Institution · de Duve Institute
Most cited papers from de Duve Institute
What are the most cited papers from de Duve Institute?
The most cited paper from de Duve Institute is "A unique clonal JAK2 mutation leading to constitutive signalling causes polycythaemia vera" (Chloé James, Valérie Ugo, Jean‐Pierre Le Couedic et al., 2005), with 3,573 citations. Next come "A Gene Encoding an Antigen Recognized by Cytolytic T Lymphocytes on a Human Melanoma" (3,560) and "Evidence for a tumoral immune resistance mechanism based on tryptophan degradation by indoleamine 2,3-dioxygenase" (2,325).
Showing 50 of 60 papers. Every paper with more than 402 citations is listed.
| # | Paper | ||
|---|---|---|---|
| 1 | A unique clonal JAK2 mutation leading to constitutive signalling causes polycythaemia vera Chloé James, Valérie Ugo, Jean‐Pierre Le Couedic et al. · Nature | 27 Mar 2005 | 3,573 |
| 2 | A Gene Encoding an Antigen Recognized by Cytolytic T Lymphocytes on a Human Melanoma Pierre van der Bruggen, Catia Traversari, Patrick Chomez et al. · Science | 13 Dec 1991 | 3,560 |
| 3 | Evidence for a tumoral immune resistance mechanism based on tryptophan degradation by indoleamine 2,3-dioxygenase Catherine Uyttenhove, Luc Pilotte, Ivan Théate et al. · Nature Medicine | 21 Sep 2003 | 2,325 |
| 4 | The Genome of the African Trypanosome Trypanosoma brucei Matthew Berriman et al. · Science | 14 Jul 2005 | 1,699 |
| 5 | Role of PFKFB3-Driven Glycolysis in Vessel Sprouting Katrien De Bock et al. · Cell | Aug 2013 | 1,617 |
| 6 | Vascular Anomalies Classification: Recommendations From the International Society for the Study of Vascular Anomalies Michel Wassef, Francine Blei, Denise M. Adams et al. · PEDIATRICS | 10 Jun 2015 | 1,425 |
| 7 | Transforming growth factor-β 'reprograms' the differentiation of T helper 2 cells and promotes an interleukin 9–producing subset Marc Veldhoen, Catherine Uyttenhove, Jacques Van Snick et al. · Nature Immunology | 19 Oct 2008 | 1,196 |
| 8 | A p16 INK4a -Insensitive CDK4 Mutant Targeted by Cytolytic T Lymphocytes in a Human Melanoma Thomas Wölfel, Martina Hauer, Jörg Schneider et al. · Science | Sep 1995 | 1,158 |
| 9 | Tumour antigens recognized by T lymphocytes: at the core of cancer immunotherapy Pierre G. Coulie, Benoı̂t J. Van den Eynde, Pierre van der Bruggen et al. · Nature reviews. Cancer | 24 Jan 2014 | 1,152 |
| 10 | Oxidative stress, protein damage and repair in bacteria Benjamin Ezraty, Alexandra Gennaris, Frédéric Barras et al. · Nature Reviews Microbiology | 18 Apr 2017 | 1,048 |
| 11 | Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition) Andrea Cossarizza et al. · European Journal of Immunology | Oct 2019 | 1,014 |
| 12 | Rehabilitation of Motor Function after Stroke: A Multiple Systematic Review Focused on Techniques to Stimulate Upper Extremity Recovery Samar M. Hatem, Geoffroy Saussez, Margaux della Faille et al. · Frontiers in Human Neuroscience | 12 Sep 2016 | 945 |
| 13 | Chromosome instability is common in human cleavage-stage embryos Evelyne Vanneste, Thierry Voet, Cédric Le Caignec et al. · Nature Medicine | 26 Apr 2009 | 909 |
| 14 | Interleukin‐6 in synovial fluid and serum of patients with rheumatoid arthritis and other inflammatory arthritides Frédéric Houssiau, Jean‐Pierre Devogelaer, Jo Van Damme et al. · Arthritis & Rheumatism | Jun 1988 | 858 |
| 15 | Interleukin 27 limits autoimmune encephalomyelitis by suppressing the development of interleukin 17–producing T cells Marcel Batten, Ji Li, Sothy Yi et al. · Nature Immunology | 13 Aug 2006 | 834 |
| 16 | Phosphorylation and activation of heart PFK-2 by AMPK has a role in the stimulation of glycolysis during ischaemia A-S. Marsin, Luc Bertrand, Mark H. Rider et al. · Current Biology | Oct 2000 | 832 |
| 17 | Organogenesis and Development of the Liver Karim Si‐Tayeb, Frédéric P. Lemaigre, Stephen A. Duncan · Developmental Cell | Feb 2010 | 800 |
| 18 | The Virulence Plasmid ofYersinia, an Antihost Genome Guy R. Cornelis, Anne Boland, Aoife Boyd et al. · Microbiology and Molecular Biology Reviews | Dec 1998 | 792 |
| 19 | Assembly and Function of Type III Secretory Systems Guy R. Cornelis, Frédérique Van Gijsegem · Annual Review of Microbiology | Oct 2000 | 782 |
| 20 | IFN-Lambda (IFN-λ) Is Expressed in a Tissue-Dependent Fashion and Primarily Acts on Epithelial Cells In Vivo Caroline Sommereyns, Sophie Paul, Peter Staeheli et al. · PLoS Pathogens | 13 Mar 2008 | 777 |
| 21 | Vitamin C Carole L. Linster, Emile Van Schaftingen · FEBS Journal | 6 Dec 2006 | 762 |
| 22 | Capillary Malformation–Arteriovenous Malformation, a New Clinical and Genetic Disorder Caused by RASA1 Mutations Iiro Eerola, Laurence Myriam Boon, John Butler Mulliken et al. · The American Journal of Human Genetics | Dec 2003 | 760 |
| 23 | The Randle cycle revisited: a new head for an old hat Louis Hue, Heinrich Taegtmeyer · American Journal of Physiology-Endocrinology and Metabolism | 16 Jun 2009 | 756 |
| 24 | Tryptophan Catabolism in Cancer: Beyond IDO and Tryptophan Depletion Michael Platten, Wolfgang Wick, Benoı̂t J. Van den Eynde · Cancer Research | 23 Oct 2012 | 713 |
| 25 | A Kinetic Study of Pyrophosphate: Fructose‐6‐Phosphate Phosphotransferase from Potato Tubers Emile Van Schaftingen, B Lederer, Ramón Bartrons et al. · European Journal of Biochemistry | Dec 1982 | 660 |
| 26 | DNA Methylation Is the Primary Silencing Mechanism for a Set of Germ Line- and Tumor-Specific Genes with a CpG-Rich Promoter Charles De Smet, Christophe Lurquin, Bernard Lethé et al. · Molecular and Cellular Biology | Nov 1999 | 601 |
| 27 | Reversal of tumoral immune resistance by inhibition of tryptophan 2,3-dioxygenase Luc Pilotte, Pierre Larrieu, Vincent Stroobant et al. · Proceedings of the National Academy of Sciences | 30 Jan 2012 | 579 |
| 28 | Innate lymphoid cells regulate intestinal epithelial cell glycosylation Yoshiyuki Goto et al. · Science | 21 Aug 2014 | 576 |
| 29 | Somatic mosaic IDH1 and IDH2 mutations are associated with enchondroma and spindle cell hemangioma in Ollier disease and Maffucci syndrome Twinkal C. Pansuriya et al. · Nature Genetics | 6 Nov 2011 | 571 |
| 30 | The Yersinia Yop virulon: a bacterial system for subverting eukaryotic cells Guy R. Cornelis, Hans Wolf‐Watz · Molecular Microbiology | Mar 1997 | 561 |
| 31 | JAK/STAT signaling in hematological malignancies William Vainchenker, Stefan N. Constantinescu · Oncogene | 6 Aug 2012 | 546 |
| 32 | NetPath: a public resource of curated signal transduction pathways Kumaran Kandasamy et al. · Genome biology | 12 Jan 2010 | 541 |
| 33 | Tumor antigens recognized by T cells Thierry Boon, Pierre G. Coulie, Benoı̂t Van den Eynde · Immunology Today | Jun 1997 | 541 |
| 34 | Translocation of a hybrid YopE‐adenylate cyclase from Yersinia enterocolitica into HeLa cells M.‐P. Sory, Guy R. Cornelis · Molecular Microbiology | Nov 1994 | 535 |
| 35 | Activation of AMP‐activated protein kinase in the liver: a new strategy for the management of metabolic hepatic disorders Benoı̂t Viollet, Marc Foretz, Bruno Guigas et al. · The Journal of Physiology | 28 Apr 2006 | 532 |
| 36 | DMP1 mutations in autosomal recessive hypophosphatemia implicate a bone matrix protein in the regulation of phosphate homeostasis Bettina Lorenz‐Depiereux, Murat Bastepe, Anna Benet‐Pagès et al. · Nature Genetics | 8 Oct 2006 | 529 |
| 37 | Long-term findings from COMFORT-II, a phase 3 study of ruxolitinib vs best available therapy for myelofibrosis on behalf of the COMFORT-II Investigators, Claire N. Harrison, Alessandro Maria Vannucchi et al. · Leukemia | 23 May 2016 | 521 |
| 38 | Mechanisms of glucocorticoid-induced myopathy O Schakman, Hélène Gilson, Jean‐Paul Thissen · Journal of Endocrinology | 31 Jan 2008 | 511 |
| 39 | Somatic mutations in angiopoietin receptor gene TEK cause solitary and multiple sporadic venous malformations Nisha Limaye, Vinciane Wouters, Mélanie Uebelhoer et al. · Nature Genetics | 14 Dec 2008 | 504 |
| 40 | Cloning and Characterization of IL-10-Related T Cell-Derived Inducible Factor (IL-TIF), a Novel Cytokine Structurally Related to IL-10 and Inducible by IL-9 Laure Dumoutier, Jamila Louahed, Jean‐Christophe Renauld · The Journal of Immunology | Feb 2000 | 503 |
| 41 | AMP‐activated protein kinase in the regulation of hepatic energy metabolism: from physiology to therapeutic perspectives Benoı̂t Viollet, Bruno Guigas, J Leclerc et al. · Acta Physiologica | 19 Feb 2009 | 489 |
| 42 | Classification of current anticancer immunotherapies Lorenzo Galluzzi et al. · Oncotarget | 18 Dec 2014 | 475 |
| 43 | Identification of the YopE and YopH domains required for secretion and internalization into the cytosol of macrophages, using the cyaA gene fusion approach. Marie‐Paule Sory, Anne Boland, Isabelle Lambermont et al. · Proceedings of the National Academy of Sciences | 19 Dec 1995 | 473 |
| 44 | Activation of AMP-Activated Protein Kinase Leads to the Phosphorylation of Elongation Factor 2 and an Inhibition of Protein Synthesis Sandrine Horman, Gareth J. Browne, U. Krause et al. · Current Biology | Aug 2002 | 456 |
| 45 | 6-Phosphofructo-2-kinase/fructose-2,6-bisphosphatase: head-to-head with a bifunctional enzyme that controls glycolysis Mark H. Rider, Luc Bertrand, Didier Vertommen et al. · Biochemical Journal | 27 Jul 2004 | 452 |
| 46 | Notch signaling controls liver development by regulating biliary differentiation Yiwei Zong, Archana Panikkar, Jie Xu et al. · Development | 15 Apr 2009 | 451 |
| 47 | Lambda Interferon Renders Epithelial Cells of the Respiratory and Gastrointestinal Tracts Resistant to Viral Infections Markus Mordstein, Eva Neugebauer, Vanessa Ditt et al. · Journal of Virology | 24 Mar 2010 | 447 |
| 48 | The determinants of tumour immunogenicity Thomas J. F. Blankenstein, Pierre G. Coulie, Eli Gilboa et al. · Nature reviews. Cancer | Mar 2012 | 442 |
| 49 | Parkes Weber syndrome, vein of Galen aneurysmal malformation, and other fast-flow vascular anomalies are caused byRASA1 mutations Nicole Revençu et al. · Human Mutation | 2008 | 437 |
| 50 | Congenital Hereditary Lymphedema Caused by a Mutation That Inactivates VEGFR3 Tyrosine Kinase Alexandre Irrthum, Marika J. Karkkainen, Koenraad Devriendt et al. · The American Journal of Human Genetics | Aug 2000 | 437 |
Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.