Institution · Boston Biomedical Research Institute
Most cited papers from Boston Biomedical Research Institute
What are the most cited papers from Boston Biomedical Research Institute?
The most cited paper from Boston Biomedical Research Institute is "Extracellular DNA traps promote thrombosis" (Tobias A. Fuchs, Alexander G. Brill, Daniel Duerschmied et al., 2010), with 2,500 citations. Next come "A mutation in Orai1 causes immune deficiency by abrogating CRAC channel function" (2,298) and "Dynasore, a Cell-Permeable Inhibitor of Dynamin" (2,085).
Showing 50 of 60 papers. Every paper with more than 438 citations is listed.
| # | Paper | ||
|---|---|---|---|
| 1 | Extracellular DNA traps promote thrombosis Tobias A. Fuchs, Alexander G. Brill, Daniel Duerschmied et al. · Proceedings of the National Academy of Sciences | 23 Aug 2010 | 2,500 |
| 2 | A mutation in Orai1 causes immune deficiency by abrogating CRAC channel function Stefan Feske, Yousang Gwack, Murali Prakriya et al. · Nature | 2 Apr 2006 | 2,298 |
| 3 | Dynasore, a Cell-Permeable Inhibitor of Dynamin Eric Macia, Marcelo Ehrlich, Ramiro Massol et al. · Developmental Cell | Jun 2006 | 2,085 |
| 4 | Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes Eleftheria Zeggini et al. · Nature Genetics | 30 Mar 2008 | 1,880 |
| 5 | T-cell priming by dendritic cells in lymph nodes occurs in three distinct phases Thorsten R. Mempel, Sarah Emily Henrickson, Ulrich H. von Andrian · Nature | 2004 | 1,726 |
| 6 | Mutations in prion-like domains in hnRNPA2B1 and hnRNPA1 cause multisystem proteinopathy and ALS Hong Joo Kim et al. · Nature | Mar 2013 | 1,535 |
| 7 | Regulation of the Germinal Center Response by MicroRNA-155 To‐Ha Thai, Dinis Pedro Calado, Stefano S Casola et al. · Science | 26 Apr 2007 | 1,486 |
| 8 | Signalling through the lipid products of phosphoinositide-3-OH kinase Alex Toker, Lewis C. Cantley · Nature | 12 Jun 1997 | 1,318 |
| 9 | Transvascular delivery of small interfering RNA to the central nervous system Priti Kumar, Haoquan Wu, Jodi L. McBride et al. · Nature | 17 Jun 2007 | 1,247 |
| 10 | MiR-150 Controls B Cell Differentiation by Targeting the Transcription Factor c-Myb Changchun Xiao, Dinis Pedro Calado, Gunther R. Galler et al. · Cell | Oct 2007 | 1,045 |
| 11 | Reversal of Histone Lysine Trimethylation by the JMJD2 Family of Histone Demethylases Johnathan R. Whetstine, Amanda C. Nottke, Fei Lan et al. · Cell | 7 Apr 2006 | 1,043 |
| 12 | A Systematic Survey Identifies Prions and Illuminates Sequence Features of Prionogenic Proteins Simon Alberti, Randal Halfmann, Oliver D. King et al. · Cell | Apr 2009 | 1,018 |
| 13 | Generation of Gut-Homing IgA-Secreting B Cells by Intestinal Dendritic Cells J. Rodrigo Mora, Makoto Iwata, Bertus Eksteen et al. · Science | 16 Nov 2006 | 1,009 |
| 14 | Cellular Defenses against Unfolded Proteins Michael Y. Sherman, Alfred L. Goldberg · Neuron | 2001 | 991 |
| 15 | T cell– and B cell–independent adaptive immunity mediated by natural killer cells Jacqueline G. O’Leary, Mahmoud Goodarzi, Danielle L. Drayton et al. · Nature Immunology | 16 Apr 2006 | 916 |
| 16 | Endocytosis by Random Initiation and Stabilization of Clathrin-Coated Pits Marcelo Ehrlich, Werner Boll, Antoine M. van Oijen et al. · Cell | Sep 2004 | 907 |
| 17 | The Rat Grimace Scale: A Partially Automated Method for Quantifying Pain in the Laboratory Rat via Facial Expressions Susana G Sotocina, Robert E. Sorge, Austin Zaloum et al. · Molecular Pain | 2011 | 903 |
| 18 | Cancers predispose neutrophils to release extracellular DNA traps that contribute to cancer-associated thrombosis Mélanie Demers, Daniela S. Krause, Daphne Schatzberg et al. · Proceedings of the National Academy of Sciences | 23 Jul 2012 | 893 |
| 19 | A dual-kinase mechanism for Wnt co-receptor phosphorylation and activation Xin Zeng, Keiko Tamai, Bradley W. Doble et al. · Nature | Dec 2005 | 866 |
| 20 | Structural basis for allostery in integrins and binding to fibrinogen-mimetic therapeutics Tsan Sam Xiao, Junichi Takagi, Barry S. Coller et al. · Nature | 19 Sep 2004 | 856 |
| 21 | Zero-length crosslinking procedure with the use of active esters Zenon Grabarek, John S. Gergely · Analytical Biochemistry | Feb 1990 | 826 |
| 22 | Interleukin-2 and Inflammation Induce Distinct Transcriptional Programs that Promote the Differentiation of Effector Cytolytic T Cells Matthew E. Pipkin, Jilian A. Sacks, Fernando Cruz‐Guilloty et al. · Immunity | 2010 | 790 |
| 23 | The Chaperone Function of hsp70 Is Required for Protection against Stress-Induced Apoptosis Dick D. Mosser, Antoine W. Caron, Lucie Bourget et al. · Molecular and Cellular Biology | 15 Oct 2000 | 741 |
| 24 | Mechanisms of smooth muscle contraction Arie Horowitz, Constance B. Menice, Régent Laporte et al. · Physiological Reviews | Oct 1996 | 741 |
| 25 | WEAP21—A Demand-, Priority-, and Preference-Driven Water Planning Model David N Yates, Jack Sieber, David Purkey et al. · Water International | Dec 2005 | 733 |
| 26 | Sarcopenia Definition: The Position Statements of the Sarcopenia Definition and Outcomes Consortium Shalender Bhasin et al. · Journal of the American Geriatrics Society | 9 Mar 2020 | 718 |
| 27 | Accelerated death of retinal microvascular cells in human and experimental diabetic retinopathy. Masakazu Mizutani, Timothy S. Kern, Mara Lorenzi · Journal of Clinical Investigation | 15 Jun 1996 | 710 |
| 28 | The tip of the iceberg: RNA-binding proteins with prion-like domains in neurodegenerative disease Oliver D. King, Aaron D. Gitler, James Shorter · Brain Research | 28 Jan 2012 | 679 |
| 29 | SirT2 is a histone deacetylase with preference for histone H4 Lys 16 during mitosis Alejandro Vaquero, Michael B. Scher, Dong Hoon Lee et al. · Genes & Development | 28 Apr 2006 | 672 |
| 30 | Mechanical compression drives cancer cells toward invasive phenotype Janet M. Tse, Gang Cheng, James Alexander Tyrrell et al. · Proceedings of the National Academy of Sciences | 27 Dec 2011 | 653 |
| 31 | MEK1 mutations confer resistance to MEK and B-RAF inhibition Caroline M. Emery, Krishna G. Vijayendran, Marie C. Zipser et al. · Proceedings of the National Academy of Sciences | 13 Nov 2009 | 642 |
| 32 | Significance of impulse activity in the transformation of skeletal muscle type Stanley Salmons, Frank A. Sreter · Nature | 2 Sep 1976 | 637 |
| 33 | Activation of Phosphoinositide 3-OH Kinase by the α6β4 Integrin Promotes Carcinoma Invasion Leslie M Shaw, Isaac Rabinovitz, Helen H.-F Wang et al. · Cell | Dec 1997 | 617 |
| 34 | Regulation of protein kinase C ζ by PI 3-kinase and PDK-1 Margaret M. Chou, Weimin Hou, Joanne E. Johnson et al. · Current Biology | Sep 1998 | 616 |
| 35 | Single-column purification of free recombinant proteins using a self-cleavable affinity tag derived from a protein splicing element Shaorong Chong, Fana B. Mersha, Donald G. Comb et al. · Gene | Jun 1997 | 609 |
| 36 | Reconstitution of Troponin Activity from Three Protein Components Marion L. Greaser, John S. Gergely · Journal of Biological Chemistry | Jul 1971 | 606 |
| 37 | Dual functions for the endoplasmic reticulum calcium sensors STIM1 and STIM2 in T cell activation and tolerance Masatsugu Oh‐hora, Megumi Yamashita, Patrick G. Hogan et al. · Nature Immunology | 9 Mar 2008 | 599 |
| 38 | MECHANISM AND CONTROL OF V(D)J RECOMBINATION AT THE IMMUNOGLOBULIN HEAVY CHAIN LOCUS David Heredero Jung, Cosmas C. Giallourakis, Raúl Mostoslavsky et al. · Annual Review of Immunology | 16 Jan 2006 | 585 |
| 39 | The Relationship Between Depressive Symptoms and Male Erectile Dysfunction André Brandão de Araújo, Richard Durante, Henry A. Feldman et al. · Psychosomatic Medicine | 1998 | 580 |
| 40 | Platelets in Inflammation and Thrombosis Denisa D. Wagner, Peter C. Burger · Arteriosclerosis Thrombosis and Vascular Biology | 22 Sep 2003 | 568 |
| 41 | Pharmacological perturbation of CDK9 using selective CDK9 inhibition or degradation Calla M Olson, Baishan Jiang, Michael A. Erb et al. · Nature Chemical Biology | 18 Dec 2017 | 565 |
| 42 | γ-H2AX Dephosphorylation by Protein Phosphatase 2A Facilitates DNA Double-Strand Break Repair Dipanjan Chowdhury, Michael‐Christopher Keogh, Haruhiko Ishii et al. · Molecular Cell | 29 Nov 2005 | 545 |
| 43 | Transcription factors T-bet and Runx3 cooperate to activate Ifng and silence Il4 in T helper type 1 cells Ivana M. Djuretic, Ditsa Levanon, Varda Negreanu et al. · Nature Immunology | 31 Dec 2006 | 537 |
| 44 | Hydrogel scaffolds for tissue engineering: the importance of polymer choice Christopher D. Spicer · Polymer Chemistry | 25 Sep 2019 | 536 |
| 45 | The Crystal Structure of Uncomplexed Actin in the ADP State Ludovic R. Otterbein, Philip Graceffa, Roberto Domínguez · Science | 27 Jul 2001 | 536 |
| 46 | Boundary analysis in sedimentation transport experiments: A procedure for obtaining sedimentation coefficient distributions using the time derivative of the concentration profile Walter F. Stafford · Analytical Biochemistry | Jun 1992 | 524 |
| 47 | IL-10–producing and naturally occurring CD4+ Tregs: limiting collateral damage Anne O’Garra, Pedro L. Vieira, Paulo Rufino Paulino Vieira et al. · Journal of Clinical Investigation | 15 Nov 2004 | 523 |
| 48 | Akt/Protein Kinase B Is Regulated by Autophosphorylation at the Hypothetical PDK-2 Site Alex Toker, Alexandra C. Newton · Journal of Biological Chemistry | Mar 2000 | 518 |
| 49 | Hsp70 Prevents Activation of Stress Kinases Vladimir L. Gabai, Anatoli B. Meriin, Dick D. Mosser et al. · Journal of Biological Chemistry | Jul 1997 | 511 |
| 50 | Regulatory T Cells Reversibly Suppress Cytotoxic T Cell Function Independent of Effector Differentiation Thorsten R. Mempel, Mikaël J. Pittet, Khashayarsha Khazaie et al. · Immunity | Jul 2006 | 495 |
Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.