| 1 |
Near-infrared imaging of brain tumors using the Tumor Paint BLZ-100 to achieve near-complete resection of brain tumors
Pramod V. Butte, Adam N. Mamelak, Julia E. Parrish-Novak et al. · Neurosurgical FOCUS
Open access |
Feb 2014 |
125 |
| 2 |
Phase 1 Safety, Pharmacokinetics, and Fluorescence Imaging Study of Tozuleristide (BLZ-100) in Adults With Newly Diagnosed or Recurrent Gliomas
Chirag G. Patil, David Walker, Dennis Michael Miller et al. · Neurosurgery
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5 Apr 2019 |
108 |
| 3 |
Miniproteins as a Powerful Modality in Drug Development
Zachary R. Crook, Natalie Winblade Nairn, James M. Olson · Trends in Biochemical Sciences
ReviewOpen access |
31 Jan 2020 |
97 |
| 4 |
Preclinical Validation of the Utility of BLZ-100 in Providing Fluorescence Contrast for Imaging Spontaneous Solid Tumors
Janean L. Fidel, Katie C. Kennedy, William S. Dernell et al. · Cancer Research
Open access |
14 Oct 2015 |
77 |
| 5 |
Extensive subclonal mutational diversity in human colorectal cancer and its significance
Lawrence A. Loeb, Brendan F. Kohrn, Kaitlyn J. Loubet-Senear et al. · Proceedings of the National Academy of Sciences
Open access |
5 Dec 2019 |
66 |
| 6 |
Error-corrected next generation sequencing – Promises and challenges for genotoxicity and cancer risk assessment
Francesco Marchetti, Renato Cardoso, Connie L. Chen et al. · Mutation Research/Reviews in Mutation Research
Open access |
Jul 2023 |
65 |
| 7 |
Duplex sequencing identifies genomic features that determine susceptibility to benzo(a)pyrene-induced in vivo mutations
Danielle P. M. LeBlanc, Matthew J. Meier, Fang Yin Lo et al. · BMC Genomics
Open access |
28 Jul 2022 |
62 |
| 8 |
Loop-Mediated Isothermal Amplification Detection of SARS-CoV-2 and Myriad Other Applications
Keith J. M. Moore et al. · Journal of Biomolecular Techniques JBT
Open access |
Sep 2021 |
60 |
| 9 |
Precancer in Ulcerative Colitis: The Role of the Field Effect and its Clinical Implications
Kathryn Terese Baker, Jesse J. Salk, Teresa A. Brentnall et al. · Carcinogenesis
Open access |
26 Oct 2017 |
53 |
| 10 |
Nonclinical Profile of BLZ-100, a Tumor-Targeting Fluorescent Imaging Agent
Julia E. Parrish-Novak, Kelly A. Byrnes-Blake, Narine Lalayeva et al. · International Journal of Toxicology
Open access |
Mar 2017 |
49 |
| 11 |
Polymalic acid chlorotoxin nanoconjugate for near-infrared fluorescence guided resection of glioblastoma multiforme
Rameshwar Patil, Anna Galstyan, Tao Sun et al. · Biomaterials
Open access |
23 Mar 2019 |
45 |
| 12 |
Duplex sequencing provides detailed characterization of mutation frequencies and spectra in the bone marrow of MutaMouse males exposed to procarbazine hydrochloride
Annette E. Dodge, Danielle P. M. LeBlanc, Gu Zhou et al. · Archives of Toxicology
Open access |
21 Jun 2023 |
43 |
| 13 |
A potent peptide-steroid conjugate accumulates in cartilage and reverses arthritis without evidence of systemic corticosteroid exposure
Michelle L. Cook Sangar, Emily J. Girard, Gene Hopping et al. · Science Translational Medicine
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4 Mar 2020 |
43 |
| 14 |
Crumbling the Castle: Targeting DNABII Proteins for Collapsing Bacterial Biofilms as a Therapeutic Approach to Treat Disease and Combat Antimicrobial Resistance
James V. Rogers, Veronica L. Hall, Charles C. McOsker · Antibiotics
Open access |
14 Jan 2022 |
42 |
| 15 |
A first-in-human study of BLZ-100 (tozuleristide) demonstrates tolerability and safety in skin cancer patients
Miko Yamada, Dennis Michael Miller, Melinda Lowe et al. · Contemporary Clinical Trials Communications
Open access |
4 Aug 2021 |
40 |
| 16 |
Fluorescence Identification of Head and Neck Squamous Cell Carcinoma and High-Risk Oral Dysplasia With BLZ-100, a Chlorotoxin-Indocyanine Green Conjugate
Fred M. Baik, Stacey J. Hansen, Sue E. Knoblaugh et al. · JAMA Otolaryngology–Head & Neck Surgery
Open access |
19 Feb 2016 |
40 |
| 17 |
Ultra-accurate Duplex Sequencing for the assessment of pretreatment ABL1 kinase domain mutations in Ph+ ALL
Nicholas James Short, Hagop M. Kantarjian, Rashmi Kanagal‐Shamanna et al. · Blood Cancer Journal
Open access |
26 May 2020 |
36 |
| 18 |
Real-time Visualization of Breast Carcinoma in Pathology Specimens From Patients Receiving Fluorescent Tumor-Marking Agent Tozuleristide
Suzanne M. Dintzis, Stacey J. Hansen, Kristi Harrington et al. · Archives of Pathology & Laboratory Medicine
Open access |
14 Dec 2018 |
32 |
| 19 |
CYpHER: catalytic extracellular targeted protein degradation with high potency and durable effect
Zachary R. Crook, Gregory P. Sevilla, P. G. Young et al. · Nature Communications
Open access |
9 Oct 2024 |
28 |
| 20 |
Mitochondrial somatic mutation and selection throughout ageing
Isabel M. Serrano, Misa Hirose, Charles C. Valentine et al. · Nature Ecology & Evolution
Open access |
15 Feb 2024 |
27 |
| 21 |
Liver-on-chip model and application in predictive genotoxicity and mutagenicity of drugs
Benjamin T. Kopp, A. Khawam, K. Di Perna et al. · Mutation Research/Genetic Toxicology and Environmental Mutagenesis
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11 Apr 2024 |
21 |
| 22 |
Image-Guided Tumor Resection
Julia E. Parrish-Novak, Eric C. Holland, James M. Olson · The Cancer Journal
Open access |
May 2015 |
20 |
| 23 |
Assessing the genotoxicity of N‐nitrosodiethylamine with three in vivo endpoints in male Big Blue® transgenic and wild‐type C 57 BL /6 N mice
Shaofei Zhang, Stephanie L. Coffing, William C. Gunther et al. · Environmental and Molecular Mutagenesis
Open access |
Jul 2024 |
18 |
| 24 |
Fluorescence-guided Tumor Visualization Using the Tumor Paint BLZ-100
David S. Kittle, Adam N. Mamelak, Julia E. Parrish-Novak et al. · Cureus
Open access |
22 Sep 2014 |
18 |
| 25 |
Frequencies and spectra of aflatoxin B1-induced mutations in liver genomes of NEIL1-deficient mice as revealed by duplex sequencing
Irina G. Minko, Michael M. Luzadder, Vladimir L. Vartanian et al. · NAR Molecular Medicine
Open access |
Apr 2024 |
11 |
| 26 |
Ex silico engineering of cystine-dense peptides yielding a potent bispecific T cell engager
Zachary R. Crook, Emily J. Girard, Gregory P. Sevilla et al. · Science Translational Medicine
Open access |
18 May 2022 |
11 |
| 27 |
Improving the Assessment of Risk Factors Relevant to Potential Carcinogenicity of Gene Therapies: A Consensus Article
Jan C. Klapwijk et al. · Human Gene Therapy
Open access |
25 Jul 2024 |
8 |
| 28 |
Transferability, Reproducibility and Sensitivity of Mutation Quantification by Duplex Sequencing
Shaofei Zhang et al. · Environmental and Molecular Mutagenesis
Open access |
30 Jun 2025 |
6 |
| 29 |
Immune infiltrate populations within distinct tumor immune microenvironments predictive of immune checkpoint treatment outcome
Brian Z. Ring, Catherine T. Cronister, Huijun Z. Ring et al. · Scientific Reports
Open access |
24 Jan 2025 |
6 |
| 30 |
Duplex sequencing identifies unique characteristics of ENU-induced mutations in male mouse germ cells
Danielle P. M. LeBlanc, Gu Zhou, Andrew Williams et al. · Biology of Reproduction
Open access |
12 Feb 2025 |
5 |
| 31 |
Mapping the Escherichia coli DnaA-binding landscape reveals a preference for binding pairs of closely spaced DNA sites
Anne M. Stringer, Devon M. Fitzgerald, Joseph T. Wade · Microbiology
Open access |
16 Jul 2024 |
5 |
| 32 |
Phase 1 and expanded imaging study of tozuleristide in patients with pediatric primary central nervous system tumors
Amy Lee, Bonnie Cole, Jeffrey G. Ojemann et al. · Journal of Neurosurgery Pediatrics
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30 Aug 2025 |
4 |
| 33 |
ACTR-49. PHASE 1 SAFETY STUDY OF BLZ-100 FOR FLUORESCENCE-GUIDED RESECTION OF GLIOMA IN ADULT SUBJECTS
Dennis Michael Miller, Chirag G. Patil, David Walker et al. · Neuro-Oncology
Open access |
Nov 2016 |
4 |
| 34 |
Chemically induced skin tumors arise from long-lived stem cells of the upper hair follicle
Eve E. Kandyba, Arnaud Jabouille, Ferriol Calvet et al. · Science
Open access |
11 Jun 2026 |
2 |
| 35 |
US immigration order strikes against biotech
Jeremy M. Levin et al. · Nature Biotechnology
192 authors |
Mar 2017 |
2 |
| 36 |
svCapture: Efficient and specific detection of very low frequency structural variant junctions by error-minimized capture sequencing
Thomas E. Wilson, Samreen I. Ahmed, Jake Higgins et al. · bioRxiv (Cold Spring Harbor Laboratory)
PreprintOpen access |
7 Jul 2022 |
1 |
| 37 |
ATNT-16PHASE 1 DOSE ESCALATION AND EXPANSION SAFETY STUDY OF BLZ-100 FOR FLUORESCENCE GUIDED RESECTION OF GLIOMA IN ADULTS
Chirag G. Patil, David K. Walker, Pramod V. Butte et al. · Neuro-Oncology
Open access |
Nov 2015 |
1 |
| 38 |
High-grade serous ovarian cancer is associated with increased TP53 mutation burden in uterine lavage
Nicole Heinzl et al. · npj Precision Oncology
Open access |
29 Aug 2026 |
0 |
| 39 |
Canvas fluorescence imaging system characterization for intraoperative visualization of cancer cells with tozuleristide (BLZ-100) for a randomized, multi-center, phase 2/3 pediatric CNS tumor trial
David S. Kittle, Kristi Harrington, Julie M. Novak et al.
Conference paper |
19 Mar 2025 |
0 |
| 40 |
Biotech leaders call for free press
Ron Cohen et al. · Nature Biotechnology
170 authors |
Oct 2018 |
0 |
| 41 |
Molecular imaging based skin cancer diagnostic platform
Miko Yamada, Dennis Michael Miller, Julia E. Parrish-Novak et al. · Journal of Dermatological Science
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29 Sep 2016 |
0 |
| 42 |
Fluorescence-guided tumor visualization using a custom designed NIR attachment to a surgical microscope for high sensitivity imaging (Conference Presentation)
David S. Kittle, Chirag G. Patil, Adam N. Mamelak et al.
Conference paper |
26 Apr 2016 |
0 |
| 43 |
Clinical development of BLZ-100 for real-time optical imaging of tumors during resection
Heather L. Franklin, Dennis Michael Miller, Teresa Hedges et al. · Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE
Conference paper |
4 Mar 2016 |
0 |