| 1 |
A Phase 2 Study of Chronocort, a Modified-Release Formulation of Hydrocortisone, in the Treatment of Adults With Classic Congenital Adrenal Hyperplasia
Ashwini Mallappa, Ninet Sinaii, Parag Kumar et al. · The Journal of Clinical Endocrinology & Metabolism
Open access |
11 Dec 2014 |
165 |
| 2 |
Salivary Cortisone Reflects Cortisol Exposure Under Physiological Conditions and After Hydrocortisone
Miguel Debono, Robert F. Harrison, Martin J. Whitaker et al. · The Journal of Clinical Endocrinology & Metabolism
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26 Jan 2016 |
127 |
| 3 |
An oral multiparticulate, modified‐release, hydrocortisone replacement therapy that provides physiological cortisol exposure
Martin J. Whitaker, Miguel Debono, Hiep Huatan et al. · Clinical Endocrinology
Open access |
27 Aug 2013 |
121 |
| 4 |
Modified-Release Hydrocortisone in Congenital Adrenal Hyperplasia
Deborah P. Merke, Ashwini Mallappa, Wiebke Arlt et al. · The Journal of Clinical Endocrinology & Metabolism
Open access |
29 Jan 2021 |
87 |
| 5 |
Poor compliance and increased mortality, depression and healthcare costs in patients with congenital adrenal hyperplasia
Sara Jenkins‐Jones, Lotta Parviainen, John B. Porter et al. · European Journal of Endocrinology
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26 Jan 2018 |
85 |
| 6 |
Absorption and tolerability of taste‐masked hydrocortisone granules in neonates, infants and children under 6 years of age with adrenal insufficiency
Uta Neumann, Martin J. Whitaker, Susanna Wiegand et al. · Clinical Endocrinology
Open access |
17 Aug 2017 |
63 |
| 7 |
Modified release and conventional glucocorticoids and diurnal androgen excretion in congenital adrenal hyperplasia
Christopher Mark Jones, Ashwini Mallappa, Nicole Reisch et al. · The Journal of Clinical Endocrinology & Metabolism
Open access |
15 Nov 2016 |
60 |
| 8 |
Is physiological glucocorticoid replacement important in children?
John B. Porter, Joanne Blair, Richard John M Ross · Archives of Disease in Childhood
Open access |
31 Aug 2016 |
50 |
| 9 |
Development and Testing in Healthy Adults of Oral Hydrocortisone Granules With Taste Masking for the Treatment of Neonates and Infants With Adrenal Insufficiency
Martin J. Whitaker, Sarah Spielmann, Dena Digweed et al. · The Journal of Clinical Endocrinology & Metabolism
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3 Feb 2015 |
48 |
| 10 |
8th European Conference on Rare Diseases & Orphan Products (ECRD 2016)
Michael Schlander et al. · Orphanet Journal of Rare Diseases
Open access |
Nov 2016 |
40 |
| 11 |
A Prospective Study of Children Aged 0–8 Years with CAH and Adrenal Insufficiency Treated with Hydrocortisone Granules
Uta Neumann, Katarina Braune, Martin J. Whitaker et al. · The Journal of Clinical Endocrinology & Metabolism
Open access |
4 Sep 2020 |
37 |
| 12 |
General and Cancer Mortality in a Large Cohort of Italian Alcoholics
Calogero Saieva, Gabriele Bardazzi, Giovanna Masala et al. · Alcoholism Clinical and Experimental Research
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15 Nov 2011 |
31 |
| 13 |
A Biopredictive In Vitro Approach for Assessing Compatibility of a Novel Pediatric Hydrocortisone Drug Product within Common Pediatric Dosing Vehicles
Erik Wollmer, Frank Karkossa, Lisa Freerks et al. · Pharmaceutical Research
Open access |
24 Sep 2020 |
30 |
| 14 |
Immediate-release granule formulation of hydrocortisone, Alkindi®, for treatment of paediatric adrenal insufficiency (Infacort development programme)
John B. Porter, Mike Withe, Richard John M Ross · Expert Review of Endocrinology & Metabolism
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21 Mar 2018 |
26 |
| 15 |
Biorelevant in vitro assessment of dissolution and compatibility properties of a novel paediatric hydrocortisone drug product following exposure of the drug product to child-appropriate administration fluids
Erik Wollmer, Greg Neal, Martin J. Whitaker et al. · European Journal of Pharmaceutics and Biopharmaceutics
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29 Oct 2018 |
23 |
| 16 |
Development and verification of an endogenous PBPK model to inform hydrocortisone replacement dosing in children and adults with cortisol deficiency
Jennifer J. Bonner, Howard J. Burt, Trevor N. Johnson et al. · European Journal of Pharmaceutical Sciences
Open access |
17 Jun 2021 |
21 |
| 17 |
Predicting Cortisol Exposure from Paediatric Hydrocortisone Formulation Using a Semi-Mechanistic Pharmacokinetic Model Established in Healthy Adults
Johanna Melin, Zinnia Patricia Parra-Guillen, Niklas Hartung et al. · Clinical Pharmacokinetics
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31 Jul 2017 |
17 |
| 18 |
Glucocorticoids regulate AKR1D1 activity in human liver in vitro and in vivo
Nikolaos Nikolaou, Anastasia Arvaniti, Nathan Appanna et al. · Journal of Endocrinology
Open access |
27 Feb 2020 |
16 |
| 19 |
Modified-release hydrocortisone is associated with lower plasma renin activity in patients with salt-wasting congenital adrenal hyperplasia
Lea Tschaidse, Nicole Reisch, Wiebke Arlt et al. · European Journal of Endocrinology
Open access |
2023 |
15 |
| 20 |
Chronotherapy based on modified-release hydrocortisone to restore the physiological cortisol diurnal rhythm
Martin J. Whitaker, Hiep Huatan, Richard John M Ross · Drug Delivery and Translational Research
Open access |
26 May 2022 |
15 |
| 21 |
The circadian rhythm of corticosteroid‐binding globulin has little impact on cortisol exposure after hydrocortisone dosing
Johanna Melin, Niklas Hartung, Zinnia Patricia Parra-Guillen et al. · Clinical Endocrinology
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14 Mar 2019 |
15 |
| 22 |
Adrenal Insufficiency in Young Children: a Mixed Methods Study of Parents’ Experiences
Amy Simpson, Richard John M Ross, John B. Porter et al. · Journal of Genetic Counseling
Open access |
7 Jul 2018 |
14 |
| 23 |
Hydrocortisone Granules Are Bioequivalent When Sprinkled Onto Food or Given Directly on the Tongue
Eleni Daniel, Dena Digweed, J. F. Quirke et al. · Journal of the Endocrine Society
Open access |
27 Feb 2019 |
10 |
| 24 |
Paediatric population pharmacokinetic modelling to assess hydrocortisone replacement dosing regimens in young children
Robin Michelet, Johanna Melin, Zinnia Patricia Parra-Guillen et al. · European Journal of Endocrinology
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3 Jul 2020 |
9 |
| 25 |
Hydrocortisone granules in capsules for opening (Alkindi) as replacement therapy in pediatric patients with adrenal insufficiency
Helen Coope, Lotta Parviainen, Mike Withe et al. · Expert Opinion on Orphan Drugs
Open access |
4 Mar 2021 |
8 |
| 26 |
Exploring Dried Blood Spot Cortisol Concentrations as an Alternative for Monitoring Pediatric Adrenal Insufficiency Patients: A Model-Based Analysis
Viktoria Stachanow, Uta Neumann, Oliver Blankenstein et al. · Frontiers in Pharmacology
Open access |
17 Mar 2022 |
7 |
| 27 |
An oral lipidic native testosterone formulation that is absorbed independent of food
John D C Newell-Price, Hiep Huatan, J. F. Quirke et al. · European Journal of Endocrinology
Open access |
11 Aug 2021 |
6 |
| 28 |
Insights in the maturational processes influencing hydrocortisone pharmacokinetics in congenital adrenal hyperplasia patients using a middle-out approach
Robin Michelet, Davide Bindellini, Johanna Melin et al. · Frontiers in Pharmacology
Open access |
12 Jan 2023 |
5 |
| 29 |
Impact of food, alcohol and pH on modified-release hydrocortisone developed to treat congenital adrenal hyperplasia
Nayananjani Karunasena, Daniel N. Margetson, Greg Neal et al. · European Journal of Endocrinology
Open access |
19 Jan 2017 |
5 |
| 30 |
OR25-02 A Phase 3 Study of a Modified-Release Hydrocortisone in the Treatment of Congenital Adrenal Hyperplasia
Deborah P. Merke, Ashwini Mallappa, Wiebke Arlt et al. · Journal of the Endocrine Society
Open access |
Apr 2020 |
4 |
| 31 |
Patient and Caregiver Burden in Congenital Adrenal Hyperplasia (CAH) in Children: Results of a Structured Literature Review
Lotta Parviainen, John B. Porter, Mike Withe et al. · Value in Health
Open access |
Oct 2017 |
2 |
| 32 |
9341 CHAMPAIN Study: Initial Results From A Phase II Study Of Efficacy, Safety And Tolerability Of Modified-release Hydrocortisones: Chronocort® (Efmody®) Versus Plenadren®, In Primary Adrenal Insufficiency
Alessandro Prete, Verena Theiler‐Schwetz, Wiebke Arlt et al. · Journal of the Endocrine Society
Open access |
Oct 2024 |
1 |
| 33 |
12670 CHAMPAIN Study: Initial Results From A Phase II Study Of Efficacy, Safety And Tolerability Of Modified-release Hydrocortisones: Chronocort® (Efmody®) Versus Plenadren®, In Primary Adrenal Insufficiency
Alessandro Prete, Verena Theiler‐Schwetz, Wiebke Arlt et al. · Journal of the Endocrine Society
Open access |
Oct 2024 |
1 |
| 34 |
SAT304 Improved Biochemical Control With Dose Reduction In Chronic Glucocorticoid Therapy: A Phase III Extension Study Of Chronocort (Efmody) In The Treatment Of Congenital Adrenal Hyperplasia (CAH)
Richard John M Ross, Deborah P. Merke, Ashwini Mallappa et al. · Journal of the Endocrine Society
Open access |
Oct 2023 |
1 |
| 35 |
The Burden of Illness of Congenital Adrenal Hyperplasia (CAH) in Adults: Results: of a Structured Literature Review
Matthew Woods, Helen Coope, Kamran Maskin et al. · Journal of the Endocrine Society
Open access |
May 2021 |
1 |
| 36 |
Response to ‘Hydrocortisone suspension formulations are not necessarily the same in the treatment of children with congenital adrenal hyperplasia’
Robin Michelet, Johanna Melin, Zinnia Patricia Parra-Guillen et al. · European Journal of Endocrinology
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28 Sep 2020 |
1 |
| 37 |
7061 Incidence of Adrenal Crisis In Congenital Adrenal Hyperplasia (CAH) Patients During A Prospective Monitored Long-Term Study Of Modified-Release Hydrocortisone (MRHC) Capsules, (Efmody)
Richard John M Ross, Deborah P. Merke, Ashwini Mallappa et al. · Journal of the Endocrine Society
Open access |
Oct 2024 |
0 |
| 38 |
7692 Morning Cortisol Levels In Patients With Established Primary Adrenal Insufficiency
Alessandro Prete, Verena Theiler‐Schwetz, Wiebke Arlt et al. · Journal of the Endocrine Society
Open access |
Oct 2024 |
0 |
| 39 |
O imaginário da morte repousante em Hilda Hilst
Enivalda Nunes Freitas e Souza · Revista Texto Poético
Open access |
26 May 2014 |
0 |
| 40 |
SAT-LB6 First Human Trial of an Oral Native Testosterone Shows Physiological Levels of Testosterone and Dht in Both Fasted and Fed State in Hypogonadal Men
John D C Newell-Price, John B. Porter, J. F. Quirke et al. · Journal of the Endocrine Society
Open access |
Apr 2020 |
0 |
| 41 |
Biorelevant dissolution and compatibility of hydrocortisone granules following exposure to water, breast-, whole- and artificial (formula) milk
Erik Wollmer, Greg Neal, Martin J. Whitaker et al. · International Journal of Pharmaceutics
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Feb 2018 |
0 |