Institution · Broad Center
Most cited papers from Broad Center
What are the most cited papers from Broad Center?
The most cited paper from Broad Center is "Neurotoxic reactive astrocytes are induced by activated microglia" (Shane A. Liddelow et al., 2017), with 8,364 citations. Next come "Molecular mechanisms of epithelial–mesenchymal transition" (8,337) and "Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)" (6,023).
Showing 50 of 60 papers. Every paper with more than 677 citations is listed.
| # | Paper | ||
|---|---|---|---|
| 1 | Neurotoxic reactive astrocytes are induced by activated microglia Shane A. Liddelow et al. · Nature | 2017 | 8,364 |
| 2 | Molecular mechanisms of epithelial–mesenchymal transition Samy Lamouille, Jian Xu, Rik Derynck · Nature Reviews Molecular Cell Biology | 21 Feb 2014 | 8,337 |
| 3 | Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) Daniel J. Klionsky et al. · Autophagy | 2 Jan 2016 | 6,023 |
| 4 | The extracellular matrix at a glance Christian Frantz, Kathleen M. Stewart, Valerie Marie Weaver · Journal of Cell Science | Dec 2010 | 4,397 |
| 5 | Matrix Crosslinking Forces Tumor Progression by Enhancing Integrin Signaling Kandice R. Levental, Hongmei Yu, Laura Kass et al. · Cell | Nov 2009 | 4,155 |
| 6 | The ground state of embryonic stem cell self-renewal Qi‐Long Ying, Jason P. Wray, Jennifer Nichols et al. · Nature | May 2008 | 3,583 |
| 7 | Large-Scale Exome Sequencing Study Implicates Both Developmental and Functional Changes in the Neurobiology of Autism F. Kyle Satterstrom et al. · Cell | 23 Jan 2020 | 2,534 |
| 8 | The Glial Nature of Embryonic and Adult Neural Stem Cells Arnold R. Kriegstein, Arturo Álvarez-Buylla · Annual Review of Neuroscience | Jun 2009 | 2,512 |
| 9 | The Human Cell Atlas Aviv Regev et al. · eLife | 5 Dec 2017 | 2,441 |
| 10 | The extracellular matrix modulates the hallmarks of cancer Michael W. Pickup, Janna K. Mouw, Valerie Marie Weaver · EMBO Reports | 8 Nov 2014 | 2,051 |
| 11 | Extracellular matrix assembly: a multiscale deconstruction Janna K. Mouw, Guanqing Ou, Valerie Marie Weaver · Nature Reviews Molecular Cell Biology | 5 Nov 2014 | 1,542 |
| 12 | Human hippocampal neurogenesis drops sharply in children to undetectable levels in adults Shawn F. Sorrells, Mercedes F. Paredes, Arantxa Cebrián‐Silla et al. · Nature | Mar 2018 | 1,449 |
| 13 | Neurogenic radial glia in the outer subventricular zone of human neocortex David V. Hansen, Jan H. Lui, Philip R. L. Parker et al. · Nature | 15 Feb 2010 | 1,421 |
| 14 | Assembly of functionally integrated human forebrain spheroids Fikri Birey, Jimena Andersen, Christopher D. Makinson et al. · Nature | 25 Apr 2017 | 1,394 |
| 15 | Development and Evolution of the Human Neocortex Jan H. Lui, David V. Hansen, Arnold R. Kriegstein · Cell | Jul 2011 | 1,384 |
| 16 | Suppression of Exosomal PD-L1 Induces Systemic Anti-tumor Immunity and Memory Mauro Poggio, Tianyi Hu, Chien-Chun Steven Pai et al. · Cell | Apr 2019 | 1,377 |
| 17 | The Xist lncRNA interacts directly with SHARP to silence transcription through HDAC3 Colleen A. McHugh, Chun‐Kan Chen, Amy Y. Chow et al. · Nature | 24 Apr 2015 | 1,249 |
| 18 | Individual brain organoids reproducibly form cell diversity of the human cerebral cortex Silvia Velasco, Amanda J. Kedaigle, Sean Simmons et al. · Nature | Jun 2019 | 1,149 |
| 19 | Young blood reverses age-related impairments in cognitive function and synaptic plasticity in mice Saul Villeda, Kristopher E. Plambeck, Jinte Middeldorp et al. · Nature Medicine | 4 May 2014 | 1,120 |
| 20 | Human breast cancer invasion and aggression correlates with ECM stiffening and immune cell infiltration Irene Acerbi, Luke Cassereau, Ivory S. Dean et al. · Integrative Biology | May 2015 | 1,104 |
| 21 | Chromatin-state discovery and genome annotation with ChromHMM Jason Ernst, Manolis Kellis · Nature Protocols | 9 Nov 2017 | 1,086 |
| 22 | Spatiotemporal gene expression trajectories reveal developmental hierarchies of the human cortex Tomasz Jan Nowakowski, Aparna Bhaduri, Alex A. Pollen et al. · Science | 7 Dec 2017 | 1,065 |
| 23 | Single-cell genomics identifies cell type–specific molecular changes in autism Dmitry Velmeshev, Lucas Schirmer, Diane Jung et al. · Science | 16 May 2019 | 1,045 |
| 24 | Induced Pluripotent Stem Cells and Embryonic Stem Cells Are Distinguished by Gene Expression Signatures Mark H. Chin et al. · Cell stem cell | Jul 2009 | 1,044 |
| 25 | Generation of human induced pluripotent stem cells from dermal fibroblasts William E. Lowry, Laura Richter, Robin Yachechko et al. · Proceedings of the National Academy of Sciences | 15 Feb 2008 | 1,037 |
| 26 | Low-coverage single-cell mRNA sequencing reveals cellular heterogeneity and activated signaling pathways in developing cerebral cortex Alex A. Pollen et al. · Nature Biotechnology | 3 Aug 2014 | 1,022 |
| 27 | Dispersive Fourier transformation for fast continuous single-shot measurements Keisuke Goda, Bahram Jalali · Nature Photonics | 31 Jan 2013 | 1,011 |
| 28 | Balancing forces: architectural control of mechanotransduction Christopher C. DuFort, Matthew J. Paszek, Valerie Marie Weaver · Nature Reviews Molecular Cell Biology | 21 Apr 2011 | 1,001 |
| 29 | Organoids Zixuan Zhao, Xinyi Chen, Anna M. Dowbaj et al. · Nature Reviews Methods Primers | Dec 2022 | 994 |
| 30 | Non-CG methylation patterns shape the epigenetic landscape in Arabidopsis Hume Stroud, Truman J. Do, Jiamu Du et al. · Nature Structural & Molecular Biology | 15 Dec 2013 | 972 |
| 31 | microRNA Regulation of Inflammatory Responses Ryan M. O’Connell, Dinesh S. Rao, David Baltimore · Annual Review of Immunology | 26 Mar 2012 | 970 |
| 32 | Comprehensive Analysis of Silencing Mutants Reveals Complex Regulation of the Arabidopsis Methylome Hume Stroud, Max Greenberg, Suhua Feng et al. · Cell | 2013 | 961 |
| 33 | Molecular Identity of Human Outer Radial Glia during Cortical Development Alex A. Pollen, Tomasz Jan Nowakowski, Jiadong Chen et al. · Cell | Sep 2015 | 956 |
| 34 | Autophagy maintains the metabolism and function of young and old stem cells Theodore T. Ho, Matthew R. Warr, Emmalee R. Adelman et al. · Nature | 27 Feb 2017 | 927 |
| 35 | Dynamic interplay between the collagen scaffold and tumor evolution Mikala Egeblad, Morten Grønbech Rasch, Valerie Marie Weaver · Current Opinion in Cell Biology | 7 Sep 2010 | 912 |
| 36 | Vitamin C induces Tet-dependent DNA demethylation and a blastocyst-like state in ES cells Kathryn Blaschke, Kevin T. Ebata, Mohammad Mahdi Karimi et al. · Nature | 28 Jun 2013 | 901 |
| 37 | Corridors of migrating neurons in the human brain and their decline during infancy Nader Sanai, Thuhien M. Nguyen, Rebecca A. Ihrie et al. · Nature | 28 Sep 2011 | 862 |
| 38 | The use of brain organoids to investigate neural development and disease Elizabeth Di Lullo, Arnold R. Kriegstein · Nature reviews. Neuroscience | 7 Sep 2017 | 823 |
| 39 | Specificity, versatility, and control of TGF-β family signaling Rik Derynck, Erine H. Budi · Science Signaling | 26 Feb 2019 | 822 |
| 40 | Proliferative Neural Stem Cells Have High Endogenous ROS Levels that Regulate Self-Renewal and Neurogenesis in a PI3K/Akt-Dependant Manner Janel E. Le Belle, Nicolas M. Orozco, Andres A. Paucar et al. · Cell stem cell | 2011 | 819 |
| 41 | Pan-cancer analysis of the extent and consequences of intratumor heterogeneity Noemi Andor, Trevor A. Graham, Marnix Jansen et al. · Nature Medicine | 30 Nov 2015 | 818 |
| 42 | CRISPRi-based genome-scale identification of functional long noncoding RNA loci in human cells Siyuan John Liu, Max A. Horlbeck, Seung Woo Cho et al. · Science | 15 Dec 2016 | 799 |
| 43 | TGF-β signaling and epithelial–mesenchymal transition in cancer progression Yoko Katsuno, Samy Lamouille, Rik Derynck · Current Opinion in Oncology | 28 Nov 2012 | 798 |
| 44 | Hydrodynamic stretching of single cells for large population mechanical phenotyping Daniel R. Gossett, Henry T. K. Tse, Serena A. Lee et al. · Proceedings of the National Academy of Sciences | 30 Apr 2012 | 793 |
| 45 | Identification and Classification of Chromosomal Aberrations in Human Induced Pluripotent Stem Cells Yoav Mayshar, Uri Ben‐David, Neta Lavon et al. · Cell stem cell | Oct 2010 | 774 |
| 46 | Reactive oxygen species prime Drosophila haematopoietic progenitors for differentiation Edward Owusu-Ansah, Utpal K. Banerjee · Nature | Sep 2009 | 750 |
| 47 | Functionally Distinct Subsets of Lineage-Biased Multipotent Progenitors Control Blood Production in Normal and Regenerative Conditions Eric Martin Pietras, Damien Reynaud, Yoon-A Kang et al. · Cell stem cell | 18 Jun 2015 | 748 |
| 48 | Fibrosis and cancer: A strained relationship Bram Piersma, Mary-Kate Hayward, Valerie Marie Weaver · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer | 9 Mar 2020 | 735 |
| 49 | Developmental genetics of vertebrate glial–cell specification David H. Rowitch, Arnold R. Kriegstein · Nature | 9 Nov 2010 | 730 |
| 50 | Long noncoding RNAs in cancer metastasis Siyuan John Liu, Ha X. Dang, Daniel A. Lim et al. · Nature reviews. Cancer | 5 May 2021 | 723 |
Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.