Most cited papers from Children's Cancer Center

Children's Cancer Center

What are the most cited papers from Children's Cancer Center?

The most cited paper from Children's Cancer Center is "The repertoire of mutational signatures in human cancer" (Ludmil B. Alexandrov et al., 2020), with 3,854 citations. Next come "Genomic analyses identify molecular subtypes of pancreatic cancer" (3,805) and "Stromal Fibroblasts Present in Invasive Human Breast Carcinomas Promote Tumor Growth and Angiogenesis through Elevated SDF-1/CXCL12 Secretion" (3,791).

Published TypeFieldAccessAuthorsCitations

Showing 50 of 60 papers. Every paper with more than 469 citations is listed.

Most cited papers, sortable by citations and release date
#	Paper
1	The repertoire of mutational signatures in human cancer Ludmil B. Alexandrov et al. · Nature Open access1,384 authors	5 Feb 2020	3,854
2	Genomic analyses identify molecular subtypes of pancreatic cancer Peter J. Bailey et al. · Nature 103 authors	23 Feb 2016	3,805
3	Stromal Fibroblasts Present in Invasive Human Breast Carcinomas Promote Tumor Growth and Angiogenesis through Elevated SDF-1/CXCL12 Secretion Akira Orimo, Piyush B. Gupta, Dennis C. Sgroi et al. · Cell Open access	May 2005	3,791
4	Comprehensive molecular characterization of clear cell renal cell carcinoma Chad J. Creighton et al. · Nature Open access292 authors	23 Jun 2013	3,603
5	Molecular subgroups of medulloblastoma: the current consensus Michael D. Taylor, Paul A. Northcott, Andrey Korshunov et al. · Acta Neuropathologica Open access	2 Dec 2011	1,993
6	Technical standards for the interpretation and reporting of constitutional copy-number variants: a joint consensus recommendation of the American College of Medical Genetics and Genomics (ACMG) and the Clinical Genome Resource (ClinGen) Erin Rooney Riggs, Erica Andersen, Athena M. Cherry et al. · Genetics in Medicine Open access	5 Nov 2019	1,854
7	Intrinsic Resistance of Tumorigenic Breast Cancer Cells to Chemotherapy X. Li, Michael T. Lewis, Jian Huang et al. · JNCI Journal of the National Cancer Institute Open access	29 Apr 2008	1,806
8	Revised classification of histiocytoses and neoplasms of the macrophage-dendritic cell lineages Jean‐François Emile et al. · Blood Open access	10 Mar 2016	1,603
9	Comprehensive Genomic Analysis Identifies Novel Subtypes and Targets of Triple-Negative Breast Cancer Matthew D. Burstein, Anna I. Tsimelzon, Graham M. Poage et al. · Clinical Cancer Research Open access	11 Sep 2014	1,430
10	Residual breast cancers after conventional therapy display mesenchymal as well as tumor-initiating features Chad J. Creighton et al. · Proceedings of the National Academy of Sciences Open access	3 Aug 2009	1,397
11	Global signatures of protein and mRNA expression levels Raquel de Sousa Abreu, Luiz O. F. Penalva, Edward M. Marcotte et al. · Molecular BioSystems Open access	Oct 2009	1,289
12	Virus-specific T cells engineered to coexpress tumor-specific receptors: persistence and antitumor activity in individuals with neuroblastoma Martin Pulé, Barbara Savoldo, Gary D. Myers et al. · Nature Medicine Open access	Nov 2008	1,200
13	Antitumor activity and long-term fate of chimeric antigen receptor–positive T cells in patients with neuroblastoma Chrystal Ursula Louis, Barbara Savoldo, Gianpietro Dotti et al. · Blood Open access	8 Oct 2011	1,181
14	How I treat hemophagocytic lymphohistiocytosis Michael B. Jordan, Carl E. Allen, Sheila S Weitzman et al. · Blood Open access	10 Aug 2011	1,160
15	All-trans-Retinoic Acid in Acute Promyelocytic Leukemia Martin S. Tallman, Janet W. Andersen, Charles Alan Schiffer et al. · New England Journal of Medicine	9 Oct 1997	1,099
16	The Somatic Genomic Landscape of Chromophobe Renal Cell Carcinoma Caleb Davis et al. · Cancer Cell Open access273 authors	21 Aug 2014	872
17	Novel mutations target distinct subgroups of medulloblastoma Giles W Robinson et al. · Nature Open access	19 Jun 2012	869
18	HER2-Specific Chimeric Antigen Receptor–Modified Virus-Specific T Cells for Progressive Glioblastoma Nabil M. Ahmed et al. · JAMA Oncology Open access	20 Apr 2017	854
19	Clinical significance of minimal residual disease in childhood acute lymphoblastic leukemia and its relationship to other prognostic factors: a Children's Oncology Group study Michael J. Borowitz, Meenakshi Devidas, Stephen P. Hunger et al. · Blood Open access	4 Apr 2008	849
20	MicroRNA-34a functions as a potential tumor suppressor by inducing apoptosis in neuroblastoma cells Carrie L. Welch, Y Chen, Raymond L. Stallings · Oncogene	12 Feb 2007	814
21	Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes James McKay et al. · Nature Genetics Open access140 authors	12 Jun 2017	808
22	Resolution of Disease Phenotypes Resulting from Multilocus Genomic Variation Jennifer Ellen Posey et al. · New England Journal of Medicine Open access	7 Dec 2016	807
23	NF-κB and STAT3 signaling pathways collaboratively link inflammation to cancer Yihui Fan, Renfang Mao, Jianhua Yang · Protein & Cell Open access	Mar 2013	801
24	Genome-wide association study identifies five susceptibility loci for glioma Sanjay S. Shete et al. · Nature Genetics Open access	5 Jul 2009	798
25	Long-term outcome of EBV-specific T-cell infusions to prevent or treat EBV-related lymphoproliferative disease in transplant recipients Helen Elisabeth Heslop, Karen S. Slobod, Martin Pulé et al. · Blood Open access	30 Oct 2009	784
26	A brief history of human disease genetics Melina Claussnitzer, Judy H. Cho, Rory Collins et al. · Nature Open access	8 Jan 2020	760
27	Closely related T-memory stem cells correlate with in vivo expansion of CAR.CD19-T cells and are preserved by IL-7 and IL-15 Yang Xu, Ming Zhang, Carlos A. Ramos et al. · Blood Open access	29 Apr 2014	756
28	Integrative Genomic Analysis of Medulloblastoma Identifies a Molecular Subgroup That Drives Poor Clinical Outcome Yoon-Jae Cho, Aviad Tsherniak, Pablo Tamayo et al. · Journal of Clinical Oncology Open access	23 Nov 2010	729
29	Functionally defined therapeutic targets in diffuse intrinsic pontine glioma Catherine S. Grasso et al. · Nature Medicine Open access	4 May 2015	727
30	The Genetic Landscape of the Childhood Cancer Medulloblastoma Donald Williams Parsons et al. · Science Open access	16 Dec 2010	726
31	Safety and activity of crizotinib for paediatric patients with refractory solid tumours or anaplastic large-cell lymphoma: a Children's Oncology Group phase 1 consortium study Yaël P. Mossé, Megan S. Lim, Stephan D. Voss et al. · The Lancet Oncology Open access	17 Apr 2013	714
32	A Comprehensive Pan-Cancer Molecular Study of Gynecologic and Breast Cancers Ashton C. Berger et al. · Cancer Cell Open access773 authors	Apr 2018	702
33	Confirmed efficacy of etoposide and dexamethasone in HLH treatment: long-term results of the cooperative HLH-2004 study Elisabet Bergsten, AnnaCarin Horne, Maurizio Aricò et al. · Blood Open access	21 Sep 2017	682
34	Tandem CAR T cells targeting HER2 and IL13Rα2 mitigate tumor antigen escape Meenakshi G. Hegde et al. · Journal of Clinical Investigation Open access	17 Jul 2016	682
35	miR-33a/b contribute to the regulation of fatty acid metabolism and insulin signaling Alberto Dávalos, Leigh Goedeke, Peter Smibert et al. · Proceedings of the National Academy of Sciences Open access	16 May 2011	669
36	Mutation as a Stress Response and the Regulation of Evolvability Rodrigo S. Galhardo, P. J. Hastings, Susan M. Rosenberg · Critical Reviews in Biochemistry and Molecular Biology ReviewOpen access	2007	663
37	Consensus recommendations for the diagnosis and clinical management of Rosai-Dorfman-Destombes disease Oussama Abla, Eric D. Jacobsen, Jennifer Lee Picarsic et al. · Blood Open access	2 May 2018	644
38	Sequence signatures and mRNA concentration can explain two‐thirds of protein abundance variation in a human cell line Christine Vogel, Raquel de Sousa Abreu, Daijin Ko et al. · Molecular Systems Biology Open access	24 Aug 2010	637
39	NCCN Task Force Report: Management of Patients with Gastrointestinal Stromal Tumor (GIST)—Update of the NCCN Clinical Practice Guidelines George D. Demetri et al. · Journal of the National Comprehensive Cancer Network	May 2007	637
40	Widespread deregulation of microRNA expression in human prostate cancer Mustafa Özen, Chad J. Creighton, Emre Özdemir et al. · Oncogene	24 Sep 2007	636
41	Detectable clonal mosaicism and its relationship to aging and cancer Kevin B. Jacobs et al. · Nature Genetics Open access189 authors	6 May 2012	605
42	Outcome of Treatment in Children with Philadelphia Chromosome–Positive Acute Lymphoblastic Leukemia Maurizio Aricò et al. · New England Journal of Medicine Open access	6 Apr 2000	601
43	Consensus guidelines for the diagnosis and clinical management of Erdheim-Chester disease Eli L. Diamond, Lorenzo Dagna, David Michael Hyman et al. · Blood Open access	22 May 2014	591
44	Minimal residual disease-directed therapy for childhood acute myeloid leukaemia: results of the AML02 multicentre trial Jeffrey E. Rubnitz, Hiroto Inaba, Gary Van Houten Dahl et al. · The Lancet Oncology Open access	6 May 2010	588
45	Langerhans-Cell Histiocytosis Carl E. Allen, Miriam Mérad, Kenneth L. McClain · New England Journal of Medicine Open access	29 Aug 2018	577
46	Comparison of MAPIE versus MAP in patients with a poor response to preoperative chemotherapy for newly diagnosed high-grade osteosarcoma (EURAMOS-1): an open-label, international, randomised controlled trial Neyssa M. Marina et al. · The Lancet Oncology Open access	31 Aug 2016	559
47	Crosstalk between the Estrogen Receptor and the HER Tyrosine Kinase Receptor Family: Molecular Mechanism and Clinical Implications for Endocrine Therapy Resistance Grazia Arpino, Lisa Wiechmann, Charles Kent Osborne et al. · Endocrine Reviews Open access	23 Jan 2008	554
48	Identification of diverse astrocyte populations and their malignant analogs Chia-Ching John Lin, Kwanha Yu, Asante Hatcher et al. · Nature Neuroscience Open access	6 Feb 2017	550
49	CAR T Cells Administered in Combination with Lymphodepletion and PD-1 Inhibition to Patients with Neuroblastoma Andras Attila Heczey, Chrystal Ursula Louis, Barbara Savoldo et al. · Molecular Therapy Open access	9 Jun 2017	542
50	ARID1A Deficiency Impairs the DNA Damage Checkpoint and Sensitizes Cells to PARP Inhibitors Jianfeng Shen, Yang Peng, Leizhen Wei et al. · Cancer Discovery Open access	11 Jun 2015	540

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.