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Most cited papers from Clinical Science Institute

What are the most cited papers from Clinical Science Institute?

The most cited paper from Clinical Science Institute is "Long-term omeprazole treatment in resistant gastroesophageal reflux disease: Efficacy, safety, and influence on gastric mucosa" (Elly C. Klinkenberg–Knol, Frits G. Nelis, John Dent et al., 2000), with 545 citations. Next come "Role of Plasma Carcinoembryonic Antigen in Diagnosis of Gastrointestinal, Mammary, and Bronchial Carcinoma" (315) and "Impact of electro-acupuncture and physical exercise on hyperandrogenism and oligo/amenorrhea in women with polycystic ovary syndrome: a randomized controlled trial" (227).

Showing 50 of 60 papers. Every paper with more than 59 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 Long-term omeprazole treatment in resistant gastroesophageal reflux disease: Efficacy, safety, and influence on gastric mucosa Elly C. Klinkenberg–Knol, Frits G. Nelis, John Dent et al. · Gastroenterology Open access Apr 2000 545
2 Role of Plasma Carcinoembryonic Antigen in Diagnosis of Gastrointestinal, Mammary, and Bronchial Carcinoma D. J. R. Laurence, U. Stevens, Radka Bettelheim et al. · BMJ Open access 9 Sep 1972 315
3 Impact of electro-acupuncture and physical exercise on hyperandrogenism and oligo/amenorrhea in women with polycystic ovary syndrome: a randomized controlled trial Elizabeth Jedel, Fernand Labrie, Anders Odén et al. · American Journal of Physiology-Endocrinology and Metabolism 14 Oct 2010 227
4 Expression of the Wilms' Tumor Gene WT1 in Solid Tumors and Its Involvement in Tumor Cell Growth Yusuke Oji, Hiroyasu Ogawa, Hiroya Tamaki et al. · Japanese Journal of Cancer Research Open access Feb 1999 211
5 Inhibitory effect of leptin on human uterine contractility in vitro Audrey T. Moynihan, Mark P. Hehir, Siobhan V. Glavey et al. · American Journal of Obstetrics and Gynecology 5 May 2006 183
6 Repair of human articular cartilage after implantation of autologous chondrocytes James Bruce Richardson, Bruce Caterson, E. Helena Evans et al. · Journal of Bone and Joint Surgery - British Volume Nov 1999 160
7 A Haplotype Containing Quantitative Trait Loci for SLC1A1 Gene Expression and Its Association With Obsessive-Compulsive Disorder Jens R. Wendland, Pablo R. Moya, Kiara R. Timpano et al. · Archives of General Psychiatry Open access Apr 2009 149
8 Microvessel count predicts survival in uveal melanoma. Alexander J. E. Foss, Robert Alexander, L W Jefferies et al. · PubMed Jul 1996 144
9 Epidemiology and outcomes of gastroparesis, as documented in general practice records, in the United Kingdom Yizhou Ye, Baoguo Jiang, Sudhakar Manne et al. · Gut Open access 3 Jun 2020 140
10 A novel, putative gain-of-function haplotype at SLC6A4 associates with obsessive-compulsive disorder Jens R. Wendland, Pablo R. Moya, Matthew Kruse et al. · Human Molecular Genetics 16 Nov 2007 139
11 Longterm Safety and Efficacy of Tocilizumab in Patients with Rheumatoid Arthritis: A Cumulative Analysis of Up to 4.6 Years of Exposure Mark C. Genovese, Andrea Rubbert‐Roth, Josef S. Smolen et al. · The Journal of Rheumatology Open access Mar 2013 138
12 Racial differences in the results of glaucoma filtration surgery: are racial differences in the conjunctival cell profile important? David C. Broadway, Ian Grierson, Roger A. Hitchings · British Journal of Ophthalmology Open access Jun 1994 137
13 'Inappropriate' attenders at accident and emergency departments I: definition, incidence and reasons for attendance Andrew William Murphy · Family Practice Open access Feb 1998 132
14 Human target validation of phosphoinositide 3‐kinase (PI3K)β: effects on platelets and insulin sensitivity, using AZD6482 a novel PI3Kβ inhibitor Sven Nylander, Bengt Kull, Jan‐Arne Björkman et al. · Journal of Thrombosis and Haemostasis Open access 20 Aug 2012 129
15 Evaluation of spectral photon counting computed tomography K-edge imaging for determination of gold nanoparticle biodistribution in vivo Salim Aymeric Si-Mohamed, David P. Cormode, Daniel Bar-Ness et al. · Nanoscale Open access 2017 128
16 The diagnosis of delayed post-operative endophthalmitis by polymerase chain reaction of bacterial DNA in vitreous samples Philip G. Hykin, Khalid Tobal, G. McIntyre et al. · Journal of Medical Microbiology Jun 1994 123
17 Risk Stratification for Distal Pancreatectomy Utilizing ACS-NSQIP: Preoperative Factors Predict Morbidity and Mortality Kaitlyn Jane Kelly, David Yü Greenblatt, Yin Wan et al. · Journal of Gastrointestinal Surgery 15 Dec 2010 116
18 Cleaning at Home and at Work in Relation to Lung Function Decline and Airway Obstruction Øistein Svanes et al. · American Journal of Respiratory and Critical Care Medicine 16 Feb 2018 110
19 Celiac Sprue and Immunodeficiency States: A 25-Year Review Michael A. Heneghan, Fiona M. Stevens, Eilis M. Cryan' et al. · Journal of Clinical Gastroenterology Sep 1997 108
20 Regulation and function of mitophagy in development and cancer Haiqi Lu, Guangliang Li, Leiming Liu et al. · Autophagy Open access 3 Nov 2013 108
21 Sessile Serrated Adenoma With Early Neoplastic Progression Kohei Fujita, Hidetaka Yamamoto, Takayuki Matsumoto et al. · The American Journal of Surgical Pathology Open access 22 Jan 2011 107
22 Relationship of Blood Group Determinants on Helicobacter pylori Lipopolysaccharide with Host Lewis Phenotype and Inflammatory Response Michael A. Heneghan, Ciaran F. McCarthy, Anthony P. Moran · Infection and Immunity Open access Feb 2000 105
23 Young Patient Trabeculectomy Jörg Peter Egon Stürmer, David C. Broadway, Roger A. Hitchings · Ophthalmology Jun 1993 104
24 Hereditary tyrosinemia type I. Self-induced correction of the fumarylacetoacetase defect. E. A. Kvittingen, Helge Rootwelt, Petter Brandtzaeg et al. · Journal of Clinical Investigation Open access Apr 1993 103
25 Comparison of the C-MAC®, Airtraq®, and Macintosh laryngoscopes in patients undergoing tracheal intubation with cervical spine immobilization Jennifer C. McElwain, John Gerard Laffey · British Journal of Anaesthesia Open access 17 May 2011 102
26 FEBRILE NEUTROPENIA IN ACUTE LEUKEMIA. EPIDEMIOLOGY, ETIOLOGY, PATHOPHYSIOLOGY AND TREATMENT Bent‐Are Hansen, Øystein Wendelbo, Øyvind Bruserud et al. · Mediterranean Journal of Hematology and Infectious Diseases Open access 30 Dec 2019 100
27 Cancer risk among gingivitis and periodontitis patients: a nationwide cohort study Bo Wen, Stella Chin‐Shaw Tsai, Cheng‐Li Lin et al. · QJM Open access 11 Dec 2013 100
28 Hypercapnia and Acidosis in Sepsis Gerard F. Curley, Maya Contreras, Alistair D. Nichol et al. · Anesthesiology Open access 16 Jan 2010 99
29 Increasing prevalence of overweight in young schoolchildren in Umeå, Sweden, from 1986 to 2001 Solveig Petersen, C Brulin, E Bergström · Acta Paediatrica Jul 2003 99
30 The 5-Year Incidence and Risk Factors for Age-Related Maculopathy in a General Japanese Population: The Hisayama Study Miho Miyazaki, Yutaka Kiyohara, Ayako Yoshida et al. · Investigative Ophthalmology & Visual Science 24 May 2005 97
31 Rat Fighting Behavior: Serum Dopamine-β-Hydroxylase and Hypothalamic Tyrosine Hydroxylase Friedhelm Lamprecht, Burr S. Eichelman, Nguyen B. Thoa et al. · Science 29 Sep 1972 92
32 Temporal movement control in patients with Parkinson's disease. Normand Teasdale, James G. Phillips, George E. Stelmach · Journal of Neurology Neurosurgery & Psychiatry Open access Oct 1990 90
33 Short- and longer-term cancer risks with biologic and targeted synthetic disease-modifying antirheumatic drugs as used against rheumatoid arthritis in clinical practice Viking Huss, Hannah Bower, Hjalmar Wadström et al. · Lara D. Veeken Open access 28 Jul 2021 89
34 Proliferative Vitreoretinopathy David G. Charteris, Paul Stephenson Hiscott, Ian Grierson et al. · Ophthalmology Sep 1992 89
35 Genetic landscape of sporadic vestibular schwannoma Aril Løge Håvik, Ove Bruland, Erling Myrseth et al. · Journal of neurosurgery 14 Apr 2017 84
36 Discussion Margaret M. Altemus, Laura S. Redwine, Yung-Mei Leong et al. · Neuropsychopharmacology Aug 1997 84
37 Perception, Attitudes, Preparedness and Experience of Chemotherapy-Induced Alopecia among Breast Cancer Patients: a Qualitative Study Nayeon Kim, Juhee Cho, Eun‐Kyung Choi et al. · Asian Pacific Journal of Cancer Prevention Open access 30 Apr 2012 83
38 Helicobacter bilis infection in biliary tract cancer Hiroaki Murata, Shingo Tsuji, Masahiko Tsujii et al. · Alimentary Pharmacology & Therapeutics Open access Jul 2004 82
39 Simultaneous application of basic fibroblast growth factor and hepatocyte growth factor to enhance the blood vessels formation Akira Marui, Akihiro Kanematsu, Kenichi Yamahara et al. · Journal of Vascular Surgery Open access 2005 81
40 Randomized Controlled Trial of Febuxostat Versus Allopurinol or Placebo in Individuals with Higher Urinary Uric Acid Excretion and Calcium Stones David S. Goldfarb, PATRICIA A. MacDONALD, Lhanoo Gunawardhana et al. · Clinical Journal of the American Society of Nephrology Open access 9 Aug 2013 78
41 VEGF-A/VEGFR-2 Signaling Leading to cAMP Response Element-Binding Protein Phosphorylation Is a Shared Pathway Underlying the Protective Effect of Preconditioning on Neurons and Endothelial Cells Hsueh‐Te Lee, Ying-Chao Chang, Yi‐Fang Tu et al. · Journal of Neuroscience Open access 8 Apr 2009 76
42 YY1-MIR372-SQSTM1 regulatory axis in autophagy Lifeng Feng, Yanning Ma, Jie Sun et al. · Autophagy Open access 11 Jun 2014 75
43 Deficits in verbal fluency in presymptomatic C9orf72 mutation gene carriers—a developmental disorder Dorothée E. Lulé, Hans‐Peter Müller, Julia Finsel et al. · Journal of Neurology Neurosurgery & Psychiatry Open access 27 Aug 2020 73
44 CD4+Lymphocyte Involvement in Ocular Behclet's Disease D G Charteris, Keith Barton, A C McCartney et al. · Autoimmunity 1992 72
45 Vitamin A absorption in ascariasis Dilip Mahalanabis, KN Jalan, T K Maitra et al. · American Journal of Clinical Nutrition Dec 1976 72
46 Radioimmunoassay of Triiodothyronine in Unextracted Human Serum R. D. Hesch, David Evered · BMJ Open access 17 Mar 1973 71
47 Association Study of 71 European Crohnʼs Disease Susceptibility Loci in a Japanese Population Atsushi Hirano, Keiko Yamazaki, Junji Umeno et al. · Inflammatory Bowel Diseases 7 Feb 2013 68
48 Behcet's disease: activated T lymphocytes in retinal perivasculitis. D G Charteris, C Champ, A. Ralph Rosenthal et al. · British Journal of Ophthalmology Open access Aug 1992 68
49 Reassessment of the PAS patterns in uveal melanoma V. RUMMELT, Gottfried O. H. Naumann, Alexander J. E. Foss et al. · British Journal of Ophthalmology Open access 1998 67
50 Clinical Decision Support and Individualized Prediction of Survival in Colon Cancer: Bayesian Belief Network Model Alexander Stojadinovic, Anton J. Bilchik, David D. Smith et al. · Annals of Surgical Oncology 16 Aug 2012 66

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.