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Most cited papers from Biostatistical Consulting (United States)

What are the most cited papers from Biostatistical Consulting (United States)?

The most cited paper from Biostatistical Consulting (United States) is "Decreased heart rate variability and its association with increased mortality after acute myocardial infarction" (Robert E. Kleiger, J. Philip Miller, J. Thomas Bigger et al., 1987), with 4,025 citations. Next come "Defining the clinical course of multiple sclerosis" (3,202) and "The Triple Negative Paradox: Primary Tumor Chemosensitivity of Breast Cancer Subtypes" (2,135).

Showing 50 of 60 papers. Every paper with more than 266 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 Decreased heart rate variability and its association with increased mortality after acute myocardial infarction Robert E. Kleiger, J. Philip Miller, J. Thomas Bigger et al. · The American Journal of Cardiology Open access Feb 1987 4,025
2 Defining the clinical course of multiple sclerosis FRED D. LUBLIN et al. · Neurology Open access 28 May 2014 3,202
3 The Triple Negative Paradox: Primary Tumor Chemosensitivity of Breast Cancer Subtypes Lisa A. Carey, Elizabeth Claire Dees, Lynda Sawyer et al. · Clinical Cancer Research 15 Apr 2007 2,135
4 Preoperative Chemotherapy in Patients With Operable Breast Cancer: Nine-Year Results From National Surgical Adjuvant Breast and Bowel Project B-18 Norman Wolmark, J. Wang, Eleftherios Mamounas et al. · JNCI Monographs Open access Dec 2001 1,321
5 Phase II Trial of Bevacizumab and Irinotecan in Recurrent Malignant Glioma James J. Vredenburgh, Annick Desjardins, James E. Herndon et al. · Clinical Cancer Research 15 Feb 2007 1,079
6 Accuracy of CT Colonography for Detection of Large Adenomas and Cancers C. Daniel Johnson et al. · New England Journal of Medicine Open access 18 Sep 2008 1,041
7 Incidence, risk factors, and outcomes of osteonecrosis of the jaw: integrated analysis from three blinded active-controlled phase III trials in cancer patients with bone metastases Fred Saad, Janet Elizabeth Brown, Catherine H. Van Poznak et al. · Annals of Oncology Open access 11 Oct 2011 825
8 Durvalumab With or Without Tremelimumab for Patients With Metastatic Pancreatic Ductal Adenocarcinoma Eileen Mary O'Reilly, Do‐Youn Oh, Neesha C. Dhani et al. · JAMA Oncology Open access 18 Jul 2019 798
9 Diversity and clonal selection in the human T-cell repertoire Qian Qi, Yi Sha Liu, Yong Cheng et al. · Proceedings of the National Academy of Sciences Open access 25 Aug 2014 797
10 Prevalence of Hip Symptoms and Radiographic and Symptomatic Hip Osteoarthritis in African Americans and Caucasians: The Johnston County Osteoarthritis Project Joanne M. Jordan, Charles G. Helmick, Jordan B. Renner et al. · The Journal of Rheumatology Open access 13 Mar 2009 746
11 Obesity and Risk for Chronic Renal Failure Elisabeth Ejerblad, Carl Michael Fored, Per Lindblad et al. · Journal of the American Society of Nephrology 26 Apr 2006 684
12 Use of Tissue-Type Plasminogen Activator for Acute Ischemic Stroke Irene L. Katzan, Anthony J. Furlan, Lynne E. Lloyd et al. · JAMA Mar 2000 659
13 Gene selection for sample classification based on gene expression data: study of sensitivity to choice of parameters of the GA/KNN method Leping Li, Clarice Ring Weinberg, Thomas A. Darden et al. · Bioinformatics Open access Dec 2001 648
14 Incidence and Risk Factors for Side Effects of Spinal Anesthesia Randall L. Carpenter, Robert A. Caplan, David Brown et al. · Anesthesiology Open access Jun 1992 637
15 Bevacizumab plus Ipilimumab in Patients with Metastatic Melanoma Frank Stephen Hodi et al. · Cancer Immunology Research Open access 21 Apr 2014 606
16 Persistent Activation of Stat3 Signaling Induces Survivin Gene Expression and Confers Resistance to Apoptosis in Human Breast Cancer Cells Tanya Gritsko, Ann Houston Williams, James Turkson et al. · Clinical Cancer Research Open access 2006 569
17 Residual NADPH Oxidase and Survival in Chronic Granulomatous Disease Douglas Byron Kuhns, W. Gregory Alvord, Theo Heller et al. · New England Journal of Medicine Open access 29 Dec 2010 566
18 Effectiveness of prenatal treatment for congenital toxoplasmosis: a meta-analysis of individual patients' data Rodolphe Thiébaut · The Lancet ReviewOpen access 2007 541
19 Hepatocellular Carcinoma: Diagnostic Performance of Multidetector CT and MR Imaging—A Systematic Review and Meta-Analysis Yoon Jin Lee, Jeong Min Lee, Ji Sung Lee et al. · Radiology Review 5 Jan 2015 528
20 Approval Summary: Sunitinib for the Treatment of Imatinib Refractory or Intolerant Gastrointestinal Stromal Tumors and Advanced Renal Cell Carcinoma Vicki L. Goodman, Edwin P. Rock, Ramzi N. Dagher et al. · Clinical Cancer Research Open access Mar 2007 502
21 Real-World Performance of HER2 Testing--National Surgical Adjuvant Breast and Bowel Project Experience Soonmyung Paik, Jennifer Bryant, Elizabeth Tan-Chiu et al. · JNCI Journal of the National Cancer Institute Open access 5 Jun 2002 497
22 Testosterone and Dihydrotestosterone Tissue Levels in Recurrent Prostate Cancer Mark Anton Titus, Michael J. Schell, Fred Bjørn Lih et al. · Clinical Cancer Research Open access Jul 2005 494
23 Genome-Informed Targeted Therapy for Osteosarcoma Leanne C. Sayles et al. · Cancer Discovery Open access 28 Sep 2018 485
24 Non-monotonic dose-response relationships and endocrine disruptors: a qualitative method of assessment Fabien Lagarde, Claire Beausoleil, Scott M. Belcher et al. · Environmental Health Open access 11 Feb 2015 458
25 Selection of Potential Markers for Epithelial Ovarian Cancer with Gene Expression Arrays and Recursive Descent Partition Analysis Karen H. Lu, Andrea P. Patterson, Lin Wang et al. · Clinical Cancer Research 15 May 2004 446
26 Gene Expression Signatures for Predicting Prognosis of Squamous Cell and Adenocarcinomas of the Lung Mitch Raponi, Yi Zhang, Jack X. Yu et al. · Cancer Research Aug 2006 440
27 Spontaneous and therapeutic prognostic factors in adult hemispheric World Health Organization Grade II gliomas: a series of 1097 cases Laurent Capelle, Denys Fontaine, Emmanuel Mandonnet et al. · Journal of neurosurgery 15 Mar 2013 423
28 Molecular Classification and Prognostication of Adrenocortical Tumors by Transcriptome Profiling Thomas J. Giordano, Rork D. Kuick, Tobias Else et al. · Clinical Cancer Research Open access 15 Jan 2009 402
29 Insulin-like Growth Factor-I–Dependent Up-regulation of ZEB1 Drives Epithelial-to-Mesenchymal Transition in Human Prostate Cancer Cells Tisheeka R. Graham, Haiyen E. Zhau, Valerie Odero-Marah et al. · Cancer Research Apr 2008 388
30 Smoking and Perioperative Outcomes Alparslan Turan, Edward J. Mascha, Dmitry Roberman et al. · Anesthesiology 4 Mar 2011 388
31 Randomized Controlled Clinical Trial of Surgery Versus No Surgery in Patients with Mild Asymptomatic Primary Hyperparathyroidism D. Sudhaker Rao, Evelyn R. Phillips, George Divine et al. · The Journal of Clinical Endocrinology & Metabolism Nov 2004 384
32 Toxicological Function of Adipose Tissue: Focus on Persistent Organic Pollutants Michele A. La Merrill, Claude Emond, Min Ji Kim et al. · Environmental Health Perspectives Open access 5 Dec 2012 382
33 Hypoxia Is Important in the Biology and Aggression of Human Glial Brain Tumors Sydney M. Evans, Kevin D Judy, Isolde Dunphy et al. · Clinical Cancer Research 15 Dec 2004 368
34 Prenatal undernutrition and cognitive function in late adulthood Susanne R. de Rooij, Hans Wouters, Julie E. Yonker et al. · Proceedings of the National Academy of Sciences Open access 13 Sep 2010 368
35 Endoscopic pituitary surgery: a systematic review and meta-analysis Abtin Tabaee, Vijay Kumar Anand, Yolanda Barrón et al. · Journal of neurosurgery Review Sep 2009 364
36 Preoperative Clinic Visits Reduce Operating Room Cancellations and Delays Marla B. Ferschl, Avery Tung, BobbieJean Sweitzer et al. · Anesthesiology Open access 28 Sep 2005 358
37 Analysis of small sample size studies using nonparametric bootstrap test with pooled resampling method Alok Kumar Dwivedi, Indika V. Mallawaarachchi, Luis Andres Alvarado · Statistics in Medicine 9 Mar 2017 343
38 Biomechanics of the Human Posterior Sclera: Age- and Glaucoma-Related Changes Measured Using Inflation Testing Baptiste Coudrillier, Jing Tian, Stephen Alexander et al. · Investigative Ophthalmology & Visual Science Open access 7 Mar 2012 342
39 Homozygous Deletions and Chromosome Amplifications in Human Lung Carcinomas Revealed by Single Nucleotide Polymorphism Array Analysis Xiaojun Zhao, Barbara A. Weir, Thomas LaFramboise et al. · Cancer Research Open access Jul 2005 341
40 Long-term survival following a single treatment of kidney tumors with multiwalled carbon nanotubes and near-infrared radiation Andrew R. Burke, Xuanfeng Ding, Ravi N. Singh et al. · Proceedings of the National Academy of Sciences Open access 21 Jul 2009 338
41 Identification of GATA3 as a Breast Cancer Prognostic Marker by Global Gene Expression Meta-analysis Rohit S Mehra, Sooryanarayana Varambally, Lei Ding et al. · Cancer Research 15 Dec 2005 335
42 Transcriptional activation of integrin β6 during the epithelial-mesenchymal transition defines a novel prognostic indicator of aggressive colon carcinoma Richard C. Bates, David I. Bellovin, Courtney Brown et al. · Journal of Clinical Investigation Open access 20 Jan 2005 328
43 Targeting Mammalian Target of Rapamycin Synergistically Enhances Chemotherapy-Induced Cytotoxicity in Breast Cancer Cells Wallace H. Mondesire, Weiguo Jian, Haixia Zhang et al. · Clinical Cancer Research 15 Oct 2004 321
44 Randomized Phase III Intergroup Trial of Isotretinoin to Prevent Second Primary Tumors in Stage I Non-Small-Cell Lung Cancer Scott Michael Lippman, J. J. Lee, Daniel D. Karp et al. · JNCI Journal of the National Cancer Institute 18 Apr 2001 321
45 Gene Expression Differences Associated with Human Papillomavirus Status in Head and Neck Squamous Cell Carcinoma Robbert J.C. Slebos, Yajun Yi, Kim Adams Ely et al. · Clinical Cancer Research Feb 2006 318
46 The Swedish Knee Arthroplasty Register Otto Robertsson, Jonas Ranstam, Martin Sundberg et al. · Bone and Joint Research Open access Jul 2014 318
47 Efficacy of Tranexamic Acid in Pediatric Craniosynostosis Surgery Susan M. Goobie, Petra M. Meier, Luis Marcelo Pereira et al. · Anesthesiology Mar 2011 317
48 Chronic Inflammation Is Associated With Low Physical Function in Older Adults Across Multiple Comorbidities Tina E. Brinkley, Xiaoyan Leng, Michael E. Miller et al. · The Journals of Gerontology Series A Open access 4 Feb 2009 315
49 Total Hip Acetabular Component Position Affects Component Loosening Rates STEPHEN A. YODER, RICHARD A. BRAND, Douglas R. Pedersen et al. · Clinical Orthopaedics and Related Research Mar 1988 301
50 Perceived stress in survivors of suicide: Psychometric properties of the Perceived Stress Scale Ann M. Mitchell, Patricia B. Crane, Yookyung Kim · Research in Nursing & Health 30 Apr 2008 295

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.