Most cited papers from Calico Life Sciences

Calico Life Sciences

What are the most cited papers from Calico Life Sciences?

The most cited paper from Calico Life Sciences is "A molecular cell atlas of the human lung from single-cell RNA sequencing" (Kyle J. Travaglini, Ahmad N. Nabhan, Lolita Penland et al., 2020), with 1,890 citations. Next come "Plasma proteomic associations with genetics and health in the UK Biobank" (1,716) and "Effective gene expression prediction from sequence by integrating long-range interactions" (1,419).

Published TypeFieldAccessCitations

Showing 50 of 60 papers. Every paper with more than 94 citations is listed.

Most cited papers, sortable by citations and release date
#	Paper
1	A molecular cell atlas of the human lung from single-cell RNA sequencing Kyle J. Travaglini, Ahmad N. Nabhan, Lolita Penland et al. · Nature Open access	18 Nov 2020	1,890
2	Plasma proteomic associations with genetics and health in the UK Biobank Benjamin B. Sun et al. · Nature Open access	4 Oct 2023	1,716
3	Effective gene expression prediction from sequence by integrating long-range interactions Žiga Avsec, Vikram Agarwal, Daniel Visentin et al. · Nature Methods Open access	Oct 2021	1,419
4	Physiological blood–brain transport is impaired with age by a shift in transcytosis Andrew C. Yang et al. · Nature Open access	Jul 2020	496
5	Exercise plasma boosts memory and dampens brain inflammation via clusterin Zurine D. Miguel et al. · Nature Open access	8 Dec 2021	440
6	Evidence for hormonal control of heart regenerative capacity during endothermy acquisition Kentaro Hirose et al. · Science Open access	7 Mar 2019	386
7	How to build the virtual cell with artificial intelligence: Priorities and opportunities Charlotte Bunne et al. · Cell Open access	Dec 2024	383
8	Dynamic Ligand Discrimination in the Notch Signaling Pathway Nagarajan Nandagopal, Leah A. Santat, Lauren LeBon et al. · Cell Open access	Feb 2018	360
9	Predicting 3D genome folding from DNA sequence with Akita Geoffrey Fudenberg, David R. Kelley, Katherine S. Pollard · Nature Methods Open access	12 Oct 2020	342
10	Extrachromosomal circular DNA is common in yeast Henrik Devitt Møller, Lance Parsons, Tue S. Jørgensen et al. · Proceedings of the National Academy of Sciences Open access	2 Jun 2015	335
11	The immunoregulatory landscape of human tuberculosis granulomas Erin McCaffrey et al. · Nature Immunology Open access	20 Jan 2022	325
12	Solo: Doublet Identification in Single-Cell RNA-Seq via Semi-Supervised Deep Learning Nicholas Bernstein, Nicole L. Fong, Irene Lam et al. · Cell Systems Open access	26 Jun 2020	309
13	Genetic architecture of 11 organ traits derived from abdominal MRI using deep learning Yi Liu, Nicolas Basty, Brandon J. Whitcher et al. · eLife Open access	14 Jun 2021	301
14	Myocardial Gene Expression Signatures in Human Heart Failure With Preserved Ejection Fraction Virginia Shalkey Hahn, Hildur Knútsdóttir, Xin Luo et al. · Circulation Open access	29 Oct 2020	295
15	Naked mole-rat mortality rates defy Gompertzian laws by not increasing with age J. Graham Ruby, Megan Smith, Rochelle Buffenstein · eLife Open access	24 Jan 2018	285
16	Predicting mRNA Abundance Directly from Genomic Sequence Using Deep Convolutional Neural Networks Vikram Agarwal, Jay Shendure · Cell Reports Open access	May 2020	281
17	Estimates of the Heritability of Human Longevity Are Substantially Inflated due to Assortative Mating J. Graham Ruby, Kevin M. Wright, Kristin A. Rand et al. · Genetics Open access	31 Oct 2018	279
18	A RORγt+ cell instructs gut microbiota-specific Treg cell differentiation Ranit Kedmi et al. · Nature Open access	7 Sep 2022	266
19	Cross-species regulatory sequence activity prediction David R. Kelley · PLoS Computational Biology Open access	20 Jul 2020	258
20	A systematic evaluation of the design and context dependencies of massively parallel reporter assays Jason C. Klein, Vikram Agarwal, Fumitaka Inoue et al. · Nature Methods Open access	12 Oct 2020	253
21	The ER membrane protein complex interacts cotranslationally to enable biogenesis of multipass membrane proteins Matthew J. Shurtleff, Daniel N. Itzhak, Jeffrey A. Hussmann et al. · eLife Open access	29 May 2018	251
22	eIF2B activator prevents neurological defects caused by a chronic integrated stress response Yao Liang Wong et al. · eLife Open access	9 Jan 2019	233
23	Predicting RNA-seq coverage from DNA sequence as a unifying model of gene regulation Johannes Linder, Divyanshi Srivastava, Han Yuan et al. · Nature Genetics Open access	8 Jan 2025	214
24	A versatile oblique plane microscope for large-scale and high-resolution imaging of subcellular dynamics Etai Sapoznik et al. · eLife Open access	12 Nov 2020	212
25	Murine single-cell RNA-seq reveals cell-identity- and tissue-specific trajectories of aging Jacob C. Kimmel, Lolita Penland, Nimrod D. Rubinstein et al. · Genome Research Open access	21 Nov 2019	207
26	A lysosomal switch triggers proteostasis renewal in the immortal C. elegans germ lineage K. Adam Bohnert, Cynthia J. Kenyon · Nature Open access	21 Nov 2017	198
27	The PTPN2/PTPN1 inhibitor ABBV-CLS-484 unleashes potent anti-tumour immunity Christina K. Baumgartner et al. · Nature Open access	4 Oct 2023	189
28	Dietary restriction impacts health and lifespan of genetically diverse mice Andrea Di Francesco et al. · Nature Open access	9 Oct 2024	188
29	An open-source platform for analyzing and sharing worm-behavior data Avelino Javer, Michael Currie, Chee Wai Lee et al. · Nature Methods Open access	21 Aug 2018	173
30	The genetic and biochemical determinants of mRNA degradation rates in mammals Vikram Agarwal, David R. Kelley · Genome biology Open access	23 Nov 2022	169
31	lentiMPRA and MPRAflow for high-throughput functional characterization of gene regulatory elements M. Grace Gordon, Fumitaka Inoue, Beth Martin et al. · Nature Protocols Open access	8 Jul 2020	168
32	Protein-metabolite interactomics of carbohydrate metabolism reveal regulation of lactate dehydrogenase Kevin B. Hicks et al. · Science Open access	10 Mar 2023	165
33	The intrinsic substrate specificity of the human tyrosine kinome Tomer M. Yaron et al. · Nature Open access	8 May 2024	160
34	DaXi—high-resolution, large imaging volume and multi-view single-objective light-sheet microscopy Bin Yang, Merlin Lange, Alfred Millett-Sikking et al. · Nature Methods Open access	21 Mar 2022	159
35	scBasset: sequence-based modeling of single-cell ATAC-seq using convolutional neural networks Han Yuan, David R. Kelley · Nature Methods	8 Aug 2022	156
36	The small molecule ISRIB rescues the stability and activity of Vanishing White Matter Disease eIF2B mutant complexes Yao Liang Wong, Lauren LeBon, Rohinton P. Edalji et al. · eLife Open access	28 Feb 2018	145
37	The lichen symbiosis re-viewed through the genomes of Cladonia grayi and its algal partner Asterochloris glomerata Daniele Armaleo et al. · BMC Genomics Open access	23 Jul 2019	144
38	MANF regulates metabolic and immune homeostasis in ageing and protects against liver damage Pedro Sousa‐Victor, Joana Neves, Wendy Cedron-Craft et al. · Nature Metabolism Open access	3 Jan 2019	136
39	The naked truth: a comprehensive clarification and classification of current ‘myths’ in naked mole‐rat biology Rochelle Buffenstein et al. · Biological reviews/Biological reviews of the Cambridge Philosophical Society ReviewOpen access	3 Sep 2021	133
40	Deep Proteome Analysis Identifies Age-Related Processes in C. elegans Vikram Narayan, Tony Ly, Ehsan Pourkarimi et al. · Cell Systems Open access	21 Jul 2016	133
41	Genetic regulation of the human plasma proteome in 54,306 UK Biobank participants Benjamin B. Sun et al. · bioRxiv (Cold Spring Harbor Laboratory) PreprintOpen access	18 Jun 2022	130
42	Single-cell transcriptomics of the naked mole-rat reveals unexpected features of mammalian immunity Hugo G. Hilton, Nimrod D. Rubinstein, Peter Janki et al. · PLoS Biology Open access	21 Nov 2019	128
43	Semisupervised adversarial neural networks for single-cell classification Jacob C. Kimmel, David R. Kelley · Genome Research Open access	24 Feb 2021	126
44	Protein kinase R and the integrated stress response drive immunopathology caused by mutations in the RNA deaminase ADAR1 Megan M. Maurano, Jessica M. Snyder, Caitlin F. Connelly et al. · Immunity Open access	2 Aug 2021	125
45	Are mitochondria the main contributor of reactive oxygen species in cells? Yufeng Zhang, Hoi Shan Wong · Journal of Experimental Biology Open access	Mar 2021	124
46	Nicotine promotes neuron survival and partially protects from Parkinson’s disease by suppressing SIRT6 Justin W. Nicholatos, Adam B. Francisco, Carolyn A. Bender et al. · Acta Neuropathologica Communications Open access	8 Nov 2018	124
47	An encyclopedia of enhancer-gene regulatory interactions in the human genome Andreas R. Gschwind et al. · bioRxiv (Cold Spring Harbor Laboratory) PreprintOpen access	13 Nov 2023	123
48	How a Mutation that Slows Aging Can Also Disproportionately Extend End-of-Life Decrepitude Katie Podshivalova, Rex A. Kerr, Cynthia J. Kenyon · Cell Reports Open access	Apr 2017	122
49	The Upsides and Downsides of Organelle Interconnectivity Daniel E. Gottschling, Thomas Nyström · Cell Open access	Mar 2017	113
50	The mitochondrial derived peptide humanin is a regulator of lifespan and healthspan Kelvin Yen et al. · Aging Open access	23 Jun 2020	109

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.