| 1 |
p53 cooperates with DNA methylation and a suicidal interferon response to maintain epigenetic silencing of repeats and noncoding RNAs
Katerina I. Leonova, Leonid Brodsky, Brittany C. Lipchick et al. · Proceedings of the National Academy of Sciences
Open access |
10 Dec 2012 |
273 |
| 2 |
Proteotoxic stress targeted therapy (PSTT): induction of protein misfolding enhances the antitumor effect of the proteasome inhibitor bortezomib
Nickolay S. Neznanov, Andrei P. Komarov, Lubov Neznanova et al. · Oncotarget
Open access |
27 Mar 2011 |
92 |
| 3 |
Integrated high-throughput analysis identifies Sp1 as a crucial determinant of p53-mediated apoptosis
Haitao Li, Yu Zhang, Anda Ströse et al. · Cell Death and Differentiation
Open access |
27 Jun 2014 |
66 |
| 4 |
Anti-malaria drug blocks proteotoxic stress response: Anti-cancer implications
Nickolay S. Neznanov, Anton V. Gorbachev, Lubov Neznanova et al. · Cell Cycle
Open access |
Dec 2009 |
59 |
| 5 |
Azadiradione ameliorates polyglutamine expansion disease in Drosophila by potentiating DNA binding activity of heat shock factor 1
Vinod Kumar Nelson, Asif Ali, Naibedya Dutta et al. · Oncotarget
Open access |
26 Oct 2016 |
47 |
| 6 |
shRNA library screening identifies nucleocytoplasmic transport as a mediator of BCR-ABL1 kinase-independent resistance
Jamshid Sorouri Khorashad et al. · Blood
Open access |
9 Jan 2015 |
44 |
| 7 |
Measurement of Cancer Cell Growth Heterogeneity through Lentiviral Barcoding Identifies Clonal Dominance as a Characteristic of In Vivo Tumor Engraftment
Olivier Nolan-Stevaux, Donato Tedesco, Seamus P. Ragan et al. · PLoS ONE
Open access |
26 Jun 2013 |
41 |
| 8 |
Cancer cell-intrinsic resistance to BiTE therapy is mediated by loss of CD58 costimulation and modulation of the extrinsic apoptotic pathway
Ye Shen, Jason Samuel Eng, Flordeliza Fajardo et al. · Journal for ImmunoTherapy of Cancer
Open access |
Mar 2022 |
40 |
| 9 |
MDM4 Is Targeted by 1q Gain and Drives Disease in Burkitt Lymphoma
Jennifer Hüllein et al. · Cancer Research
Open access |
18 Apr 2019 |
38 |
| 10 |
Oncogenic context shapes the fitness landscape of tumor suppression
Lily M. Blair et al. · Nature Communications
Open access |
12 Oct 2023 |
33 |
| 11 |
Use of RNAi screens to uncover resistance mechanisms in cancer cells and identify synthetic lethal interactions
Paul Diehl, Donato Tedesco, Alex A. Chenchik · Drug Discovery Today Technologies
Open access |
7 Jan 2014 |
24 |
| 12 |
MicroRNA analysis suggests an additional level of feedback regulation in the NF-κB signaling cascade
Peter Mechtler, Ruchi Singhal, Julia V. Kichina et al. · Oncotarget
Open access |
16 May 2015 |
22 |
| 13 |
Peptides genetically selected for NF-κB activation cooperate with oncogene Ras and model carcinogenic role of inflammation
Venkatesh Natarajan, Andrei P. Komarov, Thomas Ippolito et al. · Proceedings of the National Academy of Sciences
Open access |
13 Jan 2014 |
18 |
| 14 |
31st Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2016): part two
Casey R. Ager et al. · Journal for ImmunoTherapy of Cancer
Open access1,802 authors |
Nov 2016 |
17 |
| 15 |
Long-Distance Effects of Insertional Mutagenesis
Ruchi Singhal, Xiaotao Deng, Alex A. Chenchik et al. · PLoS ONE
Open access |
5 Jan 2011 |
17 |
| 16 |
Protein kinase A type II-α regulatory subunit regulates the response of prostate cancer cells to taxane treatment
Evan R. Zynda, Vitaliy A. Matveev, Michael Makhanov et al. · Cell Cycle
Open access |
15 Oct 2014 |
15 |
| 17 |
Cholesteryl ester transfer protein (CETP) I405V polymorphism and cardiovascular disease in eastern European Caucasians – a cross-sectional study
Jasmin Bustami, Anna Sukiasyan, Juozas Kupčinskas et al. · BMC Geriatrics
Open access |
20 Jul 2016 |
12 |
| 18 |
Functional genetics-directed identification of novel pharmacological inhibitors of FAS- and TNF-dependent apoptosis that protect mice from acute liver failure
Andrei P. Komarov, Elena A. Komarova, K Green et al. · Cell Death and Disease
Open access |
17 Mar 2016 |
11 |
| 19 |
A Common Copy Number Variation Polymorphism in the CNTNAP2 Gene: Sexual Dimorphism in Association with Healthy Aging and Disease
Leonid Z. Iakoubov, Małgorzata Mossakowska, Małgorzata Szwed et al. · Gerontology
|
18 Aug 2014 |
11 |
| 20 |
Aberrant macrophage activation and maladaptive lung repair promote tuberculosis progression uniquely in the lung
Shivraj M. Yabaji, Suruchi Lata, Anna E. Tseng et al. · bioRxiv (Cold Spring Harbor Laboratory)
PreprintOpen access |
20 Oct 2023 |
8 |
| 21 |
Protocol for developing a mouse model of post-primary pulmonary tuberculosis after hematogenous spread in native lungs and lung implants
Shivraj M. Yabaji, Suruchi Lata, Igor Gavrish et al. · STAR Protocols
Open access |
25 Jul 2025 |
5 |
| 22 |
Dysplastic lung repair fosters a tuberculosis-promoting microenvironment through maladaptive macrophage polarization
Shivraj M. Yabaji, Suruchi Lata, Anna E. Tseng et al. · PLoS Pathogens
Open access |
6 Oct 2025 |
4 |
| 23 |
The CD4 T cell-independent IgG response during persistent virus infection favors emergence of neutralization-escape variants
Katelyn Nicole Ayers, Matthew D. Lauver, Kalynn M Alexander et al. · bioRxiv (Cold Spring Harbor Laboratory)
PreprintOpen access |
25 Dec 2024 |
4 |
| 24 |
TLR-6 SNP P249S is associated with healthy aging in nonsmoking Eastern European Caucasians - A cohort study
Lutz Hamann, Jasmin Bustami, Leonid Z. Iakoubov et al. · Immunity & Ageing
Open access |
17 Mar 2016 |
4 |
| 25 |
Elimination of senescent cells with senolytic host-directed therapy reduces tuberculosis progression in mice
Somnath Shee, Yazmin B. Martinez-Martinez, Benjamin N. Koleske et al. · bioRxiv (Cold Spring Harbor Laboratory)
PreprintOpen access |
28 Mar 2025 |
3 |
| 26 |
Lipid Peroxidation and Type I Interferon Coupling Fuels Pathogenic Macrophage Activation Causing Tuberculosis Susceptibility
Shivraj M. Yabaji, Vadim Zhernovkov, Prasanna Babu Araveti et al. · bioRxiv (Cold Spring Harbor Laboratory)
PreprintOpen access |
10 Mar 2024 |
3 |
| 27 |
MafK Mediates Chromatin Remodeling to Silence IRF8 Expression in Non-immune Cells in a Cell Type-SpecificManner
Nitsan Fourier, Maya Zolty, Aviva Azriel et al. · Journal of Molecular Biology
|
10 Jun 2020 |
3 |
| 28 |
Elimination of senescent cells with senolytic drugs as adjunctive host-directed therapy reduces tuberculosis progression in mice
Somnath Shee, Yazmin B. Martinez-Martinez, Benjamin Koleske et al. · Nature Communications
Open access |
7 May 2026 |
2 |
| 29 |
MDM4 is an essential disease driver targeted by 1q gain in Burkitt lymphoma
Jennifer Hüllein et al. · bioRxiv (Cold Spring Harbor Laboratory)
PreprintOpen access |
9 Apr 2018 |
2 |
| 30 |
An Unbiased shRNA Library Screen Identifies Nucleocytoplasmic Transport As a Potential Target For Treatment Of Chronic Myeloid Leukemia
Jamshid Sorouri Khorashad, Clinton C. Mason, Ira Lignugaris Kraft et al. · Blood
|
15 Nov 2013 |
2 |
| 31 |
cloneXplorer: A high-throughput clone discovery platform based on conical microwell arrays
Guido Stadler, Eugene Tkachenko, Oscar Neri et al. · bioRxiv (Cold Spring Harbor Laboratory)
PreprintOpen access |
20 Jan 2026 |
1 |
| 32 |
T-cell receptor/CD28-targeted immunotherapeutics selectively drive naive T-cell expansion to generate functional HIV-specific responses
April L. Mueller, Sara Lamcaj, S. Garforth et al. · Journal of Virology
Open access |
5 Aug 2025 |
1 |
| 33 |
The 10th Santorini conference: Systems medicine, personalised health and therapy. “The odyssey from hope to practice: Patient first. Keep Ithaca always in your mind”, Santorini, Greece, 23–26 May 2022
Sophie Visvikis‐Siest et al. · Frontiers in Genetics
Open access |
9 Mar 2023 |
1 |
| 34 |
Identification of Genes Specific for Viability of Prostate Cancer Cells using a Pooled Lentiviral shRNA Expression Library
Donato Tedesco, Mikhail Makhanov, Kyle R. Bonneau et al. · BioTechniques
Open access |
Mar 2012 |
1 |
| 35 |
Streamlined and cost-effective 96-well plate NGS assay for single-cell immune receptor chain pairing and T/B cell immunophenotyping 2260349
Alex Chenchik, Tianbing Liu, Dongfang Hu et al. · The Journal of Immunology
|
28 Jul 2026 |
0 |
| 36 |
High-throughput TCR-epitope screening using the Jurkat NFAT Reporter-K562 APC cell system on the Microwell ELISpot Platform 2258594
Alex Chenchik, Debbie Deng, Kitt Paraiso et al. · The Journal of Immunology
Open access |
28 Jul 2026 |
0 |
| 37 |
A mixed-methods evaluation of the quantitative and perceived impact of Brexit on UK oncology clinical trial initiation between 2011 and 2020
Millie Arora, Sean Elliott, Adrian Kilcoyne et al. · Journal of Pharmaceutical Policy and Practice
Open access |
15 Jun 2026 |
0 |
| 38 |
Screening of TCR-specific epitopes using peptide libraries in artificial antigen-presenting cells 3867
Debbie Deng, Tianbing Liu, Kitt Paraiso et al. · The Journal of Immunology
Open access |
Nov 2025 |
0 |
| 39 |
Save the mouse! Non-lethal, repeated blood transcriptome profiling in murine disease models 3386
Lester Kobzik, Alex Chenchik, Dongfang Hu et al. · The Journal of Immunology
Open access |
Nov 2025 |
0 |
| 40 |
Molecule template estimation using Validator Barcodes in multiplex PCR for adaptive immune repertoire profiling
Kitt D. Paraiso, Mark Izraelson, Alex Chenchik · bioRxiv (Cold Spring Harbor Laboratory)
PreprintOpen access |
7 Oct 2025 |
0 |
| 41 |
Clinically relevant CCR5 editing in primary CD4+ T cells with TALEN confers resistance to HIV-1 infection
Marianna Romito, Alexandre Juillerat, Yik Lim Kok et al.
PreprintOpen access |
19 May 2020 |
0 |
| 42 |
Adaptation of STARR-seq method to be used with 3 rd generation integrase-deficient promoterless lentiviral vectors
Mantas Matjusaitis, Donato Tedesco, Azuolas Ciukas · bioRxiv (Cold Spring Harbor Laboratory)
PreprintOpen access |
26 Jun 2020 |
0 |
| 43 |
MafK mediates chromatin remodeling to silence IRF8 expression in non-immune cells in a lineage-specific manner
Nitsan Fourier, Maya Zolty, Aviva Azriel et al. · bioRxiv (Cold Spring Harbor Laboratory)
PreprintOpen access |
20 Aug 2018 |
0 |
| 44 |
Cancer immunenet biomarker profiling panel
Alex A. Chenchik, Mikhail Makhanov, Leonid Z. Iakoubov et al. · Journal for ImmunoTherapy of Cancer
Open access |
4 Nov 2015 |
0 |