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Most cited papers from Biobyte Solutions (Germany)

What are the most cited papers from Biobyte Solutions (Germany)?

The most cited paper from Biobyte Solutions (Germany) is "Interactive Tree Of Life (iTOL) v5: an online tool for phylogenetic tree display and annotation" (Ivica Letunić, Peer Bork, 2021), with 12,232 citations. Next come "Interactive Tree Of Life (iTOL) v4: recent updates and new developments" (6,592) and "Interactive tree of life (iTOL) v3: an online tool for the display and annotation of phylogenetic and other trees" (5,530).

Showing 50 of 59 papers. Every paper with more than 48 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 Interactive Tree Of Life (iTOL) v5: an online tool for phylogenetic tree display and annotation Ivica Letunić, Peer Bork · Nucleic Acids Research Open access 12 Apr 2021 12,232
2 Interactive Tree Of Life (iTOL) v4: recent updates and new developments Ivica Letunić, Peer Bork · Nucleic Acids Research Open access 25 Mar 2019 6,592
3 Interactive tree of life (iTOL) v3: an online tool for the display and annotation of phylogenetic and other trees Ivica Letunić, Peer Bork · Nucleic Acids Research Open access 19 Apr 2016 5,530
4 eggNOG 5.0: a hierarchical, functionally and phylogenetically annotated orthology resource based on 5090 organisms and 2502 viruses Jaime Huerta‐Cepas, Damian Szklarczyk, Davide Heller et al. · Nucleic Acids Research Open access 26 Oct 2018 5,477
5 eggNOG-mapper v2: Functional Annotation, Orthology Assignments, and Domain Prediction at the Metagenomic Scale Carlos P. Cantalapiedra, Ana Hernández-Plaza, Ivica Letunić et al. · Molecular Biology and Evolution Open access 30 Sep 2021 5,074
6 Interactive Tree of Life (iTOL) v6: recent updates to the phylogenetic tree display and annotation tool Ivica Letunić, Peer Bork · Nucleic Acids Research Open access 2 Apr 2024 4,591
7 The repertoire of mutational signatures in human cancer Ludmil B. Alexandrov et al. · Nature Open access1,384 authors 5 Feb 2020 3,854
8 Pan-cancer analysis of whole genomes Lauri A. Aaltonen et al. · Nature Open access1,324 authors 5 Feb 2020 3,360
9 InterPro in 2022 Typhaine Paysan‐Lafosse et al. · Nucleic Acids Research Open access 9 Nov 2022 2,650
10 The InterPro protein families and domains database: 20 years on Matthias Blum et al. · Nucleic Acids Research Open access 23 Oct 2020 2,459
11 SMART: recent updates, new developments and status in 2020 Ivica Letunić, Supriya Khedkar, Peer Bork · Nucleic Acids Research Open access 6 Oct 2020 2,404
12 20 years of the SMART protein domain annotation resource Ivica Letunić, Peer Bork · Nucleic Acids Research Open access 29 Sep 2017 2,245
13 SMART: recent updates, new developments and status in 2015 Ivica Letunić, Tobias Doerks, Peer Bork · Nucleic Acids Research Open access 9 Oct 2014 1,834
14 InterPro in 2017—beyond protein family and domain annotations ROBERT FINN et al. · Nucleic Acids Research Open access 27 Oct 2016 1,598
15 InterPro in 2019: improving coverage, classification and access to protein sequence annotations Alex Mitchell et al. · Nucleic Acids Research Open access 22 Oct 2018 1,557
16 The SIDER database of drugs and side effects Michael Kuhn, Ivica Letunić, Lars Juhl Jensen et al. · Nucleic Acids Research Open access 19 Oct 2015 1,514
17 The evolutionary history of 2,658 cancers Moritz Gerstung et al. · Nature Open access1,441 authors 5 Feb 2020 1,149
18 InterPro: the protein sequence classification resource in 2025 Matthias Blum et al. · Nucleic Acids Research Open access 23 Oct 2024 1,084
19 Patterns of somatic structural variation in human cancer genomes Yilong Li et al. · Nature Open access1,411 authors 5 Feb 2020 1,005
20 Comprehensive analysis of chromothripsis in 2,658 human cancers using whole-genome sequencing Isidro Cortés-Ciriano et al. · Nature Genetics Open access1,407 authors 5 Feb 2020 793
21 Analyses of non-coding somatic drivers in 2,658 cancer whole genomes Esther Rheinbay et al. · Nature Open access1,621 authors 5 Feb 2020 674
22 Statin therapy is associated with lower prevalence of gut microbiota dysbiosis Sara Vieira‐Silva et al. · Nature Open access108 authors 6 May 2020 534
23 Genomic basis for RNA alterations in cancer PCAWG Transcriptome Core Group et al. · Nature Open access1,461 authors 5 Feb 2020 425
24 The landscape of viral associations in human cancers Marc Zapatka et al. · Nature Genetics Open access1,355 authors 5 Feb 2020 412
25 eggNOG 6.0: enabling comparative genomics across 12 535 organisms Ana Hernández-Plaza, Damian Szklarczyk, Jorge Botas et al. · Nucleic Acids Research Open access 24 Oct 2022 378
26 iPath3.0: interactive pathways explorer v3 Youssef Darzi, Ivica Letunić, Peer Bork et al. · Nucleic Acids Research Open access 11 Apr 2018 327
27 Microbiome and metabolome features of the cardiometabolic disease spectrum Sébastien Fromentin et al. · Nature Medicine Open access Feb 2022 306
28 Positioning hydrogen atoms by optimizing hydrogen-bond networks in protein structures Rob W W Hooft, Chris Sander, Gerrit Vriend · Proteins Structure Function and Bioinformatics Dec 1996 305
29 Imidazole propionate is increased in diabetes and associated with dietary patterns and altered microbial ecology Antonio Molinaro et al. · Nature Communications Open access110 authors 18 Nov 2020 288
30 Activation of Blood Coagulation After Cardiac Arrest Is Not Balanced Adequately by Activation of Endogenous Fibrinolysis Bernd Walter Böttiger, J. Motsch, Hubert Bohrer et al. · Circulation Nov 1995 260
31 Towards the biogeography of prokaryotic genes Luis Pedro Coelho et al. · Nature Open access 15 Dec 2021 253
32 Combinatorial, additive and dose-dependent drug–microbiome associations Sofia Kirke Forslund et al. · Nature Open access119 authors 8 Dec 2021 247
33 A deep learning system accurately classifies primary and metastatic cancers using passenger mutation patterns Wei Jiao et al. · Nature Communications Open access1,385 authors 5 Feb 2020 246
34 Integrative pathway enrichment analysis of multivariate omics data Marta Paczkowska et al. · Nature Communications Open access1,460 authors 5 Feb 2020 243
35 Overexpression of the Transcription Factor GROWTH-REGULATING FACTOR5 Improves Transformation of Dicot and Monocot Species Jixiang Kong, Susana Martin‐Ortigosa, John J. Finer et al. · Frontiers in Plant Science Open access 12 Oct 2020 207
36 Use cases, best practice and reporting standards for metabolomics in regulatory toxicology Mark R. Viant, Timothy M. D. Ebbels, Richard D. Beger et al. · Nature Communications Open access 10 Jul 2019 204
37 Landscape of mobile genetic elements and their antibiotic resistance cargo in prokaryotic genomes Supriya Khedkar, Georgy Smyshlyaev, Ivica Letunić et al. · Nucleic Acids Research Open access 11 Mar 2022 195
38 Cancer LncRNA Census reveals evidence for deep functional conservation of long noncoding RNAs in tumorigenesis Joana Carlevaro-Fita et al. · Communications Biology Open access1,462 authors 5 Feb 2020 195
39 proGenomes: a resource for consistent functional and taxonomic annotations of prokaryotic genomes Daniel R. Mende, Ivica Letunić, Jaime Huerta‐Cepas et al. · Nucleic Acids Research Open access 17 Oct 2016 161
40 Influenza Vaccination Is Associated With a Reduced Risk of Stroke Armin Grau, Beate Fischer, Cordula Barth et al. · Stroke Open access 10 Jun 2005 145
41 Genomic footprints of activated telomere maintenance mechanisms in cancer Lina Sieverling et al. · Nature Communications Open access1,414 authors 5 Feb 2020 143
42 Divergent mutational processes distinguish hypoxic and normoxic tumours Vinayak Bhandari et al. · Nature Communications Open access1,328 authors 5 Feb 2020 143
43 Impairment of gut microbial biotin metabolism and host biotin status in severe obesity: effect of biotin and prebiotic supplementation on improved metabolism Eugeni Belda et al. · Gut Open access 11 Jan 2022 141
44 Sex differences in oncogenic mutational processes Constance H. Li et al. · Nature Communications Open access1,376 authors 28 Aug 2020 130
45 Pathway and network analysis of more than 2500 whole cancer genomes Matthew A. Reyna et al. · Nature Communications Open access1,454 authors 5 Feb 2020 120
46 PTMcode v2: a resource for functional associations of post-translational modifications within and between proteins Pablo Mínguez, Ivica Letunić, Luca Parca et al. · Nucleic Acids Research Open access 31 Oct 2014 115
47 proGenomes2: an improved database for accurate and consistent habitat, taxonomic and functional annotations of prokaryotic genomes Daniel R. Mende, Ivica Letunić, Oleksandr M. Maistrenko et al. · Nucleic Acids Research Open access 18 Oct 2019 107
48 SPIRE: a Searchable, Planetary-scale mIcrobiome REsource Thomas Schmidt, Anthony Fullam, Pamela Ferretti et al. · Nucleic Acids Research Open access 11 Oct 2023 96
49 proGenomes3: approaching one million accurately and consistently annotated high-quality prokaryotic genomes Anthony Fullam et al. · Nucleic Acids Research Open access 21 Nov 2022 91
50 Whole Blood DNA Methylation Signatures of Diet Are Associated With Cardiovascular Disease Risk Factors and All-Cause Mortality Jiantao Ma et al. · Circulation Genomic and Precision Medicine Open access 11 Jun 2020 89

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.