| 1 |
Changes in Biomarkers of Exposure on Switching From a Conventional Cigarette to Tobacco Heating Products: A Randomized, Controlled Study in Healthy Japanese Subjects
Nathan Gale, Mike McEwan, Alison C. Eldridge et al. · Nicotine & Tobacco Research
Open access |
17 May 2018 |
95 |
| 2 |
Effect of the inhaled PDE4 inhibitor CHF6001 on biomarkers of inflammation in COPD
Dave Singh, Kai Michael Beeh, Brendan Colgan et al. · Respiratory Research
Open access |
9 Aug 2019 |
81 |
| 3 |
Nicotine pharmacokinetics of electronic cigarettes: A review of the literature
Ian M. Fearon, Alison C. Eldridge, Nathan Gale et al. · Regulatory Toxicology and Pharmacology
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8 Sep 2018 |
58 |
| 4 |
Sputum and blood transcriptomics characterisation of the inhaled PDE4 inhibitor CHF6001 on top of triple therapy in patients with chronic bronchitis
Mirco Govoni, Michele Bassi, Stefano Vezzoli et al. · Respiratory Research
Open access |
20 Mar 2020 |
32 |
| 5 |
8th GCC: Consolidated Feedback to US FDA on The 2013 Draft FDA Guidance on Bioanalytical Method Validation
Joseph F. Bower et al. · Bioanalysis
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Nov 2014 |
32 |
| 6 |
The Impact of N-nitrosamine Impurities on Clinical Drug Development
Sabina Paglialunga, Aernout D. van Haarst · Journal of Pharmaceutical Sciences
Open access |
25 Jan 2023 |
29 |
| 7 |
Effects of combined GnRH receptor antagonist linzagolix and hormonal add-back therapy on vaginal bleeding—delayed add-back onset does not improve bleeding pattern
Oliver Pohl, Line Marchand, David Bell et al. · Reproductive Sciences
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25 Feb 2020 |
27 |
| 8 |
The Association for Human Pharmacology in the Pharmaceutical Industry London Meeting 2018: Brexit and Other Challenges in Early Phase Drug Development
Susan Reijntjes, Muna Albayaty, JAMES A. BUSH et al. · Frontiers in Pharmacology
Open access |
19 Nov 2018 |
26 |
| 9 |
Rifampin Drug–Drug–Interaction Studies: Reflections on the Nitrosamine Impurities Issue
Aernout D. van Haarst, Stephen W. Smith, Clare Garvin et al. · Clinical Pharmacology & Therapeutics
Open access |
20 May 2022 |
24 |
| 10 |
COPD sputum eosinophils: relationship to blood eosinophils and the effect of inhaled PDE4 inhibition
Dave Singh, Henrik Watz, Kai Michael Beeh et al. · European Respiratory Journal
Open access |
27 Apr 2020 |
24 |
| 11 |
Envelope domain analysis of measured time domain voltage and current waveforms provide for improved understanding of factors effecting linearity
David John Williams, J.G. Leckey, P.J. Tasker
Conference paper |
27 Aug 2003 |
22 |
| 12 |
2023 White Paper on Recent Issues in Bioanalysis: EU IVDR 2017/746 Implementation/Impact, IVD/CDx/CLIA Approved Assays, High Dimensional Cytometry, Multiplexing Technologies, LBA Tissue Analysis, Vaccine Study Endpoints, Cell-Based Assays for Biomarkers, Cell Therapy and Vaccines ( PART 2 – Recommendations on Development & Validation of Biomarkers, IVD, CDx, Cell-Based, Flow Cytometry, Ligand-Bind
Olga Kholmanskikh et al. · Bioanalysis
Open access |
17 Apr 2024 |
17 |
| 13 |
Adjusting for Patient Crossover in Clinical Trials Using External Data: A Case Study of Lenalidomide for Advanced Multiple Myeloma
K. Jack Ishak, J. Jaime, Mark Trehane Drayson et al. · Value in Health
Open access |
Jul 2011 |
14 |
| 14 |
Randomized trial of pharmacokinetic and pharmacodynamic effects of 13.2 mg intranasal epinephrine treatment in congestion
David A. Dworaczyk, Allen Gerhard Hunt, Mike Di Spirito et al. · Annals of Allergy Asthma & Immunology
Open access |
7 May 2024 |
12 |
| 15 |
Innovative Approaches to Optimize Clinical Transporter Drug–Drug Interaction Studies
Sabina Paglialunga, Natacha Benrimoh, Aernout D. van Haarst · Pharmaceutics
Open access |
26 Jul 2024 |
9 |
| 16 |
Should You Run a Dedicated TQT Study? Sponsor and Regulatory Considerations on Substitution Pathways to Assess QT Liability
Robert M. Lester, Caroline Engel, Aernout D. van Haarst et al. · Clinical Pharmacology & Therapeutics
Open access |
2 May 2024 |
9 |
| 17 |
Techniques for Hyaluronidase-Facilitated Subcutaneous Fluid Administration With Recombinant Human Hyaluronidase
Sandra M. Connolly, Helen Korzemba, George Harb et al. · Journal of Infusion Nursing
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Sep 2011 |
6 |
| 18 |
nanoCLAMP potently neutralizes SARS-CoV-2 and protects K18-hACE2 mice from infection
Quentin Pagneux, Nathalie Garnier, Manon Fabregue et al. · bioRxiv (Cold Spring Harbor Laboratory)
PreprintOpen access |
3 Apr 2023 |
4 |
| 19 |
13.2mg Intranasal Epinephrine Spray Demonstrates Comparable PK/PD and Safety to 0.3mg Epinephrine Autoinjector
David Dworaczyk, Allen Gerhard Hunt · Journal of Allergy and Clinical Immunology
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Feb 2023 |
4 |
| 20 |
The Association for Human Pharmacology in the Pharmaceutical Industry London Meeting October 2019: Impending Change, Innovation, and Future Challenges
Shahzadgai Khan, Muna Albayaty, JAMES A. BUSH et al. · Frontiers in Pharmacology
Open access |
19 Nov 2020 |
4 |
| 21 |
Pharmacokinetic and Pharmacodynamic Effects of Intranasal Epinephrine Versus Intramuscular Epinephrine in Adults
David Dworaczyk, Allen Hunt · Journal of Allergy and Clinical Immunology
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Feb 2020 |
4 |
| 22 |
126 A phase 1 clinical study of CTX-4430 in cystic fibrosis patients
Eric B. Springman, Ralph Grosswald, Edward E. Philpot et al. · Journal of Cystic Fibrosis
Open access |
Jun 2015 |
4 |
| 23 |
First-in-human study for londamocitinib (AZD4604), an inhaled selective JAK1 inhibitor
Tina Jellesmark Jensen, Camille Riff, Julia Lund et al. · Journal of Allergy and Clinical Immunology
Open access |
12 Jan 2026 |
3 |
| 24 |
HBT active antenna as a self-oscillating Doppler sensor
M.J. Kelly, Vincent Fusco, J.A.C. Stewart et al. · IEE Proceedings - Microwaves Antennas and Propagation
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2000 |
1 |
| 25 |
Safety and Pharmacokinetics (PK) of BLU-808 Following Oral Dosing in Healthy Volunteers
Anitha Suram, Ivan Lee, Huilan Yao et al. · Journal of Allergy and Clinical Immunology
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Feb 2025 |
0 |
| 26 |
COVID-19 and Re-Commencement of Early Phase Clinical Trials in Respiratory Medicine
Aernout D. van Haarst · International Journal of Pulmonary & Respiratory Sciences
Open access |
28 Jul 2021 |
0 |