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Most cited papers from Brown Foundation

What are the most cited papers from Brown Foundation?

The most cited paper from Brown Foundation is "An RNA-Sequencing Transcriptome and Splicing Database of Glia, Neurons, and Vascular Cells of the Cerebral Cortex" (Ye Zhang, Kenian Chen, Steven A. Sloan et al., 2014), with 5,474 citations. Next come "A framework for advancing our understanding of cancer-associated fibroblasts" (3,962) and "Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing" (3,277).

Showing 50 of 60 papers. Every paper with more than 347 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 An RNA-Sequencing Transcriptome and Splicing Database of Glia, Neurons, and Vascular Cells of the Cerebral Cortex Ye Zhang, Kenian Chen, Steven A. Sloan et al. · Journal of Neuroscience Open access 3 Sep 2014 5,474
2 A framework for advancing our understanding of cancer-associated fibroblasts Erik A. Sahai et al. · Nature reviews. Cancer ReviewOpen access 24 Jan 2020 3,962
3 Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing Brian W. Kunkle et al. · Nature Genetics ReviewOpen access469 authors 28 Feb 2019 3,277
4 Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition) 1 Daniel J. Klionsky et al. · Autophagy Open access2,930 authors 2 Jan 2021 2,743
5 Spike mutation D614G alters SARS-CoV-2 fitness Jessica A. Plante et al. · Nature Open access 26 Oct 2020 1,770
6 Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes Rainer Malik et al. · Nature Genetics Open access428 authors 12 Mar 2018 1,753
7 Mesenchymal Stem Cells: Revisiting History, Concepts, and Assays Paolo Bianco, Pamela Gehron Robey, Paul J. Simmons · Cell stem cell Open access Apr 2008 1,633
8 Challenges and Key Considerations of the Enhanced Permeability and Retention Effect for Nanomedicine Drug Delivery in Oncology Uma Prabhakar, Hiroshi Maeda, Rakesh K. Jain et al. · Cancer Research Open access 19 Feb 2013 1,488
9 Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries Mary Furlan Feitosa et al. · PLoS ONE Open access273 authors 18 Jun 2018 1,174
10 Genetic analyses of diverse populations improves discovery for complex traits Genevieve L. Wojcik et al. · Nature Open access Jun 2019 1,166
11 Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease Rebecca C. Sims et al. · Nature Genetics Open access450 authors 17 Jul 2017 1,122
12 The power of genetic diversity in genome-wide association studies of lipids Sarah E. Graham et al. · Nature Open access527 authors 9 Dec 2021 1,099
13 Food sources of nitrates and nitrites: the physiologic context for potential health benefits Norman G. Hord, Yaoping Tang, Nathan S. Bryan · American Journal of Clinical Nutrition Open access 14 May 2009 1,071
14 R-spondins function as ligands of the orphan receptors LGR4 and LGR5 to regulate Wnt/β-catenin signaling Kendra S. Carmon, Xing Wen Gong, Qiushi Lin et al. · Proceedings of the National Academy of Sciences Open access 21 Jun 2011 868
15 Polygenic Prediction of Weight and Obesity Trajectories from Birth to Adulthood Amit V. Khera, Mark D. Chaffin, Kaitlin Hazel Wade et al. · Cell Open access Apr 2019 852
16 TREM2 Is a Receptor for β-Amyloid that Mediates Microglial Function Yingjun Zhao, Xilin Wu, Xiaoguang Li et al. · Neuron Open access Mar 2018 828
17 Loss of furin cleavage site attenuates SARS-CoV-2 pathogenesis Bryan A. Johnson et al. · Nature Open access 25 Jan 2021 790
18 Antibody-drug conjugates: recent advances in conjugation and linker chemistries Kyoji Tsuchikama, Zhiqiang An · Protein & Cell Open access 14 Oct 2016 789
19 Inherited causes of clonal haematopoiesis in 97,691 whole genomes Alexander G. Bick et al. · Nature Open access414 authors 14 Oct 2020 766
20 PAT proteins, an ancient family of lipid droplet proteins that regulate cellular lipid stores Perry E. Bickel, John T. Tansey, Michael Andreas Welte · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids Open access 17 Apr 2009 675
21 Mesoporous silicon particles as a multistage delivery system for imaging and therapeutic applications Ennio Tasciotti, Xuewu Liu, Rohan C. Bhavane et al. · Nature Nanotechnology Mar 2008 674
22 Stroke genetics informs drug discovery and risk prediction across ancestries Aniket Mishra et al. · Nature Open access592 authors 30 Sep 2022 637
23 Nanoparticle‐induced platelet aggregation and vascular thrombosis Anna S. Radomski, Paul Jurasz, David Alonso‐Escolano et al. · British Journal of Pharmacology Open access 12 Sep 2005 634
24 Exploring the next generation of antibody–drug conjugates Kyoji Tsuchikama, Yasuaki Anami, Summer Y.Y. Ha et al. · Nature Reviews Clinical Oncology Review 8 Jan 2024 627
25 SUMO-Specific Protease 1 Is Essential for Stabilization of HIF1α during Hypoxia Jinke Cheng, Xunlei Kang, Sui Zhang et al. · Cell Open access Nov 2007 621
26 Nitrate and nitrite in biology, nutrition and therapeutics Jon O. Lundberg et al. · Nature Chemical Biology Open access 13 Nov 2009 618
27 Intravascular Delivery of Particulate Systems: Does Geometry Really Matter? Paolo Decuzzi, Renata Pasqualini, Wadih Arap et al. · Pharmaceutical Research Open access 19 Aug 2008 610
28 Differentiation of Human Pluripotent Stem Cells into Functional Lung Alveolar Epithelial Cells Anjali Anne Jacob et al. · Cell stem cell Open access 29 Sep 2017 608
29 In silico prediction of splice-altering single nucleotide variants in the human genome Xueqiu Jian, Eric Boerwinkle, Xiaoming Liu · Nucleic Acids Research Open access 21 Nov 2014 582
30 The N501Y spike substitution enhances SARS-CoV-2 infection and transmission Yang Liu, Jianying Liu, Kenneth S. Plante et al. · Nature Open access 24 Nov 2021 569
31 Seven challenges for nanomedicine Wendy R. Sanhai, Jason H. Sakamoto, Richard Canady et al. · Nature Nanotechnology May 2008 539
32 Genetic diversity fuels gene discovery for tobacco and alcohol use Gretchen Saunders et al. · Nature Open access218 authors 7 Dec 2022 532
33 Minireview: Lipid Droplets in Lipogenesis and Lipolysis Nicole A. Ducharme, Perry E. Bickel · Endocrinology Open access 17 Jan 2008 522
34 Ubiquitin-like proteins: new wines in new bottles Edward T.H. Yeh, Limin Gong, Tetsu Kamitani · Gene May 2000 468
35 Genomewide Association Studies of Stroke M. Arfan Ikram et al. · New England Journal of Medicine Open access 15 Apr 2009 463
36 Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders Symen Ligthart et al. · The American Journal of Human Genetics Open access349 authors Nov 2018 461
37 Impact of common genetic determinants of Hemoglobin A1c on type 2 diabetes risk and diagnosis in ancestrally diverse populations: A transethnic genome-wide meta-analysis Eleanor Wheeler et al. · PLoS Medicine Open access216 authors 12 Sep 2017 450
38 Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure LifeLines Cohort Study et al. · Nature Genetics Open access226 authors 11 Sep 2011 447
39 Biologically Active Secondary Metabolites from the Fungi Gerald F. Bills, James B. Gloer · Microbiology Spectrum 4 Nov 2016 444
40 Heterocyclic Schiff base transition metal complexes in antimicrobial and anticancer chemotherapy Manzoor Ahmad Malik, Ovas Ahmad Dar, Parveez Gull et al. · MedChemComm Open access 6 Dec 2017 437
41 Cancer as a Matter of Fat: The Crosstalk between Adipose Tissue and Tumors Ernst R. Lengyel, Liza Makowski, John DiGiovanni et al. · Trends in cancer ReviewOpen access 6 Apr 2018 435
42 An international effort towards developing standards for best practices in analysis, interpretation and reporting of clinical genome sequencing results in the CLARITY Challenge Catherine A. Brownstein et al. · Genome biology Open access198 authors 25 Mar 2014 433
43 Huntingtin functions as a scaffold for selective macroautophagy Yan‐Ning Rui, Zhen Xu, Bindi Patel et al. · Nature Cell Biology Open access 16 Feb 2015 427
44 Nitric Oxide and Cyclic GMP in Cell Signaling and Drug Development Ferid Murad · New England Journal of Medicine 8 Nov 2006 423
45 Tumour DDR1 promotes collagen fibre alignment to instigate immune exclusion Xiujie Sun et al. · Nature Open access 3 Nov 2021 421
46 Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function María Soler Artigas et al. · Nature Genetics Open access169 authors 25 Sep 2011 417
47 Genetic contributions to variation in general cognitive function: a meta-analysis of genome-wide association studies in the CHARGE consortium (N=53 949) Gail Davies et al. · Molecular Psychiatry ReviewOpen access129 authors Feb 2015 413
48 Delta spike P681R mutation enhances SARS-CoV-2 fitness over Alpha variant Yang Liu, Jianying Liu, Bryan A. Johnson et al. · Cell Reports Open access 29 Apr 2022 398
49 Association of Body Mass Index with DNA Methylation and Gene Expression in Blood Cells and Relations to Cardiometabolic Disease: A Mendelian Randomization Approach Michael Mendelson et al. · PLoS Medicine Open access 17 Jan 2017 398
50 Land‐use change affects water recycling in Brazil's last agricultural frontier Stephanie A. Spera, Gillian L. Galford, Michael T. Coe et al. · Global Change Biology 30 Mar 2016 398

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.