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Most cited papers from Cape Town Science Centre

What are the most cited papers from Cape Town Science Centre?

The most cited paper from Cape Town Science Centre is "A phase III randomized comparison of lapatinib plus capecitabine versus capecitabine alone in women with advanced breast cancer that has progressed on trastuzumab: updated efficacy and biomarker analyses" (David Cameron et al., 2008), with 810 citations. Next come "A new scenario framework for climate change research: the concept of shared climate policy assumptions" (568) and "Tocilizumab inhibits structural joint damage in rheumatoid arthritis patients with inadequate responses to methotrexate: Results from the double-blind treatment phase of a randomized placebo-controlled trial of tocilizumab safety and prevention of structu" (416).

Showing 50 of 60 papers. Every paper with more than 19 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 A phase III randomized comparison of lapatinib plus capecitabine versus capecitabine alone in women with advanced breast cancer that has progressed on trastuzumab: updated efficacy and biomarker analyses David Cameron et al. · Breast Cancer Research and Treatment 10 Jan 2008 810
2 A new scenario framework for climate change research: the concept of shared climate policy assumptions Elmar Kriegler, Jae Edmonds, Stéphane Hallegatte et al. · Climatic Change Open access 27 Jan 2014 568
3 Tocilizumab inhibits structural joint damage in rheumatoid arthritis patients with inadequate responses to methotrexate: Results from the double-blind treatment phase of a randomized placebo-controlled trial of tocilizumab safety and prevention of structu Joel M. Kremer, Ricardo Blanco, Marek Brzosko et al. · Arthritis & Rheumatism 19 Nov 2010 416
4 Efficacy and Safety of Pimecrolimus Cream in the Long-Term Management of Atopic Dermatitis in Children Ulrich Wahn, Jan Dositheus Bos, Mark J. D. Goodfield et al. · PEDIATRICS Jul 2002 405
5 A reevaluation of the magnitude and impacts of anthropogenic atmospheric nitrogen inputs on the ocean T. D. Jickells et al. · Global Biogeochemical Cycles Open access 21 Jan 2017 276
6 Depression in Patients with Parkinsonism Ashley H. Robins · The British Journal of Psychiatry Feb 1976 185
7 Effectiveness and safety of the tri-iodothyronine analogue Triac in children and adults with MCT8 deficiency: an international, single-arm, open-label, phase 2 trial Stefan Groeneweg et al. · The Lancet Diabetes & Endocrinology Open access 31 Jul 2019 129
8 Tocilizumab Inhibits Structural Joint Damage and Improves Physical Function in Patients with Rheumatoid Arthritis and Inadequate Responses to Methotrexate: LITHE Study 2-year Results Roy Fleischmann, Anne-Marie Halland, Marek Brzosko et al. · The Journal of Rheumatology Open access 15 Jan 2013 123
9 Disease characteristics of MCT8 deficiency: an international, retrospective, multicentre cohort study Stefan Groeneweg et al. · The Lancet Diabetes & Endocrinology Open access 16 Jun 2020 118
10 Multiple forms of discrimination and internalized stigma compromise retention in HIV care among adolescents: findings from a South African cohort Marija Pantelic, Marisa A. J. Casale, Lucie Dale Cluver et al. · Journal of the International AIDS Society Open access May 2020 96
11 Subcutaneous Abatacept in Patients With Polyarticular‐Course Juvenile Idiopathic Arthritis Hermine I. Brunner et al. · Arthritis & Rheumatology Open access 26 Feb 2018 73
12 Evaluation of abatacept administered subcutaneously in adults with active rheumatoid arthritis: impact of withdrawal and reintroduction on immunogenicity, efficacy and safety (phase Iiib ALLOW study) Jeffrey Kaine, Geoffrey Gladstein, Ingrid Strusberg et al. · Annals of the Rheumatic Diseases Open access 15 Sep 2011 73
13 Quality Assurance and Quality Control in the Global Trachoma Mapping Project Anthony W. Solomon et al. · American Journal of Tropical Medicine and Hygiene Open access 24 Jul 2018 72
14 Immune correlates of the Thai RV144 HIV vaccine regimen in South Africa Glenda Gray et al. · Science Translational Medicine Open access 18 Sep 2019 71
15 C-Tb skin test to diagnose Mycobacterium tuberculosis infection in children and HIV-infected adults: A phase 3 trial Henrik Aggerbeck, Morten Rühwald, Soren Tetens Hoff et al. · PLoS ONE Open access 24 Sep 2018 71
16 Proactive community case-finding to facilitate treatment seeking for mental disorders, Nepal Mark J. D. Jordans, Brandon A. Kohrt, Nagendra P. Luitel et al. · Bulletin of the World Health Organization Open access 25 Apr 2017 70
17 Systematic analysis of authorship demographics in global surgery Krithi Ravi et al. · BMJ Global Health Open access Oct 2021 69
18 Global Approaches to the Prevention and Management of Delayed-onset Adverse Reactions with Hyaluronic Acid-based Fillers Wolfgang G. Philipp‐Dormston, Greg Julian Goodman, Koenraad De Boulle et al. · Plastic & Reconstructive Surgery Global Open Open access Apr 2020 68
19 Lessons learned from engaging men in sexual and reproductive health as clients, partners and advocates of change in the Hoima district of Uganda Erin A. Stern, Laura A. Pascoe, Tim Shand et al. · Culture Health & Sexuality Open access 8 May 2015 67
20 Canine babesiosis in South Africa: more than one disease. Does this serve as a model for falciparum malaria? F. Reyers, Andrew L. Leisewitz, Remo G. Lobetti et al. · Annals of Tropical Medicine and Parasitology Open access 1998 59
21 Meeting the Global Demand of Sports Safety Toomas Timpka, Caroline F. Finch, Claude Goulet et al. · Sports Medicine 2008 58
22 Antiretroviral Therapy and TB Notification Rates in a High HIV Prevalence South African Community Keren Middelkoop, Linda‐Gail Bekker, Landon Myer et al. · JAIDS Journal of Acquired Immune Deficiency Syndromes Open access 11 Feb 2011 57
23 South Africa's Experience of the Closure of the Cellulose Sulphate Microbicide Trial Gita Ramjee, Roshini Govinden, Neetha Shagan Morar et al. · PLoS Medicine Open access 27 Jul 2007 53
24 Maternal choline supplementation mitigates alcohol exposure effects on neonatal brain volumes Fleur L. Warton, Christopher D. Molteno, Christopher M. R. Warton et al. · Alcoholism Clinical and Experimental Research Open access 2 Aug 2021 51
25 Characterization of Patients with Embolic Strokes of Undetermined Source in the NAVIGATE ESUS Randomized Trial Scott Eric Kasner et al. · Journal of Stroke and Cerebrovascular Diseases Open access 8 Mar 2018 51
26 Training intensity distribution analysis by race pace vs. physiological approach in world‐class middle‐ and long‐distance runners Mark Kenneally, Arturo Casado, Josu Gomez‐Ezeiza et al. · European Journal of Sport Science 25 May 2020 50
27 Two randomized controlled trials of SB742457 in mild‐to‐moderate Alzheimer's disease Gareth Maher‐Edwards, Carolyn B. Watson, John A. Ascher et al. · Alzheimer s & Dementia Translational Research & Clinical Interventions Open access 6 May 2015 46
28 Ethnic disparities in fertility and its determinants in Nigeria Ayo Stephen Adebowale · Fertility Research and Practice Open access 30 Mar 2019 42
29 Lithium as add-on to quetiapine XR in adult patients with acute mania: a 6-week, multicenter, double-blind, randomized, placebo-controlled study Michel Bourin, Emanuel Severus, Juan Schronen et al. · International Journal of Bipolar Disorders Open access 7 Nov 2014 42
30 Factors Associated with Preferences for Long-Acting Injectable Antiretroviral Therapy Among Adolescents and Young People Living with HIV in South Africa Elona Toska, Siyanai Zhou, Jenny Chen‐Charles et al. · AIDS and Behavior Open access 9 Jan 2023 40
31 Phase 1 Human Immunodeficiency Virus (HIV) Vaccine Trial to Evaluate the Safety and Immunogenicity of HIV Subtype C DNA and MF59-Adjuvanted Subtype C Envelope Protein Mina C. Hosseinipour et al. · Clinical Infectious Diseases Open access 2020 35
32 Real‐time simultaneous shim and motion measurement and correction in glycoCEST MRI using double volumetric navigators (DvNavs) Gizeaddis Lamesgin Simegn, Andre J. W. van der Kouwe, Frances C. Robertson et al. · Magnetic Resonance in Medicine Open access 2 Dec 2018 34
33 Rapid Bioassessment Protocols Using Aquatic Macroinvertebrates in Africa–Considerations for Regional Adaptation of Existing Biotic Indices Helen F. Dallas · Frontiers in Water Open access 25 Feb 2021 33
34 A Review of Length Validation Methods and Protocols to Measure Large White Sharks Henry F. Mollet, David A. Ebert, Gregor M. Cailliet et al. · Elsevier eBooks Book chapter 1996 33
35 Prevalence and long‐term outcome of sub‐clinical primary sclerosing cholangitis in patients with ulcerative colitis Emma Louise Culver, Helen K. Bungay, Margaret Betts et al. · Liver International Open access 26 Aug 2020 31
36 Efficacy and safety of golimumab as add-on therapy to disease-modifying antirheumatic drugs: results of the GO-MORE study Bernard G Combe, Bhaskar Dasgupta, Ingrid Louw et al. · Annals of the Rheumatic Diseases Open access 6 Jun 2013 31
37 Intended and unintended consequences of student use of an online questioning environment Dick Ng’ambi, Irwin Brown · British Journal of Educational Technology 25 Nov 2008 31
38 Bone Mineral Density and Lifetime Physical Activity in South African Women Lisa Kim Micklesfield, Lynn A. Rosenberg, Diane D Cooper et al. · Calcified Tissue International Oct 2003 31
39 Differential expression of transforming growth factor alpha, adhesions molecules and integrins in primary, metastatic liver tumors and in liver cirrhosis. Kacper Jaśkiewicz, Martin Robert Chasen · PubMed 23 Jun 1995 30
40 Metabolic Effects of Paliperidone Extended Release Versus Oral Olanzapine in Patients With Schizophrenia Andreas Schreiner, Dana J.H. Niehaus, Nasser Shuriquie et al. · Journal of Clinical Psychopharmacology 20 Jun 2012 29
41 New possibilities for research on reef fish across the continental shelf of South Africa Anthony T.F. Bernard, A Götz, D. Stott Parker et al. · South African Journal of Science Open access 22 Sep 2014 29
42 Vulnerability of Cape Fold Ecoregion freshwater fishes to climate change and other human impacts Jeremy M. Shelton, Olaf L. F. Weyl, Albert Chakona et al. · Aquatic Conservation Marine and Freshwater Ecosystems Open access 6 Dec 2017 28
43 Prediction of remission and low disease activity in disease-modifying anti-rheumatic drug-refractory patients with rheumatoid arthritis treated with golimumab Nathan Vastesaeger, Abraham García Kutzbach, Howard Amital et al. · Lara D. Veeken Open access 25 Apr 2016 27
44 Efficacy and Safety of Obinutuzumab in Active Systemic Lupus Erythematosus Richard A. Furie et al. · New England Journal of Medicine 6 Mar 2026 25
45 Nurse-led care for the management of rheumatoid arthritis: a review of the global literature and proposed strategies for implementation in Africa and the Middle East Imad W. Uthman, Hani M. Almoallim, Christopher Dominic Buckley et al. · Rheumatology International Open access 26 Aug 2020 25
46 Clinical efficacy and safety maintained up to 5 years in patients with rheumatoid arthritis treated with tocilizumab in a randomised trial. Joel M. Kremer, Ricardo Blanco, Anne-Marie Halland et al. · PubMed 13 Sep 2016 25
47 A Neurometabolic Pattern of Elevated Myo-Inositol in Children Who Are HIV-Exposed and Uninfected: A South African Birth Cohort Study Cesc Bertran-Cobo, Catherine J. Wedderburn, Frances C. Robertson et al. · Frontiers in Immunology Open access 28 Mar 2022 24
48 OMIP‐056: Evaluation of Human Conventional T Cells, Donor‐Unrestricted T Cells, and NK Cells Including Memory Phenotype by Intracellular Cytokine Staining One Dintwe, Shamiska Rohith, Katharine V. Schwedhelm et al. · Cytometry Part A Open access 28 Mar 2019 23
49 Techno‐economic performance of sustainable international bio‐SNG production and supply chains on short and longer term Bothwell Batidzirai, Geert S. Schotman, Mijndert W. van der Spek et al. · Biofuels Bioproducts and Biorefining Open access 5 Aug 2018 23
50 Considerations for the Use of Minimally Invasive Aesthetic Procedures for Facial Remodeling in Transgender Individuals Koenraad De Boulle, Nobutaka Furuyama, Izolda Heydenrych et al. · Clinical Cosmetic and Investigational Dermatology Open access May 2021 22

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.