematopoietic stem-cell transplantation versus bortezomib–melphalan–prednisone, with or without bortezomib–lenalidomide–dexamethasone consolidation therapy, and lenalidomide maintenance for newly diagnosed multiple myeloma (EMN02/HO95): a multicentre, randomised, open-label, phase 3 study
Michèle Cavo et al. · The Lancet Haematology
Open access |
30 Apr 2020 |
387 |
| 13 |
Spatial PM2.5, NO2, O3 and BC models for Western Europe – Evaluation of spatiotemporal stability
Kees de Hoogh et al. · Environment International
Open access |
31 Jul 2018 |
383 |
| 14 |
Dosimetric characterization and use of GAFCHROMIC EBT3 film for IMRT dose verification
Valeria Casanova Borca, Massimo Pasquino, Giuliana Russo et al. · Journal of Applied Clinical Medical Physics
Open access |
Mar 2013 |
382 |
| 15 |
Morphological Deficits in Children With Specific Language Impairment: The Status of Features in the Underlying Grammar
Laurence B. Leonard, María Cristina Caselli, Umberta Bortolini et al. · Language Acquisition
|
Apr 1992 |
367 |
| 16 |
Long-term exposure to low ambient air pollution concentrations and mortality among 28 million people: results from seven large European cohorts within the ELAPSE project
Massimo Stafoggia et al. · The Lancet Planetary Health
Open access |
2022 |
362 |
| 17 |
A comparison of linear regression, regularization, and machine learning algorithms to develop Europe-wide spatial models of fine particles and nitrogen dioxide
Jie Chen et al. · Environment International
Open access |
20 Jun 2019 |
343 |
| 18 |
Estimating the Exposure–Response Relationships between Particulate Matter and Mortality within the APHEA Multicity Project
Evangelia Samoli, Antonis Analitis, Giota Touloumi et al. · Environmental Health Perspectives
Open access |
21 Oct 2004 |
337 |
| 19 |
Challenges in the management of chronic wound infections
Marco Falcone, Barbara De Angelis, Federico Pea et al. · Journal of Global Antimicrobial Resistance
Open access |
15 Jun 2021 |
333 |
| 20 |
Cerebral palsy and intrauterine growth in single births: European collaborative study
S N Jarvis, Svetlana V. Glinianaia, Maria-Giulia Torrioli et al. · The Lancet
|
Oct 2003 |
330 |
| 21 |
Air Pollution and Respiratory Infections during Early Childhood: An Analysis of 10 European Birth Cohorts within the ESCAPE Project
Elaina MacIntyre et al. · Environmental Health Perspectives
Open access |
22 Oct 2013 |
314 |
| 22 |
Alemtuzumab (Campath-1H) and CHOP chemotherapy as first-line treatment of peripheral T-cell lymphoma: results of a GITIL (Gruppo Italiano Terapie Innovative nei Linfomi) prospective multicenter trial
Andrea Gallamini, Francesco F. Zaja, Caterina Patti et al. · Blood
Open access |
20 Jun 2007 |
310 |
| 23 |
Quantifying the health impacts of ambient air pollutants: recommendations of a WHO/Europe project
Marie-Ève Héroux, H Ross Anderson, Richard Atkinson et al. · International Journal of Public Health
Open access |
29 May 2015 |
302 |
| 24 |
Effects on the incidence of cardiovascular events of the addition of pioglitazone versus sulfonylureas in patients with type 2 diabetes inadequately controlled with metformin (TOSCA.IT): a randomised, multicentre trial
Olga Vaccaro et al. · The Lancet Diabetes & Endocrinology
439 authors |
13 Sep 2017 |
297 |
| 25 |
Very-low-calorie ketogenic diet (VLCKD) in the management of metabolic diseases: systematic review and consensus statement from the Italian Society of Endocrinology (SIE)
Massimiliano Caprio et al. · Journal of Endocrinological Investigation
Review |
20 May 2019 |
296 |
| 26 |
The Impact of Digital Patient Portals on Health Outcomes, System Efficiency, and Patient Attitudes: Updated Systematic Literature Review
Elettra Carini, Leonardo Villani, Angelo Maria Pezzullo et al. · Journal of Medical Internet Research
ReviewOpen access |
8 Sep 2021 |
288 |
| 27 |
Long term exposure to low level air pollution and mortality in eight European cohorts within the ELAPSE project: pooled analysis
Maciej Strak et al. · BMJ
Open access |
Sep 2021 |
287 |
| 28 |
Mucosal Healing Predicts Late Outcomes After the First Course of Corticosteroids for Newly Diagnosed Ulcerative Colitis
Sandro Ardizzone, A. Cassinotti, Piergiorgio Duca et al. · Clinical Gastroenterology and Hepatology
|
2011 |
287 |
| 29 |
Overweight and obesity in infants and pre‐school children in the European Union: a review of existing data
Adriano Cattaneo, Lorenzo Monasta, Emmanuel Stamatakis et al. · Obesity Reviews
|
10 Jul 2009 |
286 |
| 30 |
Asthma control in Europe: A real-world evaluation based on an international population-based study
Lucia Cazzoletti, Alessandro Marcon, Christer Janson et al. · Journal of Allergy and Clinical Immunology
|
Dec 2007 |
279 |
| 31 |
Local opinion leaders: effects on professional practice and healthcare outcomes
Gerd Flodgren, Mary Ann O’Brien, Elena Parmelli et al. · Cochrane Database of Systematic Reviews
Open access |
24 Jun 2019 |
276 |
| 32 |
Pre-Frailty and Risk of Cardiovascular Disease in Elderly Men and Women
Giuseppe Sergi, Nicola Veronese, Luigi Fontana et al. · Journal of the American College of Cardiology
Open access |
Mar 2015 |
276 |
| 33 |
Detection of Multiple Noroviruses Associated with an International Gastroenteritis Outbreak Linked to Oyster Consumption
Françoise S. Le Guyader, Fabienne Bon, Dario De Medici et al. · Journal of Clinical Microbiology
Open access |
Nov 2006 |
273 |
| 34 |
Excess mortality attributed to heat and cold: a health impact assessment study in 854 cities in Europe
Pierre Masselot et al. · The Lancet Planetary Health
Open access |
16 Mar 2023 |
270 |
| 35 |
Long-term exposure to low-level ambient air pollution and incidence of stroke and coronary heart disease: a pooled analysis of six European cohorts within the ELAPSE project
Kathrin Wolf et al. · The Lancet Planetary Health
Open access |
Sep 2021 |
260 |
| 36 |
Early symptom progression rate is related to ALS outcome
Adriano Chiò, Gabriele Mora, Maurizio Angelo Leone et al. · Neurology
|
9 Jul 2002 |
258 |
| 37 |
Telomere damage induced by the G-quadruplex ligand RHPS4 has an antitumor effect
Erica Salvati, Carlo Leonetti, Angela Rizzo et al. · Journal of Clinical Investigation
Open access |
12 Oct 2007 |
257 |
| 38 |
Methodological issues regarding confounding and exposure misclassification in epidemiological studies of occupational exposures
Aaron Blair, Patricia Ann Stewart, Jay H. Lubin et al. · American Journal of Industrial Medicine
|
9 Nov 2006 |
254 |
| 39 |
Carfilzomib with cyclophosphamide and dexamethasone or lenalidomide and dexamethasone plus autologous transplantation or carfilzomib plus lenalidomide and dexamethasone, followed by maintenance with carfilzomib plus lenalidomide or lenalidomide alone for patients with newly diagnosed multiple myeloma (FORTE): a randomised, open-label, phase 2 trial
Francesca Gay et al. · The Lancet Oncology
|
11 Nov 2021 |
251 |
| 40 |
Effects of Low Blood Pressure in Cognitively Impaired Elderly Patients Treated With Antihypertensive Drugs
Enrico Mossello, Mariachiara Pieraccioli, Nicola Nesti et al. · JAMA Internal Medicine
Open access |
2 Mar 2015 |
249 |
| 41 |
Sitagliptin Treatment at the Time of Hospitalization Was Associated With Reduced Mortality in Patients With Type 2 Diabetes and COVID-19: A Multicenter, Case-Control, Retrospective, Observational Study
Sebastiano Bruno Solerte et al. · Diabetes Care
Open access |
29 Sep 2020 |
248 |
| 42 |
Short term association between ozone and mortality: global two stage time series study in 406 locations in 20 countries
Ana M. Vicedo‐Cabrera et al. · BMJ
Open access |
10 Feb 2020 |
248 |
| 43 |
Colonic diverticular disease
Antonio Tursi, Carmelo Scarpignato, Lisa L. Strate et al. · Nature Reviews Disease Primers
ReviewOpen access |
26 Mar 2020 |
246 |
| 44 |
Excess all-cause mortality during the COVID-19 pandemic in Europe – preliminary pooled estimates from the EuroMOMO network, March to April 2020
Lasse Skafte Vestergaard et al. · Eurosurveillance
Open access |
2 Jul 2020 |
239 |
| 45 |
Chemotherapy-induced neutropenia and treatment efficacy in advanced non-small-cell lung cancer: a pooled analysis of three randomised trials
Massimo Di Maïo, Cesare Gridelli, Ciro Gallo et al. · The Lancet Oncology
|
3 Aug 2005 |
237 |
| 46 |
Vaccines for preventing influenza in healthy adults
Vittorio Demicheli, Tom Jefferson, Eliana Ferroni et al. · Cochrane Database of Systematic Reviews
Open access |
Feb 2018 |
234 |
| 47 |
Remote Ischemic Post-Conditioning of the Lower Limb During Primary Percutaneous Coronary Intervention Safely Reduces Enzymatic Infarct Size in Anterior Myocardial Infarction
Gabriele Crimi, Silvia Pica, Claudia Raineri et al. · JACC: Cardiovascular Interventions
Open access |
Oct 2013 |
234 |
| 48 |
Rotator Cuff Calcific Tendonitis: Short-term and 10-year Outcomes after Two-Needle US-guided Percutaneous Treatment— Nonrandomized Controlled Trial
Giovanni Serafini, Luca Maria Sconfienza, Francesca Lacelli et al. · Radiology
|
26 Jun 2009 |
233 |
| 49 |
Statistical Approaches to Address Multi-Pollutant Mixtures and Multiple Exposures: the State of the Science
Massimo Stafoggia, Susanne Breitner, Regina Hampel et al. · Current Environmental Health Reports
|
7 Oct 2017 |
220 |
| 50 |
Prognostic factors of asthma severity: A 9-year international prospective cohort study
Roberto de Marco, Alessandro Marcon, Deborah Jarvis et al. · Journal of Allergy and Clinical Immunology
|
Jun 2006 |
216 |