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Institution · BBB Therapeutics (Netherlands)

Most cited papers from BBB Therapeutics (Netherlands)

BBB Therapeutics (Netherlands)

What are the most cited papers from BBB Therapeutics (Netherlands)?

The most cited paper from BBB Therapeutics (Netherlands) is "Checkpoint blockade cancer immunotherapy targets tumour-specific mutant antigens" (Matthew M. Gubin et al., 2014), with 2,015 citations. Next come "Combination of cGMP analogue and drug delivery system provides functional protection in hereditary retinal degeneration" (116) and "Glutathione conjugation dose-dependently increases brain-specific liposomal drug delivery in vitro and in vivo" (91).

Showing 20 of 20 papers. Every paper is listed.

Most cited papers, sortable by citations and release date
#Paper
1 Checkpoint blockade cancer immunotherapy targets tumour-specific mutant antigens Matthew M. Gubin et al. · Nature Open access 25 Nov 2014 2,015
2 Combination of cGMP analogue and drug delivery system provides functional protection in hereditary retinal degeneration Eleonora Vighi, Dragana Trifunović, Patricia Veiga‐Crespo et al. · Proceedings of the National Academy of Sciences Open access 12 Mar 2018 116
3 Glutathione conjugation dose-dependently increases brain-specific liposomal drug delivery in vitro and in vivo David Maussang, Jaap Rip, Joan van Kregten et al. · Drug Discovery Today Technologies Jun 2016 91
4 Drug delivery to retinal photoreceptors Erico Himawan, Per A.R. Ekström, Matěj Buzgo et al. · Drug Discovery Today Open access 12 Mar 2019 63
5 Targeted brain delivery of methotrexate by glutathione PEGylated liposomes: How can the formulation make a difference? Yang Hu, Pieter Jaap Gaillard, Elizabeth C. M. de Lange et al. · European Journal of Pharmaceutics and Biopharmaceutics Open access 2 Apr 2019 52
6 Patient-reported adverse effects of high-dose intravenous methylprednisolone treatment: a prospective web-based multi-center study in multiple sclerosis patients with a relapse Peter Joseph Jongen, I. Stavrakaki, Bernard Voet et al. · Journal of Neurology Open access 7 Jun 2016 48
7 The Impact of Liposomal Formulations on the Release and Brain Delivery of Methotrexate: An In Vivo Microdialysis Study Yang Hu, Jaap Rip, Pieter Jaap Gaillard et al. · Journal of Pharmaceutical Sciences Open access 18 Mar 2017 44
8 Preclinical evaluation of convection-enhanced delivery of liposomal doxorubicin to treat pediatric diffuse intrinsic pontine glioma and thalamic high-grade glioma Andreas Sewing, Tonny Lagerweij, Dannis G van Vuurden et al. · Journal of Neurosurgery Pediatrics Open access 17 Feb 2017 34
9 Glutathione‐PEGylated liposomal methylprednisolone in comparison to free methylprednisolone: slow release characteristics and prolonged lymphocyte depression in a first‐in‐human study Kawita M. S. Kanhai, Rob G. J. A. Zuiker, I. Stavrakaki et al. · British Journal of Clinical Pharmacology Open access 31 Jan 2018 31
10 In Vivo Quantitative Understanding of PEGylated Liposome’s Influence on Brain Delivery of Diphenhydramine Yang Hu, Pieter Jaap Gaillard, Jaap Rip et al. · Molecular Pharmaceutics Open access 30 Oct 2018 26
11 Imaged-guided focused ultrasound in combination with various formulations of doxorubicin for the treatment of diffuse intrinsic pontine glioma Rianne Haumann, John I. Bianco, Piotr Waranecki et al. · Translational Medicine Communications Open access 18 Apr 2022 16
12 Current research into brain barriers and the delivery of therapeutics for neurological diseases: a report on CNS barrier congress London, UK, 2017 John R. Greenwood, Margareta Hammarlund‐Udenaes, Hazel C. Jones et al. · Fluids and Barriers of the CNS Open access 2 Nov 2017 12
13 Polymeric nanoparticle-based mRNA vaccine is protective against influenza virus infection in ferrets Gijs Hardenberg, Chantal Brouwer, Rachelle van Gemerden et al. · Molecular Therapy — Nucleic Acids Open access 19 Feb 2024 10
14 BBB crossing assessment and BBB crossing technologies in CNS Drug Discovery Pieter Jaap Gaillard · Drug Discovery Today Technologies Jun 2016 9
15 Improved tendon repair with optimized chemically modified mRNAs: Combined delivery of Pdgf-BB and IL-1Ra using injectable nanoparticles Bettina Faustini, Thomas Lettner, Andrea Wagner et al. · Acta Biomaterialia Open access 10 Feb 2025 6
16 Treatment with penicillin G and hydrocortisone reduces ALS-associated symptoms: a case series of three patients Bert Tuk, Harmen Jousma, Pieter Jaap Gaillard · F1000Research Open access 3 Apr 2017 6
17 Blood-to-Brain Drug Delivery Using Nanocarriers Yang Hu, Pieter Jaap Gaillard, Jaap Rip et al. · AAPS advances in the pharmaceutical sciences series Book chapter 2022 2
18 Double-blind, placebo and active comparator-controlled study in Healthy Males followed by an open-label study in Healty Males and Females, to asses the safety, Pharmacokinetics and –dynamics of 2B3-201 Kawita M. S. Kanhai, Rob G. J. A. Zuiker, Werner Gladdines et al. · Clinical Therapeutics Open access 24 Jun 2015 2
19 Recent Advances and Trends in the Brain Delivery of Small Molecule Based Cancer Therapies Werner Gladdines, Corine C. Visser, Marco de Boer et al. · Elsevier eBooks Book chapter 2015 0
20 Astrocyte-derived retinoic acid: a novel regulator of blood–brain barrier function during neuroinflammation in multiple sclerosis Mark Ronald Mizee, Philip G. Nijland, Susanne van der Pol et al. · Journal of Neuroimmunology Oct 2014 0

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.