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Most cited papers from Centre Georges François Leclerc

What are the most cited papers from Centre Georges François Leclerc?

The most cited paper from Centre Georges François Leclerc is "FOLFIRINOX versus Gemcitabine for Metastatic Pancreatic Cancer" (Thierry Conroy, Françoise Desseigne, Marc Ychou et al., 2011), with 7,927 citations. Next come "Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018" (6,760) and "Gut microbiome influences efficacy of PD-1–based immunotherapy against epithelial tumors" (5,679).

Showing 50 of 60 papers. Every paper with more than 391 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 FOLFIRINOX versus Gemcitabine for Metastatic Pancreatic Cancer Thierry Conroy, Françoise Desseigne, Marc Ychou et al. · New England Journal of Medicine Open access 11 May 2011 7,927
2 Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018 Lorenzo Galluzzi et al. · Cell Death and Differentiation Open access169 authors 23 Jan 2018 6,760
3 Gut microbiome influences efficacy of PD-1–based immunotherapy against epithelial tumors Bertrand Routy et al. · Science 2 Nov 2017 5,679
4 Postoperative Irradiation with or without Concomitant Chemotherapy for Locally Advanced Head and Neck Cancer Jacques Bernier, Christian Domenge, Mahmut Özsahin et al. · New England Journal of Medicine Open access 5 May 2004 3,214
5 Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition) 1 Daniel J. Klionsky et al. · Autophagy Open access2,930 authors 2 Jan 2021 2,743
6 70-Gene Signature as an Aid to Treatment Decisions in Early-Stage Breast Cancer Fátima Cardoso et al. · New England Journal of Medicine Open access 24 Aug 2016 2,097
7 The Intestinal Microbiota Modulates the Anticancer Immune Effects of Cyclophosphamide Sophie Viaud et al. · Science Open access 21 Nov 2013 2,053
8 Activation of the NLRP3 inflammasome in dendritic cells induces IL-1β–dependent adaptive immunity against tumors François Ghiringhelli et al. · Nature Medicine Open access 20 Sep 2009 1,881
9 Immunological aspects of cancer chemotherapy Laurence Zitvogel, Lionel Apétoh, François Ghiringhelli et al. · Nature reviews. Immunology Review 21 Dec 2007 1,720
10 Recommendations from gynaecological (GYN) GEC ESTRO working group (II): Concepts and terms in 3D image-based treatment planning in cervix cancer brachytherapy—3D dose volume parameters and aspects of 3D image-based anatomy, radiation physics, radiobiology Richard Pötter, Christine Haie-Méder, Erik Van Limbergen et al. · Radiotherapy and Oncology 2006 1,634
11 Autophagy-Dependent Anticancer Immune Responses Induced by Chemotherapeutic Agents in Mice Mickaël Michaud, Isabelle Martins, Abdul Qader Sukkurwala et al. · Science 15 Dec 2011 1,361
12 Immunogenic death of colon cancer cells treated with oxaliplatin Antoine Tesnière, Frédéric Schlemmer, Valérie Boige et al. · Oncogene 2 Nov 2009 1,174
13 Molecularly targeted therapy based on tumour molecular profiling versus conventional therapy for advanced cancer (SHIVA): a multicentre, open-label, proof-of-concept, randomised, controlled phase 2 trial Christophe Le Tourneau et al. · The Lancet Oncology 3 Sep 2015 1,144
14 Hyperfractionated or accelerated radiotherapy in head and neck cancer: a meta-analysis Jean Bourhis, Jens Overgaard, Hélène Audry et al. · The Lancet Review 18 Aug 2006 1,087
15 Cancer cell–autonomous contribution of type I interferon signaling to the efficacy of chemotherapy Antonella Sistigu et al. · Nature Medicine 26 Oct 2014 1,063
16 Internal Mammary and Medial Supraclavicular Irradiation in Breast Cancer Philip M. Poortmans et al. · New England Journal of Medicine Open access 22 Jul 2015 1,033
17 Membrane-associated Hsp72 from tumor-derived exosomes mediates STAT3-dependent immunosuppressive function of mouse and human myeloid-derived suppressor cells Fanny Chalmin et al. · Journal of Clinical Investigation Open access 19 Jan 2010 997
18 Recurrence Rates after Treatment of Breast Cancer with Standard Radiotherapy with or without Additional Radiation Harry G M M Bartelink, Jean-Claude Horiot, Philip M. Poortmans et al. · New England Journal of Medicine 8 Nov 2001 954
19 Enterococcus hirae and Barnesiella intestinihominis Facilitate Cyclophosphamide-Induced Therapeutic Immunomodulatory Effects Romain Daillère et al. · Immunity Open access Oct 2016 888
20 Delineation of the neck node levels for head and neck tumors: A 2013 update. DAHANCA, EORTC, HKNPCSG, NCIC CTG, NCRI, RTOG, TROG consensus guidelines Vincent Grégoire, Kian K Ang, Wilfried Budach et al. · Radiotherapy and Oncology Nov 2013 871
21 Consensus guidelines for the detection of immunogenic cell death Oliver Kepp et al. · OncoImmunology Open access 2 Sep 2014 842
22 Abiraterone plus prednisone added to androgen deprivation therapy and docetaxel in de novo metastatic castration-sensitive prostate cancer (PEACE-1): a multicentre, open-label, randomised, phase 3 study with a 2 × 2 factorial design Karim S. Fizazi et al. · The Lancet Open access Apr 2022 823
23 Chemotherapy-triggered cathepsin B release in myeloid-derived suppressor cells activates the Nlrp3 inflammasome and promotes tumor growth Mélanie Bruchard, Grégoire Mignot, Valentin Dérangère et al. · Nature Medicine 2 Dec 2012 795
24 Androgen-deprivation therapy alone or with docetaxel in non-castrate metastatic prostate cancer (GETUG-AFU 15): a randomised, open-label, phase 3 trial Gwénaëlle Gravis et al. · The Lancet Oncology 8 Jan 2013 747
25 Predictive value of grade for metastasis development in the main histologic types of adult soft tissue sarcomas Jean‐Michel Coindre, Philippe Terrier, Louis Guillou et al. · Cancer 2001 744
26 Fluorouracil-based adjuvant chemotherapy after preoperative chemoradiotherapy in rectal cancer: long-term results of the EORTC 22921 randomised study Jean-François Bosset, G. Calais, Laurent Mineur et al. · The Lancet Oncology 16 Jan 2014 741
27 Hybrid Minimally Invasive Esophagectomy for Esophageal Cancer C. Mariette, Sheraz Rehan Markar, Tienhan Sandrine Dabakuyo‐Yonli et al. · New England Journal of Medicine 9 Jan 2019 738
28 Phase III trial comparing intensive induction chemoradiotherapy (60 Gy, infusional 5-FU and intermittent cisplatin) followed by maintenance gemcitabine with gemcitabine alone for locally advanced unresectable pancreatic cancer. Definitive results of the 2000–01 FFCD/SFRO study Bruno Chauffert, F. Mornex, F. Bonnetain et al. · Annals of Oncology Open access 9 May 2008 699
29 Whole-breast irradiation with or without a boost for patients treated with breast-conserving surgery for early breast cancer: 20-year follow-up of a randomised phase 3 trial Harry G M M Bartelink et al. · The Lancet Oncology Open access 8 Dec 2014 696
30 Intestinal Akkermansia muciniphila predicts clinical response to PD-1 blockade in patients with advanced non-small-cell lung cancer Lisa Derosa et al. · Nature Medicine Open access Feb 2022 684
31 Hyperfractionation versus conventional fractionation in oropharyngeal carcinoma: final analysis of a randomized trial of the EORTC cooperative group of radiotherapy Jean-Claude Horiot, René Le Fur, T. Nguyen et al. · Radiotherapy and Oncology Dec 1992 684
32 Five-Year Outcomes From the Randomized, Phase III Trials CheckMate 017 and 057: Nivolumab Versus Docetaxel in Previously Treated Non–Small-Cell Lung Cancer Hossein Borghaei et al. · Journal of Clinical Oncology Open access 15 Jan 2021 683
33 CT-based delineation of organs at risk in the head and neck region: DAHANCA, EORTC, GORTEC, HKNPCSG, NCIC CTG, NCRI, NRG Oncology and TROG consensus guidelines Charlotte L. Brouwer, Roel J.H.M. Steenbakkers, Jean Bourhis et al. · Radiotherapy and Oncology Open access 13 Aug 2015 667
34 A European Organisation for Research and Treatment of Cancer Phase III Trial of Adjuvant Whole-Brain Radiotherapy Versus Observation in Patients With One to Three Brain Metastases From Solid Tumors After Surgical Resection or Radiosurgery: Quality-of-Life Results Riccardo Soffietti, Martin Köcher, Ufuk Abacıoğlu et al. · Journal of Clinical Oncology Open access 4 Dec 2012 648
35 Definition of the prostate in CT and MRI: a multi-observer study Coen R. N. Rasch, I. Barillot, Peter Remeijer et al. · International Journal of Radiation Oncology*Biology*Physics 1999 567
36 Intestinal microbiota contributes to individual susceptibility to alcoholic liver disease Marta Llopis et al. · Gut 7 Dec 2015 566
37 Caloric Restriction Mimetics Enhance Anticancer Immunosurveillance Federico Pietrocola et al. · Cancer Cell Open access Jul 2016 554
38 Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer Australian Cancer Study et al. · Nature Genetics Open access443 authors 27 Mar 2013 544
39 Gemcitabine and Oxaliplatin Chemotherapy or Surveillance in Resected Biliary Tract Cancer (PRODIGE 12-ACCORD 18-UNICANCER GI): A Randomized Phase III Study Julien Edeline et al. · Journal of Clinical Oncology Feb 2019 543
40 Trastuzumab-based treatment of HER2-positive breast cancer: an antibody-dependent cellular cytotoxicity mechanism? Laurent Arnould, M Gelly, Frederique Madeleine Penault-Llorca et al. · British Journal of Cancer Open access 2006 539
41 Accelerated fractionation (AF) compared to conventional fractionation (CF) improves loco-regional control in the radiotherapy of advanced head and neck cancers: results of the EORTC 22851 randomized trial Jean-Claude Horiot, Patrick Bontemps, Walter Van den Bogaert et al. · Radiotherapy and Oncology Aug 1997 508
42 Validated prediction of clinical outcome in sarcomas and multiple types of cancer on the basis of a gene expression signature related to genome complexity Frédéric Chibon, Pauline Lagarde, Sébastien Salas et al. · Nature Medicine 27 Jun 2010 480
43 Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer ABCTB Investigators et al. · Nature Genetics Open access476 authors 23 Oct 2017 477
44 Classification of current anticancer immunotherapies Lorenzo Galluzzi et al. · Oncotarget Open access 18 Dec 2014 475
45 Nivolumab versus docetaxel in previously treated advanced non-small-cell lung cancer (CheckMate 017 and CheckMate 057): 3-year update and outcomes in patients with liver metastases E.E. Vokes et al. · Annals of Oncology Open access Feb 2018 474
46 Radiotherapy and Immunogenic Cell Death Encouse B. Golden, Lionel Apétoh · Seminars in Radiation Oncology Open access 3 Dec 2014 464
47 70 Gy Versus 80 Gy in Localized Prostate Cancer: 5-Year Results of GETUG 06 Randomized Trial V. Beckendorf, Stephane Gilles Guerif, É. Le Prisé et al. · International Journal of Radiation Oncology*Biology*Physics 15 Dec 2010 459
48 Definitive chemoradiotherapy with FOLFOX versus fluorouracil and cisplatin in patients with oesophageal cancer (PRODIGE5/ACCORD17): final results of a randomised, phase 2/3 trial Thierry Conroy, Marie‐Pierre Galais, Jean‐Luc Raoul et al. · The Lancet Oncology 17 Feb 2014 455
49 Patients With Curative Resection of cT3-4 Rectal Cancer After Preoperative Radiotherapy or Radiochemotherapy: Does Anybody Benefit From Adjuvant Fluorouracil-Based Chemotherapy? A Trial of the European Organisation for Research and Treatment of Cancer Radiation Oncology Group Laurence Collette, Jean-François Bosset, Marcel den Dulk et al. · Journal of Clinical Oncology 28 Sep 2007 453
50 Chemotherapy-induced antitumor immunity requires formyl peptide receptor 1 Erika Vacchelli et al. · Science 29 Oct 2015 449

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.