| 1 |
FOLFIRINOX versus Gemcitabine for Metastatic Pancreatic Cancer
Thierry Conroy, Françoise Desseigne, Marc Ychou et al. · New England Journal of Medicine
Open access |
11 May 2011 |
7,927 |
| 2 |
Erlotinib versus standard chemotherapy as first-line treatment for European patients with advanced EGFR mutation-positive non-small-cell lung cancer (EURTAC): a multicentre, open-label, randomised phase 3 trial
Rafael Rosell et al. · The Lancet Oncology
Open access |
30 Jan 2012 |
5,563 |
| 3 |
Postoperative Irradiation with or without Concomitant Chemotherapy for Locally Advanced Head and Neck Cancer
Jacques Bernier, Christian Domenge, Mahmut Özsahin et al. · New England Journal of Medicine
Open access |
5 May 2004 |
3,214 |
| 4 |
Efficacy of Pembrolizumab in Patients With Noncolorectal High Microsatellite Instability/Mismatch Repair–Deficient Cancer: Results From the Phase II KEYNOTE-158 Study
Aurélien Marabelle et al. · Journal of Clinical Oncology
Open access |
4 Nov 2019 |
3,072 |
| 5 |
Regorafenib monotherapy for previously treated metastatic colorectal cancer (CORRECT): an international, multicentre, randomised, placebo-controlled, phase 3 trial
Axel F. Grothey, Eric Van Cutsem, Alberto Felice Sobrero et al. · The Lancet
|
21 Nov 2012 |
2,934 |
| 6 |
EANO guidelines on the diagnosis and treatment of diffuse gliomas of adulthood
Michael Weller et al. · Nature Reviews Clinical Oncology
ReviewOpen access |
8 Dec 2020 |
2,063 |
| 7 |
Radiotherapy or surgery of the axilla after a positive sentinel node in breast cancer (EORTC 10981-22023 AMAROS): a randomised, multicentre, open-label, phase 3 non-inferiority trial
Mila Donker et al. · The Lancet Oncology
Open access |
15 Oct 2014 |
1,891 |
| 8 |
Defining risk levels in locally advanced head and neck cancers: A comparative analysis of concurrent postoperative radiation plus chemotherapy trials of the EORTC (#22931) and RTOG (# 9501)
Jacques Bernier, Jay Scott Cooper, Thomas F. Pajak et al. · Head & Neck
|
2005 |
1,782 |
| 9 |
Cisplatin, Fluorouracil, and Docetaxel in Unresectable Head and Neck Cancer
Jan Baptist Vermorken, Éva Remenár, Carla van Herpen et al. · New England Journal of Medicine
Open access |
24 Oct 2007 |
1,726 |
| 10 |
Larynx Preservation in Pyriform Sinus Cancer: Preliminary Results of a European Organization for Research and Treatment of Cancer Phase III Trial
J.-L. Lefebvre, Dominique Chevalier, Bernard Luboinski et al. · JNCI Journal of the National Cancer Institute
|
3 Jul 1996 |
1,340 |
| 11 |
Glioblastoma in adults: a Society for Neuro-Oncology (SNO) and European Society of Neuro-Oncology (EANO) consensus review on current management and future directions
Patrick Yung Wen et al. · Neuro-Oncology
Open access |
20 Apr 2020 |
1,183 |
| 12 |
Prognostic value of tumor oxygenation in 397 head and neck tumors after primary radiation therapy. An international multi-center study
Marianne Nordsmark, Søren Møller Bentzen, Volker Rudat et al. · Radiotherapy and Oncology
|
12 Aug 2005 |
953 |
| 13 |
Morphine and alternative opioids in cancer pain: the EAPC recommendations
G.W. Hanks, Franco De Conno, Nathan I. Cherny et al. · British Journal of Cancer
Open access |
2001 |
861 |
| 14 |
Dendritic cell-derived exosomes as maintenance immunotherapy after first line chemotherapy in NSCLC
Benjamin Besse et al. · OncoImmunology
Open access |
12 Aug 2015 |
809 |
| 15 |
Carbon monoxide poisoning — a public health perspective
James A. Raub, Monique Mathieu-Nolf, Neil B. Hampson et al. · Toxicology
|
Apr 2000 |
806 |
| 16 |
A phase II study
Philippe Rougier, Antoine Adenis, Michel Pierre Ducreux et al. · European Journal of Cancer
|
May 2000 |
752 |
| 17 |
Lapatinib plus capecitabine in patients with previously untreated brain metastases from HER2-positive metastatic breast cancer (LANDSCAPE): a single-group phase 2 study
Thomas Bachelot, Gilles Romieu, Mario Campone et al. · The Lancet Oncology
|
Nov 2012 |
748 |
| 18 |
Predictive value of grade for metastasis development in the main histologic types of adult soft tissue sarcomas
Jean‐Michel Coindre, Philippe Terrier, Louis Guillou et al. · Cancer
|
2001 |
744 |
| 19 |
EANO–ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up of patients with leptomeningeal metastasis from solid tumours
Émilie Le Rhun, Michael Weller, Dieta Brandsma et al. · Annals of Oncology
Open access |
5 May 2017 |
649 |
| 20 |
Squamous cell carcinoma of the head and neck: EHNS–ESMO–ESTRO Clinical Practice Guidelines for diagnosis, treatment and follow-up
Vincent Grégoire, J. -L. Lefebvre, Lisa Francesca Licitra et al. · Annals of Oncology
Open access |
May 2010 |
624 |
| 21 |
First-line rituximab combined with short-term prednisone versus prednisone alone for the treatment of pemphigus (Ritux 3): a prospective, multicentre, parallel-group, open-label randomised trial
P. Joly et al. · The Lancet
|
22 Mar 2017 |
622 |
| 22 |
Screening for Vulnerability in Older Cancer Patients: The ONCODAGE Prospective Multicenter Cohort Study
Pierre Soubeyran, Carine A. Bellera, Jean Goyard et al. · PLoS ONE
Open access |
11 Dec 2014 |
601 |
| 23 |
Carboplatin and weekly paclitaxel doublet chemotherapy compared with monotherapy in elderly patients with advanced non-small-cell lung cancer: IFCT-0501 randomised, phase 3 trial
Élisabeth Quoix et al. · The Lancet
|
13 Aug 2011 |
578 |
| 24 |
Anastrozole is superior to tamoxifen as first-line therapy in hormone receptor positive advanced breast carcinoma
Jacques Bonneterre, Aman U. Buzdar, Jean‐Marc Nabholtz et al. · Cancer
|
2001 |
576 |
| 25 |
Effect of the MDM2 antagonist RG7112 on the P53 pathway in patients with MDM2-amplified, well-differentiated or dedifferentiated liposarcoma: an exploratory proof-of-mechanism study
Isabelle Ray‐Coquard, Jean‐Yves Blay, Antoîne Italiano et al. · The Lancet Oncology
|
16 Oct 2012 |
575 |
| 26 |
Detection rate and diagnostic accuracy of sentinel-node biopsy in early stage endometrial cancer: a prospective multicentre study (SENTI-ENDO)
Marcos Ballester, Gil Dubernard, Fabrice R Lecuru et al. · The Lancet Oncology
|
13 Apr 2011 |
574 |
| 27 |
Intestinal microbiota contributes to individual susceptibility to alcoholic liver disease
Marta Llopis et al. · Gut
|
7 Dec 2015 |
566 |
| 28 |
Trastuzumab-based treatment of HER2-positive breast cancer: an antibody-dependent cellular cytotoxicity mechanism?
Laurent Arnould, M Gelly, Frederique Madeleine Penault-Llorca et al. · British Journal of Cancer
Open access |
2006 |
539 |
| 29 |
Nivolumab Combination Therapy in Advanced Esophageal Squamous-Cell Carcinoma
Yuichiro� Doki et al. · UCL Discovery (University College London)
Open access |
3 Feb 2022 |
532 |
| 30 |
Efficacy and Safety of Pembrolizumab for Heavily Pretreated Patients With Advanced, Metastatic Adenocarcinoma or Squamous Cell Carcinoma of the Esophagus
Manish A. Shah, Takashi Kojima, Daniel Hochhauser et al. · JAMA Oncology
Open access |
20 Dec 2018 |
524 |
| 31 |
Association of Type and Location ofBRCA1andBRCA2Mutations With Risk of Breast and Ovarian Cancer
Timothy R. Rebbeck et al. · JAMA
Open access258 authors |
7 Apr 2015 |
517 |
| 32 |
The management of desmoid tumours: A joint global consensus-based guideline approach for adult and paediatric patients
Ben Alman et al. · European Journal of Cancer
Open access |
28 Jan 2020 |
508 |
| 33 |
Impact of FOLFIRINOX Compared With Gemcitabine on Quality of Life in Patients With Metastatic Pancreatic Cancer: Results From the PRODIGE 4/ACCORD 11 Randomized Trial
S. Gourgou-Bourgade, Caroline Mollévi, Françoise Desseigne et al. · Journal of Clinical Oncology
Open access |
4 Dec 2012 |
507 |
| 34 |
Overall survival in the OlympiA phase III trial of adjuvant olaparib in patients with germline pathogenic variants in BRCA1/2 and high-risk, early breast cancer
Charles E. Geyer et al. · Annals of Oncology
Open access609 authors |
10 Oct 2022 |
477 |
| 35 |
Pembrolizumab in microsatellite instability high or mismatch repair deficient cancers: updated analysis from the phase II KEYNOTE-158 study
Michele Maio, Paolo A. Ascierto, L. V. Manzyuk et al. · Annals of Oncology
Open access |
6 Jun 2022 |
471 |
| 36 |
Pregnancy-Associated Hemolytic Uremic Syndrome Revisited in the Era of Complement Gene Mutations
Fádi Fakhouri, Lubka T. Roumenina, François Provôt et al. · Journal of the American Society of Nephrology
Open access |
4 Mar 2010 |
469 |
| 37 |
ERBB2 oncogene in human breast cancer and its clinical significance
Françoise Révillion, Jacques M Bonneterre, Jean‐Philippe Peyrat · European Journal of Cancer
|
May 1998 |
458 |
| 38 |
Definitive chemoradiotherapy with FOLFOX versus fluorouracil and cisplatin in patients with oesophageal cancer (PRODIGE5/ACCORD17): final results of a randomised, phase 2/3 trial
Thierry Conroy, Marie‐Pierre Galais, Jean‐Luc Raoul et al. · The Lancet Oncology
|
17 Feb 2014 |
455 |
| 39 |
Depression, quality of life and breast cancer: a review of the literature
Michel Reich, A. Lesur, C. Perdrizet-Chevallier · Breast Cancer Research and Treatment
|
2 Aug 2007 |
446 |
| 40 |
Pembrolizumab After Two or More Lines of Previous Therapy in Patients With Recurrent or Metastatic SCLC: Results From the KEYNOTE-028 and KEYNOTE-158 Studies
Hyun Cheol Chung et al. · Journal of Thoracic Oncology
Open access |
20 Dec 2019 |
445 |
| 41 |
Immune-checkpoint inhibitors associated with interstitial lung disease in cancer patients
Myriam Delaunay et al. · European Respiratory Journal
Open access |
Aug 2017 |
427 |
| 42 |
Induction Chemotherapy Followed by Either Chemoradiotherapy or Bioradiotherapy for Larynx Preservation: The TREMPLIN Randomized Phase II Study
Jean Louis Lefèbvre et al. · Journal of Clinical Oncology
Open access |
23 Jan 2013 |
422 |
| 43 |
An update on the management of sporadic desmoid-type fibromatosis: a European Consensus Initiative between Sarcoma PAtients EuroNet (SPAEN) and European Organization for Research and Treatment of Cancer (EORTC)/Soft Tissue and Bone Sarcoma Group (STBSG)
B. Kasper et al. · Annals of Oncology
Open access |
22 Jun 2017 |
419 |
| 44 |
Comparative genomic hybridisation array and DNA sequencing to direct treatment of metastatic breast cancer: a multicentre, prospective trial (SAFIR01/UNICANCER)
Fabrice André, Thomas Bachelot, Frédéric Commo et al. · The Lancet Oncology
|
6 Feb 2014 |
418 |
| 45 |
Mutational Profile of Metastatic Breast Cancers: A Retrospective Analysis
Céline Lefèbvre et al. · PLoS Medicine
Open access |
27 Dec 2016 |
413 |
| 46 |
Use of PD-1 Targeting, Macrophage Infiltration, and IDO Pathway Activation in Sarcomas
Maud Toulmonde, Nicolas Penel, Julien Adam et al. · JAMA Oncology
Open access |
29 Jun 2017 |
408 |
| 47 |
Organ preservation for rectal cancer (GRECCAR 2): a prospective, randomised, open-label, multicentre, phase 3 trial
Éric Rullier, Philippe Rouanet, Jean‐Jacques Tuech et al. · The Lancet
|
8 Jun 2017 |
393 |
| 48 |
Meta-analysis of chemotherapy in head and neck cancer (MACH-NC): An update on 107 randomized trials and 19,805 patients, on behalf of MACH-NC Group
Benjamin Lacas et al. · Radiotherapy and Oncology
ReviewOpen access105 authors |
27 Jan 2021 |
391 |
| 49 |
Radiotherapy or Surgery of the Axilla After a Positive Sentinel Node in Breast Cancer: 10-Year Results of the Randomized Controlled EORTC 10981-22023 AMAROS Trial
Sanne A. L. Bartels et al. · Journal of Clinical Oncology
Open access |
16 Nov 2022 |
389 |
| 50 |
Improved survival using specialized multidisciplinary board in sarcoma patients
Jean‐Yves Blay et al. · Annals of Oncology
Open access |
25 Aug 2017 |
382 |