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Most cited papers from CIC bioGUNE

What are the most cited papers from CIC bioGUNE?

The most cited paper from CIC bioGUNE is "Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines" (Clotilde Théry et al., 2018), with 11,535 citations. Next come "Biological properties of extracellular vesicles and their physiological functions" (6,130) and "Minimal information for studies of extracellular vesicles (MISEV2023): From basic to advanced approaches" (4,377).

Showing 50 of 61 papers. Every paper with more than 222 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines Clotilde Théry et al. · Journal of Extracellular Vesicles Open access382 authors 23 Nov 2018 11,535
2 Biological properties of extracellular vesicles and their physiological functions María Yáñez‐Mó et al. · Journal of Extracellular Vesicles Open access 2015 6,130
3 Minimal information for studies of extracellular vesicles (MISEV2023): From basic to advanced approaches Joshua A Welsh et al. · Journal of Extracellular Vesicles Open access Feb 2024 4,377
4 Large-scale cis- and trans-eQTL analyses identify thousands of genetic loci and polygenic scores that regulate blood gene expression Urmo Võsa et al. · Nature Genetics Open access114 authors Sep 2021 2,339
5 Applying extracellular vesicles based therapeutics in clinical trials – an ISEV position paper Thomas Lener et al. · Journal of Extracellular Vesicles Open access 2015 1,591
6 Vesiclepedia: A Compendium for Extracellular Vesicles with Continuous Community Annotation Hina Kalra et al. · PLoS Biology Open access 18 Dec 2012 1,391
7 Cancer metabolism: fatty acid oxidation in the limelight Arkaitz Carracedo, Lewis C. Cantley, Pier Paolo Pandolfi · Nature reviews. Cancer ReviewOpen access 28 Feb 2013 1,356
8 c-Jun Reprograms Schwann Cells of Injured Nerves to Generate a Repair Cell Essential for Regeneration Peter Arthur‐Farraj, Morwena Latouche, Daniel K. Wilton et al. · Neuron Open access Aug 2012 894
9 Sustained proliferation in cancer: Mechanisms and novel therapeutic targets Mark A. Feitelson et al. · Seminars in Cancer Biology Open access 17 Apr 2015 794
10 SIRT3 Opposes Reprogramming of Cancer Cell Metabolism through HIF1α Destabilization Lydia W.S. Finley, Arkaitz Carracedo, Jaewon James Lee et al. · Cancer Cell Open access Mar 2011 793
11 Characterization and Comprehensive Proteome Profiling of Exosomes Secreted by Hepatocytes Javier Conde‐Vancells, Eva Rodríguez‐Suárez, Nieves Embade et al. · Journal of Proteome Research Open access 11 Nov 2008 665
12 Increased Fibroblast Growth Factor 21 in Obesity and Nonalcoholic Fatty Liver Disease Jody R. Dushay, Patricia C. Chui, Gosala S. Gopalakrishnan et al. · Gastroenterology Open access 6 May 2010 608
13 S-adenosylmethionine in Liver Health, Injury, and Cancer Shelly Chi-Loo Lu, José María Mato · Physiological Reviews ReviewOpen access Oct 2012 567
14 Efficient protection and isolation of ubiquitylated proteins using tandem ubiquitin‐binding entities Roland Hjerpe, Fabienne Aillet, Fernando Lopitz‐Otsoa et al. · EMBO Reports Open access 2 Oct 2009 520
15 Schwann cell autophagy, myelinophagy, initiates myelin clearance from injured nerves Jose Antonio Gomez-Sanchez et al. · The Journal of Cell Biology Open access 6 Jul 2015 481
16 Metabolomics and lipidomics in NAFLD: biomarkers and non-invasive diagnostic tests Mojgan Masoodi, Amalia Gastaldelli, Tuulia Hyötyläinen et al. · Nature Reviews Gastroenterology & Hepatology Review 10 Sep 2021 464
17 Senescence atlas reveals an aged-like inflamed niche that blunts muscle regeneration Victoria Moiseeva et al. · Nature Open access 21 Dec 2022 420
18 Urinary extracellular vesicles: A position paper by the Urine Task Force of the International Society for Extracellular Vesicles Uta Erdbrügger et al. · Journal of Extracellular Vesicles Open access May 2021 420
19 Quiescence Modulates Stem Cell Maintenance and Regenerative Capacity in the Aging Brain Georgios Kalamakis et al. · Cell Open access 28 Feb 2019 418
20 Methods for Separation and Characterization of Extracellular Vesicles: Results of a Worldwide Survey Performed by the ISEV Rigor and Standardization Subcommittee Félix Royo, Clotilde Théry, Juan Manuel Falcón‐Pérez et al. · Cells Open access 25 Aug 2020 404
21 WNT signalling in prostate cancer Virginia Murillo-Garzón, Robert M. Kypta · Nature Reviews Urology Review 12 Sep 2017 387
22 Updating MISEV: Evolving the minimal requirements for studies of extracellular vesicles Kenneth Whitaker Witwer, Deborah C. I. Goberdhan, Lorraine O’Driscoll et al. · Journal of Extracellular Vesicles Open access Dec 2021 370
23 A novel community driven software for functional enrichment analysis of extracellular vesicles data Mohashin Pathan et al. · Journal of Extracellular Vesicles Open access 26 May 2017 369
24 Amyloid β oligomers induce Ca2+ dysregulation and neuronal death through activation of ionotropic glutamate receptors Elena Alberdi, María Victoria Sánchez‐Gómez, Fabio Cavaliere et al. · Cell Calcium Open access 13 Jan 2010 366
25 Sox2 promotes tamoxifen resistance in breast cancer cells Marco Piva, Giacomo Domenici, Oihana Iriondo et al. · EMBO Molecular Medicine Open access 31 Oct 2013 345
26 Improving Protein Expression, Stability, and Function with ProteinMPNN Kiera H. Sumida, Reyes Núñez‐Franco, Indrek Kalvet et al. · Journal of the American Chemical Society Open access 9 Jan 2024 339
27 Mitochondrial Respiration Controls Lysosomal Function during Inflammatory T Cell Responses Francesc Baixauli, Rebeca Acín‐Pérez, Carolina Villarroya‐Beltri et al. · Cell Metabolism Open access 20 Aug 2015 335
28 Using single-vesicle technologies to unravel the heterogeneity of extracellular vesicles Guillermo Bordanaba-Florit, Félix Royo, Sergei G. Kruglik et al. · Nature Protocols 16 Jun 2021 334
29 Rewiring urea cycle metabolism in cancer to support anabolism Rom Keshet, Peter Wojciech Szlosarek, Arkaitz Carracedo et al. · Nature reviews. Cancer Review 7 Sep 2018 328
30 CAR-T Cells Hit the Tumor Microenvironment: Strategies to Overcome Tumor Escape Alba Rodríguez-García, Asís Palazón, Estela Noguera-Ortega et al. · Frontiers in Immunology Open access 17 Jun 2020 323
31 Detection of amyloid fibrils in Parkinson’s disease using plasmonic chirality Jatish Kumar, Hasier Eraña, Elena López‐Martínez et al. · Proceedings of the National Academy of Sciences Open access 12 Mar 2018 314
32 miRanalyzer: a microRNA detection and analysis tool for next-generation sequencing experiments Michael Hackenberg, Martin Sturm, David Langenberger et al. · Nucleic Acids Research Open access 11 May 2009 312
33 Methionine Metabolism and Liver Disease José María Mato, Maria Luz Martínez‐Chantar, Shelly Chi-Loo Lu · Annual Review of Nutrition Review 10 Mar 2008 311
34 Urea Cycle Dysregulation Generates Clinically Relevant Genomic and Biochemical Signatures Joo Sang Lee et al. · Cell Open access 9 Aug 2018 309
35 Magnetic field triggered drug release from polymersomes for cancer therapeutics Hugo Oliveira, Encarnación Pérez-Andrés, Julie Thévenot et al. · Journal of Controlled Release Open access 23 Jan 2013 308
36 Structure Unifies the Viral Universe Nicola G. A. Abrescia, Dennis Henry Bamford, Jonathan M. Grimes et al. · Annual Review of Biochemistry Review 22 May 2012 307
37 Loss of the glycine N‐methyltransferase gene leads to steatosis and hepatocellular carcinoma in mice† Maria Luz Martínez‐Chantar, Mercedes Vázquez–Chantada, Usue Ariz et al. · Hepatology Open access 7 Feb 2008 304
38 Role of S‐adenosyl‐L‐methionine in liver health and injury† José María Mato, Shelly Chi-Loo Lu · Hepatology 26 Apr 2007 303
39 Human PCNA Structure, Function and Interactions Amaia Gonzalez Magaña, Francisco J. Blanco · Biomolecules Open access 8 Apr 2020 295
40 Serum extracellular vesicles contain protein biomarkers for primary sclerosing cholangitis and cholangiocarcinoma Ander Arbelaiz et al. · Hepatology Open access 26 May 2017 293
41 Single-cell analysis of cardiogenesis reveals basis for organ-level developmental defects T. Yvanka de Soysa, Sanjeev S. Ranade, Satoshi Okawa et al. · Nature Open access 24 Jul 2019 289
42 Wnt/β-catenin signalling in prostate cancer Robert M. Kypta, Jonathan Waxman · Nature Reviews Urology Review 19 Jun 2012 279
43 Metabolomic Identification of Subtypes of Nonalcoholic Steatohepatitis Cristina Alonso et al. · Gastroenterology Open access 26 Jan 2017 271
44 Natural and synthetic carbohydrate-based vaccine adjuvants and their mechanisms of action Carlo Pifferi, Roberto González Fuentes, Alberto Fernández‐Tejada · Nature Reviews Chemistry ReviewOpen access 25 Jan 2021 264
45 Glycosylation of extracellular vesicles: current knowledge, tools and clinical perspectives C. B. Williams, Félix Royo, Oier Aizpurua‐Olaizola et al. · Journal of Extracellular Vesicles Open access 4 Mar 2018 262
46 Biological membranes in EV biogenesis, stability, uptake, and cargo transfer: an ISEV position paper arising from the ISEV membranes and EVs workshop Ashley E. Russell et al. · Journal of Extracellular Vesicles Open access 8 Nov 2019 261
47 Salermide, a Sirtuin inhibitor with a strong cancer-specific proapoptotic effect Ester Lara, Antonello Mai, Vincenzo Calvanese et al. · Oncogene 8 Dec 2008 261
48 An unbiased ranking of murine dietary models based on their proximity to human metabolic dysfunction-associated steatotic liver disease (MASLD) Michèle Vacca et al. · Nature Metabolism Open access238 authors 12 Jun 2024 260
49 Correlation between Gene Expression and GO Semantic Similarity Joseph Sevilla, Víctor Segura, Adam Podhorski et al. · IEEE Transactions on Computational Biology and Bioinformatics Oct 2005 249
50 Updating the MISEV minimal requirements for extracellular vesicle studies: building bridges to reproducibility Kenneth Whitaker Witwer et al. · Journal of Extracellular Vesicles Open access 16 Nov 2017 240

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.