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Most cited papers from Dogo Onsen Hospital

What are the most cited papers from Dogo Onsen Hospital?

The most cited paper from Dogo Onsen Hospital is "Meta-analysis identifies nine new loci associated with rheumatoid arthritis in the Japanese population" (Yukinori Okada et al., 2012), with 336 citations. Next come "Successful use of a humanized anti–interleukin‐6 receptor antibody, tocilizumab, to treat amyloid A amyloidosis complicating juvenile idiopathic arthritis" (150) and "Drug free REmission/low disease activity after cessation of tocilizumab (Actemra) Monotherapy (DREAM) study" (120).

Showing 50 of 57 papers. Every paper with more than 4 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 Meta-analysis identifies nine new loci associated with rheumatoid arthritis in the Japanese population Yukinori Okada et al. · Nature Genetics 25 Mar 2012 336
2 Successful use of a humanized anti–interleukin‐6 receptor antibody, tocilizumab, to treat amyloid A amyloidosis complicating juvenile idiopathic arthritis Yasuaki Okuda, Kiyoshi Takasugi · Arthritis & Rheumatism 31 Aug 2006 150
3 Drug free REmission/low disease activity after cessation of tocilizumab (Actemra) Monotherapy (DREAM) study Norihiro Nishimoto et al. · Modern Rheumatology 22 Nov 2013 120
4 SECONDARY AMYLOIDOSIS IN PATIENTS WITH RHEUMATOID ARTHRITIS: DIAGNOSTIC AND PROGNOSTIC VALUE OF GASTRODUODENAL BIOPSY Hiroaki Kobayashi, Shuji Tada, Takeshi Fuchigami et al. · Lara D. Veeken 1996 112
5 β2-Glycoprotein I/HLA class II complexes are novel autoantigens in antiphospholipid syndrome Kenji Tanimura, Hui Jin, Tadahiro Suenaga et al. · Blood Open access 3 Mar 2015 76
6 Autoantibodies to IgG/HLA class II complexes are associated with rheumatoid arthritis susceptibility Hui Jin et al. · Proceedings of the National Academy of Sciences Open access 24 Feb 2014 73
7 Comparison of the clinical utility of tocilizumab and anti-TNF therapy in AA amyloidosis complicating rheumatic diseases Yasuaki Okuda, Makoto Ohnishi, Kenichiro Matoba et al. · Modern Rheumatology 22 Nov 2013 72
8 Review of tocilizumab in the treatment of rheumatoid arthritis Yasuaki Okuda · Biologics Open access Mar 2008 65
9 Successful tocilizumab treatment in a patient with adult-onset Still’s disease complicated by chronic active hepatitis B and amyloid A amyloidosis Dai Kishida, Yasuaki Okuda, Makoto Onishi et al. · Modern Rheumatology 7 Oct 2010 64
10 An allele of serum amyloid A1 associated with amyloidosis in both Japanese and Caucasians Toshiyuki Yamada, Yasuaki Okuda, Kiyoshi Takasugi et al. · Amyloid 2003 62
11 AA amyloidosis – Benefits and prospects of IL-6 inhibitors Yasuaki Okuda · Modern Rheumatology Open access 22 Aug 2018 57
12 A large-scale association study identified multiple HLA-DRB1 alleles associated with ACPA-negative rheumatoid arthritis in Japanese subjects Chikashi C. Terao, Koichiro Ohmura, Yuta Kochi et al. · Annals of the Rheumatic Diseases Open access 28 Aug 2011 57
13 Detection of Interstitial Pneumonitis in Patients with Rheumatoid Arthritis by Measuring Circulating Levels of KL-6, a Human MUC1 Mucin Tetsu Oyama, Nobuoki Kohno, Akihito Yokoyama et al. · Lung Nov 1997 56
14 PTEN gene transfer suppresses the invasive potential of human malignant gliomas by regulating cell invasion-related molecules Koji Furukawa, Yoshiaki Kumon, Hironobu Harada et al. · International Journal of Oncology Open access Jul 2006 41
15 Intractable diarrhoea associated with secondary amyloidosis in rheumatoid arthritis Yasuyuki Okuda, Kiyoshi Takasugi, Tetsu Oyama et al. · Annals of the Rheumatic Diseases Open access Sep 1997 40
16 Anti–interleukin‐6 receptor antibody therapy favors adrenal androgen secretion in patients with rheumatoid arthritis: A randomized, double‐blind, placebo‐controlled study Rainer Hans Straub, Peter Härle, Seizo Yamana et al. · Arthritis & Rheumatism Open access 25 May 2006 37
17 ACPA-Negative RA Consists of Two Genetically Distinct Subsets Based on RF Positivity in Japanese Chikashi C. Terao et al. · PLoS ONE Open access 6 Jul 2012 36
18 The prevalence of endoscopic gastric mucosal damage in patients with rheumatoid arthritis Saki Tsujimoto, Sho Mokuda, Kenichiro Matoba et al. · PLoS ONE Open access 9 Jul 2018 31
19 Sustainable Efficacy of Switching From Intravenous to Subcutaneous Tocilizumab Monotherapy in Patients With Rheumatoid Arthritis Atsushi Ogata et al. · Arthritis Care & Research Open access Apr 2015 31
20 Non-autoimmune combined factor XIII A and B subunit deficiencies in rheumatoid arthritis patients treated with anti-interleukin-6 receptor monoclonal antibody (tocilizumab) Masayoshi Souri, Sho Mokuda, Hiroshi Inanami et al. · Thrombosis Research 27 Feb 2016 29
21 Tocilizumab Induced Acquired Factor XIII Deficiency in Patients with Rheumatoid Arthritis Sho Mokuda, Yosuke Murata, Naoya Sawada et al. · PLoS ONE Open access Aug 2013 29
22 Anti-citrullinated peptide/protein antibody (ACPA)-negative RA shares a large proportion of susceptibility loci with ACPA-positive RA: a meta-analysis of genome-wide association study in a Japanese population Chikashi C. Terao et al. · Arthritis Research & Therapy ReviewOpen access 17 Apr 2015 28
23 Retreatment efficacy and safety of tocilizumab in patients with rheumatoid arthritis in recurrence (RESTORE) study Norihiro Nishimoto et al. · Modern Rheumatology Open access 22 Nov 2013 28
24 Clinical characteristics and variants that predict prognosis of difficult-to-treat rheumatoid arthritis Ichiro Yoshii, Naoya Sawada, Tatsumi Chijiwa · Rheumatology International 11 Apr 2022 23
25 Quantitative effect of HLA-DRB1 alleles to ACPA levels in Japanese rheumatoid arthritis: no strong genetic impact of shared epitope to ACPA levels after stratification of HLA-DRB1*09:01 Chikashi C. Terao, Katsunori Ikari, Koichiro Ohmura et al. · Annals of the Rheumatic Diseases 11 Jan 2012 23
26 CD1a+ survivin+ dendritic cell infiltration in dermal lesions of systemic sclerosis Sho Mokuda, Tatsuhiko Miyazaki, Yoshifumi Ubara et al. · Arthritis Research & Therapy Open access 29 Sep 2015 23
27 Simultaneous quantitative analysis of the expression of CD64 and CD35 on neutrophils as markers to differentiate between bacterial and viral infections in patients with rheumatoid arthritis Sho Mokuda, Osamu Doi, Kiyoshi Takasugi · Modern Rheumatology Sep 2012 22
28 Rheumatoid arthritis in tight disease control is no longer risk of bone mineral density loss Ichiro Yoshii, Tatsumi Chijiwa, Naoya Sawada · Osteoporosis and Sarcopenia Open access Jun 2020 22
29 Measurement of serum amyloid A1 (SAA1), a major isotype of acute phase SAA Yuanyuan Xu, Toshiyuki Yamada, Takahiko Satoh et al. · Clinical Chemistry and Laboratory Medicine (CCLM) 24 Dec 2005 22
30 The proto-oncogene survivin splice variant 2B is induced by PDGF and leads to cell proliferation in rheumatoid arthritis fibroblast-like synoviocytes Sho Mokuda, Tatsuhiko Miyazaki, Yuki Ito et al. · Scientific Reports Open access 22 May 2015 22
31 Ageing: a risk factor for amyloid A amyloidosis in rheumatoid arthritis Yasuaki Okuda, Toshiyuki Yamada, Masaaki Matsuura et al. · Amyloid Jun 2011 21
32 Influence of pain score measured by a visual analog scale ( PS ‐ VAS ) on the Health Assessment Questionnaire Disability Index and 28‐joint Disease Activity Index with C‐reactive protein in rheumatoid arthritis patients Ichiro Yoshii, Tatsumi Chijiwa, Naoya Sawada · International Journal of Rheumatic Diseases 2 Sep 2018 19
33 Post-menopausal women with rheumatoid arthritis who are treated with raloxifene or alendronate or glucocorticoids have lower serum undercarboxylated osteocalcin levels. Sho Mokuda, Yasuhito Okuda, Makoto Onishi et al. · PubMed Jul 2012 19
34 A case of femoral nerve palsy caused by iliopectineal bursitis associated with rheumatoid arthritis Satoshi Mori, Tomoo Tamura, Satoshi Komatsubara et al. · Modern Rheumatology Jul 2004 17
35 An Association Between Amino Acid Position 74 of HLA–DRB1 and Anti–Citrullinated Protein Antibody Levels in Japanese Patients With Anti–Citrullinated Protein Antibody–Positive Rheumatoid Arthritis Chikashi C. Terao et al. · Arthritis & Rheumatology 2 Apr 2015 16
36 Novel autoantibody against the β2‐glycoprotein I/human leucocyte antigen– DR complex in patients with refractory cutaneous ulcers Noriko Arase, Kenji Tanimura, Hui Jin et al. · British Journal of Dermatology 12 Apr 2017 15
37 Tocilizumab improved clinical symptoms of a patient with systemic tophaceous gout who had symmetric polyarthritis and fever: An alternative treatment by blockade of interleukin-6 signaling Sho Mokuda, Masamoto Kanno, Kiyoshi Takasugi et al. · SAGE Open Medical Case Reports Open access 2014 15
38 The frequency of serum amyloid A2 alleles in the Japanese population Toshiyuki Yamada, Yasuaki Okuda, Yoshihisa Itoh · Amyloid 1998 15
39 Serum undercarboxylated osteocalcin level increases with 48 weeks of teriparatide treatment in pre-treated elderly rheumatoid arthritis patients who use anti-resorptive drugs Sho Mokuda, Naoya Sawada, Kenichiro Matoba et al. · Journal of Endocrinological Investigation Oct 2012 15
40 [Pneumocystis carinii pneumonia associated with low dose methotrexate treatment for malignant rheumatoid arthritis]. Yasuhito Okuda, Tetsu Oyama, Hiroko Oyama et al. · PubMed Aug 1995 13
41 Achieving simplified disease activity index remission in patients with active rheumatoid arthritis is associated with subsequent good functional and structural outcomes in a real-world clinical setting under a treat-to-target strategy Fumio Hirano et al. · Modern Rheumatology 6 Dec 2016 11
42 Study on the frequency and risk factors of moderate-to-severe sleep apnea syndrome in rheumatoid arthritis Tomoyuki Mutoh, Yasuaki Okuda, Sho Mokuda et al. · Modern Rheumatology 27 Dec 2015 11
43 Differential affinity of serum amyloid A1 isotypes for high-density lipoprotein Toshiyuki Yamada, Junji Sato, Yasuaki Okuda · Amyloid 19 Nov 2009 11
44 Musculoskeletal ambulation disability symptom complex as a risk factor of incident bone fragility fracture Ichiro Yoshii, Tatsumi Chijiwa, Naoya Sawada et al. · Osteoporosis and Sarcopenia Open access Sep 2021 10
45 Midterm Results of Revision Total Elbow Arthroplasty in Patients with Rheumatoid Arthritis Masuhiro Tomita, Eijiro Adachi, Shunichi Ueda et al. · Clinical Orthopaedics and Related Research 8 Dec 2006 10
46 Impact of sustaining SDAI remission for preventing incident of bone fragility fracture in patient with rheumatoid arthritis Ichiro Yoshii, Naoya Sawada, Tatsumi Chijiwa et al. · Annals of the Rheumatic Diseases 11 Sep 2021 9
47 Screening osteoporotic femoral neck without measuring bone mineral density with the use of tartrate resistant acid phosphatase-5b and serum-creatinine-to-cystatin C ratio in Japanese postmenopausal women Ichiro Yoshii, Tatsumi Chijiwa, Naoya Sawada · Journal of Orthopaedic Science 20 Jul 2019 9
48 Generation and Characterization of Rat Monoclonal Antibodies Against Human Serum Amyloid A Toshiyuki Yamada, Naoto Hirano, Takeshi Kuroda et al. · Scandinavian Journal of Immunology Aug 1997 9
49 [Two cases of rheumatoid arthritis complicated with vasculitis-induced ischemic enterocolitis]. Yukiko Okuda, Kiyoshi Takasugi, Akito Imai et al. · PubMed Oct 1990 8
50 [Clinical study of rheumatoid interstitial lung disease evaluated by high resolution CT]. Yasuhito Okuda, Kenta TAKASUGI, Azusa Imai et al. · PubMed Feb 1993 7

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.