Most cited papers from BioPAL (United States)

BioPAL (United States)

What are the most cited papers from BioPAL (United States)?

The most cited paper from BioPAL (United States) is "Simultaneous targeting of multiple disease mediators by a dual-variable-domain immunoglobulin" (Chengbin Wu, Ying Hua, Christine M. Grinnell et al., 2007), with 345 citations. Next come "Regulation of Protein Phosphatase 2A Activity by Caspase-3 during Apoptosis" (152) and "Stable labeled microspheres to measure perfusion: validation of a neutron activation assay technique" (136).

Published TypeFieldAccessCitations

Showing 41 of 41 papers. Every paper is listed.

Most cited papers, sortable by citations and release date
#	Paper
1	Simultaneous targeting of multiple disease mediators by a dual-variable-domain immunoglobulin Chengbin Wu, Ying Hua, Christine M. Grinnell et al. · Nature Biotechnology	14 Oct 2007	345
2	Regulation of Protein Phosphatase 2A Activity by Caspase-3 during Apoptosis Maxine Fico Santoro, R. R. Annand, Molly M. Robertson et al. · Journal of Biological Chemistry Open access	May 1998	152
3	Stable labeled microspheres to measure perfusion: validation of a neutron activation assay technique Christopher P. Reinhardt, Seth Dalhberg, Mark A. Tries et al. · American Journal of Physiology-Heart and Circulatory Physiology	2001	136
4	Selective pyrrolo-pyrimidine inhibitors reveal a necessary role for Src family kinases in Bcr–Abl signal transduction and oncogenesis Matthew B. Wilson, Steven J. Schreiner, Hyun-Jung Choi et al. · Oncogene	19 Nov 2002	134
5	Characterization of Noncovalent Complexes of Recombinant Human Monoclonal Antibody and Antigen Using Cation Exchange, Size Exclusion Chromatography, and BIAcore Ling C. Santora, Zehra Kaymakcalan, Paul Sakorafas et al. · Analytical Biochemistry	Dec 2001	107
6	CD11c as a Transcriptional Biomarker to Predict Response to Anti-TNF Monotherapy With Adalimumab in Patients With Rheumatoid Arthritis Bruno Stuhlmüller, Thomas Häupl, M. Mar Abad Hernández et al. · Clinical Pharmacology & Therapeutics	23 Dec 2009	92
7	Characterization of lower molecular weight artifact bands of recombinant monoclonal IgG1 antibodies on non-reducing SDS-PAGE Hongcheng Liu, Georgeen Gaza‐Bulseco, Chris M. Chumsae et al. · Biotechnology Letters	3 Jul 2007	77
8	Ultrasmall Mixed Ferrite Colloids as Multidimensional Magnetic Resonance Imaging, Cell Labeling, and Cell Sorting Agents Ernest Groman, Jacqueline Bouchard, Christopher P. Reinhardt et al. · Bioconjugate Chemistry	18 Oct 2007	76
9	HER2 and HLA-A02 dual CAR-T cells utilize LOH in a NOT logic gate to address on-target off-tumor toxicity David Bassan, Leehee Weinberger, Jason Yi et al. · Journal for ImmunoTherapy of Cancer* Open access	Dec 2023	35
10	Impaired Sleep, Circadian Rhythms and Neurogenesis in Diet-Induced Premature Aging Alexander J. Stankiewicz, Erin McGowan, Lili Yu et al. · International Journal of Molecular Sciences Open access	26 Oct 2017	29
11	Method to quantify tail vein injection technique in small animals. Ernest Groman, Christopher P. Reinhardt · PubMed	2004	29
12	Rodent Models of Aging Bone: An Update Farhan A. Syed, Terry L. Melim · Current Osteoporosis Reports	14 Sep 2011	27
13	Resistance to ABT-737 in activated T lymphocytes: molecular mechanisms and reversibility by inhibition of the calcineurin–NFAT pathway Pietro E. Cippà, Anna Kraus, Maja T. Lindenmeyer et al. · Cell Death and Disease Open access	19 Apr 2012	23
14	Rationale and development of multispecific antibody drugs Jijie Gu, Tariq Ghayur · Expert Review of Clinical Pharmacology	Jul 2010	15
15	Looking through Brains with Fast Passive CLARITY: Zebrafish, Rodents, Non-human Primates and Humans Farzad Mortazavi, Alexander J. Stankiewicz, Irina V. Zhdanova · BIO-PROTOCOL Open access	2019	14
16	Suppression of CD4+ T cell activation by a novel inhibitor of Src family kinases Bradford L. McRae, Craig D. Wallace, Kathleen Fitzgerald Dixon et al. · International Immunopharmacology	14 Dec 2004	14
17	Estimation of glomerular filtration rate in dogs by plasma clearance of gadolinium diethylenetriamine pentaacetic acid as measured by use of an ELISA Benjamin G. Nolan, Linda Anne Ross, Dennis E. Vaccaro et al. · American Journal of Veterinary Research Open access	31 Mar 2009	12
18	Cell Tracking Using Nanoparticles Dennis E. Vaccaro, Meiheng Yang, James S. Weinberg et al. · Journal of Cardiovascular Translational Research	7 Jul 2008	12
19	Functional immunoassay technology (FIT), a new approach for measuring physiological functions: application of FIT to measure glomerular filtration rate (GFR) Christopher P. Reinhardt, Michael J. St. Germain, Ernest Groman et al. · American Journal of Physiology-Renal Physiology Open access	4 Sep 2008	11
20	Prenatal cocaine exposure disrupts the dopaminergic system and its postnatal responses to cocaine Elizabeth Riley, V. Maymi, S. Pawlyszyn et al. · Genes Brain & Behavior Open access	13 Dec 2017	9
21	Adalimumab Jochen G. Salfeld, H. Küpper Book chapter	2007	8
22	Polycationic Nanoparticles: (1) Synthesis of a Polylysine-MION Conjugate and its Application in Labeling Fibroblasts Ernest Groman, Meiheng Yang, Christopher P. Reinhardt et al. · Journal of Cardiovascular Translational Research	13 Jan 2009	8
23	SIRB, sans iron oxide rhodamine B, a novel cross‐linked dextran nanoparticle, labels human neuroprogenitor and SH‐SY5Y neuroblastoma cells and serves as a USPIO cell labeling control Wei‐Bin Shen, Dennis E. Vaccaro, Paul S. Fishman et al. · Contrast Media & Molecular Imaging	25 Jan 2016	7
24	Neutron-activation analysis: A novel method for the assay of iohexol David A. Albert, Andrew Jason Cohen, Didier A. Mandelbrot et al. · Journal of Laboratory and Clinical Medicine	Feb 2003	7
25	Dual-Variable Domain Immunoglobulin (DVD-Ig™) Technology: A Versatile, Novel Format for the Next Generation of Dual-Targeting Biologics Edit Tarcsa, Wolfgang Fraunhofer, Tariq Ghayur et al. Book chapter	2011	7
26	Cell Kinetics in the Adult Neurogenic Niche and Impact of Diet-Induced Accelerated Aging Alexander J. Stankiewicz, Farzad Mortazavi, Peter V. Kharchenko et al. · Journal of Neuroscience Open access	8 Feb 2019	6
27	Vital parameters need to be in print David W. Borhani · Nature	20 Sep 2001	4
28	Generation and Characterization of a Dual Variable Domain Immunoglobulin (DVD-Ig™) Molecule Chengbin Wu, Tariq Ghayur, Jochen G. Salfeld Book chapter	2010	3
29	Aspects of Isotype Selection Zehra Kaymakcalan, Alexander R. Ibraghimov, Andrew G. Goodearl et al. Book chapter	2010	2
30	eGFR--Why read tea leaves when you can make the measurement? Christopher P. Reinhardt, Ernest Groman, Dennis E. Vaccaro · Nephrology Dialysis Transplantation Open access	16 Feb 2009	2
31	RANKL expression in human T-lymphocytes requires cooperative signaling through the T-cell receptor and adhesion molecule CD2 Bohdan P. Harvey, Zehra Kaymakcalan · Journal of Translational Medicine Open access	Nov 2010	2
32	Hepatocyte Asialoglycoprotein Receptor Assay Using Stable Isotopes and Neutron Activation Analysis Ernest Groman, Christopher P. Reinhardt · Clinical Chemistry	Sep 2000	2
33	Chemical-Class Submixture Screening Reveals Drivers of Endocrine Disruption in Personalized Human Blood POP Mixtures Denise Strand, Paula Pierozan, Luã Tainã Costa Reis et al. · Environmental Science & Technology Open access	3 Feb 2026	1
34	Overview on the Use of Therapeutic Antibodies in Drug Discovery Michael Roguska, Zehra Kaymakcalan, Jochen G. Salfeld · Current Protocols in Pharmacology	Dec 2004	1
35	The novel atypical antipsychotic cariprazine demonstrates dopamine D2 receptor-dependent partial agonist actions on rat mesencephalic dopamine neuronal activity. Sarah Delcourte, Béla Kiss, Nika Adham et al. · HAL (Le Centre pour la Communication Scientifique Directe) Conference paper	21 May 2021	0
36	Invariant relationship unites REM and NonREM sleep Irina V. Zhdanova, Vasili A. Kharchenko · bioRxiv (Cold Spring Harbor Laboratory) PreprintOpen access	9 May 2023	0
37	CtrΔe13, a Calcitonin Receptor Isoform Lacking 14 Amino Acids in Transmembrane Helix 7: Structure and Topology Maria Pellegrini, Veronique Grignoux, William C. Horne et al. Book chapter	2001	0
38	Characterizing the Interactions Between Cholecystokinin and the G-Protein Coupled Receptors CCK1 and CCK2: An NMR-Based Study Craig Giragossian, Maria Pellegrini, Dale F. Mierke Book chapter	2001	0
39	Functional Characterization of Antibodies Neutralizing Soluble Factors In Vitro and In Vivo Geertruida M. Veldman, Zehra Kaymakcalan, Renee Miller et al. Book chapter	2010	0
40	Probing the Importance of the N-Terminal Helix of Parathyroid Hormone: Introduction of Cyclohexylalanine to Tether to the Membrane Maria Pellegrini, Andrea Piserchio, Dale F. Mierke et al. Book chapter	2001	0
41	Biologics in Crohn’s Disease and Ulcerative Colitis: Focus on Tumor Necrosis Factor Antagonists Jochen G. Salfeld, Paul Rutgeerts Book chapter	2007	0

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.