Science Explorer Back to mapMap
Institution · Center for Discovery

Most cited papers from Center for Discovery

What are the most cited papers from Center for Discovery?

The most cited paper from Center for Discovery is "The bone marrow microenvironment at single-cell resolution" (Anastasia N. Tikhonova et al., 2019), with 967 citations. Next come "The Fungal Cell Wall: Candida, Cryptococcus, and Aspergillus Species" (919) and "Medical molecular farming: production of antibodies, biopharmaceuticals and edible vaccines in plants" (753).

Showing 50 of 59 papers. Every paper with more than 159 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 The bone marrow microenvironment at single-cell resolution Anastasia N. Tikhonova et al. · Nature Open access 10 Apr 2019 967
2 The Fungal Cell Wall: Candida, Cryptococcus, and Aspergillus Species Rocio Garcia‐Rubio, Haroldo César de Oliveira, Johanna Rivera et al. · Frontiers in Microbiology Open access 8 Jan 2020 919
3 Medical molecular farming: production of antibodies, biopharmaceuticals and edible vaccines in plants Henry Daniell, Stephen J. Streatfield, Keith L. Wycoff · Trends in Plant Science ReviewOpen access May 2001 753
4 Protease inhibitors targeting coronavirus and filovirus entry Yanchen Zhou, Punitha Vedantham, Kai Lü et al. · Antiviral Research Open access 7 Feb 2015 626
5 Anti-tuberculosis treatment strategies and drug development: challenges and priorities Veronique Anne Dartois, Eric J. Rubin · Nature Reviews Microbiology ReviewOpen access 27 Apr 2022 501
6 Plasmid-encoded tet(X) genes that confer high-level tigecycline resistance in Escherichia coli Jian Ge Sun et al. · Nature Microbiology Open access 24 Jun 2019 501
7 The Antifungal Pipeline: Fosmanogepix, Ibrexafungerp, Olorofim, Opelconazole, and Rezafungin Martin Hoenigl, Rosanne Sprute, Matthias Egger et al. · Drugs Open access Oct 2021 459
8 Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond Wesley C. Van Voorhis et al. · PLoS Pathogens Open access187 authors 28 Jul 2016 452
9 The emergence of COVID-19 associated mucormycosis: a review of cases from 18 countries Martin Hoenigl, Danila Seidel, Agostinho Carvalho et al. · The Lancet Microbe Open access 25 Jan 2022 450
10 COVID-19 Associated Pulmonary Aspergillosis (CAPA)—From Immunology to Treatment Amir A. Arastehfar, Agostinho Carvalho, Frank L. van de Veerdonk et al. · Journal of Fungi Open access 24 Jun 2020 432
11 Human genetic and immunological determinants of critical COVID-19 pneumonia Qian Zhang et al. · Nature Open access163 authors 28 Jan 2022 396
12 Emerging Antimicrobial-Resistant High-Risk Klebsiella pneumoniae Clones ST307 and ST147 Gisele Peirano, Liang Chen, Barry N. Kreiswirth et al. · Antimicrobial Agents and Chemotherapy Open access 3 Aug 2020 385
13 Screening and Management of Depression in Patients With Cardiovascular Disease Manish K. Jha, Arman Qamar, Muthiah Vaduganathan et al. · Journal of the American College of Cardiology Open access Apr 2019 364
14 Clinical outcomes and bacterial characteristics of carbapenem-resistant Klebsiella pneumoniae complex among patients from different global regions (CRACKLE-2): a prospective, multicentre, cohort study Minggui Wang et al. · The Lancet Infectious Diseases Open access114 authors 9 Nov 2021 363
15 High throughput docking for library design and library prioritization David Diller, Kenneth M. Merz · Proteins Structure Function and Bioinformatics 2001 353
16 Molecular and clinical epidemiology of carbapenem-resistant Enterobacterales in the USA (CRACKLE-2): a prospective cohort study David van Duin et al. · The Lancet Infectious Diseases Open access 6 Mar 2020 346
17 Fatty acid synthesis is required for breast cancer brain metastasis Gino B. Ferraro et al. · Nature Cancer Open access Apr 2021 335
18 Virulence Factors in Hypervirulent Klebsiella pneumoniae Jie Zhu, Tao Wang, Liang Chen et al. · Frontiers in Microbiology Open access 8 Apr 2021 334
19 Persistence of symptoms and quality of life at 35 days after hospitalization for COVID-19 infection Laurie G. Jacobs, Elli Gourna Paleoudis, Dineen Lesky-Di Bari et al. · PLoS ONE Open access 11 Dec 2020 334
20 Global epidemiology and clinical outcomes of carbapenem-resistant Pseudomonas aeruginosa and associated carbapenemases (POP): a prospective cohort study Jinnethe Reyes et al. · The Lancet Microbe Open access 9 Feb 2023 323
21 Diversity of P450 enzymes in the biosynthesis of natural products Larissa M. Podust, David H. Sherman · Natural Product Reports Open access 2012 322
22 Adenomatous Polyps Are Driven by Microbe-Instigated Focal Inflammation and Are Controlled by IL-10–Producing T Cells Kristen L. Dennis, Yunwei Wang, Nichole Renee Blatner et al. · Cancer Research Open access 17 Aug 2013 320
23 AKI Treated with Renal Replacement Therapy in Critically Ill Patients with COVID-19 Shruti Gupta et al. · Journal of the American Society of Nephrology Open access 16 Oct 2020 316
24 Anthropogenic climate change is worsening North American pollen seasons William R. L. Anderegg, John T. Abatzoglou, Leander D. L. Anderegg et al. · Proceedings of the National Academy of Sciences Open access 8 Feb 2021 303
25 Drug-Resistant Fungi: An Emerging Challenge Threatening Our Limited Antifungal Armamentarium Amir A. Arastehfar, Toni Gabaldón, Rocio Garcia‐Rubio et al. · Antibiotics Open access 8 Dec 2020 300
26 Association of Depression and Cardiovascular Disease Chayakrit Krittanawong, Neil Sagar Maitra, Yusuf Kamran Qadeer et al. · The American Journal of Medicine Open access 27 May 2023 297
27 Role of astroglial toll-like receptors (TLRs) in central nervous system infections, injury and neurodegenerative diseases Lun Li, Çiğdem Acıoğlu, Robert F. Heary et al. · Brain Behavior and Immunity Open access 8 Oct 2020 283
28 The ribonuclease activity of SAMHD1 is required for HIV-1 restriction Jeongmin Ryoo, Jongsu Choi, Changhoon Oh et al. · Nature Medicine Open access 16 Jul 2014 279
29 Maternal prenatal stress phenotypes associate with fetal neurodevelopment and birth outcomes Kate Walsh, Clare A. McCormack, Rachel Webster et al. · Proceedings of the National Academy of Sciences Open access 14 Oct 2019 275
30 COVID-19-Associated Candidiasis (CAC): An Underestimated Complication in the Absence of Immunological Predispositions? Amir A. Arastehfar, Agostinho Carvalho, M. Hong Nguyen et al. · Journal of Fungi Open access 8 Oct 2020 273
31 A feature-based, robust, hierarchical algorithm for registering pairs of images of the curved human retina Ali Can, Charles V. Stewart, Badrinath Roysam et al. · IEEE Transactions on Pattern Analysis and Machine Intelligence Mar 2002 271
32 Discovery of Inhibitors that Elucidate the Role of UCH-L1 Activity in the H1299 Lung Cancer Cell Line Yichin Liu, Hilal Ahmed Lashuel, Sung‐Woon Choi et al. · Chemistry & Biology Open access Sep 2003 262
33 Antibiotics for cancer treatment: A double-edged sword Yuan Gao, Qingyao Shang, Wenyu Li et al. · Journal of Cancer Open access 2020 255
34 Caenorhabditis elegans is a useful model for anthelmintic discovery Andrew R. Burns et al. · Nature Communications Open access 25 Jun 2015 255
35 Worldwide emergence of fluconazole-resistant Candida parapsilosis: current framework and future research roadmap Farnaz Daneshnia, João Nóbrega de Almeida, Macit İlkit et al. · The Lancet Microbe Open access 27 Apr 2023 253
36 TCF1 in T cell immunity: a broadened frontier Xudong Zhao, Qiang Shan, Hai‐Hui Xue · Nature reviews. Immunology Review 14 Jun 2021 253
37 CRISPRi chemical genetics and comparative genomics identify genes mediating drug potency in Mycobacterium tuberculosis Shuqi Li, Nicholas C. Poulton, Jesseon S. Chang et al. · Nature Microbiology Open access 30 May 2022 246
38 A single-cell RNA-seq atlas of Schistosoma mansoni identifies a key regulator of blood feeding George Russel Wendt, Lu Zhao, Rui Chen et al. · Science Open access 25 Sep 2020 243
39 Aspergillus fumigatusand aspergillosis: From basics to clinics Amir A. Arastehfar et al. · Studies in Mycology Open access 10 May 2021 242
40 The role of the locus coeruleus in the generation of pathological anxiety Laurel S. Morris, Jordan G. McCall, Dennis S. Charney et al. · Brain and Neuroscience Advances Open access 2020 237
41 A naturally inspired antibiotic to target multidrug-resistant pathogens Zongqiang Wang, Bimal Koirala, Yozen A. Hernandez et al. · Nature Open access 5 Jan 2022 236
42 The importance of antimicrobial resistance in medical mycology Neil A. R. Gow, Carolyn Johnson, Judith G. Berman et al. · Nature Communications Open access 12 Sep 2022 230
43 On what motivates us: a detailed review of intrinsic v. extrinsic motivation Laurel S. Morris, Mora M. Grehl, Sarah Rutter et al. · Psychological Medicine Open access Jul 2022 223
44 Global guideline for the diagnosis and management of rare yeast infections: an initiative of the ECMM in cooperation with ISHAM and ASM Sharon C.‐A. Chen et al. · The Lancet Infectious Diseases Open access 19 Aug 2021 218
45 New insights into the machinery of blood digestion by ticks Daniel Sojka, Zdeněk Franta, Martin Horn et al. · Trends in Parasitology Review 7 May 2013 217
46 The Environmental Influences on Child Health Outcomes (ECHO)-Wide Cohort Emily A. Knapp et al. · American Journal of Epidemiology Open access 24 Mar 2023 211
47 Power from nature: designing green battery materials from electroactive quinone derivatives and organic polymers Mikhail M. Miroshnikov, Kizhmuri P. Divya, Ganguli Babu et al. · Journal of Materials Chemistry A 2016 202
48 Global identification of peptidase specificity by multiplex substrate profiling Anthony John O’Donoghue, A.A. Eroy-Reveles, Giselle M. Knudsen et al. · Nature Methods Open access 30 Sep 2012 200
49 Structure and functional characterization of the atypical human kinase haspin Jeyanthy Eswaran, Debasis Patnaik, P. Filippakopoulos et al. · Proceedings of the National Academy of Sciences Open access 16 Nov 2009 197
50 Effect of Ventral vs Dorsal Spinal Surgery on Patient-Reported Physical Functioning in Patients With Cervical Spondylotic Myelopathy Zoher Ghogawala et al. · JAMA Open access 9 Mar 2021 194

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.