| 1 |
Overcoming the challenges in administering biopharmaceuticals: formulation and delivery strategies
Samir Mitragotri, Paul A. Burke, Róbert Langer · Nature Reviews Drug Discovery
ReviewOpen access |
8 Aug 2014 |
1,696 |
| 2 |
Epidemiology of Fracture Nonunion in 18 Human Bones
Robert Zura, Ze Xiong, Thomas A. Einhorn et al. · JAMA Surgery
Open access |
7 Sep 2016 |
747 |
| 3 |
Acute and Impaired Wound Healing
Tatiana N. Demidova‐Rice, Michael R. Hamblin, Ira M. Herman · Advances in Skin & Wound Care
Open access |
19 Jun 2012 |
723 |
| 4 |
FAIR Principles: Interpretations and Implementation Considerations
Annika Jacobsen et al. · Data Intelligence
Open access |
Nov 2019 |
478 |
| 5 |
Genetic variation in eleven phase I drug metabolism genes in an ethnically diverse population
Joseph F. Solus, Brenda J Arietta, James R. Harris et al. · Pharmacogenomics
|
Oct 2004 |
237 |
| 6 |
GPT-4 Passes the Bar Exam
Daniel Martin Katz, Michael James Bommarito, Shang Gao et al. · SSRN Electronic Journal
PreprintOpen access |
2023 |
206 |
| 7 |
Functional Variant of CYP4A11 20-Hydroxyeicosatetraenoic Acid Synthase Is Associated With Essential Hypertension
James V. Gainer, Aouatef Bellamine, Elliott P. Dawson et al. · Circulation
|
21 Dec 2004 |
198 |
| 8 |
Mode & mechanism of low intensity pulsed ultrasound (LIPUS) in fracture repair
Andrew J. Harrison, Sheldon S. Lin, Neill M. Pounder et al. · Ultrasonics
Open access |
10 Apr 2016 |
194 |
| 9 |
Healing of fracture nonunions treated with low-intensity pulsed ultrasound (LIPUS): A systematic review and meta-analysis
ROSS K. LEIGHTON, John Tracy Watson, Peter Vasilios Giannoudis et al. · Injury
ReviewOpen access |
15 May 2017 |
171 |
| 10 |
Depressive disorders: Treatment failures and poor prognosis over the last 50 years
Thomas P. Blackburn · Pharmacology Research & Perspectives
Open access |
3 May 2019 |
141 |
| 11 |
GPT Takes the Bar Exam
Michael James Bommarito, Daniel Martin Katz · SSRN Electronic Journal
PreprintOpen access |
2022 |
121 |
| 12 |
Healing, nonunion, and re-operation after internal fixation of diaphyseal and distal femoral fractures: a systematic review and meta-analysis
Riikka E. Koso, Cristina Terhoeve, R. Grant Steen et al. · International Orthopaedics
Review |
7 Mar 2018 |
121 |
| 13 |
The Complete Set of Predicted Genes from Saccharomyces cerevisiae in a Readily Usable Form
James R. Hudson, Elliott P. Dawson, Kimberly L. Rushing et al. · Genome Research
Open access |
Dec 1997 |
121 |
| 14 |
LexGLUE: A Benchmark Dataset for Legal Language Understanding in English
Ilias Chalkidis, Abhik Jana, Dirk Hartung et al. · SSRN Electronic Journal
PreprintOpen access |
2021 |
110 |
| 15 |
Automated air void analysis of hardened concrete — a Round Robin study
Ulla Hjorth Jakobsen, Claus Pade, Niels Thaulow et al. · Cement and Concrete Research
|
20 Apr 2006 |
105 |
| 16 |
A combination of hydroxytyrosol, omega-3 fatty acids and curcumin improves pain and inflammation among early stage breast cancer patients receiving adjuvant hormonal therapy: results of a pilot study
Noelia Martínez-Jáñez, M. Herrera, Laura Frías et al. · Clinical & Translational Oncology
|
6 Oct 2018 |
101 |
| 17 |
Estrogen Metabolite 16α-Hydroxyestrone Exacerbates Bone Morphogenetic Protein Receptor Type II–Associated Pulmonary Arterial Hypertension Through MicroRNA-29–Mediated Modulation of Cellular Metabolism
Xinping Chen, Megha H. Talati, Joshua P. Fessel et al. · Circulation
Open access |
20 Oct 2015 |
96 |
| 18 |
Treatment of chronic (>1 year) fracture nonunion: Heal rate in a cohort of 767 patients treated with low-intensity pulsed ultrasound (LIPUS)
Robert Zura, Gregory J. Della Rocca, Samir D. Mehta et al. · Injury
Open access |
29 May 2015 |
96 |
| 19 |
Natural Language Processing in the Legal Domain
Dirk Hartung, Daniel Martin Katz, Michael James Bommarito et al. · SSRN Electronic Journal
PreprintOpen access |
2023 |
82 |
| 20 |
Phase 1 trials of PEGylated recombinant human hyaluronidase PH20 in patients with advanced solid tumours
Jeffrey R. Infante, Ronald Lee Korn, Lee S. Rosen et al. · British Journal of Cancer
Open access |
26 Sep 2017 |
80 |
| 21 |
A BMP/activin A chimera is superior to native BMPs and induces bone repair in nonhuman primates when delivered in a composite matrix
Howard J. Seeherman, Stephen P. Berasi, Christopher T. Brown et al. · Science Translational Medicine
|
24 Apr 2019 |
75 |
| 22 |
Associations between the number of natural teeth and metabolic syndrome in adults
Yong Zhu, James Hollis · Journal Of Clinical Periodontology
|
9 Jan 2015 |
69 |
| 23 |
Gpt as Knowledge Worker: A Zero-Shot Evaluation of (AI)CPA Capabilities
Jillian Bommarito, Michael James Bommarito, Jessica Ann Mefford Katz et al. · SSRN Electronic Journal
PreprintOpen access |
2023 |
60 |
| 24 |
Stratification of amyotrophic lateral sclerosis patients: a crowdsourcing approach
Robert Kueffner et al. · Scientific Reports
Open access107 authors |
24 Jan 2019 |
57 |
| 25 |
Homozygous MTAP deletion in primary human glioblastoma is not associated with elevation of methylthioadenosine
Yasaman Barekatain et al. · Nature Communications
Open access |
9 Jul 2021 |
56 |
| 26 |
Characterization of genomic structure and polymorphisms in the human carbamyl phosphate synthetase I gene
Marshall L Summar, Lynn D. Hall, Angela Eeds et al. · Gene
|
Jun 2003 |
56 |
| 27 |
Ultrasonic Stimulation of Mouse Skin Reverses the Healing Delays in Diabetes and Aging by Activation of Rac1
James A. Roper, Rosalind C. Williamson, Blandine Bally et al. · Journal of Investigative Dermatology
Open access |
16 Jun 2015 |
54 |
| 28 |
Comparison of low‐ and ultralow‐dose computed tomography protocols for quantitative lung and airway assessment
Emily Hammond, Chelsea M. Sloan, John D. Newell et al. · Medical Physics
Open access |
28 Jun 2017 |
53 |
| 29 |
Systematic clinical evidence review of NASHA (Durolane hyaluronic acid) for the treatment of knee osteoarthritis
ROSS K. LEIGHTON, Jane M. Fitzpatrick, Helen J J. Smith et al. · Open Access Rheumatology Research and Reviews
Open access |
May 2018 |
51 |
| 30 |
Characterization of the CYP4A11 gene, a second CYP4A gene in humans
Aouatef Bellamine, Yarong Wang, Michael R. Waterman et al. · Archives of Biochemistry and Biophysics
|
3 Dec 2002 |
51 |
| 31 |
Horizons in Veterinary Precision Oncology: Fundamentals of Cancer Genomics and Applications of Liquid Biopsy for the Detection, Characterization, and Management of Cancer in Dogs
Jason Chibuk, Andi Flory, Kristina M. Kruglyak et al. · Frontiers in Veterinary Science
Open access |
23 Mar 2021 |
49 |
| 32 |
Influence of dispersant structure and mixing speed on concrete slump retention
T. Vickers, Stephen A. Farrington, Jeffrey R. Bury et al. · Cement and Concrete Research
|
15 Jul 2005 |
49 |
| 33 |
Characterization of IgG1 Fc Deamidation at Asparagine 325 and Its Impact on Antibody-dependent Cell-mediated Cytotoxicity and FcγRIIIa Binding
Xiaojun Lu, LeeAnn Machiesky, Niluka De Mel et al. · Scientific Reports
Open access |
15 Jan 2020 |
47 |
| 34 |
Value Driven Innovation in Medical Device Design: A Process for Balancing Stakeholder Voices
F. J. de Ana, Kelly A. Umstead, G. J. Phillips et al. · Annals of Biomedical Engineering
|
12 Mar 2013 |
46 |
| 35 |
An Oral Formulation of YK-4-279: Preclinical Efficacy and Acquired Resistance Patterns in Ewing Sarcoma
Salah-Eddine Lamhamedi-Cherradi, Brian A. Menegaz, Vandhana Ramamoorthy et al. · Molecular Cancer Therapeutics
|
11 May 2015 |
43 |
| 36 |
An Optimized Bioassay for Screening Combined Anticoronaviral Compounds for Efficacy against Feline Infectious Peritonitis Virus with Pharmacokinetic Analyses of GS-441524, Remdesivir, and Molnupiravir in Cats
Sarah Cook, Luke A. Wittenburg, Victoria C. Yan et al. · Viruses
Open access |
Nov 2022 |
42 |
| 37 |
Making Data and Workflows Findable for Machines
Tobias Weigel, Ulrich Schwardmann, Jens Klump et al. · Data Intelligence
Open access |
Nov 2019 |
40 |
| 38 |
All-girls adventure programmes: what are the benefits?
Anja Whittington, Erica Nixon Mack, Nadine W. Budbill et al. · Journal of Adventure Education & Outdoor Learning
|
Jun 2011 |
39 |
| 39 |
Why Remdesivir Failed: Preclinical Assumptions Overestimate the Clinical Efficacy of Remdesivir for COVID-19 and Ebola
Victoria C. Yan, Florian L. Müller · Antimicrobial Agents and Chemotherapy
Open access |
12 Jul 2021 |
38 |
| 40 |
Epilepsy: Mitochondrial connections to the ‘Sacred’ disease
Walter H. Moos, Douglas V. Faller, Ioannis P. Glavas et al. · Mitochondrion
Open access |
13 Aug 2023 |
37 |
| 41 |
Advancing Polymeric Delivery Systems Amidst a Nucleic Acid Therapy Renaissance
Paul A. Burke, Suzie Hwang Pun, Theresa M. Reineke · ACS Macro Letters
Open access |
2 Oct 2013 |
37 |
| 42 |
What Is the Adverse Event Profile After Prophylactic Treatment of Femoral Shaft or Distal Femur Metastases?
Ryan P. McLynn, Nathaniel T. Ondeck, Jonathan Newman Grauer et al. · Clinical Orthopaedics and Related Research
Open access |
28 Sep 2018 |
36 |
| 43 |
Heal rate of metatarsal fractures: A propensity-matching study of patients treated with low-intensity pulsed ultrasound (LIPUS) vs. surgical and other treatments
Peter A. Nolte, Robert B. Anderson, Elton Strauss et al. · Injury
Open access |
14 Sep 2016 |
36 |
| 44 |
Variations in the α2A-adrenergic receptor gene and their functional effects
Daniel Kurnik, Mordechai Muszkat, Chun Li et al. · Clinical Pharmacology & Therapeutics
|
8 Feb 2006 |
34 |
| 45 |
Polytypes of sp2-Bonded Boron Nitride
Bernard Gil, W. Desrat, Adrien Rousseau et al. · Crystals
Open access |
28 May 2022 |
33 |
| 46 |
Catabolism of Fibromodulin in Developmental Rudiment and Pathologic Articular Cartilage Demonstrates Novel Roles for MMP-13 and ADAMTS-4 in C-terminal Processing of SLRPs
Cindy C. Shu, Carl R. Flannery, Christopher B. Little et al. · International Journal of Molecular Sciences
Open access |
29 Jan 2019 |
33 |
| 47 |
An inception cohort analysis to predict nonunion in tibia and 17 other fracture locations
Robert Zura, John Tracy Watson, Thomas A. Einhorn et al. · Injury
Open access |
27 Mar 2017 |
33 |
| 48 |
Variation in the ??2B-adrenergic receptor gene (ADRA2B) and its relationship to vascular response in vivo
Mordechai Muszkat, Daniel Kurnik, Joseph F. Solus et al. · Pharmacogenetics and Genomics
|
Jun 2005 |
33 |
| 49 |
Unleashing the Potential: Designing Antibody-Targeted Lipid Nanoparticles for Industrial Applications with CMC Considerations and Clinical Outlook
Sheryl Wang, Hong Wang, Andrew A. Drabek et al. · Molecular Pharmaceutics
|
20 Dec 2023 |
32 |
| 50 |
Digital Human Modeling in the Occupational Safety and Health Process: An Application in Manufacturing
Mark Christopher Schall, Nathan B. Fethke, Victoria Roemig · IISE Transactions on Occupational Ergonomics and Human Factors
Open access |
3 Apr 2018 |
32 |