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Most cited papers from Bio-Prodict (Netherlands)

What are the most cited papers from Bio-Prodict (Netherlands)?

The most cited paper from Bio-Prodict (Netherlands) is "Protein structure analysis of mutations causing inheritable diseases. An e-Science approach with life scientist friendly interfaces" (Hanka Venselaar, Tim AH te Beek, Remko K. P. Kuipers et al., 2010), with 1,205 citations. Next come "GPCRdb: an information system for G protein-coupled receptors" (1,098) and "A series of PDB-related databanks for everyday needs" (1,026).

Showing 50 of 50 papers. Every paper is listed.

Most cited papers, sortable by citations and release date
#Paper
1 Protein structure analysis of mutations causing inheritable diseases. An e-Science approach with life scientist friendly interfaces Hanka Venselaar, Tim AH te Beek, Remko K. P. Kuipers et al. · BMC Bioinformatics Open access 8 Nov 2010 1,205
2 GPCRdb: an information system for G protein-coupled receptors Vignir Ísberg, Stefan Mordalski, Christian Munk et al. · Nucleic Acids Research Open access 17 Nov 2015 1,098
3 A series of PDB-related databanks for everyday needs Wouter G. Touw, Coos A. B. Baakman, Jon E. Black et al. · Nucleic Acids Research Open access 28 Oct 2014 1,026
4 Bioinformatic analysis of a PLP-dependent enzyme superfamily suitable for biocatalytic applications Fabian Steffen‐Munsberg, Clare F. Vickers, Hannes Kohls et al. · Biotechnology Advances 7 Jan 2015 236
5 3DM: Systematic analysis of heterogeneous superfamily data to discover protein functionalities Remko K. P. Kuipers, Henk-Jan Joosten, Willem J. H. van Berkel et al. · Proteins Structure Function and Bioinformatics Open access 2010 149
6 The α/β‐Hydrolase Fold 3DM Database (ABHDB) as a Tool for Protein Engineering Robert Kourist, Helge Jochens, Sebastian Bartsch et al. · ChemBioChem Open access 6 Jul 2010 145
7 nanoDSF as screening tool for enzyme libraries and biotechnology development Anders O. Magnusson, Anna Szekrényi, Henk‐Jan Joosten et al. · FEBS Journal Open access 10 Nov 2018 143
8 Functional analysis of genetic variants in the high-risk breast cancer susceptibility gene PALB2 Rick A.C.M. Boonen, Amélie Rodrigue, Chantal Stoepker et al. · Nature Communications Open access 22 Nov 2019 65
9 Increasing the thermostability of sucrose phosphorylase by a combination of sequence- and structure-based mutagenesis An Cerdobbel, Karel De Winter, Dirk Aerts et al. · Protein Engineering Design and Selection Open access 6 Sep 2011 60
10 Breast cancer risks associated with missense variants in breast cancer susceptibility genes Leila Dorling et al. · Genome Medicine Open access109 authors 18 May 2022 59
11 Functional Analysis Identifies Damaging CHEK2 Missense Variants Associated with Increased Cancer Risk Rick A.C.M. Boonen, Wouter W. Wiegant, Nandi Celosse et al. · Cancer Research Open access 13 Dec 2021 57
12 Switch in Cofactor Specificity of a Baeyer–Villiger Monooxygenase Andy Beier, Sven Bordewick, Maika Genz et al. · ChemBioChem 13 Oct 2016 56
13 Drug design for ever, from hype to hope Gavin M. Seddon, Valère Lounnas, Ross McGuire et al. · Journal of Computer-Aided Molecular Design Open access 2012 56
14 Engineering the Amine Transaminase from Vibrio fluvialis towards Branched‐Chain Substrates Maika Genz, Okke Melse, Sandy Schmidt et al. · ChemCatChem 22 Aug 2016 55
15 A structural classification of carbohydrate epimerases: From mechanistic insights to practical applications Stevie Van Overtveldt, Tom Verhaeghe, Henk‐Jan Joosten et al. · Biotechnology Advances 25 Oct 2015 55
16 Two Subtle Amino Acid Changes in a Transaminase Substantially Enhance or Invert Enantiopreference in Cascade Syntheses Lilly Skalden, Christin Peters, Jonathan Dickerhoff et al. · ChemBioChem 20 Mar 2015 54
17 Complex phenotypes associated with STIM1 mutations in both coiled coil and EF-hand domains Elizabeth A. Harris, U. Burki, Chiara Marini‐Bettolo et al. · Neuromuscular Disorders 4 May 2017 49
18 Complete Switch of Reaction Specificity of an Aldolase by Directed Evolution In Vitro: Synthesis of Generic Aliphatic Aldol Products Sebastian Junker, Raquel Roldán, Henk‐Jan Joosten et al. · Angewandte Chemie International Edition Open access 8 Jun 2018 42
19 Enzyme discovery beyond homology: a unique hydroxynitrile lyase in the Bet v1 superfamily Elisa Lanfranchi, Tea Pavkov‐Keller, Eva-Maria Koehler et al. · Scientific Reports Open access 3 May 2017 37
20 Alteration of the Donor/Acceptor Spectrum of the (S)-Amine Transaminase from Vibrio fluvialis Maika Genz, Clare F. Vickers, Tom van den Bergh et al. · International Journal of Molecular Sciences Open access 11 Nov 2015 37
21 Digenic inheritance involving a muscle-specific protein kinase and the giant titin protein causes a skeletal muscle myopathy Ana Töpf et al. · Nature Genetics Open access Mar 2024 36
22 Consensus engineering of sucrose phosphorylase: The outcome reflects the sequence input Dirk Aerts, Tom Verhaeghe, Henk‐Jan Joosten et al. · Biotechnology and Bioengineering 24 Apr 2013 35
23 Recessive variants of MuSK are associated with late onset CMS and predominant limb girdle weakness David J Owen et al. · American Journal of Medical Genetics Part A 28 Apr 2018 34
24 A quantitative indicator diagram for lytic polysaccharide monooxygenases reveals the role of aromatic surface residues in HjLPMO9A regioselectivity Barbara Danneels, Magali Tanghe, Henk‐Jan Joosten et al. · PLoS ONE Open access 31 May 2017 33
25 Engineering Thermostability in Artificial Metalloenzymes to Increase Catalytic Activity Megan V. Doble, Lorenz Obrecht, Henk‐Jan Joosten et al. · ACS Catalysis Open access 8 Mar 2021 32
26 Going to extremes – a metagenomic journey into the dark matter of life Arnthór Aevarsson et al. · FEMS Microbiology Letters Open access Jun 2021 30
27 Structure-function relationships in NDP-sugar active SDR enzymes: Fingerprints for functional annotation and enzyme engineering Matthieu Da Costa, Ophelia Gevaert, Stevie Van Overtveldt et al. · Biotechnology Advances Open access 9 Feb 2021 30
28 Simultaneous Use of in Silico Design and a Correlated Mutation Network as a Tool To Efficiently Guide Enzyme Engineering Alberto Nobili, Yifeng Tao, Ioannis V. Pavlidis et al. · ChemBioChem 25 Feb 2015 29
29 Novel tools for extraction and validation of disease-related mutations applied to fabry disease Remko K. P. Kuipers, Tom van den Bergh, Henk‐Jan Joosten et al. · Human Mutation Open access 13 Jul 2010 22
30 Understanding structure-guided variant effect predictions using 3D convolutional neural networks Gayatri Ramakrishnan, Coos A. B. Baakman, Stephan Heijl et al. · Frontiers in Molecular Biosciences Open access 5 Jul 2023 17
31 Distant Non-Obvious Mutations Influence the Activity of a Hyperthermophilic Pyrococcus furiosus Phosphoglucose Isomerase Kalyanasundaram Subramanian, Karolina Mitusińska, John Raedts et al. · Biomolecules Open access 31 May 2019 16
32 NewProt – a protein engineering portal Andreas Schwarte, Maika Genz, Lilly Skalden et al. · Protein Engineering Design and Selection 13 Apr 2017 13
33 CorNet: Assigning function to networks of co-evolving residues by automated literature mining Tom van den Bergh, Giorgio E. Tamò, Alberto Nobili et al. · PLoS ONE Open access 18 May 2017 12
34 Navigating the Sequence-Function Landscape: AI-Driven Discovery of Unseen and Synergistic Mutations in an Amine Transaminase Konstantin F. G. Weigmann, Stephan Heijl, Bas Vroling et al. · ACS Catalysis Open access 17 Aug 2025 10
35 Determinants of the Nucleotide Specificity in the Carbohydrate Epimerase Family 1 Stevie Van Overtveldt, Matthieu Da Costa, Ophelia Gevaert et al. · Biotechnology Journal 6 Aug 2020 10
36 CPR-C4 is a highly conserved novel protease from the Candidate Phyla Radiation with remote structural homology to human vasohibins Katy A S Cornish, Joanna Lange, Arnthór Aevarsson et al. · Journal of Biological Chemistry Open access 8 Apr 2022 9
37 Facilities that make the PDB data collection more powerful Joanna Lange, Coos A. B. Baakman, Arthur M. A. Pistorius et al. · Protein Science Open access 14 Nov 2019 9
38 Beyond rational—biosensor-guided isolation of 100 independently evolved bacterial strain variants and comparative analysis of their genomes Philipp T. Baumann, Michael Dal Molin, Hannah Aring et al. · BMC Biology Open access 4 Sep 2023 7
39 AmiP from hyperthermophilic Thermus parvatiensis prophage is a thermoactive and ultrathermostable peptidoglycan lytic amidase Andrius Jasilionis, Magdalena Płotka, Lei Wang et al. · Protein Science Open access Feb 2023 6
40 Mind the gap: preventing circularity in missense variant prediction Stephan Heijl, Bas Vroling, Tom van den Bergh et al. · bioRxiv (Cold Spring Harbor Laboratory) PreprintOpen access 7 May 2020 6
41 Bioinformatic analysis of fold-type III PLP-dependent enzymes discovers multimeric racemases Anders M. Knight, Alberto Nobili, Tom van den Bergh et al. · Applied Microbiology and Biotechnology 27 Oct 2016 6
42 The Conversion of UDP‐Glc to UDP‐Man: In Silico and Biochemical Exploration To Improve the Catalytic Efficiency of CDP‐Tyvelose C2‐Epimerases Ulrike Vogel, Matthieu Da Costa, Carlos Alvarez Quispe et al. · ChemBioChem Open access 20 Sep 2023 4
43 The future of HOPE: what can and cannot be predicted about the molecular effects of a disease causing point mutation in a protein? Francesca Camilli, Annika Borrmann, Shima Gholizadeh et al. · EMBnet journal Open access 18 May 2011 4
44 The Future of Protein Secondary Structure Prediction Was Invented by Oleg Ptitsyn Daniel T. Rademaker, Jarek M. van Dijk, Willem Titulaer et al. · Biomolecules Open access 16 Jun 2020 3
45 #TAIA2012 Fernando Díaz, Susan Dumais, Kira Radinsky et al. · ACM SIGIR Forum 21 Dec 2012 1
46 Digenic inheritance as a causative mechanism of skeletal myopathy Ana Töpf et al. · Journal of the Neurological Sciences Dec 2025 0
47 Site-saturation functional screens identify PALB2 missense variants associated with increased breast cancer risk Rick A.C.M. Boonen et al. · Nature Communications Open access 19 Jan 2026 0
48 Interpretable and Physics-Supported Machine Learning Model for Sound Transmission Loss Analysis Barbara Zaparoli Cunha, Mohamed Najib Ichchou, Christophe Droz et al. · HAL (Le Centre pour la Communication Scientifique Directe) Conference paperOpen access 15 Sep 2022 0
49 Fahrzeugkomponenten in Echtzeit überwachen Stéphane Foulard, Stephan Rinderknecht, Rafael Fietzek · atp magazin 23 Jun 2017 0
50 Massive protein superfamily data integration applied to smart library design Henk‐Jan Joosten · New Biotechnology Jul 2014 0

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.