Science Explorer Back to mapMap
Institution · BioSystem (Germany)

Most cited papers from BioSystem (Germany)

What are the most cited papers from BioSystem (Germany)?

The most cited paper from BioSystem (Germany) is "Dual-color fluorescence cross-correlation spectroscopy for multicomponent diffusional analysis in solution" (Petra Schwille, Franz‐Josef Meyer‐Almes, Rudolf W. Rigler, 1997), with 836 citations. Next come "Attributes of short linear motifs" (676) and "Fluorescence-intensity distribution analysis and its application in biomolecular detection technology" (460).

Showing 50 of 56 papers. Every paper is listed.

Most cited papers, sortable by citations and release date
#Paper
1 Dual-color fluorescence cross-correlation spectroscopy for multicomponent diffusional analysis in solution Petra Schwille, Franz‐Josef Meyer‐Almes, Rudolf W. Rigler · Biophysical Journal Open access Apr 1997 836
2 Attributes of short linear motifs Norman E. Davey, Kim Van Roey, Robert J. Weatheritt et al. · Molecular BioSystems 12 Sep 2011 676
3 Fluorescence-intensity distribution analysis and its application in biomolecular detection technology Peet Kask, Kaupo Palo, Dirk Ullmann et al. · Proceedings of the National Academy of Sciences Open access 23 Nov 1999 460
4 Molecular mechanisms of biocatalytic desulfurization of fossil fuels Kevin A. Gray, Olga S. Pogrebinsky, Gregory T. Mrachko et al. · Nature Biotechnology Dec 1996 353
5 Two-Dimensional Fluorescence Intensity Distribution Analysis: Theory and Applications Peet Kask, Kaupo Palo, Nicolas Fay et al. · Biophysical Journal Open access Apr 2000 153
6 Fluorescence cross-correlation: A new concept for polymerase chain reaction Rudolf W. Rigler, Zeno Földes‐Papp, Franz‐Josef Meyer‐Almes et al. · Journal of Biotechnology Aug 1998 124
7 Fluorescence Intensity Multiple Distributions Analysis: Concurrent Determination of Diffusion Times and Molecular Brightness Kaupo Palo, Ülo Mets, Stefan Jäger et al. · Biophysical Journal Open access Dec 2000 120
8 Statistical accuracy in fluorescence fluctuation experiments Peet Kask, Roman Günther, Peter Axhausen · European Biophysics Journal 27 Jan 1997 105
9 An automated prediction of MHC class I-binding peptides based on positional scanning with peptide libraries Keiko Udaka, Karl‐Heinz Wiesmüller, Stefan Kienle et al. · Immunogenetics 3 Aug 2000 82
10 Dielectrophoretic manipulation of suspended submicron particles Thomas Schnelle, Torsten Müller, Gabriele Gradl et al. · Electrophoresis 2000 78
11 Towards a general procedure for sequencing single DNA molecules Jens S. Stephan, Klaus Dörre, Susanne Brakmann et al. · Journal of Biotechnology Apr 2001 46
12 Minireview: Fluorescence Correlation Spectroscopy (FCS) - A Highly Sensitive Method to Analyze Drug/Target Interactions Sylvia Sterrer, Karsten Henco · Journal of Receptors and Signal Transduction 1997 46
13 Transport of artificial virus-like nanocarriers through intestinal monolayers via microfold cells Tianjian Tong, Yijun Qi, Luke D. Bussiere et al. · Nanoscale Open access 2020 35
14 “Nuclear FGF Receptor‐1 and CREB Binding Protein: An Integrative Signaling Module” Michal K. Stachowiak, Barbara G. Birkaya, John M. Aletta et al. · Journal of Cellular Physiology Open access 11 Dec 2014 35
15 Cell Sorting in Microfluidic Systems Pieter Telleman, Ulrik Larsen, John Philip et al. Book chapter 1998 34
16 A Novel and Robust Homogeneous Fluorescence-Based Assay Using Nanoparticles for Pharmaceutical Screening and Diagnostics Sabine Schaertl, Franz‐Josef Meyer‐Almes, Eloisa Lopez‐Calle et al. · SLAS DISCOVERY Open access Jun 2000 32
17 Personalized cancer medicine—advances and socio-economic challenges David Jackson, Anil K. Sood · Nature Reviews Clinical Oncology ReviewOpen access 11 Oct 2011 31
18 Inhibition of endotoxin-induced TNF-α production in macrophages by 5Z-7-oxo-zeaenol and other fungal resorcylic acid lactones Philip B. Rawlins, Thomas Mander, Roya Sadeghi et al. · International Journal of Immunopharmacology Dec 1999 27
19 Receptor–Ligand Interactions Studied with Homogeneous Fluorescence-Based Assays Suitable for Miniaturized Screening Andreas A. Scheel, Bettina Funsch, Michael Paul Busch et al. · SLAS DISCOVERY Open access Feb 2001 26
20 Miniaturized plastic micro plates for applications in HTS Monika Niggemann, W. Ehrfeld, Lutz Weber et al. · Microsystem Technologies 17 Dec 1999 22
21 Beyond uHTS: ridiculously HTS? T. H. Mander · Drug Discovery Today Jun 2000 21
22 Distribution Patterns of Zooplankton in Tomales Bay, California Wim Kimmerer · Estuaries Jun 1993 19
23 Phylogenetic distance in Great Salt Lake microbial communities JJ Parnell, G. Rompato, Todd A. Crowl et al. · Aquatic Microbial Ecology Open access 28 Jun 2011 16
24 Systemintegration of microsystems/chip elements in miniaturized automata for high-throughput synthesis and screening in biology, biochemistry and chemistry Andreas Schober, Gregor Schlingloff, Antje Thamm et al. · Microsystem Technologies 12 Dec 1997 16
25 Rare Event Cell Surging in a Microfluidic System for Application in Prenatal Diagnosis Anders Wolff, Ulrik Larsen, Gert Blankenstein et al. Book chapter 1998 16
26 A DNA-BINDING PEPTIDE FROM A PHAGE DISPLAY LIBRARY Julian Wölcke, Elmar G. Weinhold · Nucleosides Nucleotides & Nucleic Acids 31 Mar 2001 14
27 Effects of chemical modification of lysine residues in trypsin Christian Elsner, Sibylla Grahn, Sebastian Bauer et al. · Journal of Molecular Catalysis B Enzymatic Feb 2000 14
28 Growth kinetics of a bacteriophage in continuous culture Andreas Schwienhorst, Björn F. Lindemann, Manfred Eigen · Biotechnology and Bioengineering 20 Apr 1996 14
29 The New Serine-Threonine Kinase, Qik, Is a Target of the qin Oncogene Yu Xia, Zhihong Zhang, Ulrich Kruse et al. · Biochemical and Biophysical Research Communications Sep 2000 14
30 Strategies for folding of affinity tagged proteins using GroEL and osmolytes Hiroo Katayama, Mitchell R. McGill, Andrew Kearns et al. · Journal of Structural and Functional Genomics Open access 11 Dec 2008 10
31 Promoter selection for the cytosine deaminase suicide gene constructs in gastric cancer Susanne Aberle, Nicola Schug, Rabea Mathlouthi et al. · European Journal of Gastroenterology & Hepatology 2004 10
32 Targeted CD47 checkpoint blockade using a mesothelin-directed antibody construct for enhanced solid tumor-specific immunotherapy Anna Reischer et al. · Cancer Immunology Immunotherapy Open access 22 May 2025 9
33 New Micro Devices for Single Cell Analysis, Cell Sorting and Cloning-on-a-Chip: The CytoconTM Instrument Gabriele Gradl, Torsten Müller, Annette Pfennig et al. Book chapter 2000 6
34 TET dioxygenases localize at splicing speckles and promote RNA splicing Florian D. Hastert, Jasmin Weber, Christina Bauer et al. · Nucleus Open access 27 Jul 2025 5
35 Capture of Human Neuromesodermal and Posterior Neural Tube Axial Stem Cells Dolunay Kelle et al. · bioRxiv (Cold Spring Harbor Laboratory) PreprintOpen access 29 Mar 2024 5
36 TNF-α and IFN-γ differentially regulate AML cell susceptibility to CD70-antibody-mediated cytotoxicity Monika Sponheimer et al. · Journal for ImmunoTherapy of Cancer Open access Dec 2025 3
37 Protease-Catalyzed Peptide Synthesis Dirk Ullmann, Hans‐Dieter Jakubke Book chapter 1999 3
38 To Outsource in Lead Discovery: The Devil or the Deep Blue Sea? Thomas Mander, Rodney J. Turner · SLAS DISCOVERY Open access Jun 2000 3
39 High-throughput screening brings in the crops Timm Jessen · Drug Discovery Today Dec 2000 3
40 Dielektrische Mikrofeldkäfige: Mit elektrischen Hochfrequenzfeldern lassen sich Zellen, Viren und Makromoleküle festhalten und umherschieben Günter Führ, Thomas Schnelle · Physikalische Blätter 2001 3
41 Repertoire forecast of MHC class I binding peptides with peptide libraries Keiko Udaka, Karl‐Heinz Wiesmüller, Günther Jung · Major Histocompatibility Complex Book chapter 2000 3
42 Rapid Analysis of Factor V Leiden Mutation by Membrane Mediated Restriction Digestion and Ultra-Thin Layer Gel Electrophoresis András Guttman, Zsolt Rónai, Julia Khandurina et al. · Chromatographia Open access 19 May 2004 2
43 Potent photoswitch for expression of biotherapeutics in mammalian cells by light Jeannette Gebel, Elisa Ciglieri, Rainer Stahl et al. · bioRxiv (Cold Spring Harbor Laboratory) PreprintOpen access 3 Oct 2024 1
44 SERVICE TO THE COMMUNITY OF THE COVID 19 DISASTER (PKM-BC19) IN LIMBUKAN KELURAHAN, SELATAN PAYAKUMBUH DISTRICT, PAYAKUMBUH CITY Rina Yenrina, Krisna Guci · Andalasian International Journal of Social and Entrepreneurial Development Open access 5 Nov 2021 1
45 Application of linear regression to elucidate ileal inevitable flow and digestibility of amino acids and consequences for standardised digestibility system D.O. Akinde · World s Poultry Science Journal 26 May 2016 1
46 Betrachtungen über mikrobiell induzierte Korrosionsvorgänge und deren biologischen Hintergrund Paul Gümpel, Rainer Kreikenbohm, K. Neumann · Materialwissenschaft und Werkstofftechnik Mar 1996 1
47 Tailor made Pharmacokinetics of Peptides by Transient PEGylation Ulrich Hersel, Martina Kreuzer, Harald K. Rau et al. · Advances in experimental medicine and biology Book chapter 2009 1
48 The effectiveness of injectable exoprotectors for recovering facial skin quality. Literature review and clinical observations Zarema Ibragimovna Gazitaeva, Ольга Владимировна Забненкова · Medical alphabet Open access 4 Jun 2025 0
49 Effects of different force moulting methods on performance, egg quality and plasma metabolites in Japanese quails Ali Asghar Saki, S. Roomiani, S. Mirzaei et al. · BULGARIAN JOURNAL OF VETERINARY MEDICINE Open access 2017 0
50 Combinatorial peptide libraries and molecular recognition in T-cell mediated immune response Burkhard T. Fleckenstein, Karl‐Heinz Wiesmüller, Matthias Kalbus et al. · Kluwer Academic Publishers eBooks Book chapter 24 Mar 2006 0

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.