| 1 |
Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines
Clotilde Théry et al. · Journal of Extracellular Vesicles
Open access382 authors |
23 Nov 2018 |
11,535 |
| 2 |
Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing
Brian W. Kunkle et al. · Nature Genetics
ReviewOpen access469 authors |
28 Feb 2019 |
3,277 |
| 3 |
Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis
Stephen J. Sawcer et al. · Nature
Open access241 authors |
Aug 2011 |
2,772 |
| 4 |
New insights into the genetic etiology of Alzheimer’s disease and related dementias
Céline Bellenguez et al. · Nature Genetics
Open access1,266 authors |
Apr 2022 |
2,608 |
| 5 |
Automatic denoising of functional MRI data: Combining independent component analysis and hierarchical fusion of classifiers
Gholamreza Salimi‐Khorshidi, Gwenaëlle Douaud, Christian F. Beckmann et al. · NeuroImage
Open access |
3 Jan 2014 |
2,049 |
| 6 |
Integrated information theory: from consciousness to its physical substrate
Giulio Tononi, Mélanie Boly, Marcello Massimini et al. · Nature reviews. Neuroscience
Review |
26 May 2016 |
1,815 |
| 7 |
Adherence to Mediterranean diet and health status: meta-analysis
Francesco Sofi, Francesca Cesari, Rosanna Abbate et al. · BMJ
Open access |
11 Sep 2008 |
1,733 |
| 8 |
Resting-state fMRI in the Human Connectome Project
Stephen M. Smith et al. · NeuroImage
Open access |
20 May 2013 |
1,730 |
| 9 |
Neural correlates of consciousness: progress and problems
Christof Koch, Marcello Massimini, Mélanie Boly et al. · Nature reviews. Neuroscience
Review |
20 Apr 2016 |
1,689 |
| 10 |
Accruing evidence on benefits of adherence to the Mediterranean diet on health: an updated systematic review and meta-analysis
Francesco Sofi, Rosanna Abbate, Gian Franco Gensini et al. · American Journal of Clinical Nutrition
ReviewOpen access |
Sep 2010 |
1,610 |
| 11 |
ICA-based artefact removal and accelerated fMRI acquisition for improved resting state network imaging
Ludovica Griffanti, Gholamreza Salimi‐Khorshidi, Christian F. Beckmann et al. · NeuroImage
Open access |
22 Mar 2014 |
1,480 |
| 12 |
Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis
Ashley Harris Beecham et al. · Nature Genetics
Open access193 authors |
29 Sep 2013 |
1,466 |
| 13 |
A Theoretically Based Index of Consciousness Independent of Sensory Processing and Behavior
Adenauer Girardi Casali, Olivia Gosseries, Mario Rosanova et al. · Science Translational Medicine
Open access |
14 Aug 2013 |
1,328 |
| 14 |
Physical activity and risk of cognitive decline: a meta-analysis of prospective studies
Francesco Sofi, Debora Valecchi, Duccio Bacci et al. · Journal of Internal Medicine
ReviewOpen access |
30 Aug 2010 |
1,233 |
| 15 |
Genome-wide association study identifies eight risk loci and implicates metabo-psychiatric origins for anorexia nervosa
Anorexia Nervosa Genetics Initiative et al. · Nature Genetics
Open access211 authors |
15 Jul 2019 |
1,213 |
| 16 |
2016 SOSORT guidelines: orthopaedic and rehabilitation treatment of idiopathic scoliosis during growth
Stefano Négrini et al. · Scoliosis and Spinal Disorders
Open access |
10 Jan 2018 |
1,203 |
| 17 |
Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease
Rebecca C. Sims et al. · Nature Genetics
Open access450 authors |
17 Jul 2017 |
1,122 |
| 18 |
Mediterranean diet and multiple health outcomes: an umbrella review of meta-analyses of observational studies and randomised trials
Monica Gabriela Dinu, Giuditta Pagliai, Alessandro Casini et al. · European Journal of Clinical Nutrition
Open access |
10 May 2017 |
1,031 |
| 19 |
Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition)
Andrea Cossarizza et al. · European Journal of Immunology
Open access436 authors |
Oct 2019 |
1,014 |
| 20 |
Mediterranean diet and health status: an updated meta-analysis and a proposal for a literature-based adherence score
Francesco Sofi, Claudio Macchi, Rosanna Abbate et al. · Public Health Nutrition
Open access |
29 Nov 2013 |
1,011 |
| 21 |
Vegetarian, vegan diets and multiple health outcomes: A systematic review with meta-analysis of observational studies
Monica Gabriela Dinu, Rosanna Abbate, Gian Franco Gensini et al. · Critical Reviews in Food Science and Nutrition
Review |
6 Feb 2016 |
991 |
| 22 |
Carpal tunnel syndrome: clinical features, diagnosis, and management
Luca Padua, Daniele Coraci, Carmen Erra et al. · The Lancet Neurology
|
11 Oct 2016 |
894 |
| 23 |
Adverse effects of biologics: a network meta-analysis and Cochrane overview
Jasvinder A. Singh et al. · Cochrane Database of Systematic Reviews
Open access |
4 Feb 2011 |
829 |
| 24 |
Subsystems Contributing to the Decline in Ability to Walk: Bridging the Gap Between Epidemiology and Geriatric Practice in the InCHIANTI Study
Luigi Ferrucci, Stefania Bandinelli, Enrico Benvenuti et al. · Journal of the American Geriatrics Society
|
Dec 2000 |
818 |
| 25 |
Molecular Evolution of Human Coronavirus Genomes
Diego Forni, Rachele Cagliani, Mario Salvatore Clerici et al. · Trends in Microbiology
ReviewOpen access |
19 Oct 2016 |
793 |
| 26 |
Blood pressure and heart rate variabilities in normotensive and hypertensive human beings.
Giuseppe Mancia, Alberto U. Ferrari, Luisa Gregorini et al. · Circulation Research
Open access |
Jul 1983 |
780 |
| 27 |
Cognitive impairment in multiple sclerosis: clinical management, MRI, and therapeutic avenues
Ralph H. B. Benedict, Maria Pia Amato, John DeLuca et al. · The Lancet Neurology
Open access |
16 Sep 2020 |
779 |
| 28 |
Burden of 375 diseases and injuries, risk-attributable burden of 88 risk factors, and healthy life expectancy in 204 countries and territories, including 660 subnational locations, 1990–2023: a systematic analysis for the Global Burden of Disease Study 2023
Simon I Hay et al. · The Lancet
Open access2,780 authors |
Oct 2025 |
762 |
| 29 |
Natural Frequencies of Human Corticothalamic Circuits
Mario Rosanova, Adenauer Girardi Casali, Valentina Bellina et al. · Journal of Neuroscience
Open access |
17 Jun 2009 |
757 |
| 30 |
Stair ascent and descent at different inclinations
Robert Riener, Marco Rabuffetti, C. Frigo · Gait & Posture
|
Feb 2002 |
755 |
| 31 |
European Academy of Neurology guideline on the diagnosis of coma and other disorders of consciousness
Daniel Kondziella, Andreas Bender, Karin Diserens et al. · European Journal of Neurology
Open access |
23 Feb 2020 |
734 |
| 32 |
Insomnia and risk of cardiovascular disease: a meta-analysis
Francesco Sofi, Francesca Cesari, Alessandro Casini et al. · European Journal of Preventive Cardiology
Review |
31 Aug 2012 |
727 |
| 33 |
Review of assistive strategies in powered lower-limb orthoses and exoskeletons
Tingfang Yan, Marco Cempini, Calogero Maria Oddo et al. · Robotics and Autonomous Systems
|
17 Nov 2014 |
723 |
| 34 |
Occurrence of carbapenemase-producing Klebsiella pneumoniae and Escherichia coli in the European survey of carbapenemase-producing Enterobacteriaceae (EuSCAPE): a prospective, multinational study
Hajo Grundmann et al. · The Lancet Infectious Diseases
Open access |
18 Nov 2016 |
689 |
| 35 |
How many people are able to control a P300-based brain–computer interface (BCI)?
Christoph Guger, Shahab Daban, Eric W. Sellers et al. · Neuroscience Letters
|
22 Jun 2009 |
655 |
| 36 |
Uncovering the heterogeneity and temporal complexity of neurodegenerative diseases with Subtype and Stage Inference
Alexandra L. Young et al. · Nature Communications
Open access380 authors |
9 Oct 2018 |
613 |
| 37 |
A method for positioning electrodes during surface EMG recordings in lower limb muscles
Alberto Rainoldi, G Melchiorri, I. Caruso · Journal of Neuroscience Methods
|
31 Dec 2003 |
613 |
| 38 |
A review of technologies and performances of thermal treatment systems for energy recovery from waste
Lidia Lombardi, Ennio Antonio Carnevale, Andrea Corti · Waste Management
|
19 Dec 2014 |
604 |
| 39 |
Are the Neural Correlates of Consciousness in the Front or in the Back of the Cerebral Cortex? Clinical and Neuroimaging Evidence
Mélanie Boly, Marcello Massimini, Naotsugu Tsuchiya et al. · Journal of Neuroscience
Open access |
4 Oct 2017 |
603 |
| 40 |
Acid sphingomyelinase activity triggers microparticle release from glial cells
Fabio Bianco, Cristiana Perrotta, Luisa Novellino et al. · The EMBO Journal
Open access |
19 Mar 2009 |
595 |
| 41 |
Breakdown in cortical effective connectivity during midazolam-induced loss of consciousness
Fabio Ferrarelli, Marcello Massimini, Simone Sarasso et al. · Proceedings of the National Academy of Sciences
Open access |
25 Jan 2010 |
585 |
| 42 |
Guidelines for the use of flow cytometry and cell sorting in immunological studies *
Andrea Cossarizza et al. · European Journal of Immunology
Open access236 authors |
Oct 2017 |
560 |
| 43 |
Microbes and Alzheimer’s Disease
Ruth F. Itzhaki et al. · Journal of Alzheimer s Disease
Open access |
8 Mar 2016 |
547 |
| 44 |
Myelin-oligodendrocyte glycoprotein antibody-associated disease
Romain Marignier et al. · The Lancet Neurology
Open access |
18 Aug 2021 |
540 |
| 45 |
Reduced Sleep Spindle Activity in Schizophrenia Patients
Fabio Ferrarelli, Reto Huber, Michael J. Peterson et al. · American Journal of Psychiatry
|
Mar 2007 |
527 |
| 46 |
Cardiovascular Death and Nonfatal Myocardial Infarction in Acute Coronary Syndrome Patients Receiving Coronary Stenting Are Predicted by Residual Platelet Reactivity to ADP Detected by a Point-of-Care Assay
Rossella Marcucci, Anna Maria Gori, Rita Paniccia et al. · Circulation
|
2009 |
521 |
| 47 |
Stratification of unresponsive patients by an independently validated index of brain complexity
Silvia Casarotto, Angela Comanducci, Mario Rosanova et al. · Annals of Neurology
Open access |
22 Sep 2016 |
518 |
| 48 |
How to measure baroreflex sensitivity
Gianfranco Parati, Marco Di Rienzo, Giuseppe Mancia · Journal of Hypertension
|
2000 |
518 |
| 49 |
Global burden of 292 causes of death in 204 countries and territories and 660 subnational locations, 1990–2023: a systematic analysis for the Global Burden of Disease Study 2023
Mohsen Naghavi et al. · The Lancet
Open access2,463 authors |
Oct 2025 |
500 |
| 50 |
The NLRP3 and NLRP1 inflammasomes are activated in Alzheimer’s disease
Marina Saresella, Francesca La Rosa, Federica Piancone et al. · Molecular Neurodegeneration
Open access |
3 Mar 2016 |
497 |