Most cited papers from Center for Human Genetics

Center for Human Genetics

What are the most cited papers from Center for Human Genetics?

The most cited paper from Center for Human Genetics is "PLINK: A Tool Set for Whole-Genome Association and Population-Based Linkage Analyses" (Shaun Purcell, Benjamin M. Neale, Katherine EO Todd-Brown et al., 2007), with 36,890 citations. Next come "The organization of the human cerebral cortex estimated by intrinsic functional connectivity" (10,128) and "Finding the missing heritability of complex diseases" (8,637).

Published TypeFieldAccessAuthorsCitations

Showing 50 of 60 papers. Every paper with more than 1,523 citations is listed.

Most cited papers, sortable by citations and release date
#	Paper
1	PLINK: A Tool Set for Whole-Genome Association and Population-Based Linkage Analyses Shaun Purcell, Benjamin M. Neale, Katherine EO Todd-Brown et al. · The American Journal of Human Genetics Open access	8 Aug 2007	36,890
2	The organization of the human cerebral cortex estimated by intrinsic functional connectivity B.T. Thomas Yeo, Fenna M. Krienen, Jorge Sepulcre et al. · Journal of Neurophysiology Open access	9 Jun 2011	10,128
3	Finding the missing heritability of complex diseases Teri A. Manolio et al. · Nature Open access	Oct 2009	8,637
4	An integrated map of genetic variation from 1,092 human genomes Gil A. McVean et al. · Nature Open access363 authors	31 Oct 2012	8,281
5	A map of human genome variation from population-scale sequencing Richard M. Durbin et al. · Nature Open access337 authors	26 Oct 2010	8,156
6	Initial sequencing and comparative analysis of the mouse genome Asif T. Chinwalla et al. · Nature Open access223 authors	Dec 2002	7,343
7	Statistical Tests of Neutrality of Mutations Against Population Growth, Hitchhiking and Background Selection Yun‐Xin Fu · Genetics Open access	Oct 1997	7,294
8	A Gene-Expression Signature as a Predictor of Survival in Breast Cancer Marc J. van de Vijver et al. · New England Journal of Medicine Open access	18 Dec 2002	6,562
9	Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) Daniel J. Klionsky et al. · Autophagy Open access2,467 authors	2 Jan 2016	6,023
10	The Connectivity Map: Using Gene-Expression Signatures to Connect Small Molecules, Genes, and Disease Justin Lamb, Emily D. Crawford, David D. Peck et al. · Science	28 Sep 2006	5,546
11	Genetic studies of body mass index yield new insights for obesity biology The LifeLines Cohort Study et al. · Nature Open access487 authors	10 Feb 2015	4,954
12	Host–microbe interactions have shaped the genetic architecture of inflammatory bowel disease Luke Jostins et al. · Nature Open access106 authors	31 Oct 2012	4,928
13	Age-Related Clonal Hematopoiesis Associated with Adverse Outcomes Siddhartha Jaiswal et al. · New England Journal of Medicine Open access	26 Nov 2014	4,900
14	Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease European Alzheimer's Disease Initiative (EADI) et al. · Nature Genetics ReviewOpen access184 authors	27 Oct 2013	4,711
15	A System for Stable Expression of Short Interfering RNAs in Mammalian Cells Thijn R. Brummelkamp, René Bernards, Reuven Agami · Science Open access	19 Apr 2002	4,319
16	Biological, clinical and population relevance of 95 loci for blood lipids Tanya M. Teslovich et al. · Nature Open access209 authors	Aug 2010	3,706
17	Genetic Dissection of Complex Traits Eric S. Lander, Nicholas J. Schork · Science	30 Sep 1994	3,468
18	Osteoblastic cells regulate the haematopoietic stem cell niche Laura Maria Calvi, Gary B. Adams, Kathryn W. Weibrecht et al. · Nature	Oct 2003	3,462
19	Sequence Variations in PCSK9, Low LDL, and Protection against Coronary Heart Disease Jonathan C. Cohen, Eric Boerwinkle, Thomas H. Mosley et al. · New England Journal of Medicine Open access	22 Mar 2006	3,254
20	Metabolite profiles and the risk of developing diabetes Thomas J. Wang, Martin G. Larson, Ramachandran Srini Vasan et al. · Nature Medicine Open access	20 Mar 2011	3,202
21	Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index MAGIC et al. · Nature Genetics Open access376 authors	10 Oct 2010	2,999
22	Genome-Wide Association Analysis Identifies Loci for Type 2 Diabetes and Triglyceride Levels Richa Saxena et al. · Science	26 Apr 2007	2,892
23	Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis Stephen J. Sawcer et al. · Nature Open access241 authors	Aug 2011	2,772
24	A comprehensive 1000 Genomes–based genome-wide association meta-analysis of coronary artery disease Majid Nikpay et al. · Nature Genetics ReviewOpen access151 authors	7 Sep 2015	2,733
25	Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease Jeffrey C. Barrett et al. · Nature Genetics Open access	29 Jun 2008	2,644
26	Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci André Franke et al. · Nature Genetics Open access	21 Nov 2010	2,592
27	The GPR54 Gene as a Regulator of Puberty Stephanie Beth Seminara, Sophie Messager, Emmanouella E. Chatzidaki et al. · New England Journal of Medicine Open access	22 Oct 2003	2,568
28	Complement Factor H Variant Increases the Risk of Age-Related Macular Degeneration Jonathan L. Haines, Michael A. Hauser, Silke Schmidt et al. · Science	10 Mar 2005	2,436
29	Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs S Hong Lee et al. · Nature Genetics Open access370 authors	11 Aug 2013	2,374
30	Genome-wide detection and characterization of positive selection in human populations Pardis Christine Sabeti, Patrick Varilly, Ben N. Fry et al. · Nature Open access	Oct 2007	2,312
31	New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk Josée Dupuis et al. · Nature Genetics Open access263 authors	17 Jan 2010	2,239
32	De novo mutations revealed by whole-exome sequencing are strongly associated with autism Stephan Sanders et al. · Nature Open access	3 Apr 2012	2,197
33	Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk Georg Ehret et al. · Nature Open access346 authors	9 Sep 2011	2,085
34	Functional impact of global rare copy number variation in autism spectrum disorders Dalila Pinto et al. · Nature Open access177 authors	8 Jun 2010	2,073
35	The Cellular Phase of Alzheimer’s Disease Bart De Strooper, Eric H. Karran · Cell Open access	Feb 2016	2,066
36	Hundreds of variants clustered in genomic loci and biological pathways affect human height Hana Lango Allen et al. · Nature Open access293 authors	29 Sep 2010	2,063
37	A Mitochondrial Protein Compendium Elucidates Complex I Disease Biology David J. Pagliarini, Sarah E. Calvo, Betty Y Chang et al. · Cell Open access	Jul 2008	2,040
38	Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes Andrew Paul Morris et al. · Nature Genetics Open access204 authors	12 Aug 2012	2,021
39	Efficient Control of Population Structure in Model Organism Association Mapping Hyun Min Kang, Noah Zaitlen, Claire M. Wade et al. · Genetics Open access	Mar 2008	1,993
40	Genome-wide association study identifies five new schizophrenia loci Stephan Ripke et al. · Nature Genetics Open access196 authors	18 Sep 2011	1,966
41	Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease Cardiogenics et al. · Nature Genetics Open access167 authors	6 Mar 2011	1,959
42	Syndecan–syntenin–ALIX regulates the biogenesis of exosomes Maria Francesca Baietti, Zhe Zhang, Eva Mortier et al. · Nature Cell Biology	3 Jun 2012	1,923
43	Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes Eleftheria Zeggini et al. · Nature Genetics ReviewOpen access	30 Mar 2008	1,880
44	Phenotype molding of stromal cells in the lung tumor microenvironment Diether Lambrechts, Els Wauters, Bram Boeckx et al. · Nature Medicine	6 Jul 2018	1,805
45	Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis The MAGIC investigators et al. · Nature Genetics Open access159 authors	27 Jun 2010	1,801
46	50 year trends in atrial fibrillation prevalence, incidence, risk factors, and mortality in the Framingham Heart Study: a cohort study Renate B. Schnabel, Xiaoyan Yin, Philimon Nyakauru Gona et al. · The Lancet Open access	7 May 2015	1,789
47	Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis John David Rioux et al. · Nature Genetics Open access	15 Apr 2007	1,775
48	The landscape of cancer genes and mutational processes in breast cancer Philip J. Stephens et al. · Nature Open access	15 May 2012	1,740
49	New genetic loci link adipose and insulin biology to body fat distribution Dmitry Shungin et al. · Nature Open access410 authors	10 Feb 2015	1,726
50	Large-scale association analysis identifies new risk loci for coronary artery disease Panos Deloukas et al. · Nature Genetics Open access183 authors	2 Dec 2012	1,681

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.