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Most cited papers from Clinical Research Institute

What are the most cited papers from Clinical Research Institute?

The most cited paper from Clinical Research Institute is "Rivaroxaban versus Warfarin in Nonvalvular Atrial Fibrillation" (Manesh R. Patel, Kenneth W. Mahaffey, Jyotsna Garg et al., 2011), with 9,484 citations. Next come "Apixaban versus Warfarin in Patients with Atrial Fibrillation" (9,001) and "Ticagrelor versus Clopidogrel in Patients with Acute Coronary Syndromes" (7,154).

Showing 50 of 59 papers. Every paper with more than 1,168 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 Rivaroxaban versus Warfarin in Nonvalvular Atrial Fibrillation Manesh R. Patel, Kenneth W. Mahaffey, Jyotsna Garg et al. · New England Journal of Medicine Open access 10 Aug 2011 9,484
2 Apixaban versus Warfarin in Patients with Atrial Fibrillation Christopher B. Granger et al. · New England Journal of Medicine Open access 28 Aug 2011 9,001
3 Ticagrelor versus Clopidogrel in Patients with Acute Coronary Syndromes Lars C. Wallentin, Richard C. Becker, Andrzej Budaj et al. · New England Journal of Medicine Open access 30 Aug 2009 7,154
4 Staphylococcus aureus Infections: Epidemiology, Pathophysiology, Clinical Manifestations, and Management Steven Y. C. Tong, Joshua Saul Davis, Emily M. Eichenberger et al. · Clinical Microbiology Reviews Open access 27 May 2015 5,276
5 Alirocumab and Cardiovascular Outcomes after Acute Coronary Syndrome Gregory G. Schwartz et al. · New England Journal of Medicine Open access 7 Nov 2018 3,654
6 Genetic variation in IL28B predicts hepatitis C treatment-induced viral clearance Dongliang Ge, Jacques Fellay, Alexander J. V. Thompson et al. · Nature Open access 16 Aug 2009 3,535
7 Recommendations for Conduct, Methodological Practices, and Reporting of Cost-effectiveness Analyses Gillian D Sanders, Peter J. Neumann, Anirban Basu et al. · JAMA Open access 13 Sep 2016 3,113
8 Global, Regional, and National Cancer Incidence, Mortality, Years of Life Lost, Years Lived With Disability, and Disability-Adjusted Life-Years for 29 Cancer Groups, 1990 to 2017 Christina Fitzmaurice et al. · JAMA Oncology Open access628 authors 27 Sep 2019 2,699
9 Effect of Sitagliptin on Cardiovascular Outcomes in Type 2 Diabetes Jennifer B. Green, Mary Angelyn Bethel, Paul W. Armstrong et al. · New England Journal of Medicine Open access 8 Jun 2015 2,619
10 A Randomized Study of the Prevention of Sudden Death in Patients with Coronary Artery Disease Alfred E. Buxton, Kerry L. Lee, John D. Fisher et al. · New England Journal of Medicine Open access 16 Dec 1999 2,500
11 Initial Invasive or Conservative Strategy for Stable Coronary Disease David Joel Maron et al. · New England Journal of Medicine Open access 30 Mar 2020 2,464
12 Telaprevir for Previously Untreated Chronic Hepatitis C Virus Infection Ira M. Jacobson et al. · New England Journal of Medicine Open access 22 Jun 2011 2,394
13 Mayo Clinic Proceedings Sunil V. Rao, James G. Jollis · Mayo Clinic Proceedings Open access Oct 2000 2,231
14 Efficacy and Safety of Exercise Training in Patients With Chronic Heart Failure Christopher M. O’Connor, David J. Whellan, Kerry L. Lee et al. · JAMA Open access 7 Apr 2009 2,197
15 Effects of Once-Weekly Exenatide on Cardiovascular Outcomes in Type 2 Diabetes Rury R. Holman, Mary Angelyn Bethel, Robert John Mentz et al. · New England Journal of Medicine Open access 14 Sep 2017 2,195
16 Early Rhythm-Control Therapy in Patients with Atrial Fibrillation Paulus F. Kirchhof et al. · New England Journal of Medicine Open access 29 Aug 2020 2,193
17 Genetic variation in IL28B and spontaneous clearance of hepatitis C virus David L. Thomas, Chloe L. Thio, Maureen P. Martin et al. · Nature Open access 16 Sep 2009 2,165
18 Radial versus femoral access for coronary angiography and intervention in patients with acute coronary syndromes (RIVAL): a randomised, parallel group, multicentre trial Sanjit S. Jolly, Salim Yusuf, John A. Cairns et al. · The Lancet Apr 2011 2,130
19 Methicillin-resistant Staphylococcus aureus: an overview of basic and clinical research Nicholas Turner, Batu K. Sharma‐Kuinkel, Stacey A. Maskarinec et al. · Nature Reviews Microbiology ReviewOpen access 8 Feb 2019 2,111
20 Declaración PRISMA 2020: una guía actualizada para la publicación de revisiones sistemáticas Matthew James Page et al. · Revista Española de Cardiología Open access 21 Jul 2021 2,100
21 Management of Hyperglycemia in Type 2 Diabetes, 2022. A Consensus Report by the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD) Melanie J. Davies, Vanita R. Aroda, Billy S. Collins et al. · Diabetes Care Open access 23 Sep 2022 2,099
22 A Phase 3, Randomized, Controlled Trial of Resmetirom in NASH with Liver Fibrosis Stephen A. Harrison et al. · New England Journal of Medicine Open access 7 Feb 2024 1,963
23 Large-Scale Assessment of a Smartwatch to Identify Atrial Fibrillation Marco Valentin Perez et al. · New England Journal of Medicine Open access 13 Nov 2019 1,953
24 Sotagliflozin in Patients with Diabetes and Recent Worsening Heart Failure Deepak L. Bhatt, Michael J. Szarek, Philippe Gabríel Steg et al. · New England Journal of Medicine Open access 16 Nov 2020 1,872
25 Albiglutide and cardiovascular outcomes in patients with type 2 diabetes and cardiovascular disease (Harmony Outcomes): a double-blind, randomised placebo-controlled trial Adrian F. Hernandez et al. · The Lancet Open access808 authors Oct 2018 1,848
26 How Many Focus Groups Are Enough? Building an Evidence Base for Nonprobability Sample Sizes Greg Guest, Emily Namey, Kevin Christopher McKenna · Field Methods 28 Apr 2016 1,802
27 5-year outcomes of transcatheter aortic valve replacement or surgical aortic valve replacement for high surgical risk patients with aortic stenosis (PARTNER 1): a randomised controlled trial Michael J. Mack et al. · The Lancet 15 Mar 2015 1,761
28 Fluoxetine, Cognitive-Behavioral Therapy, and Their Combination for Adolescents With Depression Treatment for Adolescents With Depression Study (TADS) Team · JAMA Open access 17 Aug 2004 1,755
29 Diuretic Strategies in Patients with Acute Decompensated Heart Failure Gary Michael Felker et al. · New England Journal of Medicine Open access 3 Mar 2011 1,724
30 Prediction of risk of death and myocardial infarction in the six months after presentation with acute coronary syndrome: prospective multinational observational study (GRACE) Keith A.A. Fox, Omar H. Dabbous, Robert Joel Goldberg et al. · BMJ Open access 10 Oct 2006 1,704
31 Low Diagnostic Yield of Elective Coronary Angiography Manesh R. Patel, Eric David Peterson, David W. H. Dai et al. · New England Journal of Medicine Open access 10 Mar 2010 1,674
32 Prevention of Bleeding in Patients with Atrial Fibrillation Undergoing PCI Charles Michael Gibson, Roxana Mehran, Christoph Bode et al. · New England Journal of Medicine Open access 14 Nov 2016 1,595
33 Cardiovascular, mortality, and kidney outcomes with GLP-1 receptor agonists in patients with type 2 diabetes: a systematic review and meta-analysis of randomised trials Naveed A. Sattar, Matthew M.Y. Lee, Søren Lund Kristensen et al. · The Lancet Diabetes & Endocrinology ReviewOpen access 20 Aug 2021 1,590
34 The World Federation of ADHD International Consensus Statement: 208 Evidence-based conclusions about the disorder Stephen V. Faraone et al. · Neuroscience & Biobehavioral Reviews Open access 4 Feb 2021 1,541
35 Outcomes of Anatomical versus Functional Testing for Coronary Artery Disease Pamela S. Douglas, Udo Hoffmann, Manesh R. Patel et al. · New England Journal of Medicine Open access 14 Mar 2015 1,539
36 Evaluation Study of Congestive Heart Failure and Pulmonary Artery Catheterization Effectiveness The ESCAPE Investigators and ESCAPE Study Coordinators* · JAMA Open access 4 Oct 2005 1,537
37 Effect of Catheter Ablation vs Antiarrhythmic Drug Therapy on Mortality, Stroke, Bleeding, and Cardiac Arrest Among Patients With Atrial Fibrillation Douglas L. Packer et al. · JAMA Open access 15 Mar 2019 1,517
38 Dabigatran versus Warfarin in Patients with Mechanical Heart Valves John W. Eikelboom, Stuart J. Connolly, Martina Brueckmann et al. · New England Journal of Medicine Sep 2013 1,514
39 Prognostic Importance of Defibrillator Shocks in Patients with Heart Failure Jeanne E. Poole, George William Johnson, Anne S. Hellkamp et al. · New England Journal of Medicine Open access 3 Sep 2008 1,470
40 Inhibition of Platelet Glycoprotein IIb/IIIa with Eptifibatide in Patients with Acute Coronary Syndromes The PURSUIT trial investigators · New England Journal of Medicine Open access 13 Aug 1998 1,444
41 Prevalence of Obesity and Severe Obesity in US Children, 1999–2016 Asheley Cockrell Skinner, Sophie N. Ravanbakht, Joseph A. Skelton et al. · PEDIATRICS Open access 26 Feb 2018 1,439
42 A Comparison of Low-Molecular-Weight Heparin with Unfractionated Heparin for Unstable Coronary Artery Disease Marc J. Cohen, Christine Demers, Enrique Gurfinkel et al. · New England Journal of Medicine Open access 14 Aug 1997 1,433
43 Vericiguat in Patients with Heart Failure and Reduced Ejection Fraction Paul W. Armstrong, Burkert Mathias Pieske, Kevin Joseph Anstrom et al. · New England Journal of Medicine Open access 28 Mar 2020 1,350
44 National Sleep Foundation's sleep quality recommendations: first report Maurice Moyses Ohayon, Emerson M. Wickwire, Max Hirshkowitz et al. · Sleep Health Open access 23 Dec 2016 1,328
45 Medical Therapy for Heart Failure With Reduced Ejection Fraction Stephen John Greene, Javed Butler, Nancy M. Albert et al. · Journal of the American College of Cardiology Open access Jul 2018 1,322
46 Coronary-Artery Bypass Surgery in Patients with Left Ventricular Dysfunction Eric J. Velazquez et al. · New England Journal of Medicine Open access 4 Apr 2011 1,311
47 Radial versus femoral access in patients with acute coronary syndromes undergoing invasive management: a randomised multicentre trial Marco Valgimigli et al. · The Lancet Open access 18 Mar 2015 1,311
48 Effect of Dexamethasone on Days Alive and Ventilator-Free in Patients With Moderate or Severe Acute Respiratory Distress Syndrome and COVID-19 Bruno Martins Tomazini et al. · JAMA Open access 2 Sep 2020 1,309
49 Drotrecogin Alfa (Activated) in Adults with Septic Shock V. Marco Ranieri, Bruce Thompson, Philip S. Barie et al. · New England Journal of Medicine 31 May 2012 1,303
50 Comparison of Angioplasty with Stenting, with or without Abciximab, in Acute Myocardial Infarction Gregg W. Stone, Cindy Lee Grines, David Alan Cox et al. · New England Journal of Medicine Open access 28 Mar 2002 1,282

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.